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Development of an imaging system to determine the three-dimensional structure of arteries using synchrotron radiation monochromatic X-rays

Research Project

Project/Area Number 13670975
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Radiation science
Research InstitutionHIGH ENERGY ACCELERATOR RESEARCH ORGANIZATION

Principal Investigator

HYODO Kazuyuki  HIGH ENERGY ACCELERATOR RESEARCH ORGANIZATION Institute of materials structure science, Assistant, 物質構造科学研究所, 助手 (60201729)

Co-Investigator(Kenkyū-buntansha) OTSUKA Sadanori  HIGH ENERGY ACCELERATOR RESEARCH ORGANIZATION Institute of Clinical Sciences University of Tsukuba, Lecturer, 臨床医学系, 講師 (40241814)
ANDO Masami  HIGH ENERGY ACCELERATOR RESEARCH ORGANIZATION Institute of materials structure science, Professor, 物質構造科学研究所, 教授 (30013501)
Project Period (FY) 2001 – 2002
Project Status Completed (Fiscal Year 2002)
Budget Amount *help
¥3,100,000 (Direct Cost: ¥3,100,000)
Fiscal Year 2002: ¥800,000 (Direct Cost: ¥800,000)
Fiscal Year 2001: ¥2,300,000 (Direct Cost: ¥2,300,000)
KeywordsSynchrotron Radiation / X-ray Optics / Coronary Angiography / Laue Crystal / Monochromnatic X-ray / stereo-imaging / Micro-angiography / 立体情報 / 心血管系 / ステレオペア
Research Abstract

In comparison with the conventional radiography, drastic improvement in spatial resolution and density resolution on the X-ray image are expected, imaging systems for the purpose of the diagnosis of cardiovascular system, cancers, metabolism in the brain, bones fine structure, etc. using synchrotron radiation monochromatic X-rays are developing in synchrotron radiation facilities in the world. In those systems, the irradiation direction of monochromatic X-rays to an object will be limited by characteristics of generating synchrotron radiation beam from an accelerator. Therefore, there is a case in which it becomes a problem, when the overlap of arterial system and soft tissue makes an X-ray projection image. It seems to be very useful to obtain information of the three-dimensional structure of cardiovascular system in case of angiography using synchrotron radiation.
The purpose of this study is the development of method for reducing the overlap of the cardiovascular system on the X-ray projection image by using a Laue crystal (1) or rotating an object at very low speed (2). Preliminary experiments on stereo-imaging were performed to determine the three-dimensional structure of coronary arteries for intravenous coronary angiography and also micro-angiography using synchrotron radiation produced by a bending magnet at the PF-AR, KEK and also a vertical wiggler at the PF, KEK. The possibility of these two methods was confirmed. It is expected that the result can be applied to the other imaging methods including the new imaging method using X-ray refraction.

Report

(3 results)
  • 2002 Annual Research Report   Final Research Report Summary
  • 2001 Annual Research Report
  • Research Products

    (17 results)

All Other

All Publications (17 results)

  • [Publications] 兵藤一行: "放射光単色X線を用いた造影剤の静脈注入による冠動脈診断システム"日本写真学会誌. 65(7). 490-494 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Sadanori OHTSUKA: "Clinical application of synchrotron radiation to intravenous coronary angiography at PF-AR"Photon Factory Activity Report. 18. 43-44 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Kazuyuki HYODO: "Intravenous coronary angiography system II at the PF-AR"Abstract of The Internaional Workshop on Recent Advances in Medical Applications of Synchrotron Radiation. 8-9 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] 兵藤一行: "放射光単色X線を用いた医学・生物学応用のためのイメージング法の開発"放射線. 28(4). 269-280 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Kazuyuki HYODO: "Development of the two-dimensional intravenous coronary angiography system II at the PF-AR NE1, KEK"Abstract of the 5th Harima International Forum. 30 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] 兵藤一行: "2次元医学診断システムにおける被写体の立体的情報を得るための試み"第15回日本放射光学会報文集. 117 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] K. Hyodo and M. Ando: "Intravenous coronary angiography system using monochromatic synchrotron radiation X-rays"Journal of The Society of Photographic Science and Technology of Japan. 65(7) (in Japanese). 490-494 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] M. Ando, K. Hyodo, H. Sugiyama, A. Maksimenko, W. Pattanasiriwisawa, K. Mori, J. Robertson, E. Rubenstein and Y. Tanaka: "X-Ray Optics 'Owl' and 'Trinity1'"Jpn. J. Appl. Phys.. 41. 4742-4746 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] K. Hyodo, M. Ando, S. Ohtsuka, I. Yamaguchi, T. Takeda and Y. Itai: "Intravenous coronary angiography system II at the PF-AR"Abstract of the International Workshop on Recent Advances in Medical Applications of Synchrotron Radiation. 8-9 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] K. Hvodo, M. Ando, S. Yamamoto, S. Ohtsuka, I. Yamaguchi, T. Takeda, and Y. Itai: "Development of the two-dimensional intravenous coronary angiography system II at the PF-AR NE1, KEK"Abstract of the 5th Harima International Forum. 30. (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] S. Ohtsuka, I. Yamaguchi, J. Wu, T. Takeda, Y. Itai, A. Maruhashi, K. Hyodo and M. Ando: "Clinical application of synchrotron radiation to intravenous coronary angiography at PF-AR"Photon Factory Activity Report. 18. 43-44 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] K, Hyodo, H. Sugiyama and M. Ando: "Development of imaging system for medical and biological applications using monochromatic synchrotron radiation X-rays"Ionizing Radiation. 28(4) (in Japanese). 269-280 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] N.Nariyama, et al.: "Comparison of In-phantom Dose Distributions for Coronary Angiography Using an X-ray and"Medical Physics. 28(1). 16-21 (2001)

    • Related Report
      2002 Annual Research Report
  • [Publications] M.Ando, et al.: "A New Optics for Dark Field Imaging in X-Ray Region "Owl""JJAP. 40. L844-L848 (2001)

    • Related Report
      2002 Annual Research Report
  • [Publications] 兵藤一行, 他: "放射光単色X線を用いた造影剤の静脈注入による冠動脈診断システム"日本写真学会誌. 65(7). 490-494 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] K.Hyodo et al.: "Development of the two-dimensional intravenous coronary angiography system II at the PF-AR NE1, KEK"Proceedings of the 5th Harima International Forum Harima Conference. 30 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] M.Ando et al.: "X-ray optics Owl and Trinity"Jpn. J. Appl. phys.. (印刷中). (2002)

    • Related Report
      2001 Annual Research Report

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Published: 2001-04-01   Modified: 2016-04-21  

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