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Nosological and Diagnostic Study of Other Pervasive Developmental Disorders

Research Project

Project/Area Number 13670983
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Psychiatric science
Research InstitutionThe University of Tokyo

Principal Investigator

KURITA Hiroshi  The University of Tokyo, Graduate School of Medicine, Professor, 大学院・医学系研究科, 教授 (30010466)

Project Period (FY) 2001 – 2004
Project Status Completed (Fiscal Year 2004)
Budget Amount *help
¥3,200,000 (Direct Cost: ¥3,200,000)
Fiscal Year 2004: ¥700,000 (Direct Cost: ¥700,000)
Fiscal Year 2003: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 2002: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 2001: ¥1,500,000 (Direct Cost: ¥1,500,000)
Keywordsatypical autism / child psychiatry / head circumference / pervasive developmental disorder (PDD) / PDD not otherwise specified (PDDNOS) / pervasive developmental disorder(PDD) / PDP not otherwise specified(PDDNOS) / attention-deficit / hyperactivity disorder (ADHD) / diagnosis / pervasive developmental disorders (PDD) / intelligence scale / autistic disorder / Asperger's disorder / pervasive developmental disorders(PDD) / PDD not otherwise specified(PDDNOS)
Research Abstract

This study consists of 7 clinical studies on pervasive developmental disorder (PDD) not other wise specified (PDDNOS) or atypical autism (AA), which are the majority of PDD and many of which are high-functioning (IQ【greater than or equal】70).
Study I : Childhood Autism Rating Scale-Tokyo Version (CARS-TV) total score was compared between 430 PDD children and 75 children with mental retardation and no history of PDD (MR) and among 4 PDD subgroups (i.e., autistic disorder [AD], childhood disintegrative disorder [CDD], Asperger's disorder [ASD], PDDNOS). The total score was significantly higher in PDD than MR, AD and CDD than PDDNOS and ASD, and PDDNOS than ASD. Its cutoffs were 25.5/26 for PDD/MR and 30/30.5 for AD/PDDNOS.
Study II : Autism Spectrum Quotient Japanese Version (AQ-J) score had good reliability, was significantly higher in 15 male adolescents with high-functioning PDD (HPDD) than 49 controls, and its HPDD cutoff was 26.
Study III : When 53 high-functioning AA children and 21 h … More igh-functioning childhood autism children were compared on CARS-TV items with IQ and CARS TV total score controlled for, the former was significantly less abnormal in interpersonal relations and general impressions and significantly stronger in anxiety reaction.
Study IV : Head circumference was not significantly different among 143 AA, 95 CA and normative data in infants, while it was significantly larger in females than males in both AA and CA groups.
Study V : When IQ, gender and age matched (n=22) high-functioning PDDNOS patients and attention-deficit hyper-activity disorder patients were compared on WISC-R, the former was significantly more inferior in verbal IQ, verbal comprehension, vocabulary, comprehension, and more excellent in block design, coding and processing speed.
Study VI : In 19 AD, 59 PDDNOS, 24 MR without PDD history, in whom the Child Behavior Questionnaire-Revised (CBQ-R) was administered in 4 to 6 years and 24-36 months later, there was no transaction between diagnosis and time and there existed IQ increase and CBQ-R score decrease in the three groups.
Study VII : At average 20 years, 41 AA was significantly lower in the degree of autism and higher in the rate of high-functioning than 83 CA. Less

Report

(5 results)
  • 2004 Annual Research Report   Final Research Report Summary
  • 2003 Annual Research Report
  • 2002 Annual Research Report
  • 2001 Annual Research Report
  • Research Products

    (32 results)

All 2005 2004 2003 2002 2001 Other

All Journal Article (16 results) Book (1 results) Publications (15 results)

  • [Journal Article] 乳幼児期自閉症チェックリスト日本語版(CHAT-J)の有用性に関する予備的検討2005

    • Author(s)
      小山智典, 船曳幸紀, 長田洋和, 武田俊信, 志水かおる, 栗田広
    • Journal Title

      臨床精神医学 (印刷中)

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Cognitive and symptom profiles in high-functioning PDDNOS and attention-deficit/hyperactivity disorder2005

    • Author(s)
      Koyama T, Tachimori H, Osada H, Kurita H
    • Journal Title

      Journal of Autism and Developmental Disorders (in press)

    • Related Report
      2004 Annual Research Report
  • [Journal Article] 広汎性発達障害(PDD)児とPDD非合併精神遅滞児の経時的発達変化の比較2004

