| Project/Area Number |
13554028
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 展開研究 |
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| Research Field |
物質変換
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| Research Institution | CHIBA UNIVERSITY |
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Principal Investigator |
TOGO Hideo Chiba University, Department of Chemistry Faculty of Science, Associate Professor, 理学部, 助教授 (60217461)
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| Co-Investigator(Kenkyū-buntansha) |
KAIHO Tasuo Mitsui Chemicals Co., Material Chemicals Lab., Chief Researcher, 有機機能材料研究所, 主席研究員
YAMAGUCHI Kentaro Chiba University, Chemical Analysis Center, Associate Professor, 分析センター, 助教授 (50159208)
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| Project Period (FY) |
2001 – 2003
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| Project Status |
Completed (Fiscal Year 2003)
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| Budget Amount *help |
¥5,900,000 (Direct Cost: ¥5,900,000)
Fiscal Year 2003: ¥1,500,000 (Direct Cost: ¥1,500,000)
Fiscal Year 2002: ¥1,300,000 (Direct Cost: ¥1,300,000)
Fiscal Year 2001: ¥3,100,000 (Direct Cost: ¥3,100,000)
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| Keywords | Alcohol / Ketone / Aldehyde / Environmental Benign / Polymer-supported Hypervalent Iodine / リサイクル / カルボン酸 / 高分子型超原子価ヨウ素酸化 |
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| Research Abstract |
Primary and secondary alcohols were successfully oxidized to the corresponding aldehydes and ketones at room temperature in good yields, respectively, with poly[4-(diacetoxyiodo)styrene] (PSDIB) in the presence of TEMPO (cat.) in acetone, as an environmentally friendly method. Here, polymer-supported hypervapent iodine was quantitatively recovered by simple filtration from the reaction mixture, and PSDIB was regenerated by treatment with peracetic acid and reused successfully. The previous methods such as Swern oxidation and Dess-Martin oxidation may be substituted by the present method, since the present oxidation of primary and secondary alcohols to the corresponding aldehydes and ketones, respectively, is effective and secure as an operationally simple and environmentally benign method, and can be used for the synthesis of pharmaceutical and agrochemical substances
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