| Project/Area Number |
13680056
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
体育学
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| Research Institution | Japan Women's College of Physical Education |
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Principal Investigator |
AKAMA Takao Japan Women's College of Physical Education, Faculty of Physical Education, Department of Sports and Health and Fitness, Assistant Professor, 体育学部, 助教授 (60212411)
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| Co-Investigator(Kenkyū-buntansha) |
KONO Ichiro University of Tsukuba, Institute of Health and Sport Sciences, Professor, 体育科学系, 教授 (00132994)
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| Project Period (FY) |
2001 – 2002
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| Project Status |
Completed (Fiscal Year 2002)
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| Budget Amount *help |
¥3,400,000 (Direct Cost: ¥3,400,000)
Fiscal Year 2002: ¥1,800,000 (Direct Cost: ¥1,800,000)
Fiscal Year 2001: ¥1,600,000 (Direct Cost: ¥1,600,000)
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| Keywords | exercise / secretory immnnoglobulin A / upper respiraton tract infection / immunity / ICAM-1 |
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| Research Abstract |
1. Alteration of secretory immunoglobulin A (slgA) in saliva and the incidence of upper respiratory tract infection (URTI).
Levels of sIgA in saliva and the incidence of URTI were investigated for four months. There were no relations in the number of affection days with URTI and the mean levels of slgA. Some subjects decreased sIgA in saliva during URTI.
2. Effects of endurance running on levels of soluble intercellular adhesion molecule 1 (sICAM-1) in saliva.
Levels of sICAM-1 in saliva were measured before and after marathon running. After running, sICAM-1 increased in the similar way as total protein. These data showed that sICAM-1 might not have relations with the post-exercise immune suppression.
3. Effects of an acute bout of exercise on levels of sIgA in saliva.
Salivary sIgA decreased after exhaustion with 80%VO2max exercise using a cycle ergometer. It was suggested that short maximum exercise caused reduction in salivary sIgA.
4. Mechanism of post-exercise reduction in salivary sIgA
We exercised rats until exhaustion. We collected saliva from rats before and after exercise. Salivary IgA levels of rats decreased after exercise. But the expression levels of polymeric immunoglobulin receptor did not alter with exercise.
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