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THE RELATLONSHIP BETWEEN THE CLINICAL CONDETION AND THE MICROCIRCULATION OF PERIODONTAL TISSUES.

Research Project

Project/Area Number 13671908
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Morphological basic dentistry
Research InstitutionIWATE MEDICAL UNIVERSITY

Principal Investigator

NOZAKA Yohichiro  IWATE MEDICAL UNIV., PERT. ORAL ANATOMY, PROFESSOR, 歯学部, 教授 (60048379)

Co-Investigator(Kenkyū-buntansha) ONODERA Masao  IWATE MEDICAL UNIVERSITY, RESEACH FRLLOW, 歯学部, 助手 (10326689)
OSAWA Tokuji  IWATE MEDICAL UNIVERSITY, LECTURER, 歯学部, 講師 (00103747)
FUJIMURA Akira  IWATE MEDICAL UNIVERSITY, SUBPREF., 歯学部, 助教授 (80173459)
NARA Eisaku  IWATE MEDICAL UNIVERSITY, RESEACH FELLOW, 歯学部, 助手 (10275571)
Project Period (FY) 2001 – 2003
Project Status Completed (Fiscal Year 2003)
Budget Amount *help
¥1,400,000 (Direct Cost: ¥1,400,000)
Fiscal Year 2003: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 2002: ¥900,000 (Direct Cost: ¥900,000)
Keywordsperiodontal tissue / microcirculation / vascular architecture / basement membrane / laser speckle blood flow mater / vascular permeability / 歯周疾患 / 血流測定 / レーザードプラー
Research Abstract

Gingival Vascular architecture constitutes a simple capillary network beneath the sulcal epithelium and loops underlining the attached epithelium. These loops are 1045 4u m in diameter and formed heir pin under normal condition. But these loop and meshwork formed twisted loops and enlarged the diameter of capillary. Evaluation of microcirculation by cross-correlation between laser speckle signal and pulse( correlation coefficient 0.6 -0.8). The averages of frequency are 4000Hz in arterial blood flow and 300Hz in vein blood flow. When microcirculation was measured, sensor was fixed on gingival by using the stent and avoided to direct contact with gingival. The blood flow of gingival was shown that this blood flow meter was useful for the meaning of the objectivity in the clinical treatment.

Report

(4 results)
  • 2003 Annual Research Report   Final Research Report Summary
  • 2002 Annual Research Report
  • 2001 Annual Research Report
  • Research Products

    (32 results)

All Other

All Publications (32 results)

  • [Publications] 野坂洋一郎: "Changes of blood flow in pressure side of periodontal ligament during tooth Movement."Micrcirculation Annual 2003. 19・1. 85-86 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] 藤村 朗: "Three dimensional architecture of lymphatic vessels in the tongue.-"Lymphology. 38・4. 120-127 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] 藤村 朗: "Three-dimensional changes in lymphatic architecture around VX2 tongue cancer. -dynamicus of growth of cancer-"Lymphology. 36・4. 128-139 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] 大澤 得二: "Regeneration of the epidermis and mucosal epithelium on the basement membranes."Medical Electron Microscopy. 36・4. 193-203 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] 大澤 得二: "Scanning electron microscopic observation of the basement membranes with dithiothreitol separation"Medical Electron Microscopy. 36・3. 132-138 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] 藤村 朗: "圧迫側歯根膜の血流変化について"岩手医科大学歯学雑誌. 29・1. 1-9 (2004)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] 野坂洋一郎: "Nd : YAG 歯科用Nd : YAGレーザーの臨床応用"クインテッセンス出版. 250 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Yohichiro Nozaka: "Changes of blood flow in pressure side of periodontal ligament during tooth"Movement. 19・1. 85-86 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Akira Fujimura: "Three dimensional architecture of lymphatic vessels in the tongue.-"Lymphotogy.. 38・4. 120-127 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Akira Fujimura: "Three-dimensional changes in lymphatic architecture around VX2 tongue cancer. -dynamicus of growth of cancer -"Lymphology. 36・4. 128-139 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Tokui Osawa: "Regeneration of the epidermis and mucosal epithelium on the basement membranes."Medical Electron Microscopy. 36・4. 193-203 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Tokui Osawa: "Scanning electron microscopic observation of the basement membranes with dithiothreitol separation"Medical Electron Microscopy. 36・3. 132-138 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Akira Fujimura: "Changes of blood flow in pressure side of periodontal ligament during tooth movement."Dent.J.Iwate Med.Univ.. 29. 1-9 (2004)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Yohichiro Nozaka: "Assessment of effects of topical warming toothpaste on gingivitis using clinical indices of gingival index, bleeding on probing and plaque scoring system."J.Periodontal Res.. (In press).

