| Budget Amount *help |
¥3,400,000 (Direct Cost: ¥3,400,000)
Fiscal Year 2004: ¥1,100,000 (Direct Cost: ¥1,100,000)
Fiscal Year 2003: ¥1,100,000 (Direct Cost: ¥1,100,000)
Fiscal Year 2002: ¥1,200,000 (Direct Cost: ¥1,200,000)
|
|---|
| Research Abstract |
When a certain amount of methionine and lysine were administered into the abomasums of calves via the reticular groove, an increase in intakes of CP or TDN or both from basal diets increased N retention, but decreased plasma concentrations of free methionine, branched-chain amino acids(BCAA) and phenylalanine. The decrease of these amino acids in the plasma could result from increased N retention, but increased intakes of CP or TDN or both from basal diets did not affect plasma concentrations of free lysine despite the increased N retention. Thus, it could not be denied that some factors other than increased N retention might also stimulate the methionine metabolism. However, methionine imbalance was not compensated by the abomasal administration of BCAA and phenylalanine. In addition, when D- or L-methionine was administered into the abomasums, plasma concentrations of BCAA and phenylalanine did not differ between the two isomers of methionine, although plasmas methionine concentration was lower when L-methionine that is more rapidly metabolized was administered. These results would not sustain the possibility that the metabolism of BCAA and phenylalanine relates to the methionine metabolism. Next, we examined if excess arginine could cause argine-lysine antagonism in calves, because abomasal administration of higher amounts of L-lysineHCl resulted in an occurrence of diarrhea, which disturbed confirming the occurrence of lysine-arginine antagonism in calves. As a result, excess lysine did not cause the arginine-lysine antagonism in calves even when as much as 120 g/d of L-arginineHCl was administered, although imbalance and toxicity could occur, suggesting that lysine-arginine antagonism would not occur in calves.
|
