| Project/Area Number |
13650933
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
高分子合成
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| Research Institution | TOYOHASHI UNIVERSITY OF TECHNOLOGY |
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Principal Investigator |
ITSUNO Shinichi Toyohashi University of Technology, Professor, 工学部, 教授 (50158755)
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| Project Period (FY) |
2001 – 2002
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| Project Status |
Completed (Fiscal Year 2002)
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| Budget Amount *help |
¥3,500,000 (Direct Cost: ¥3,500,000)
Fiscal Year 2002: ¥1,000,000 (Direct Cost: ¥1,000,000)
Fiscal Year 2001: ¥2,500,000 (Direct Cost: ¥2,500,000)
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| Keywords | Asymmetric allylation polymerization / Asymmetric aldol polymerization / Sakurai-Hosomi allylation / Mukaiyama aldol reaction / Chiral derivatization / Bis(allylsilane) / Bis(enol silane) / Dialdehyde |
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| Research Abstract |
The synthesis of optically active polymers having main chain configurational chirality is an important technology, which is essential for the molecular design of the next generation polymeric materials. A great number of methods for enantioselective transformations including C-C bond forming reactions have been extensively studied. If an asymmetric C-C bond forming reaction proceeds in quantitative conversion without any side reactions, it can be used for optically active polymer synthesis. We have found that the enantioselective addition of allylsilane to an aldehyde (Sakurai-Hosomi allylation reaction) and the enantioselective addition of enol silane to an aldehyde (Mukaiyama aldol reaction) are suitable reaction for the synthesis of optically active polymers. Repetitive Sakurai-Hosomi allylation between bis(allylsilane) and dialdehyde produced a polymer having a chiral homoallylic alcohol unit structure. When a chirally modified Lewis acid catalyst was used, optically active polymers having main chain configurational chirality was obtained. Similarly, repetitive Mukaiyama aldol reaction between bis(enolsilane) andaldehyde produced a polymer having a chiral β-hydroxy carbonyl unit structure.
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