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A study on neuropathology of AIDS patients in Africa

Research Project

Project/Area Number 13576021
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section海外学術
Research Field Legal medicine
Research InstitutionSaga University

Principal Investigator

KIBAYASHI Kazuhiko  Saga University, Faculty of Medicine, Professor, 医学部, 教授 (20244113)

Co-Investigator(Kenkyū-buntansha) YONEMITSU Kose  Kumamoto University, Faculty of Medicine, Lecturer, 医学部, 講師 (10128332)
SHOJO Hideki  Saga University, Faculty of Medicine, Research Associate, 医学部, 助手 (60284626)
TSUNENARI Shigeyuki  Kumamoto University, Faculty of Medicine, Professor, 医学部, 教授 (80040202)
Project Period (FY) 2001 – 2003
Project Status Completed (Fiscal Year 2003)
Budget Amount *help
¥13,500,000 (Direct Cost: ¥13,500,000)
Fiscal Year 2003: ¥3,400,000 (Direct Cost: ¥3,400,000)
Fiscal Year 2002: ¥3,100,000 (Direct Cost: ¥3,100,000)
Fiscal Year 2001: ¥7,000,000 (Direct Cost: ¥7,000,000)
Keywordsinternational exchange of researchers / Tanzania / AIDS / HIV / neuropathology / tuberculosis / cryoticococosis / toxoplasmosis / HIV脳炎
Research Abstract

The objective of this study was to examine the neuropathological changes in the brain of patients infected with human immunodeficiency virus (HIV) in Dar es Salaam, Tanzania. HIV infection was identified in 78 (35.8%) of 218 patients selected from forensic autopsies. Neuropathological findings were observed in 35 (44.9%) of 78 HIV infected patients these include lymphocytic meningitis 20, bacterial meningitis 3, tuberculous brain abscess 4, toxoplasma encephalitis 3, cryptococcal meningitis 2, basal ganglia calcification 3. HIV encephalitis, lymphoma, and cytomegalovirus encephalitis could not be found in this study. These results provided information on the likely diagnostic possibilities to be considered in the evaluation and management of HIV infected patients with neurological symptoms in Tanzania.

Report

(4 results)
  • 2003 Annual Research Report   Final Research Report Summary
  • 2002 Annual Research Report
  • 2001 Annual Research Report
  • Research Products

    (23 results)

All Other

All Publications (23 results)

  • [Publications] Ng'walali PM: "Toxoplasma encephalitis in HIV"East African Medical Journal. 78. 275-276 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Kibayashi K: "Incipient Alzheimer's disease as the underlying cause of a motor vehicle crash"Medicine, Science and the Law. 42. 233-236 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Ng'walali PM: "Neuropathological diagnosis of Alzheimer's disease in forensic autopsy of elderly persons with fatal accident"Legal Medicine. 4. 223-231 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Kibayashi K: "Accidental fatal hypothermia in elderly people with Alzheimer's disease"Medicine, Science and the Law. 43. 127-131 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Kibayashi K: "Heat-induced immunoreactivity of tau protein in neocortical neurons in fire fatalities"International Journal of Legal Medicine. 117. 282-286 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Ng'walali PM: "Toxoplasma encephalitis in HIV"East African Medical Journal. 78. 275-276 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Kibayashi K: "Incipient Alzheimer's disease as the underlying cause of a motor vehicle crash"Medicine, Science and the Law. 42. 233-236 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Ng'walali PM: "Neuropathological diagnosis of Alzheimer's disease in forensic autopsy of elderly persons with fatal accident"Legal Medicine. 4. 223-231 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Kibayashi K: "Accidental fatal hypothermia in elderly people with Alzheimer's disease"Medicine, Science and the Law. 43. 127-131 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Kibayashi K: "Heat-induced immunoreactivity of tau protein in neocortical neurons in fire fatalities"International Journal of Legal Medicine. 117. 282-286 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Kibayashi K: "Accidental fatal hypothermia in elderly people with Alzheimer's disease."Medicine, Science and the Law. 43・2. 127-131 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] Kibayashi K: "Patterned injuries in children who have suffered repeated physical abuse."Pediatrics International. 45・2. 193-195 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] Kibayashi K: "Heat-induced immunoreactivity of tau protein in neocortical neurons in fire fatalities."International Journal of Legal Medicine. 117・5. 282-286 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] Kibayashi K: "Incipient Alzheimer's disease as the underlying cause of a motor vehicle crash."Review Series Dementia. 4. 14-15 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] Kibayashi K: "Traumatic basal ganglia hematoma in a fatal traffic accident victim"Legal Medicine. 4(2). 127-130 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Kibayashi K: "Incipient Alzheimer's disease as the underlying cause of a motor vehicle crash"Medicine, Science and the Law. 42(3). 233-236 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Ng'walali PM: "Neuropathological diagnosis of Alzheimer's disease in forensic autopsy of elderly persons with fatal accident"Legal Medicine. 4(4). 223-231 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Kibayashi K: "Patterned injuries in children who have suffered repeat physical abuse"Pediatrics International. (in press).

    • Related Report
      2002 Annual Research Report
  • [Publications] Kibayashi K: "Accidental fatal hypothermia in elderly with Alzheimer's disease"Medicine, Science and the Law. (in press).

    • Related Report
      2002 Annual Research Report
  • [Publications] 木林和彦: "社会医学的にみたアジアにおけるエイズウイルス感染の広がりと病理所見に関する調査研究"上原記念生命科学財団研究報告集. 16. 69-70 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Ng'walali PM: "Toxoplasma encephalitis in HIV"East African Medical Journal. 78. 275-276 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Kibayashi K: "Traumatic basal ganglia hematoma in a fatal traffic accident victim"Legal Medicine. (in press).

    • Related Report
      2001 Annual Research Report
  • [Publications] 木林 和彦: "若年型パーキンソン病患者の交通事故死例:乗車位置と運転能力の検討"法医病理. 7. 25-29 (2001)

    • Related Report
      2001 Annual Research Report

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Published: 2001-04-01   Modified: 2016-04-21  

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