| Project/Area Number |
13671788
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Kumamoto University |
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Principal Investigator |
SAMEJIMA Yasuhiro University Hospital, Otolaryngology, Assistant Professor, 医学部附属病院, 講師 (50206009)
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| Co-Investigator(Kenkyū-buntansha) |
YUMOTO Eiji School of Medicine, Otolaryngology, Professor, 医学部, 教授 (40116992)
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| Project Period (FY) |
2001 – 2002
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| Project Status |
Completed (Fiscal Year 2002)
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| Budget Amount *help |
¥3,700,000 (Direct Cost: ¥3,700,000)
Fiscal Year 2002: ¥400,000 (Direct Cost: ¥400,000)
Fiscal Year 2001: ¥3,300,000 (Direct Cost: ¥3,300,000)
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| Keywords | head and neck cancer / swallowing / swallowing pressure / videofluoroscopy |
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| Research Abstract |
Post-operative swallowing function in the head and neck cancer was investigated by videofluoroscopy and manometric methods, to resolve the mechanism of dysphagia in such patients.
Objects were patients of oral cancer who were received lateral tongue rejection including the base tongue and those of pharyngeal cancer who were rejected half of soft palate and pharyngeal wall, each of them were reserved larynx.
Manometric study was performed by station pull-through methods, in which a pressure transducer probe was being withdrawn at each 1 cm step from a segment 25 to 8 cm from the nostril, and swallowing function was analyzed by a swallowing pressure curve showing peak values at each level and relaxation at the upper esophageal sphincter.
Videofluoroscopy revealed oral phase dysfunction in oral transit or lingual propulsion of the bolus (95%) and spillage to pharynx (59%), whereas pharyngeal dysfunction that is Barium residue (74%) and penetration or aspiration after swallow (47%).
Manometric study revealed normal relaxation at the upper esophageal sphincter, whereas low pressure at velopharyngeal and hypopharyngeal region.
These indicates dysphagia in post-operative patients of head and neck cancer was due to low pharyngeal pressure and large volume of flap to narrow pharyngeal space was needed to improve this dysfunction.
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