| Project/Area Number |
14350465
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
有機工業化学
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| Research Institution | Tokyo Institute of Technology |
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Principal Investigator |
KITAZUME Tomoya Tokyo Institute of Technology, Graduate School of Bioscience and Biotechnology, Professor, 大学院・生命理工学研究科, 教授 (30092547)
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| Project Period (FY) |
2002 – 2005
|
| Project Status |
Completed (Fiscal Year 2005)
|
| Budget Amount *help |
¥14,600,000 (Direct Cost: ¥14,600,000)
Fiscal Year 2005: ¥2,200,000 (Direct Cost: ¥2,200,000)
Fiscal Year 2004: ¥2,500,000 (Direct Cost: ¥2,500,000)
Fiscal Year 2003: ¥2,500,000 (Direct Cost: ¥2,500,000)
Fiscal Year 2002: ¥7,400,000 (Direct Cost: ¥7,400,000)
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| Keywords | ionic liquid / aldolase antibody / fluorinated material / Michael addition / Bayllis-Hillman type reaction / gelation / reaction system / aldol reaction / グリーンケミストリー / マイクロファクトリー / 再使用可能 / フッ素化合物 / 進化型反応場 / マイクロリアクター / 機能性 / 担持 / 酸化反応 / 環化反応 / 持続可能 / 繰り返し / 環境 / アルドール反応 / 選択性 / 抗体酵素 / 有機不斉触媒 |
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| Research Abstract |
The aim of this research area was to develop a few reaction fields by using ionic liquids as media, and to create many functional liquids by designing the composite ions. In this research, I have found that the synthetic utilities of ionic liquids for the synthesis of fluorinated materials via Michael addition with the Bayllis-Hillman type reaction, and for the synthesis of 2-substituted 3-tri-(or di-)fluoromethyl-2-propenals with the high level selectivity of geometric isomers. Further, I have reported the utility of reusable ionic liquid-proline (or aldolase antibody 38C2) reaction system, proceeding the aldol reactions.
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