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A Cohort Study of Higher Brain Function and Motor-Kinesthetic Function in Middle and Old Age People

Research Project

Project/Area Number 14201010
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Research Field 実験系心理学
Research InstitutionNagoya University

Principal Investigator

HATTA Takeshi  Nagoya University, Graduate School of Environmental Studies, Department of Psychology, Professor, 環境学研究科, 教授 (80030469)

Co-Investigator(Kenkyū-buntansha) KAWAGUCHI Jun  Nagoya University, Graduate School of Environmental Studies, Department of Psychology, Professor, 大学院・環境学研究科, 教授 (70152931)
IIDAKA Tetsuya  Nagoya University, Graduate School of Medicine, Dept.Psychiatry, Assoc.Professor, 大学院・医学系研究科, 助教授 (70324366)
KARASAWA Kaori  Nagoya University, Graduate School of Environmental Studies, Department of Psychology, Assoc.Professor, 大学院・環境学研究科, 助教授 (50249348)
HASEGAWA Yukiharu  Nagoya University, Graduate School of Medicine, Dept.Psychiatry, Assoc.Professor, 大学院・医学系研究科, 助教授 (50208500)
YOSHIZAKI Kazuhito  Aichi-Syukutoku University, School of Communication, Professor, コミュニケーション学部, 教授 (80220614)
Project Period (FY) 2002 – 2005
Project Status Completed (Fiscal Year 2005)
Budget Amount *help
¥30,940,000 (Direct Cost: ¥23,800,000、Indirect Cost: ¥7,140,000)
Fiscal Year 2005: ¥7,410,000 (Direct Cost: ¥5,700,000、Indirect Cost: ¥1,710,000)
Fiscal Year 2004: ¥7,930,000 (Direct Cost: ¥6,100,000、Indirect Cost: ¥1,830,000)
Fiscal Year 2003: ¥7,540,000 (Direct Cost: ¥5,800,000、Indirect Cost: ¥1,740,000)
Fiscal Year 2002: ¥8,060,000 (Direct Cost: ¥6,200,000、Indirect Cost: ¥1,860,000)
KeywordsAging and congnition / Prefrontal cortex function / Cohort study / Attention / Memory / Verbal fluency / Handedness / Footedness
Research Abstract

To examine the relationship between cognitive and motor-kinesthetic function in healthy middle and old people, we participated in the cohort study, which has been conducted for 23 years by Nagoya University Medical School and Fujita Medical Welfare University. We developed the Nagoya University Cognitive Assessment Battery (NU-CAB) as a research group of cognitive psychology and assessed cognitive function (basically, memory, attention and verbal abilities) of 450 to 650 people every year for four years.
Based on the data collected for four years, the followings findings were revealed ;
1).Cognitive abilities that related to prefrontal cortex deteriorate from age around 50 years old in normal healthy people.
2).There are so-called rare-elite survivors who are above 75 years old and they are maintaining proper level of cognitive and motor-kinesthetic function.
3).There are certain relationships between cognitive function and motor-kinesthetic function that suggests strong relation between prefrontal cortex and cerebro-cerebeller connection.
4).There are certain relationships between cognitive function and socio-psychological habits such as drinking, smoking and physical exercise.
5).There are certain relationships between cognitive function and living style such as participation of leisure activities.

Report

(5 results)
  • 2005 Annual Research Report   Final Research Report Summary
  • 2004 Annual Research Report
  • 2003 Annual Research Report
  • 2002 Annual Research Report
  • Research Products

    (35 results)

All 2006 2005 2004 Other

All Journal Article (18 results) Book (3 results) Publications (14 results)

  • [Journal Article] Effects of the use of cigarettes on the function of frontal lobe in middle and upper middle-aged Japanese adults.2006

    • Author(s)
      Hatta, T., Okumura, M., Nagahara, N., Ito, E., Ito, Y., Aoki, K.
    • Journal Title

