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A prospective study of depressed outpatients who visited the internal psychosomatic medicine

Research Project

Project/Area Number 13672361
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Medical sociology
Research InstitutionKyushu University

Principal Investigator

NOZAKI Takehiro  Kyushu University Hospital, Assistant Professor, 医学部附属病院, 助手 (60301339)

Co-Investigator(Kenkyū-buntansha) KUBO Chiharu  Kyushu University, Graduate School of Medical Sciences, Professor, 大学院・医学研究院, 教授 (80117100)
Project Period (FY) 2001 – 2002
Project Status Completed (Fiscal Year 2002)
Budget Amount *help
¥2,200,000 (Direct Cost: ¥2,200,000)
Fiscal Year 2002: ¥700,000 (Direct Cost: ¥700,000)
Fiscal Year 2001: ¥1,500,000 (Direct Cost: ¥1,500,000)
Keywordsmajor depressive disorder / dysthymic disorder / adjustment disorder / minor depressive disorder / prospective study / cost-effectiveness / 医療経済 / 心療内科 / うつ病 / 費用対効果性
Research Abstract

(1) The relationship between the types of depression and the outcome
We studied prospectively the relationship between the types of depression and the outcome. Subjects were recruited from outpatients visiting for the first time the Department of Psychosomatic Medicine, Kyushu University Hospital from December 1, 1999 to May 31, 2000. One hundred and fifty-seven patients met the DSM-IV diagnosis criteria of major depressive disorder, dysthymic disorder, adjustment disorder with depressive mood and depressive disorder not otherwise specified. Of these, 65 patients adequately completing treatment during the 6 months were available. We conducted follow-up evaluations at 1, 3 and 6 months after the baseline assessment using Hamilton Depression Rating Scale (HAM-D) and Zung Self-rating Depression Scale. All types of depression showed clinically significant decreases on the HAM-D scores at 3 months after and further improvements at 6-month follow-up. We discussed the meaning of treating depressed patients at the internal psychosomatic medicine.
The cost-effectiveness in treatment of depressed patients in internal psychosomatic medicine
The costs of our treatment were higher in depressed outpatients who had never been treated than in those who had been treated. However, the outcome was better in the former than in the latter. Thus, the cost-effectiveness of psychosomatic therapy in depression was higher in untreated patients than in those who had ever been treated. We conclude that proper diagnosis and treatment in early stage of depression brought higher cost-effectiveness.

Report

(3 results)
  • 2002 Annual Research Report   Final Research Report Summary
  • 2001 Annual Research Report
  • Research Products

    (23 results)

All Other

All Publications (23 results)

  • [Publications] 野崎剛弘, 他: "心療内科を受診したうつ病患者のプロスペクティブ・スタディ(第1報)-病型と治療成績との関係-"心身医学. 42. 575-585 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Takii, M., et al.: "Classification of type 1 diabetic females with bulimia nervosa into subgroups according to purging behavior"Diabetes Care. 25. 1571-1575 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Kawai, K., et al.: "Aggressive behavior and serum testosterone concentration during the maturation process of male mice : the effects of fetal exposure to bisphenolA"Enviromental Health Perspectives. 77. 292-299 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Sudo, N., et al.: "An oral introduction of intcstinal bacteria prevents the development of a long-term Th2-skewed immunological memory induced by neonatal antibiotic treatment in mice"Clin Exp Allergy. 32. 1112-1116 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Komaki, G., et al.: "Orexin-A and leptin change inversely in fasting non-obese subjects"Eur J Endocrinol. 144. 645-651 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Ando, T., et al.: "5-HT2A promoter polymorphism is not associated with aonrexia nervosa in Japanese patients"Psychiatric Genetics. 11. 157-160 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Takehiro, N., et al.: "A prospective Study of Depressed Outpatients who visited the Department of Internal Psychosomatic Medicine"Japanese Journal of Psychosomatic Medicine. 42. 575-585 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Takii, M. et al.: "Classification of type 1 diabetic females with bulimia nervosa into subgroups according to purging behavior."Diabetes Care.. 25. 1571-1575 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Kawai, K., et al.: "Aggressive behavior and serum testosterone concentration during the maturation process of male mice: the effects of fetal exposure to bisphenolA."Environmental Health Perspectives. 77. 292-299 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Sudo, N., et al.: "An oral introduction of bacteria prevents the development of a long-term Th2-skewed immunological memory induced by neonatal antibiotic treatment in mice."Clin Exp Allergy. 32. 1112-1116 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Komaki, G., et al.: "Orexin-A and leptin change inversely in fasting non-obese subjects"Eur J Endocrinol. 144. 645-651 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Ando, T., et al.: "5-HT2A promoter polymorphism is not associated with anorexia nervosa in Japanese patients."Psychiatric Genetics. 11. 157-160 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] 野崎剛弘, 他: "心療内科を受診したうつ病患者のプロスペクテイブ・スタディ(第1報)-病型と治療成績との関係-"心身医学. 42. 575-585 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Takii, M., et al.: "Classification of type 1 diabetic females with bulimia nervosa into subgroups according to purging behavior"Diabetes Care. 25. 1571-1575 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Kawai, K., et al.: "Aggressive behavior and serum testosterone concentration dung the maturation process of male mice : the effects of fetal exposure to bisphenolA"Enviromental Health Perspectives. (in press). (2003)

    • Related Report
      2002 Annual Research Report
  • [Publications] Sudo, N., et al.: "An oral introduction of intestinal bacteria prevents the development of a long-term Th2-skewed immunological memory induced by neonatal antibiotic treatment in mice"Clin Exp Allergy. 32. 1112-1116 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Komaki, G., et al.: "Orexin-A and leptin change inversely in fasting non-obese subjects"Eur J Endocrinol. 144. 645-651 (2001)

    • Related Report
      2002 Annual Research Report
  • [Publications] Ando, T., et al.: "5-HT2A promoter polymorphism is not associated with aonrexia nervosa in Japanese patients"Psychiatric Genetics. 11. 157-160 (2001)

    • Related Report
      2002 Annual Research Report
  • [Publications] 野崎剛弘(久保木富房編): "食べられないやめられない"日本評論社. 240 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Komaki, G., at al.: "Orexin-A and leptin change inversely in fasting non-obese subjects"Eur J Endocrinol. 144. 645-651 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Oyama, N., et al.: "Antibiotic use during infancy promotes a shift in the TH1/TH2 balance toward"J. Allergy Clin Immunol. 107(1). 153-159 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Xiao-Nian Yu, et al.: "Central and peripheral catecholamines regulate the exercise-induced elevation of plasma interleukin 6 in rats"Life Science. 69. 46-52 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] 野崎剛弘(久保木富房編): "食べられないやめられない"日本評論社. 240 (2002)

    • Related Report
      2001 Annual Research Report

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Published: 2001-04-01   Modified: 2016-04-21  

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