| Project/Area Number |
14570322
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Public health/Health science
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| Research Institution | University of Tsukuba |
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Principal Investigator |
YANAGI Hisako University of Tsukuba, Graduate School of Comprehensive Human Science, Assistant Professor, 大学院・人間総合科学研究科, 助教授 (10241811)
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| Co-Investigator(Kenkyū-buntansha) |
TOMURA Shigeo University of Tsukuba, Graduate School of Comprehensive Human Science, Professor, 大学院・人間総合科学研究科, 教授 (60100955)
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| Project Period (FY) |
2002 – 2004
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| Project Status |
Completed (Fiscal Year 2004)
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| Budget Amount *help |
¥3,400,000 (Direct Cost: ¥3,400,000)
Fiscal Year 2004: ¥1,000,000 (Direct Cost: ¥1,000,000)
Fiscal Year 2003: ¥1,000,000 (Direct Cost: ¥1,000,000)
Fiscal Year 2002: ¥1,400,000 (Direct Cost: ¥1,400,000)
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| Keywords | osteoporosis / premonopausal / body mass index / menstrual dysfunction / cessation of exercise / bone mineral density / follow-up study / 遺伝素因 / 環境要因 / 体重変化 / 運動継続 |
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| Research Abstract |
We conducted a follow-up study to investigate the relationships between bone mineral density(BMD) loss and body composition, menstrual status, and environmental and nutritional factors in healthy, premenopausal Japanese women.
One hundred thirty-eight subjects aged 20-48years participated in this study. BMD was measured for the L2-L4 lumbar spine (LBMI) by dual energy X-ray absorptiometry (DXA). Mean follow-up time was 405±82 days. In multiple linear regression analysis, the annual change rate of BMI, menstrual dysfunction, and the cessation of exercise during the follow-up period was independent determinant for annual change rate of LBMI, respectively.
BMI change, menstrual dysfunction, and cessation of exercise may be associated with annual BMI change in apparently healthy premenopausal Japanese women.
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