      Psychologia 49

      Pages: 1-9

    • NAID

      130001896445

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] 言語流暢性課題の信頼性と妥当性の検討2006

    • Author(s)
      伊藤恵美, 八田武志
    • Journal Title

      神経心理学 (印刷中)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Effects of the use of cigarettes on the function of frontal lobe in middle and upper middle-aged Japanese adults.2006

    • Author(s)
      Hatta, T., Okumura, M., Nagahara, N., Ito, E., Ito, Y., Aoki, K.
    • Journal Title

      Psychologia (In press)

    • NAID

      130001896445

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Lower-limb laterality in early and late middle age.2005

    • Author(s)
      Hatta, T., Ito, Y., Matsuyama, Y., Hasegawa, Y.
    • Journal Title

      Laterality 10

      Pages: 267-277

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Annual Research Report 2005 Final Research Report Summary
  • [Journal Article] 中高年者を対象とする単語記憶と散文記憶の基準値について2005

    • Author(s)
      八田武志, 永原直子, 岩原昭彦, 伊藤恵美
    • Journal Title

      人間環境学研究 3

      Pages: 7-12

    • NAID

      130004953245

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Annual Research Report 2005 Final Research Report Summary
  • [Journal Article] Effects of learning experience on bihemispheric processing.2005

    • Author(s)
      Yoshizaki, K., Hatta, T.
    • Journal Title

      International Journal of Neurosicence 115

      Pages: 923-934

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Annual Research Report 2005 Final Research Report Summary
  • [Journal Article] 前頭葉認知機能と前庭・視床・小脳平衡機能との関連について・行動指標による検討2005

    • Author(s)
      八田武志, 伊藤恵美, 増井徹男, 松山幸弘, 長谷川幸治
    • Journal Title

      人間環境学研究 3

      Pages: 7-15

    • NAID

      40007103670

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Annual Research Report 2005 Final Research Report Summary
  • [Journal Article] Three word recall and logical memory recall in normal aging2005

    • Author(s)
      Hatta, T., Nagahara, N., Iwagara, A., Ito, E.
    • Journal Title

      Journal of Human Environmental Studies 3

      Pages: 7-12

    • NAID

      130004953245

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Effects of learning experience on bihemispheric processing.2005

    • Author(s)
      Yoshizaki, K., Hatta, T.
    • Journal Title

      International Journal of Neuroscience 115

      Pages: 923-934

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Behavioral evidence on the relationship between prefrontal cortex and cerebro-cerebeller functions.2005

    • Author(s)
      Hatta, T., Ito, Y., Masui, T., Matsuyama, Y., Hasegawa, Y.
    • Journal Title

      Journal of Human Environmental Studies 3

      Pages: 7-15

    • NAID

      130004545627

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Lower-limb asymmetries in early and late middle age.2005

    • Author(s)
      Hatta, T., et al.
    • Journal Title

      Laterality 10(In press)

    • Related Report
      2004 Annual Research Report
  • [Journal Article] The effects of learning experience on bihemispheric processing.2005

    • Author(s)
      Yoshizaki, K., Hatta, T.
    • Journal Title

      International Journal of Neuroscience 115(7)(in press)

    • Related Report
      2004 Annual Research Report
  • [Journal Article] 健常成人の言語流暢性検査の結果について2004

    • Author(s)
      伊藤恵美, 八田武志他
    • Journal Title

      神経心理学 20

      Pages: 1-8

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Handedness and footedness in members of general Japanese population2004

    • Author(s)
      Kawakami, A., Hatta, T., Ito, Y.
    • Journal Title

      Journal of Human Environmental Studies 2

      Pages: 51-55

    • NAID

      130004545623

    • Related Report
      2004 Annual Research Report
  • [Journal Article] 住民検診を対象とした認知機能検査バッテリ(NU-CAB)作成の試み2004

    • Author(s)
      八田武志
    • Journal Title

      人間環境学研究 2

      Pages: 15-20

    • NAID

      130004545620

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Spatial frequency of visual image modulates neural responses in the temporo-occipital lobe. An investigation with event-related fMRI.2004

    • Author(s)
      Iidaka T, et al.
    • Journal Title

      Cognitive Brain Research 18(2)

      Pages: 196-204

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Verbal fluency tasks in Japanese healthy subjects.

