| Project/Area Number |
13557182
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 展開研究 |
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| Research Field |
矯正・小児・社会系歯学
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| Research Institution | Osaka University |
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Principal Investigator |
NAGATA Hideki Osaka University, Graduate School of Dentistry, Associate Professor, 大学院・歯学研究科, 助教授 (50260641)
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| Co-Investigator(Kenkyū-buntansha) |
KITA Junichi Shimadzu Corporation, Analytical Instruments Division, Manager, 分析機器事業部技術部, 主任技師(研究職)
SHIZUKUISHI Satoshi Osaka University, Graduate School of Dentistry, Professor, 大学院・歯学研究科, 教授 (00028789)
TANAKA Muneo Osaka University, Dental Hospital, Assistant Professor, 歯学部附属病院, 講師 (90263300)
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| Project Period (FY) |
2001 – 2002
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| Project Status |
Completed (Fiscal Year 2002)
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| Budget Amount *help |
¥8,000,000 (Direct Cost: ¥8,000,000)
Fiscal Year 2002: ¥2,200,000 (Direct Cost: ¥2,200,000)
Fiscal Year 2001: ¥5,800,000 (Direct Cost: ¥5,800,000)
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| Keywords | electronic nose / volatile sulfur compaund / metal oxide semiconductor / gas diromatography / organoleptic test / におい分析装置 / ガスクロマトグラフィー |
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| Research Abstract |
In this study, we attempt to evaluate malodor with a new type of electronic nose which combined with the preconcentrator and six metal oxide semiconductor sensor array. The subject population consisted of 55 patients who complained of oral malodor. Oral malodor was assessed a concentration of volatile sulfur compaunds (VSC) measured by gas chromatography, organoleptic test (OLT) and predicted OLT score (EN-OL1). EN-OLT score was estimated as malodor strength by the multiple linear regression method using a new type of electronic nose system. The correlation coefficient between EN-OLT and OLT score (r=0.71) was higher than that between VSC and OLT score. Gender, age, smoking, alcohol consumption, PPD, TCS and PCR as independent variables were used in linear and logistic regression analyses. In linear regression analyses, the explanatory power of these independent variables showed 37% for EN-OLT score, 16% for GC-VSC and 32% for OLT score. In logistic regression analyses on possibility of subjects being in upper 25th percentile of EN-OLT score distribution as a dependent variable, PPD, TCS and PCR showed significant associations and their odds ratios were 17.1 and 12.4 and 28.0, respectively. In conclusion, oral malodor strength measured with the electronic nose may be useful for evaluating clinically oral malodor and may be associated with periodontal status, tongue coating and oral hygiene status.
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