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Identification of candidate genes for bipolar disorder and schizophrenia using DNA microarray

Research Project

Project/Area Number 13470194
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Psychiatric science
Research InstitutionBrain Science Institute, RIKEN

Principal Investigator

KATO Tadafumi  Laboratory for Molecular Dynamics of Mental Disorders, Brain Science Institute, RIKEN, Laboratory Head, 精神疾患動態研究チーム, チームリーダー (30214381)

Project Period (FY) 2001 – 2002
Project Status Completed (Fiscal Year 2002)
Budget Amount *help
¥13,000,000 (Direct Cost: ¥13,000,000)
Fiscal Year 2002: ¥6,300,000 (Direct Cost: ¥6,300,000)
Fiscal Year 2001: ¥6,700,000 (Direct Cost: ¥6,700,000)
KeywordsBipolar Disorder / Schizophrenia / DNA microarray / Gene Expression / 遺伝子発現 / DNAマイクロアレイ / 脳 / 躁うつ病 / 精神分裂病
Research Abstract

Using DNA microarray, we examined gene expression patterns in postmortem brain samples of patients with bipolar disorder and schizophrenia, and controls. Differentially expressed genes were compared with each other. By the cluster analysis, bipolar disorder and controls were well separated. The genes identified by this study needs to be verified further.

Report

(3 results)
  • 2002 Annual Research Report   Final Research Report Summary
  • 2001 Annual Research Report
  • Research Products

    (8 results)

All Other

All Publications (8 results)

  • [Publications] Kato T, Iwamoto K, Washizuka S, Mori K, Tajima O, Akiyarna T, Nanko S, Kunugi H, Kato N: "No association of mutations and mRNA expression of WFS1/wolframin with bipolar disorder"Neuroscience Letters. 338. 21-24 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] 加藤忠史: "DNAマイクロアレイの精神疾患の臨床検査法への応用可能性"精神科. 1巻5号. 424-426 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] 加藤忠史: "精神疾患領域における分子医学"ファルマシア. 38巻8号. 727-731 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] 加藤忠史, 岡崎祐士: "統合失調症(精神分裂病)へのポストゲノム的アプローチ"実験医学. 21. 42-46 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] 加藤忠史: "躁うつ病の脳科学の現状と課題"作業療法ジャーナル. 36巻9号. 1093-1097 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Kato T, Iwamoto K, Washizuka S, Mori K, Tajima O, Akiyama T, Nanko S, Kunugi H, Kato N: "No association of mutations and mRNA expression of WFS1/wolframin with bipolar disorder"Neuroscience Letters. 3381. 21-24 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Kato, T., Iwamoto, K., Washizuka, S., Mori, K., Tajima, O., Akiyama, T., Nanko, S., Kunugi, H., Kato, N.: "No association of mutations and mRNA expression of WFS1/wolframin with bipolar disorder"Neuroscience Letters. (in press).

    • Related Report
      2002 Annual Research Report
  • [Publications] 加藤忠史: "DNAマイクロアレイの精神疾患の臨床検査法への応用可能性"精神科. 1・5. 424-426 (2002)

    • Related Report
      2002 Annual Research Report

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Published: 2001-04-01   Modified: 2016-04-21  

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