| Project/Area Number |
14370590
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Functional basic dentistry
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| Research Institution | Tokyo Institute of Technology |
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Principal Investigator |
KUDO Akira Tokyo Institute of Technology, Guraduate School of Bioscience and Biotechnology, Professor, 大学院・生命理工学研究科, 教授 (70178002)
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| Co-Investigator(Kenkyū-buntansha) |
MORIYAMA Keiji The University of Tokushima, School of Dentistry, Professor, 歯学部, 教授 (20262206)
竹下 淳 東京工業大学, 大学院・生命理工学研究科, 助手 (50263009)
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| Project Period (FY) |
2002 – 2003
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| Project Status |
Completed (Fiscal Year 2003)
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| Budget Amount *help |
¥14,000,000 (Direct Cost: ¥14,000,000)
Fiscal Year 2003: ¥5,000,000 (Direct Cost: ¥5,000,000)
Fiscal Year 2002: ¥9,000,000 (Direct Cost: ¥9,000,000)
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| Keywords | Cadherin-11 / Osteo-linegae / Teratoma / mesenchymal cells / 骨芽細胞 / ペリオスチン / メカニカルストレス |
|---|
| Research Abstract |
We studied Cadherin-11 function in the differentiation of osteoblasts.
Teratomas harbouring the Cadherin-11 gene generated bone and cartilage preferentially. Cadherin-11 transfectants of C2C12 cells and Cadherin-11 and/or N-cadherin transfectants of L cells demonstrated that Cadherin-11.
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