| Project/Area Number |
14380395
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
SAITO Hirokazu Institute of Biomaterials and Bioengineering, Division of Biosystems, Technical Official, 生体材料工学研究所, 教務職員 (00205668)
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| Co-Investigator(Kenkyū-buntansha) |
MITSUBAYASHI Kohji Institute of Biomaterials and Bioengineering, Division of Biosystems, Professor, 生体材料工学研究所, 教授 (40307236)
OTUSKA Kimio Institute of Biomaterials and Bioengineering, Division of Biosystems, Associate Professor, 生体材料工学研究所, 助教授 (00211798)
OGAWA Mitsuhiro Institute of Biomaterials and Bioengineering, Division of Biosystems, Research Associate, 生体材料工学研究所, 助手 (30322085)
NAKAMURA Masato Institute of Biomaterials and Bioengineering, Division of Biosystems, Associate Professor, 生体材料工学研究所, 助教授 (90301803)
TOGAWA Tatsuo Waseda University, Graduate School of Human Sciences, Professor, 大学院・人間科学研究科, 特任教授 (40013859)
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| Project Period (FY) |
2002 – 2004
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| Project Status |
Completed (Fiscal Year 2004)
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| Budget Amount *help |
¥10,200,000 (Direct Cost: ¥10,200,000)
Fiscal Year 2004: ¥1,500,000 (Direct Cost: ¥1,500,000)
Fiscal Year 2003: ¥3,500,000 (Direct Cost: ¥3,500,000)
Fiscal Year 2002: ¥5,200,000 (Direct Cost: ¥5,200,000)
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| Keywords | Needle / Puncture / Vibration / PZT / Tension |
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| Research Abstract |
In blood sampling and drug injection, the needle should quickly puncture to the blood vessel for decreasing the pain. It is thought that high-speed needle penetration would restrain the tissue deformation that was depending on the viscoelasticity of the tissue, and then stimulation and damage in the free end nervous system would be decreased. In this study, we discussed the effectiveness of needle puncturing with impulse vibration for restraining the tissue deformation and nervous system damage. Elastic rubbers that were like human skin of the viscoelasticity were punctured by blood sampling needles with 2.5 mm/s of the speed, with micro vibration of sine, rectangular and saw-tooth waveform, and 0, 10, 100, 1k, 10k and 100k Hz of the frequency. The puncture forces were monitored and the waveforms were evaluated. It was confirmed that micro vibration mainly decreased frictional force between the needle wall and the elastic rubber. However, decrease of puncture force did not depend on the frequency of the vibration. In addition, application of 10 % expansion to elastic rubber decreased of 40% in puncture force and reduced puncture time to half. The reduction of puncture time means decrease of movement of the target point of needle puncture, and was seemed effective to prevent medical mishaps of needle puncture to blood vessel such as internal haemorrhage.
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