    • Author(s)
      Ito, E., Hatta, T.
    • Journal Title

      Japanese Journal of Neuropsychology (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] 言語流暢性課題の信頼性と妥当性の検討

    • Author(s)
      伊藤恵美, 八田武志
    • Journal Title

      神経心理学 (印刷中)

    • Related Report
      2005 Annual Research Report
  • [Book] D-CAT(注意機能スクリーニング検査)使用手引き 改訂版2006

    • Author(s)
      八田武志, 伊藤保弘, 吉崎一人
    • Total Pages
      44
    • Publisher
      ファブリック出版
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Book] D-CAT (Revised version) Manual2006

    • Author(s)
      Hatta, T., Ito, Y., Yoshizaki, K.
    • Publisher
      Osaka : Fabric Press
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Book] D-CAT(注意機能スクリーニング検査)使用手引き改訂版2006

    • Author(s)
      八田武志, 伊藤保弘, 吉崎一人
    • Total Pages
      44
    • Publisher
      ファブリック出版
    • Related Report
      2005 Annual Research Report
  • [Publications] Hatta, T., et al.: "Relations between the prefrontal cortex and cerebro-cerebeller functions"Applied Neuropsychology. 11(In press). (2004)

    • Related Report
      2003 Annual Research Report
  • [Publications] Yoshizaki, Hatta: "Hemisphere metacontrol of a mental addition task in right and left handers"Journal of Human Environmental Studies. 1. 1-8 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] Hatta, T., et al.: "Differential processing of implicature in individuals with left and right brain damage"Journal of Clinical and Experimental Neuropsychology. 67(In press). (2004)

    • Related Report
      2003 Annual Research Report
  • [Publications] Karasawa, et al.: "Depression among Japanese informal caregivers for elderly people"Psychology, Health and Medicine. 8. 371-376 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] Iidaka T, et al.: "Spatial frequency of visual image modulates neural responses in the temporo-occipital lobe"Cognitive Brain Research. 18. 196-204 (2004)

    • Related Report
      2003 Annual Research Report
  • [Publications] Iidaka T, et al.: "Dissociable neural responses in the hippocampus to the retrieval of facial identity and emotion : An event-related fMRI study"Hippocampus. 13. 429-436 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 八田武志: "脳のはたらきと行動のしくみ"医歯薬出版. 187 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 八田武志: "住民検診データから見た加齢と認知機能について"老年期痴呆研究会誌. 13(印刷中). (2003)

    • Related Report
      2002 Annual Research Report
  • [Publications] Hatta, T., et al.: "Effects of type of cognitive demands on bilateral advantage in interhemispheric processing"Psychological Research. 66. 133-142 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Karasawa, K: "Responsibility attribution and support provision in an intergroup context : An examination in a simulated society game"Japanese Psychological Research. 44. 196-208 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] lmazai, K., Ohbuchi, K.: "Conflict resolution and procedural fairness in Japanese work organizations"Japanese Psychological Research. 44. 107-112 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] lidaka T., et al.: "Age-related differences in the medial temporal lobe responses to emotionalfaces as revealed by fMRl"Hippocampus. 12. 352-362 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Nakamura, H., et al.: "Two cases of functional focal retrograde amnesia with impairment of objects use"Cortex. 38. 613-622 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] 八田武志: "D-CAT(注意機能素クリーニング検査)"ユニオンプレス. 109 (2002)

    • Related Report
      2002 Annual Research Report

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Published: 2002-04-01   Modified: 2016-04-21  

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