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Realization of Real-Time MR Image Guided Surgery Combined with High-Resolution 3D Image Navigation

Research Project

Project/Area Number 13671227
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field General surgery
Research InstitutionSHIGA UNIVERSITY OF MEDICAL SCIENCE

Principal Investigator

MORIKAWA Shigehiro  SHIGA UNIV.MED.SCI., MOL.NEUROSCI.RES.CTR.ASSOCIATE PROFESSOR, 分子神経科学研究センター, 助教授 (60220042)

Co-Investigator(Kenkyū-buntansha) KURUMI Yoshimasa  SHIGA UNIV.MED.SCI., DEPT.OF MEDICINE, LECTURER, 医学部, 講師 (70205219)
SHIINO Akihiko  SHIGA UNIV.MED.SCI., DEPT.OF MEDICINE, LECTURER, 医学部, 講師 (50215935)
INUBUSHI Toshiro  SHIGA UNIV.MED.SCI., MOL.NEUROSCI.RES.CTR.PROFESSOR, 分子神経科学研究センター, 教授 (20213142)
HATA Nobuhiko  THE UNIVERSITY OF TOKYO GRADUATE SCHOOL OF INFORMATION SCIENCE & TECHNOLOGY, LECTURER, 大学院・情報理工学系, 講師 (50334256)
HAQUE Hasnine a  GE-YOKOGAWA MEDICAL SYSTEMS, ADVANCED TECHNOLOGY CENTER SENIOR SCIENTIST, 技術開発センター, 研究員
HASNINE A Haque  GE横河メディカルシステム技術開発センター, 研究員
VISWANATHAN Seshan  GE横河メディカル, 技術部・研究員
Project Period (FY) 2001 – 2002
Project Status Completed (Fiscal Year 2002)
Budget Amount *help
¥3,000,000 (Direct Cost: ¥3,000,000)
Fiscal Year 2002: ¥1,000,000 (Direct Cost: ¥1,000,000)
Fiscal Year 2001: ¥2,000,000 (Direct Cost: ¥2,000,000)
KeywordsMR-guided surgery / minimally invasive surgery / computer-assisted surgery / Thermal therapy / MR temperature map
Research Abstract

Real-time MR images, which are acquired every 2-3 seconds, are quite useful for image-guided surgery, but their image resolution and contrast are not always satisfactory because of the limited acquisition time. We planed to combine high resolution preoperative 3D image data with real-time MR images for surgical navigation. First, we prepared a program on the MR system to send acquired real time images and the information, of the hand-piece position for image plane control continuously. Navigation software, 3D Slicer, was obtained from Harvard, was installed in an independent computer and was customized for our purpose, We could successfully reconstruct reformatted images in the same and perpendicular planes as the real-time MR images from preoperative 3D image data and send these images to the surgeons inside immediately. Although the needle position had to be recognized in the real-time images, the reformatted images showed the target more clearly than the real-time. This system has already been used in 50 cases of microwave ablation for liver tumors and 10 neurosurgical cases. The reformatted images could also show the surrounding structures of the target, such as large vessels, and made the procedure safer. For the real-time MR images, Tl-weighted images are usually used, but any images with different contrasts, such as T2-weighte images or Gd-enhanced images could be combined as the preoperative 3D volume data. In the microwave thermocoagulation therapy of liver tumors, punctures and ablations are repeated many times. We added "FootPrinting" function in this software in order to record the individual football-shaped coagulation areas in the 3D space. This function made the procedure more accurate and easy. This system is now used in all the procedures.

Report

(3 results)
  • 2002 Annual Research Report   Final Research Report Summary
  • 2001 Annual Research Report
  • Research Products

    (32 results)

All Other

All Publications (32 results)

  • [Publications] Morikawa S, Inubushi T, et al.: "Feasibility of Microwave ablation for MR-guided interstitial thermal therapy : an experimental study using 2T MR system"日本磁気共鳴学会雑誌. 21. 79-84 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] 森川茂廣, 犬伏俊郎, 他: "リアルタイムMR撮像ナビゲーション装置用補助器具の開発"日本磁気共鳴学会雑誌. 21. 193-197 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Morikawa S, Inubushi T, et al.: "MR-Guided Microwave Thermocoagulation Therapy of Liver Tumors : Initial Clinical Experiences Using a 0.5 T Open MR System"J Magn Reson Imaging. 16. 576-583 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] 森川茂廣, 犬伏俊郎, 他: "リアルタイムMR画像ガイド下手術へのカスタマイズしたナビゲーションソフトウェアの統合"日本コンピュータ外科学会誌. 4. 27-33 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Morikawa S, Inubushi T, et al.: "New assistive devices for MR-guided microwave thermocoagulation of liver tumors"Acad Radiol. 10. 180-188 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] 森川茂廣, 犬伏俊郎, 他: "リフルタイムMR画像ガイドにおけるオフセット型穿刺補助器具の開発"日本コンピュータ外科学会誌. (印刷中).