    • Author(s)
      井筒節, 加藤星花, 長田洋和, 栗田広
    • Journal Title

      臨床精神医学 33

      Pages: 65-69

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] A comparison of high-functioning atypical autism and childhood autism by Childhood Autism Rating Scale-Tokyo Version2004

    • Author(s)
      Kanai C, Koyama T, Kato S, Miyamoto Y, Osada H, Kurita H
    • Journal Title

      Psychiatry and Clinical Neurosciences 58

      Pages: 217-221

    • NAID

      10018368881

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] A comparative study of longitudinal development between children with pervasive developmental disorder (PDD) and children with mental retardation without PDD.2004

    • Author(s)
      Izutsu, T., Kato, S., Osada, H., Kurita, H.
    • Journal Title

      Japanese Journal of Clinical Psychiatry (in Japanese) 33

      Pages: 65-69

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] A comparison of high-functioning atypical autism and childhood autism by Childhood Autism Rating Scale-Tokyo Version.2004

    • Author(s)
      Kanai, C., Koyama, T., Kato, S., Miyamoto, Y., Osada, H., Kurita, H
    • Journal Title

      Psychiatry and Clinical Neurosciences 58

      Pages: 217-221

    • NAID

      10018368881

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] 自閉性スペクトル指数日本版(AQ-J)のアスペルガー障害に対するカットオフ2004

    • Author(s)
      栗田広, 長田洋和, 小山智典, 金井智恵子, 宮本有紀, 志水かおる
    • Journal Title

      臨床精神医学 33

      Pages: 209-214

    • NAID

      40006121397

    • Related Report
      2004 Annual Research Report
  • [Journal Article] 広汎性発達障害スクリーニング尺度としての乳幼児行動チェックリスト改訂版(IBC-R)の有用性の検討2004

    • Author(s)
      金井智恵子, 長田洋和, 小山智典, 栗田広
    • Journal Title

      臨床精神医学 33

      Pages: 313-321

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Childhood Autism Rating Scale-Tokyo Version for screening pervasive developmental disorders2003

    • Author(s)
      Tachimori H, Osada H, Kurita H
    • Journal Title

      Psychiatry and Clinical Neurosciences 57

      Pages: 113-118

    • NAID

      10018974778

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] 自閉性スペクトル指数日本版(AQ-J)の信頼性と妥当性2003

    • Author(s)
      栗田広, 長田洋和, 小山智典, 宮本有紀, 金井智恵子, 志水かおる
    • Journal Title

      臨床精神医学 32

      Pages: 1235-1240

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Childhood Autism Rating Scale-Tokyo Version for screening pervasive developmental disorders.2003

    • Author(s)
      Tachimori, H., Osada, H., Kurita, H.
    • Journal Title

      Psychiatry and Clinical Neurosciences 57

      Pages: 113-118

    • NAID

      10018974778

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Reliability and validity of the Autism-Spectrum Quotient Japanese Version (AQ-J).2003

    • Author(s)
      Kurita, H., Osada, H., Koyama, T., Miyamoto, Y., Kanai, C., Shimizu, K.
    • Journal Title

      Japanese Journal of Clinical Psychiatry (in Japanese) 32

      Pages: 1235-1240

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] 広汎性発達障害の診断補助尺度としての小児行動質問表改訂版(CBQ-R)の有用性に関する研究2001

    • Author(s)
      井筒節, 長田洋和, 立森久照, 長沼洋一, 加藤星花, 堤敦朗, 栗田広, 太田昌孝
    • Journal Title

      臨床精神医学 30

      Pages: 525-532

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] A study on the utility of the Child Behavior Questionnaire Revised (CBQ-R) as an adjunctive diagnostic scale of pervasive developmental disorders.2001

    • Author(s)
      Izutsu, T., Osada, H., Tachimori, H., Naganuma, Y., Kato, S., Tsutsumi, A., Kurita, H., Ohta, M.
    • Journal Title

      Japanese Journal of Clinical Psychiatry (in Japanese) 30

      Pages: 525-532

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Cognitive and symptom profiles in high-functioning PDDNOS and attention-deficit/hyperactivity disorder

    • Author(s)
      Koyama T, Tachimori H, Osada H, Kurita H
    • Journal Title

      Journal of Autism and Developmental Disorders (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Cognitive and symptom profiles in high-functioning pervasive developmental disorder not otherwise specified and attention-deficit/hyperactivity disorder.

