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Development of a SIgA measurement kit for monitoring of risk of URTI

Research Project

Project/Area Number 13558003
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section展開研究
Research Field 体育学
Research InstitutionUniversity of Tsukuba (2003)
The University of Tokyo (2001-2002)

Principal Investigator

KONO Ichiro (2003)  University of Tsukuba, Institute of Health & Sport Sciences, Professor, 体育科学系, 教授 (00132994)

秋本 崇之 (2001-2002)  東京大学, 大学院・総合文化研究科, 助手 (00323460)

Co-Investigator(Kenkyū-buntansha) AKAMA Takeo  Japan Woman's College of Physical Education, Department of Physical Education, Associate Professor, 体育学部, 助教授 (60212411)
河野 一郎  筑波大学, 体育科学系, 教授 (00132994)
福林 徹  東京大学, 大学院・総合文化研究科, 教授 (70114626)
Project Period (FY) 2001 – 2003
Project Status Completed (Fiscal Year 2003)
Budget Amount *help
¥5,700,000 (Direct Cost: ¥5,700,000)
Fiscal Year 2003: ¥1,200,000 (Direct Cost: ¥1,200,000)
Fiscal Year 2002: ¥2,900,000 (Direct Cost: ¥2,900,000)
Fiscal Year 2001: ¥1,600,000 (Direct Cost: ¥1,600,000)
KeywordsURTI / SIgA / sports / athletes / immunity / saliva / 免疫 / 感染症 / スポーツ / 運動 / 局所免疫 / 唾液
Research Abstract

Development of SIgA kit
We tried to develop a SIgA measurement kit by using commercially available monoclonal antibody. However, we could not develop an optimal system of SIgA measurement, because of the titer and/or epitope of monoclonal antibody. So, we are trying to make some monoclonal antibodies to be able to use TIA. Now we are screening the antibody
Determination of the relationship between SIgA level and URTI
Our research which we pointed out the relationship between SIgA and URTI, was published in Japanese Journal of Clinical Sports Medicine. Furthermore, another research which dealt with changes of SIgA and physical and mental stress was published in Medicine and Science in Spurts and Exercise. Resulting from this study, we clarified that there is a certain relationship between SIgA level and risk of URTI, we may be able to apply the relationship to prevent URTI in athletes

Report

(4 results)
  • 2003 Annual Research Report   Final Research Report Summary
  • 2002 Annual Research Report
  • 2001 Annual Research Report
  • Research Products

    (9 results)

All Other

All Publications (9 results)

  • [Publications] Takayuki Akimoto, Chikako Nakahori, Katuji Aizawa, Fumimori Kimura, Toru Fukubayashi, Ichiro Kono: "Acupuncture and Responses of Immunologic and Endocrine Markers during Competition"Med.& Sci.in Sports & Exerc.. 35(8). 1296-1302 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] T Akimoto, Y Kumai, T Akama, E Hayashi, H Murakami, R Soma, S Kuno, I Kono: "affects of 12 months of exercise training on salivary secretory IgA levels in elderly subjects"Br.J.Sports Med.. 37(2). 76-79 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] akayuki Akimoto, Chikako Nakahori, Katuji Aizawa, Fumimori Kimura, Toru Fukubayashi, Ichiro K ono: "Acupuncture and Responses of Immunologic and Endocrine Markers during Competition"Med.& Sci.in Sports & Exerc.. 35(8). 1296-1302 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] T Akimoto, Y Kumai, T Akama, E Hayashi, H Murakami, R Soma, S Kuno, I Kono: "Effects of 12 months of exercise training on salivary secretory IgA levels in elderly subjects"Br.J.Sports Med.. 37(2). 76-79 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Takayuki Akimoto, Chikako Nakahori, Katsuji Aizawa, Fumimori Kimura, Toru Fukubayashi, Ichiro Kono: "Acupuncture and Responses of Immunologic and Endocrine Markers during Competition"Med. & Sci. in Sports & Exerc.. 35(8). 1296-1302 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] T Akimoto, Y Kumai, T Akama, E Hayashi, H Murakami, R Soma, S Kuno, I Kono: "Effects of 12 months of exercise training on salivary secretory IgA levels in elderly subjects"Br.J. Sports Med.. 37(2). 76-79 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 中村大輔, 秋本崇之: "大学サッカー選手における唾液中SIgAを用いた上気道感染症予防の試み"日本臨床スポーツ医学会誌. 10(3). 445-450 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Akimoto T, Kumai Y, Akama T, Hayashi E, Murakami H, Soma R, Kuno S, Kono I: "Effects of 12 months of exercise training on salivary secretory IgA levels in elderly subjects"Br. J. Sports Med. 37(1). 77-80 (2003)

    • Related Report
      2002 Annual Research Report
  • [Publications] 秋本崇之, 扇原淳: "運動は免疫能を向上させるか?疫学によるエビデンス"臨床スポーツ医学. 19(11). 1283-1287 (2002)

    • Related Report
      2002 Annual Research Report

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Published: 2001-04-01   Modified: 2016-04-21  

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