| Project/Area Number |
13650765
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Structural/Functional materials
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| Research Institution | Sophia University |
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Principal Investigator |
TAKAI Kenichi (2002) Sophia Univ., Faculty of Science and Engineering, Assist. Prof., 理工学部, 助教授 (50317509)
野末 章 (2001) 上智大学, 理工学部, 教授 (80146802)
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| Co-Investigator(Kenkyū-buntansha) |
HISAMORI Noriyuki Sophia Univ., Faculty of Science and Engineering, Research Assistant, 理工学部, 助手 (80317510)
高井 健一 上智大学, 理工学部, 講師 (50317509)
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| Project Period (FY) |
2001 – 2002
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| Project Status |
Completed (Fiscal Year 2002)
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| Budget Amount *help |
¥3,600,000 (Direct Cost: ¥3,600,000)
Fiscal Year 2002: ¥1,200,000 (Direct Cost: ¥1,200,000)
Fiscal Year 2001: ¥2,400,000 (Direct Cost: ¥2,400,000)
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| Keywords | Bone-like composite / Hydroxyap atite / HA / PMMA composite / In vitro Examination / In vivo Examination / Titanium alloys / Fracture toughness |
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| Research Abstract |
The number of diseases relating to the bones, such as osteoporosis, increases with aging in the society year by year. According to the report on an investigation of the Ministry of Health, Labor and Welfare, the number of patients who is diagnosed, as osteoporosis will be approximately 12.5 million in 2010 and approximately 80% are women among these patients. Thus the osteoporosis may be regarded as a national disease in Japan that faces the aging society.
In the twenty-first century, advanced needs will arise for the higher performance artificial bones. The requirement for the applied parts, however, may be different from bone to bone, because the number of bones in the human body is as large as 206. The functions that are required to substitute the materials for human hard tissues are directed not only toward the biocompatibility/bioaffinity but also toward the high mechanical strength, high fracture toughness, and low Young's modulus. The present project is aimed at the fabrications of high loading parts (hip joints) and low loading parts (substitute materials for bones). Among the present subjects listed below, Subject (1) includes the fabrication of the biocompatible and high loading parts, whereas Subjects (2) and (3) include the fabrication of low loading parts :
(1) Coating process and evaluation
(2) Formation process of self-restoration function
(3) Processing of bone-like composites and evaluation
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