    • Author(s)
      Koyama, T., Tachimori, H., Osada, H., Kurita, H.
    • Journal Title

      Journal of Autism and Developmental Disorders (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Book] 特定不能の広汎性発達障害.現代児童青年精神医学(山崎晃資,牛島定信,栗田広,青木省三編)2002

    • Author(s)
      栗田広
    • Publisher
      永井書店
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Publications] 小山智典, 立森久照, 長田洋和, 戸張美佳, 石田博美, 栗田広: "WISC-IIIによる高機能広汎性発達障害と注意欠陥/多動性障害の認知プロフィールの比較"精神医学. 45. 809-815 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 小山智典, 長田洋和, 立森久照, 戸張美佳, 志水かおる, 武田俊信, 栗田広: "広汎性発達障害児の発達評価における発達指数(DQ)の臨床的意義"臨床精神医学. 32. 1081-1087 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 栗田広, 長田洋和, 小山智典, 宮本有紀, 金井智恵子, 志水かおる: "自閉性スペクトル指数日本版(AQ-J)の信頼性と妥当性"臨床精神医学. 32. 1235-1240 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 志水かおる, 長田洋和, 中野知子, 渡辺友香, 栗田広: "広汎性発達障害(PDD)と注意欠陥/多動性障害(AD/HD)における人物画描画能力の比較"精神医学. 45. 1305-1311 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 井筒節, 加藤星花, 長田洋和, 栗田広: "広汎性発達障害(PDD)児とPDD非合併精神遅滞児の経時的発達変化の比較"臨床精神医学. 33. 65-69 (2004)

    • Related Report
      2003 Annual Research Report
  • [Publications] Kanai, C., Koyama, T., Kato, S., Miyamoto, Y., Osada, H., Kurita, H: "A comparison of high-functioning atypical autism and childhood autism by Childhood Autism Rating Scale-Tokyo Version"Psychiatry and Clinical Neurosciences. (in press).

    • Related Report
      2003 Annual Research Report
  • [Publications] 渡辺友香, 長沼洋一, 瀬戸屋雄太郎, 長田洋和, 立森久照, 久保田友子, 栗田広: "広汎性発達障害(PDD)児および精神遅滞児における人物画描画能力の比較研究"精神医学. 44. 391-399 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Tachimori, H., Osada, H., Kurita, H.: "Childhood Autism Rating Scale--Tokyo Version for screening pervasive developmental disorders"Psychiatry and Clinical Neurosciences. 57. 113-118 (2003)

    • Related Report
      2002 Annual Research Report
  • [Publications] Kurita, H., Osada, H., Shimizu, K., Tachimori, H.: "Validity of DQ as an estimate of IQ in children with autistic disorder"Psychiatry and Clinical Neurosciences. 57. 233-235 (2003)

    • Related Report
      2002 Annual Research Report
  • [Publications] 大塚麻揚, 立森久照, 長田洋和, 瀬戸屋雄太郎, 中野知子, 栗田広: "高機能広汎性発達障害と注意欠陥/多動性障害の知的能力と自閉症状からみた異同"精神医学. 45. 175-181 (2003)

    • Related Report
      2002 Annual Research Report
  • [Publications] Thomsen, P.H., Kurita, H.: "International perspective. In. Martin, A., Scahill, L., Charney, D.S.and Leckman, J.F.(ed.) : Pediatric Psychopharmacology : Principles and Practice"Oxford University Press. 746-755 (2003)

    • Related Report
      2002 Annual Research Report
  • [Publications] 井筒節, 長田洋和, 立森久照, 長沼洋一, 加藤星花, 堤敦朗, 栗田広, 太田昌孝: "広汎性発達障害の診断補助尺度としての小児行動質問表改訂版(CBQ-R)の有用性に関する研究"臨床精神医学. 30. 525-532 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] 栗田広: "広汎性発達障害"小児科. 42. 1927-1932 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] 長田洋和, 浦田泰平, 立森久照, 長沼洋一, 栗田広: "東京小児発達スケジュール(TCDS)の広汎性発達障害の鑑別尺度としての有用性の検討"臨床精神医学. 31. 191-197 (2002)

    • Related Report
      2001 Annual Research Report
  • [Publications] 栗田広, 立森久照, 長田洋和: "AD/HDと高機能PDD"精神科治療学. 17. 149-154 (2002)

    • Related Report
      2001 Annual Research Report

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Published: 2001-04-01   Modified: 2016-04-21  

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