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] 野坂洋一郎: "Changes of blood flow in pressure side of periodontal ligament during tooth Movement."Micrcirculation Annual 2003. 19・1. 85-86 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 藤村 朗: "Three dimensional architecture of lymphatic vessels in the tongue. -"Lymphology. 38・4. 120-127 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 藤村朗: "Three-dimensional changes in lymphatic architecture around VX2 tongue cancer. - dynamicus of growth of cancer -"Lymphology. 36・4. 128-139 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 大澤 得二: "Regeneration of the epidermis and mucosal epithelium on the basement membranes."Medical Electron Microscopy. 36・4. 193-203 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 大澤 得二: "Scanning electron microscopic observation of the basement membranes with dithiothreitol separation"Medical Electron Microscopy. 36・3. 132-138 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 藤村 朗: "圧迫側歯根膜の血流変化について"岩手医科大学歯学雑誌. 29・1. 1-9 (2004)

    • Related Report
      2003 Annual Research Report
  • [Publications] 野坂洋一郎: "Nd:YAG 歯科用Nd:YAGレーザーの臨床応用"クインテッセンス出版. 250 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 野坂洋一郎: "Angiogenesis and microcirculation of a autogenous gingival graft"Microcirculation Annual 2002. 18・1. 73-74 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] 藤村 朗: "Clinical evaluation of gingivitis after using topical warning toothpaste. -Dynamics of Microcirculation by New Blood Flow Measurement-"J. Periodontology Res.. 38・5. (2003)

    • Related Report
      2002 Annual Research Report
  • [Publications] 藤村 朗: "Analysis of the three-dimensional lymphatic architecture of the periodontal tissue using a new 3D reconstruction method"Microscopy Research and Technique. 56・1. 60-65 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] 大澤 得二: "The honeycomb structure in the lamina lucida of epidermal basement membrane during metamorphosis of Rana temporaria ornativentris"Journal of Morphology. 254・1. 92-98 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] 大澤 得二: "Real electron microscopic images of collagen fibrils in the endoneurium"Journal of Electron Microscopy. 51・5. 341-345 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] 藤村 朗 他: "Changes in the lymphatic architecture in the labial gingiva at the mandibular lncisor after carbon dioxide laser irradiation"Microcirculation annual. 17. 55-56 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] 山岸 篤, 藤村 朗, 野坂 洋一郎: "The effect of warming dentrifrice on improvement of gingivititis.-Evaluation of microcirculation by cross correlation between laser specie signal"Microcirculation annual. 17. 155-156 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] 大澤 得二, 馮 新顔, 他: "Degeneration and regeneration of the lip mucosal epithelial after cryo treatment in mice"Cells Tissues and Organes. 169. 144-151 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] 野坂洋一郎, 他: "Angiogenesis and microcirculation of a autogenous gingival garaft"International Microcirculation. 7. (2002)

    • Related Report
      2001 Annual Research Report
  • [Publications] 小野寺 政雄, 藤村 朗, 他: "Clinical evaluation og gingivitis after using topical warming toothpastes.-Dynamics of Microcirculation by new blood flow measurement-"International Microcirculation. 7. (2002)

    • Related Report
      2001 Annual Research Report
  • [Publications] 下豊 留玲, 藤村 朗, 他: "Improvement of macromolecular clearance via lymph flow in Hamster gingival by low-power carbon dioxide laser-irradiation"Lasers in Surgery and Medicine. 29. 442-447 (2001)

    • Related Report
      2001 Annual Research Report

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Published: 2002-04-01   Modified: 2016-04-21  

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