• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Intraoperative evaluation for preservation of erectile and bladder function using functional anatomical method

Research Project

Project/Area Number 13671634
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Urology
Research InstitutionGunma University

Principal Investigator

KUROKAWA Kohei  Gunma University, School of Medicine, Assistant Professor, 医学部, 講師 (50225281)

Co-Investigator(Kenkyū-buntansha) YAMANAKA Hidetoshi  Gunma University, School of Medicine, Professor emeritus, 医学部, 教授 (70110393)
SUZUKI Kazuhiro  Gunma University, School of Medicine, Associates Professor, 医学部, 助教授 (80312891)
FUKABORI Yoshitatsu  Gunma University, School of Medicine, Assistant Professor, 医学部, 講師 (90199167)
Project Period (FY) 2001 – 2003
Project Status Completed (Fiscal Year 2003)
Budget Amount *help
¥4,000,000 (Direct Cost: ¥4,000,000)
Fiscal Year 2003: ¥800,000 (Direct Cost: ¥800,000)
Fiscal Year 2002: ¥800,000 (Direct Cost: ¥800,000)
Fiscal Year 2001: ¥2,400,000 (Direct Cost: ¥2,400,000)
Keywordsmalignant tumors in pelvic organ / preservation of bladder function / preservation of erectile function / evaluation of preservation / preservation of ejaculation / functional anatomical method / 機能温存 / 陰茎海綿体内圧 / 膀胱内圧
Research Abstract

The clinical trial began in January, 2001 under the permission of our IRB. Fifty cases who had undergone radical surgery for intrapelvic malignancy and wanted to preserve bladder function and/or erectile function were enrolled in this trial until January 2004. Three cases had urologic malignancy, 28 (22 s, 6 females) had rectal cancer, and the remaining 19 cases had uterine cervical cancer.
Thirty-eight completed postoperative follow-up periods. The over all accuracy of intraoperative evaluation for the preservation of erectile or bladder function was 82.3% (28/34), and 4 cases were excluded due to disease progression.
Though our system predicted postoperative erectile or bladder function exactly, using our system did not enhance the preservation rate of postoperative pelvic function. To improve our system, we developed a new stimulation electrode. Using this electrode, the Operator could perform both bipolar and monopolar stimulation alternately, which enabled obscure or fine stimulation. In gynecological cases, this device was accepted affirmatively and cases were collected actively.
We also developed the prototype equipment for our system, which had a low price and was easy to handle. After an evaluation of the equipment using an animal model, we plan to evaluate its usefulness clinically.

Report

(4 results)
  • 2003 Annual Research Report   Final Research Report Summary
  • 2002 Annual Research Report
  • 2001 Annual Research Report

Research Products

(47 results)

All Other

All Publications (47 results)

  • [Publications] Kurokawa K.: "Usefulness of PSA screening in outpatients with bladder cancer : Preliminary results."Int J Urol. 9. 237-240 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Kurokawa K.: "Salvage external beam radiotherapy for local recurrence without systemic progression or prostate specific antigen recurrence of prostate cancer after initial hormonal therapy : Is it possible to identify patients likely to have good treatment outcomes?"Jpn J Ciln Oncol. 32. 466-471 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] 黒川公平: "機能的解剖を応用した術中勃起神経温存評価の短期結果"泌尿器外科. 15. 928-930 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] 黒川公平: "特集 私の行っている縫合と吻合の手技3 膀胱・尿道吻合"臨床泌尿器科. 56. 1119-1123 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] 黒川公平: "前立腺癌 病気と治療法の適応と成績"ホルモンと臨床. 50. 89-96 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] 黒川公平: "前立腺癌集団検診における年齢階層別PSA基準値の有用性"日本腎泌尿器疾患予防医学研究会誌. 9. 18-19 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] 黒川公平: "前立腺肥大症"腎疾患最新の治療. 198-200 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] 黒川公平: "尿路腫瘍(膀胱、腎盂・尿管癌)外来におけるPSAスクリーニング"日本腎泌尿器疾患予防医学研究会誌. 10. 29-30 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Kurokawa K.: "Preliminary results of a monitoring system to confirm the preservation of the cavernous nerves."Int J Urol. 10. 136-140 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Kurokawa K.: "Usefulness of PSA screening in outpatients with bladder cancer"Int.J.Urol.. 9. 237-240 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Kurokawa K.: "Salvage external beam radiotherapy for local recurrence without systemic progression or prostate specific antigen recurrence of prostate cancer after initial hormonal therapy : Is it possible to identify patients likely to have good treatment outcomes?"Jpn J Clin Oncol. 32. 466-471 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Kurokawa K.: "Preliminary results of a monitoring system to confirm the preservation of the cavernous nerves."Int J Urol. 10. 136-140 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Kurokawa K.: "Comparative study on the prevalence of clinically detectable prostate cancer in patients with and without bladder cancer."Urology. 63. 268-272 (2004)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Kaiho Y, Kurokawa K.et al.: "Electrostimulation of sympathetic nerve fibers during nerve-sparing laparoscopic retroperitoneal lymph node dissection in testicular tumor."Int J Urol. 10. 284-286 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Terada N., Kurokawa K.et al.: "Intraoperative electrical stimulation of cavernous nerves with monitoring of intracorporeal pressure to confirm nerve sparing during radical prostatectomy : clinical results."Int J Urol. 10. 251-256 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] 黒川公平, 山中英壽 31(2) : 183-187(2001): "特集:排尿障害へのアプローチ頻尿の考え方"臨床成人病. 31(2). 183-187 (2001)

