| Project/Area Number |
14103014
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| Research Category |
Grant-in-Aid for Scientific Research (S)
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| Allocation Type | Single-year Grants |
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| Research Field |
Synthetic chemistry
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| Research Institution | The University of Tokyo |
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Principal Investigator |
FUJITA Makoto The University of Tokyo, School of Engineering, Department of Applied Chemistry, Professor, 大学院工学系研究科, 教授 (90209065)
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| Co-Investigator(Kenkyū-buntansha) |
KAWANO Masaki The University of Tokyo, School of Engineering, Department of Applied Chemistry, Associate Professor, 大学院工学系研究科, 助教授 (30247217)
YOSHIZAWA Michito The University of Tokyo, School of Engineering, Department of Applied Chemistry, Research Associate, 大学院工学系研究科, 助手 (70372399)
SATO Sota The University of Tokyo, School of Engineering, Department of Applied Chemistry, Research Associate, 大学院工学系研究科, 助手 (40401129)
富永 昌英 東京大学, 大学院・工学系研究科, 助手 (60361507)
楠川 隆博 東京大学, 大学院・工学系研究科, 助手 (70300720)
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| Project Period (FY) |
2002 – 2006
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| Project Status |
Completed (Fiscal Year 2006)
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| Budget Amount *help |
¥113,620,000 (Direct Cost: ¥87,400,000、Indirect Cost: ¥26,220,000)
Fiscal Year 2006: ¥22,880,000 (Direct Cost: ¥17,600,000、Indirect Cost: ¥5,280,000)
Fiscal Year 2005: ¥22,880,000 (Direct Cost: ¥17,600,000、Indirect Cost: ¥5,280,000)
Fiscal Year 2004: ¥27,430,000 (Direct Cost: ¥21,100,000、Indirect Cost: ¥6,330,000)
Fiscal Year 2003: ¥34,320,000 (Direct Cost: ¥26,400,000、Indirect Cost: ¥7,920,000)
Fiscal Year 2002: ¥6,110,000 (Direct Cost: ¥4,700,000、Indirect Cost: ¥1,410,000)
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| Keywords | Self-assembly / Nano-scale / Functionalization / Macrocycle / Catenane / Spherical complex / Peptide / Diels-Alder reaction / Pd(II)錯体 / プリズム状錯体 / チューブ状錯体 / トリアジン環合成 / ホスト・ゲスト / 孤立空間 / チューブ錯体 / テンプレート / 有限集積 / ナノ / 錯形成 / 遷移金属錯体 / 光反応 / パラジウム錯体 / ナノ構造 / 多面体構造 / ナノ空間 / 分子集合 / プログラム集合 |
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| Research Abstract |
In this project, we have focused on the synthesis and function of nano-scale molecular materials by programmed molecular self-assembly utilizing transition metals. Here we summarize our research results that are divided into the five topics. (1)Self-assembly of endo-functionalized molecular spheres : we succeeded in the formation of a liquid-like fluorous droplet, composed of 24 perfluoroalkyl chains confined in the interior of a 5-nanometer-sized, roughly spherical shell. The structures were spontaneously assembled in solution from 12 palladium ions and 24 bridging ligands. (2)Photo-switchable molecular catenate : We achieved a precise, clean molecular lock that operates by light. Since the inert Pt(II)-py bond is considerably labialized upon UV irradiation, we demonstrated the photo-switchable molecular lock by the one-way catenation of coordination rings. (3)Selective recognition and folding of oligopeptides by self-assembled hosts : We anticipated that the large hydrophobic cavity of self-assembled hosts could replace the protein scaffolds and stabilize the secondary structures of oligopeptides. (4)Unusual chemical reactions within self-assembled hosts : We found that an aqueous self-assembled cage induces highly unusual regioselectivity in the Diels-Alder reactions of anthracene and phthalimide molecules, promoting reaction at a terminal ring. (5)Direct crystallographic observation of unstable transition species within self-assembled hosts : We succeeded in the in situ crystallographic observation of a coordinatively unsaturated metal complex within a self-assembled coordination cage.
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