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Development of evaluation method of mental and language disorders by spatio-temporal analysis of information on brain activities in preconscious process

Research Project

Project/Area Number 13680926
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Biomedical engineering/Biological material science
Research InstitutionThe University of Tokyo

Principal Investigator

ITOH Kenji  The University of Tokyo, Graduate School of Medicine, Research Associate (80010106)

Co-Investigator(Kenkyū-buntansha) IWANAMI Akira  The University of Tokyo, Fac of Med Hospital, Assoc Prof (80276518)
YUMOTO Masato  The University of Tokyo, Fac of Med Hospital, Research Assoc (30240170)
UNO Akira  Nat Center Neurol Psychiatr, Nat Inst MH, 精神保健研究所, Gen Manager (researcher) (10270688)
KOSHIDA Ichiro  Tokyo Univ of Technology, Fac of Eng, Prof (00192055)
Project Period (FY) 2001 – 2002
Project Status Completed (Fiscal Year 2002)
Budget Amount *help
¥3,700,000 (Direct Cost: ¥3,700,000)
Fiscal Year 2002: ¥1,300,000 (Direct Cost: ¥1,300,000)
Fiscal Year 2001: ¥2,400,000 (Direct Cost: ¥2,400,000)
Keywordscognitive disorder / language disorder / music cognition / preconscious / gamma band oscillation / coherence / EEG / MEG / brain functional mapping / MMN / ガンマ波 / 脳波 / 脳磁図 / スクランブル文
Research Abstract

We aimed to establish the objective evaluation method of human mental and language disorders in preconscious process in relation to spatial cognitive functions on the basis of neurosynaptic circuit model of bilateral auditory systems.
1. We investigated the relationships among brain evoked activities, brain functions, mental as well as language disorders, and psychotherapeutic agent based on the coordinations between neurotransmitters and modulators.
2. To establish the method of testing and quantifying on mental and kanguage disorders, we developed an online experimental system for mental and language tasks with audiovisual presentation.
3. We completed a program for mapping 3D scalp current densities of multi-channel EEG/MEG temoral data and source modeling.
4. We improved the program for dynamical presentation of 3D mapping.
5. We tried to apply the system to clinical and engineering use for evaluation of mental and language disorders.

Report

(3 results)
  • 2002 Annual Research Report   Final Research Report Summary
  • 2001 Annual Research Report
  • Research Products

    (28 results)

All 2002 Other

All Journal Article (13 results) Book (1 results) Publications (14 results)

  • [Journal Article] No effect of gender on tonal and phonetic mismatch negativity in normal adults2002

    • Author(s)
      Kasai K, ltoh K, Koshida I, Iwanami A, et al
    • Journal Title

      Cognitive Brain Research 13

      Pages: 305-312

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Journal Article] Impaired cortical network for preattentive detection of change in speech sounds2002

    • Author(s)
      Kasai K, Itoh K, Koshida I, Iwanami A, et al
    • Journal Title

      American Journal of Psychiatry 156

      Pages: 546-553

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Journal Article] 音楽課題によるγ帯域脳磁場反応2002

    • Author(s)
      湯本真人, 松田眞樹, 伊藤憲治, 他
    • Journal Title

      第32回日本臨床神経生理学会学術大会予稿集 32

      Pages: 109-109

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Journal Article] 言語理解とγ波同期発振2002

    • Author(s)
      越田一郎, 伊藤憲治, 植月美希, 他
    • Journal Title

      第32回日本臨床神経生理学会学術大会予稿集 32

      Pages: 110-110

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Journal Article] 聴覚誘発磁場成分の回復曲線による分裂病の感覚関門機能障害の評価2002

    • Author(s)
      湯本真人, 斉藤治, 伊藤憲治, 他
    • Journal Title

      電子情報通信学会技術研究報告 TL2002

      Pages: 27-30

    • NAID

      110003314160

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Journal Article] 楽譜と楽音の照合課題施行時における誘発脳磁場-音楽専門家と非専門家との比較から2002

    • Author(s)
      松田眞樹, 湯本真人, 伊藤憲治, 他
    • Journal Title

      電子情報通信学会技術研究報告 TL2002

      Pages: 31-35

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Journal Article] 「研究成果報告書概要(和文)」より2002

    • Author(s)
      宇野彰, 加我君孝, 伊藤憲治, 他
    • Journal Title

      高次神経機能障害の臨床実践入門-小児から老人,診断からリハビリテーション,福祉まで(新興医学出版社)

      Pages: 1-129

    • Related Report
      2002 Final Research Report Summary
  • [Journal Article] No effect of gender on tonal and phonetic mismatch negativity in normal adults2002

    • Author(s)
      Kasai K, Itoh K, Koshida I, et al
    • Journal Title

      Cognitive Brain Research 13

      Pages: 305-312

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Journal Article] Impaired cortical network for preattentive detection of change in speech sounds2002

