| Project/Area Number |
13672064
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
補綴理工系歯学
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| Research Institution | Matsumoto Dental University |
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Principal Investigator |
ITO Michio Matsumoto Dental University Professor, 歯学部, 教授 (70064681)
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| Co-Investigator(Kenkyū-buntansha) |
MIZOGUCHI Toshihide Matsumoto Dental University Assistant, 付置研究所, 助手 (90329475)
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| Project Period (FY) |
2001 – 2002
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| Project Status |
Completed (Fiscal Year 2002)
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| Budget Amount *help |
¥2,700,000 (Direct Cost: ¥2,700,000)
Fiscal Year 2002: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 2001: ¥2,200,000 (Direct Cost: ¥2,200,000)
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| Keywords | chitosan / ^<60>Coy-Ray / natural high molecule / sterilization / Irradiation / Co^<60>γ線 |
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| Research Abstract |
Due to a remarkable deterioration of material properties when chitosan film is dry-heat-sterilized, chitosan film is conventionally sterilized with the gas sterilization method
However, there is a potential risk of adverse effects of gas residue on a living body system. In this study, the film was sterilized under ^<60>Coy-ray irradiation, and changes in properties were investigated. The tensile strength of chitosan film D70 (Deacetyl 70%) with a lower level of deacetyl degree markedly decreased. On the other hand, films D85 (Deacetyl 85%), and D99 (Deacetyl 99%) did not show any reduction in tensile strenghs. The tensile elongation of all films after the ^<60>Coy-ray irradiation decreased. Among them, the film (Deacetyl 70%) showed the largest reduction in tensile elongation. It was also observed that the ^<60>Coy-ray irradiation caused film discoloration of turning yellowish. The molecules of all chitosans after the ^<60>Coy-ray irradiation decreased
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