    • Related Report
      2003 Annual Research Report
  • [Publications] 黒川公平: "初回ホルモン療法後の再燃における放射線療法の適応-PSA DOUBLING TIME(PSADT)による判定は可能か"泌尿器外科. 14. 451-453 (2001)

    • Related Report
      2003 Annual Research Report
  • [Publications] 黒川公平: "外来における排尿障害の診断"産婦人科治療. 83. 552-559 (2001)

    • Related Report
      2003 Annual Research Report
  • [Publications] 黒川公平, 伊藤一人, 山中英壽: "前立腺生検の動向について"実験治療. 664. 170-173 (2001)

    • Related Report
      2003 Annual Research Report
  • [Publications] 黒川公平: "外来における排尿障害の診断"産婦人科治療. 83. 552-559 (2001)

    • Related Report
      2003 Annual Research Report
  • [Publications] K.Kurokawa: "Usefulness of PSA screening in outpatients with bladder cancer : Preliminary results."Int.J.Urol.. 9. 237-240 (2002)

    • Related Report
      2003 Annual Research Report
  • [Publications] K.Kurokawa: "Salvage external beam radiotherapy for local recurrence without systemic progression or prostate specific antigen recurrence of prostate cancer after initial hormonal therapy : Is it possible to identify patients likely to have good treatment outcomes?"Jpn.J.Ciln.Oncol.. 32. 466-471 (2002)

    • Related Report
      2003 Annual Research Report
  • [Publications] 黒川公平: "機能的解剖を応用した術中勃起神経温存評価の短期結果"泌尿器外科. 15. 928-930 (2002)

    • Related Report
      2003 Annual Research Report
  • [Publications] 黒川公平: "特集 私の行っている縫合と吻合の手技3 膀胱・尿道吻合"臨床泌尿器科. 56. 1119-1123 (2002)

    • Related Report
      2003 Annual Research Report
  • [Publications] 黒川公平: "前立腺癌 病期と治療法の適応と成績"ホルモンと臨床. 50. 89-96 (2002)

    • Related Report
      2003 Annual Research Report
  • [Publications] 黒川公平: "前立腺癌集団検診における年齢階層別PSA基準値の有用性"日本腎泌尿器疾患予防医学研究会誌. 9. 18-19 (2002)

    • Related Report
      2003 Annual Research Report
  • [Publications] 黒川公平: "尿路腫瘍(膀胱、腎孟・尿管癌)外来におけるPSAスクリーニング"日本腎泌尿器疾患予防医学研究会誌. 10. 29-30 (2002)

    • Related Report
      2003 Annual Research Report
  • [Publications] 黒川公平: "前立腺癌をめぐるコンセンサスと論点-局所伸展症例に対する治療戦略"癌と化学療法. 30. 38-42 (2002)

