| Project/Area Number |
13671767
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Otorhinolaryngology
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| Research Institution | The University of Tokyo |
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Principal Investigator |
TAKAI Yoshinari (2003-2004) The University of Tokyo, Faculty of Medicine, Assistant, 医学部附属病院, 助手 (50345211)
室伏 利久 (2001-2002) 東京大学, 医学部附属病院, 講師 (30242176)
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| Co-Investigator(Kenkyū-buntansha) |
IWASAKI Shin-ichi The University of Tokyo, Faculty of Medicine, Assistant, 医学部附属病院, 助手 (10359606)
USHIO Munetaka The University of Tokyo, Faculty of Medicine, Assistant, 医学部附属病院, 助手 (70361483)
TAKAHIRO Asakage The University of Tokyo, Faculty of Medicine, Lecturer, 医学部附属病院, 講師 (50361481)
竹内 直信 東京大学, 医学部附属病院, 講師 (40280945)
物部 寛子 東京大学, 医学部附属病院, 助手 (90334375)
高井 禎成 東京大学, 医学部附属病院, 助手 (50345211)
松崎 真樹 東京大学, 保険センター, 助手 (80302701)
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| Project Period (FY) |
2001 – 2004
|
| Project Status |
Completed (Fiscal Year 2004)
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| Budget Amount *help |
¥3,700,000 (Direct Cost: ¥3,700,000)
Fiscal Year 2004: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 2003: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 2002: ¥600,000 (Direct Cost: ¥600,000)
Fiscal Year 2001: ¥2,100,000 (Direct Cost: ¥2,100,000)
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| Keywords | galvanic stimulation / vestibular nerve / saccular macula / neur ophysiology / evoked potential / VEMP / otolith organ / 球形のう / 前庭 / メニエール病 / 聴神経腫瘍 |
|---|
| Research Abstract |
We performed physiological studies concerning responses of vestibular afferents to short duration extracranial galvanic stimulation in guinea pigs and humans. In guinea pigs, some primary vestibular afferents responded to short duration extracranial galvanic stimulation. In human, short duration extracranial galvanic stimulation caused responses on the sternocleidomastoid mascle. The threshold of this response was 2.5mA and 5Hz was the optimal stimulation rate. Clinical studies suggested that this response is of vstibular origin. And, it was revealed that this response is useful for the differential diagnosis of the nerve lesion from the endrorgan lesion.
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