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Morikawa S, Inubushi T, et al.: "Lecture Notes in Computer Science 2489、Technical developments for MR-guided microwave thermocoagulation therapy of liver tumors"Splinger. 8 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Morikawa S, Inubushi T, Kurumi Y, Naka S: "Feasibility of Microwave ablation for MR-guided interstitial thermal therapy : an experimental study using 2T MR system"Jpn J Magn Reson Med. 21. 79-84 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Morikawa S, Inubushi T: "Fast ^<13>C-glucose metabolite mapping in rat brain using ^1H echo planar spectroscopic technique at 2T"J Magn Reson Imaging. 13. 787-791 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Suzuki E, Kashiwagi A, Nishio Y, Egawa K, Shimaizu S, Maegawa H, Haneda M, Yasuda H, Morikawa S, Inubushi T, Kikkawa R: "Increased arterial wall stiffness limits flow volume in the lower extremities in type 2 diabetic patients"Diabetes Care. 24. 2107-2114 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Yamamoto D, Tanaka K, Nakai K, Baden T, Inoue K, Yamamoto C, Takemoto H, Kamato K, Hirata H, Morikawa S, Inubushi T, Hioki K: "Synergistic effects induced by cycloprodigiosyn hydrochloride and epirubicin on human breast cancer cells"Breast Cancer Res Tr. 72. 1-10 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Mukaisho K, Kurumi Y, Sugihara H, Naka S, Kamitani S, Tsubosa Y, Moritani S, Endo Y, Hanasawa K, Morikawa S, Inubushi T, Hattori T, Tani T: "Enzyme histochemistry is useful to assess viability of tumor tissue after microwave coagulation therapy (MCT) : Metastatic adenocarcinoma treated by lateral segmentectomy after MCT"Dig Dis Sci. 11. 2441-2445 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Morikawa S, Inubushi T, Kurumi Y, Naka S, Sato K, Tani T, Yamamoto I, Fujimura M: "MR-Guided Microwave Thermocoagulation Therapy of Liver Tumors : Initial Clinical Experiences Using a 0.5 T Open MR System"J Magn Reson Imaging. 16. 576-583 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Morikawa S, Inubushi T, Kurumi Y, Naka S, Sato K, Tani T, Hata N, Seshan V, Haque HA: "Technical developments for MR-guided microwave thermocoagulation therapy of liver tumors"Splinger, Lecture Notes in Computer Science. 2489. 52-59 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Hata N, Tokuda J, Morikawa S, Dohi T: "Projection profile matching for intraoperative MRI registration embedded in MR imaging sequence"Splinger, Lecture Notes in Computer Science. 2489. 164-169 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Ishii H, Arai T, Segawa H, Morikawa S, Inubushi T, Fukuda K: "Effects of propofol on lactate accumulation and oedema formation in focal cerebral ischaemia in hyperglycaemic rats"Brit J Anaesth. 88. 412-417 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Sawada T, Nakamura J, Nishida Y, Kani K, Morikawa S, Inubushi T: "Magnetic resonance studies of the volume of the rabbit eye with intravenous mannitol"Curr Eye Res. 25. 173-177 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Morikawa S, Inubushi T, Kurumi Y, Naka S, Sato K, Tani T, Haque HA, Tokuda J, Hata N: "New assistive devices for MR-guided microwave thermocoagulation of liver tumors"Acad Radiol. 10. 180-188 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Shiino A, Matsuda M, Morikawa S: "Overheating of Midas Rex MRIV motor by induced current"Neurosurgery. 52. 479 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Suzuki E, Egawa K, Nishio Y, Maegawa H, Tsuchiya M, Haneda M, Yasuda H, Morikawa S, Inubushi T, Kashiwagi A: "Prevalence and major risk factors of reduced flow volume in lower extremities with normal ankle-brachial index in Japanese patients with type 2 diabetes mellitus"Diabetes Care. (in press).

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Morikawa S, Inubushi T, Kurumi Y, et al.: "MR-guided microwave thermocoagulation therapy of liver tumors: initial clinical experiences using a 0.5T open MR system."Journal of Magnetic Resonance Imaging. 16. 576-583 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Morikawa S, Inubushi T, Kurumi Y et al.: "New assistive devices for MR-guided microwave thermocoagulation of liver tumors."Academic Radiology. 10. 180-188 (2003)

    • Related Report
      2002 Annual Research Report
  • [Publications] 森川茂廣, 犬伏俊郎, 他: "リアルタイムMR画像ガイド下手術へのカスタマイズしたナビゲーションソフトウェアの統合"日本コンピュータ外科学会誌. 4. 27-33 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] 森川茂廣, 犬伏俊郎, 他: "リアルタイムMR画像ガイドにおけるオフセット型穿刺補助器具の開発"日本コンピュータ外科学会誌. (印刷中).

    • Related Report
      2002 Annual Research Report
  • [Publications] 森川茂廣, 犬伏俊郎, 他: "マイクロ波出力と針状電極の形状による加温領域への影響-画像を用いた連続的モニタリング-"J Microwave Surg. 20. 27-33 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] 谷徹, 来見良誠, 森川茂廣: "腹部外科とナビゲーションサージャリー"手術. 56. 1451-1460 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Morikawa S, Inubushi T, et al.: "Technical developments for MR-guided microwave thermocoagulation therapy of liver tumors. In : Lecture Notes in Computer Science 2489"Splinger.. 52-59(8) (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] 森川茂廣, 犬伏俊郎, 他: "MR対応内視鏡システムの構築とその臨床応用"日本磁気共鳴学会誌. 21. 155-160 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] 森川茂廣, 犬伏俊郎, 他: "リアルタイムMR撮像ナビゲーション装置用補助器具の開発"日本磁気共鳴学会誌. 21. 193-197 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] 来見良誠, 仲成幸, 他: "垂直型オープンMR装置を用いたMRガイド下肝腫瘍治療"日本磁気共鳴学会誌. 21. 170-180 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] 山本育男, 藤村昌樹, 他: "IVRの現状と問題点:Interventional MRI"臨床外科. 56. 1637-1646 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] 森川茂廣, 犬伏俊郎, 他: "MRガイド下microwave surgeryにおけるノイズの問題とその対策"J Microwave Surg. 19. 35-38 (2001)

    • Related Report
      2001 Annual Research Report

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Published: 2001-04-01   Modified: 2016-04-21  

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