    • Related Report
      2003 Annual Research Report
  • [Publications] K.Kurokawa: "Preliminary results of a monitoring system to confirm the preservation of the cavernous nerves."Int.J.Urol.. 10. 136-140 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] K.Kurokawa: "Comparative study on the prevalence of clinically detectable prostate cancer in cases with and without bladder cancer."Urology. 63. 268-272 (2004)

    • Related Report
      2003 Annual Research Report
  • [Publications] 黒川公平, 鈴木和浩, 山中英壽: "骨盤内神経温存確認装置の開発とその応用:勃起神経、排尿を司る神経の温存と射精神経温存"泌尿器外科. 16. 661-670 (2004)

    • Related Report
      2003 Annual Research Report
  • [Publications] Y.asuhiro Kaiho, Haruo Nakagawa, Akira Takeuchi, Akihito Ito, Makoto Satoh, Kohei Kurokawa, Yoichi Arai: "Electrostimulation of sympathetic nerve fibers during nerve-sparing laparoscopic retroperitoneal lymph node dissection in testicular tumor."Int.J.Urol.. 10. 284-286 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] Naoki Terada, Yoichi Arai, Kohei Kurokawa, Hiroki Ohara, Kenataro Ichioka, Yoshiyuki Matui, Koji Yoshimura, Hidetoshi Yamanaka, Akito Terai: "Intraoperative electrical stimulation of cavernous nerves with monitoring of intracorporeal pressure to confirm nerve sparing during radical prostatectomy : Early cilnical results"Int.J.Urol.. 10. 251-256 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 黒川公平: "腎疾患最新の治療"南江堂. 380 (2002)

    • Related Report
      2003 Annual Research Report
  • [Publications] 黒川公平, 伊藤一人, 鈴木和浩: "泌尿器科疾患の最新医療"先端医療技術研究所. 534 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 黒川公平, 内田好司, 山中英壽: "うんちとおしっこの話"上毛新聞社. 260 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] Kurokawa K.: "Usefulness of PSA screening in outpatients with bladder cancer : Preliminary results"Int J Urol. 9. 237-240 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Kurokawa K.: "Salvage external beam radiotherapy for local recurrence without systemic progression or prostate specific antigen recurrence of prostate cancer after initial hormonal therapy : Is it possible to identify patients likely to have good treatment outcomes?"Jpn J Clin Oncol. 32. 466-471 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] 黒川公平: "機能的解剖を応用した術中勃起神経温存評価の短期結果"泌尿器外科. 15. 928-930 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] 黒川公平: "特集 私の行っている縫合と吻合の手技3 膀胱・尿道吻合"臨床泌尿器科. 56. 1119-1123 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] 黒川公平: "前立腺癌 病気と治療法の適応と成績"ホルモンと臨床. 50. 89-96 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] 黒川公平: "前立腺癌集団検診における年齢階層別PSA基準値の有用性"日本腎泌尿器疾患予防医学研究会誌. 9. 18-19 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] 黒川公平: "尿路腫瘍(膀胱、腎孟・尿管癌)外来におけるPSAスクリーニング"日本腎泌尿器疾患予防医学研究会誌. 10. 29-30 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] 黒川公平: "前立腺癌をめぐるコンセンサスと論点・局所伸展症例に対する治療戦略"癌と化学療法. 30. 38-42 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Kurokawa K.: "Preliminary results of a monitoring system to confirm the preservation of the cavernous nerves"Int J Urol. 10. 136-140 (2003)

    • Related Report
      2002 Annual Research Report
  • [Publications] 黒川公平: "腎疾患最新の治療"前立腺肥大症. 198-200 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] KOHEI KUROKAWA, TAKANORI SUZUKI, KAZUHIRO SUZUKI, KAZUTO ITO, NOBUAKI SHIMIZU, YOSHITATSU FUKABORI, HIDETOSHI YAMANAKA: "SIMPLE AND RELIABLE MONITORING SYSTEM TO CONFIRM THE PRESERVATION OF THE CAVERNOUS NERVES"Int.J.Urol. 8・5. 231-236 (2001)

    • Related Report
      2001 Annual Research Report

URL: 

Published: 2001-03-31   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi