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SYNTHESIS OF FERRIMAGNETIC CERAMIC MICROSPHERES FOR LOCAL HYPERTHERMIA OF DEEP-SEATED CANCER

Research Project

Project/Area Number 14550800
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field 無機工業化学
Research InstitutionKyoto University

Principal Investigator

KAWASHITA Masakazu  KYOTO UNIVERSITY, GRADUATE SCHOOL OF ENGINEERING, ASOCIATE RESEARCHER, 工学研究科, 助手 (70314234)

Project Period (FY) 2002 – 2003
Project Status Completed (Fiscal Year 2003)
Budget Amount *help
¥3,200,000 (Direct Cost: ¥3,200,000)
Fiscal Year 2003: ¥800,000 (Direct Cost: ¥800,000)
Fiscal Year 2002: ¥2,400,000 (Direct Cost: ¥2,400,000)
KeywordsMICROSPHERE / FERRIMAGNETISM / MAGNETITE / DEEP-SEATED CANCER / HYPERTHERMIA / HYSTERESIS LOSS / PRECIPITATION / HIGH-FREQUENCY INDUCTION THERMAL PLASMA / 温熱治療 / 磁気ヒステリシス損 / 高周波誘導熱プラズマ溶融法 / β-FeOOH / 水溶液折出法
Research Abstract

Pure Fe_3O_4 microspheres 20-30 μm in diameter can be prepared by melting powders in high-frequency induction thermal plasma and subsequent heat treatment. The heat-treated microspheres show the heat generation, 10 W・g^<-1>, under 300 0e and 100 kHz. The microspheres 20-30 μm in diameter containing small crystals of Fe_3O_4 50 nm in size can be prepared by a precipitation from solution and subsequent heat treatment. The heat-treated microspheres show the heat generation, 41 W・g^<-1>, under 300 0e and 100 kHz. The microspheres prepared by a precipitation from solution and subsequently subjected to heat treatment can be a promising candidate of thermoseeds for hyperthermia of cancer, since they can show a n excellent heat generating ability.

Report

(3 results)
  • 2003 Annual Research Report   Final Research Report Summary
  • 2002 Annual Research Report
  • Research Products

    (20 results)

All Other

All Publications (20 results)

  • [Publications] M.Kawashita: "Preparation of magnetite microspheres for hypertermia of cancer"KEY ENGINEERING MATERIALS. 218-220. 645-658 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] M.Kawashita: "Ceramic microspheres for in situ radiotherapy of cancer"Mater.Sci.and Engin.C. C22. 3-8 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] M.Kawashita: "Preparation of ceramic microspheres for in situ radiotherapy of deep-seated cancer"Biomaterials. 24. 2955-2963 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] M.Kawashita: "Ceramic microspheres for in situ treatment of cancer"Proc.CIMTEC2002. 6. 111-122 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] 川下将一: "放射性ベクトルセラミックス-がんを治療する放射性あるいは強磁性セラミック微小球"バイオマテリアル-生体材料. 21. 368-376 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] 川下将一: "深部がん温熱治療のための強磁性微小球"New Glass. 18. 27-31 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] M.KAWASHITA: "PREPARATION OF MAGNETITE MICROSPHERES FOR HYPERTERMIA OF CANCER"KEY ENGINEERING MATERIALS. 218. 645-658 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] M.KAWASHITA: "CERAMIC MICROSPHERES FOR IN SITU RADIOTHERAPY OF CANCER"MATER.SCI. AND ENGIN.C. C22. 3-8 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] M.KAWASHITA: "PREPARATION OF CERAMIC MICROSPHERES FOR IN SITU RADIOTHERAPY OF DEEP-SEATED CANCER"BIOMATERIALS. 24. 2955-2963 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] M.KAWASHITA: "CERAMIC MICROSPHERES FOR IN SITU TREATMENT OF CANCER"PROC.CIMTEC2002. 6. 111-122 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] M.KAWASHITA: "RADIOACTIVE VECTOR CERAMICS -RADIOACTIVE OR FERRIMAGNETIC CERAMIC MICROSPHERES FOR CANCER TREATMENT"BIOMATERIAL-SEITAIZAIRYO. 2. 368-376 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] M.KAWASHITA: "FERRIMAGNETIC MICROSPHERES FOR LOCAL HYPERTHERMIA OF DEEP-SEATED CANCER"NEW GLASS. 18. 27-31 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] M.KAWASHITA: "RESEARCH ON CERAMIC MICROSPHERES FOR MINIMALLY INVASIVE AND LOCAL TREATMENT OF CANCER"BIOMATERIAL-SEITAIZAIRYO. 22. 36-42 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] M.KAWASHITA: "PREPARATION OF GLASS-CERAMICS CONTAINING FERRIMAGNETIC ZINC-IRON FERRITE FOR THE HYPERTHERMAL TREATMENT OF CANCER"J.CERAM.SOC.JAPAN. (IN PRESS).

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] 川下 将一: "放射性ベクトルセラミックス-がんを治療する放射性あるいは強磁性セラミック微小球"バイオマテリアル-生体材料. 21. 368-376 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 川下 将一: "深部がん局所温熱治療のための強磁性微小球"NEW GLASS. 18. 27-31 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 川下 将一: "低侵襲局所がん治療用セラミック微小球"バイオマテリアル-生体材料. 22. 36-42 (2004)

    • Related Report
      2003 Annual Research Report
  • [Publications] M.Kawashita: "Ceramic microspheres for in situ radiotherapy of cancer"Mater. Sci. and Engin. C. C22. 3-8 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] M.Kawashita: "Preparation of ceramic microspheres for in situ radiotherapy of deep-seated cancer"Biomaterials. (印刷中).

    • Related Report
      2002 Annual Research Report
  • [Publications] M.Kawashita: "Ceramic microspheres for in situ treatment of cancer"Proc. CIMTEC2002. (印刷中).

    • Related Report
      2002 Annual Research Report

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Published: 2002-04-01   Modified: 2016-04-21  

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