| Project/Area Number |
13672010
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Conservative dentistry
|
|---|
| Research Institution | Showa University |
|---|
Principal Investigator |
MANABE Atsufumi Showa University, School of Dentistry, Assistant, 歯学部, 講師 (40199906)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
NUMAZAWA Satoshi Showa University, School of Pharmacy, Assistant Professor, 薬学部, 助教授 (80180686)
YOSHIDA Takemi Showa University, School of Pharmacy, Professor, 薬学部, 教授 (20138415)
NAKAYAMA Sadao Showa University, Nursing and Rehabilitation Science, Professor, 保健医療学部, 教授 (00054007)
ITOH Kazuo Showa University, School of Dentistry, Assistant Professor, 薬学部, 助教授 (30129811)
|
|---|
| Project Period (FY) |
2001 – 2002
|
| Project Status |
Completed (Fiscal Year 2002)
|
| Budget Amount *help |
¥3,100,000 (Direct Cost: ¥3,100,000)
Fiscal Year 2002: ¥1,100,000 (Direct Cost: ¥1,100,000)
Fiscal Year 2001: ¥2,000,000 (Direct Cost: ¥2,000,000)
|
|---|
| Keywords | 2-HEMA / GM / allergy / delayed / 2-HEMA抗体 / 特異染色 |
|---|
| Research Abstract |
Purpose of present study was compared to the penetration 2-HEMA ana Glycerol mono methacrylate (GM) in the skin and oral mucous.
The animal used a total of 14 animals, after carrying out preliminary breeding of the SD system female rat for about one week. The strange method of Guinea pig maximization Test was tried. That is, after performing general anesthesia, 0.3ml was respectively applied to right-and-left cheek membrane, and it scraped. Then, it applied to cheek membrane again similarly as after [one week] secondary feeling the rat back after one-week breeding was shaved, and the skin reaction 24 or 48 hours after an application was observed for the monomer.
2-HEMA was penetrated the muscle layer.
|