    • Author(s)
      Kasai K, Itoh K, Koshida I, et al
    • Journal Title

      American Journal of Psychiatry 156

      Pages: 546-553

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Journal Article] Gamma band MEG responses in music tasks2002

    • Author(s)
      Yumoto M, Matsuda M, Itoh K, et al
    • Journal Title

      Proc 32th Conf Jpn Soc Clin Neurophysiol 32

      Pages: 109-109

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Journal Article] Language comprehension and Gamma band oscillation2002

    • Author(s)
      Koshida I, Itoh K, Uetsuki M, et al
    • Journal Title

      Proc 32th Conf Jpn Soc Clin Neurophysiol 32

      Pages: 110-110

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Journal Article] Evaluation on function disorders of sensory gating in schizophrenia by AEMF2002

    • Author(s)
      Yumoto M, Saito O, Itoh K, et al
    • Journal Title

      IEICE Tech Rep TL2002

      Pages: 27-30

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Journal Article] Evoked magnetic fields in matching task between musica notes and musical tones2002

    • Author(s)
      Matsuda M, Yumoto M, Itoh K, et al
    • Journal Title

      IEICE Tech Rep TL2002

      Pages: 31-35

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Book] Clinical Introduction of Higher nervous function disorders2002

    • Author(s)
      Uno A, Kaga K, Itoh K, et al
    • Publisher
      Shinko-Igaku Pub
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Kasai K, Itoh K, Koshida I, Iwanami A, et al.: "No effect of gender on tonal and phonetic mismatch negativity in normal adults as assessed by a high-resolution EEG recording"Cognitive Brain Research. 13・3. 305-312 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Kasai K, Itoh K, Koshida I, Iwanami A, et al.: "Impaired cortical network for preattentive detection of change in speech sounds in schizophrenia : a high-resolution event-related potential study"American Journal of Psychiatry. 156・4. 546-553 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] 湯本真人, 松田眞樹, 伊藤憲治, 宇野彰, 加我君孝, 越田一郎, 他: "音楽課題によるγ帯域脳磁場反応"第32回日本臨床神経生理学会学術大会予稿集. 32・1. 109-109 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] 越田一郎, 伊藤憲治, 植月美希, 岩波明, 福田正人, 丹羽真一, 他: "言語理解とγ波同期発振"第32回日本臨床神経生理学会学術大会予稿集. 32・1. 110-110 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] 湯本真人, 斉藤治, 伊藤憲治, 宇野彰, 金子裕, 松田眞樹, 加我君孝: "聴覚誘発磁場成分の回復曲線による分裂病の感覚関門機能障害の評価"電子情報通信学会技術研究報告. TL2002・29. 27-30 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] 松田眞樹, 湯本真人, 伊藤憲治, 宇野彰, 加我君孝: "楽譜と楽音の照合課題施行時における誘発脳磁場-音高に関する音楽専門家と非専門家との比較から-"電子情報通信学会技術研究報告. TL2002・30. 31-35 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] 宇野彰, 伊藤憲治, 他: "高次神経機能障害の臨床実践入門-小児から老人,診断からリハビリテーション,福祉まで"新興医学出版社. 129 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Kasai K, Itoh K, et al.: "Brain lateralization for mismatch response to across and within-category change of vowels"NeuroReport. 12・11. 2467-2471 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] 植月美希, 伊藤憲治, 他: "音声言語理解におけるプロソディの役割:事象関連電位による検討"電子情報通信学会技術研究報告. 101・349. 17-24 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] 越田一郎, 伊藤憲治, 他: "複数脳機能情報呈示システムによる言語認知活動の解析"臨床神経生理学. 29・2. 127-127 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Kasai K, Itoh K, et al.: "Do high or low doses of anxiolytics and hypnotics affect mismatch negativity in schizophrenic subjects? An EEG and MEG study"Clinical Neurophysiology. 113・1. 141-150 (2002)

    • Related Report
      2001 Annual Research Report
  • [Publications] Mazuka R, Itoh K, et al.: "Event-Related Potential for Scrambled Word Order in Japanese"Brain and Language. (in press). (2002)

    • Related Report
      2001 Annual Research Report
  • [Publications] 越田一郎, 伊藤憲治, 他: "動画によるRPT対話分析"2002年電子情報通信学会総合大会講演論文集. (in press). (2002)

    • Related Report
      2001 Annual Research Report
  • [Publications] Mazuka R, ltoh K, et al.: "East Asian Language Processing(Nakayama M, ed)"CSL1, Stanford University ; Stanford(in press). (2002)

    • Related Report
      2001 Annual Research Report

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Published: 2001-04-01   Modified: 2016-04-21  

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