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Study on risk assessment of subclinical neurobehavioral effects of environmental factors

Research Project

Project/Area Number 14570325
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Public health/Health science
Research InstitutionMie University (2003)
The University of Tokyo (2002)

Principal Investigator

YOKOYAMA Kazuhito  Mie University, Faculty of Medicine, Professor, 医学部, 教授 (00158370)

Project Period (FY) 2002 – 2003
Project Status Completed (Fiscal Year 2003)
Budget Amount *help
¥3,400,000 (Direct Cost: ¥3,400,000)
Fiscal Year 2003: ¥2,000,000 (Direct Cost: ¥2,000,000)
Fiscal Year 2002: ¥1,400,000 (Direct Cost: ¥1,400,000)
KeywordsChemical substances / Subclinical effects / Neurobebavioral effects / Risk assessment / Risk management / Epidemiology / 神経行動障害 / 非顕性影響 / リスクマネージメント
Research Abstract

Risk assessment is a process to avoid, reduce or manage the risk. In environmental health, risk assessment is conducted as quantification of incidence of the events which are harmful to health of target populations. Indices used for risk assessment include mortality or mortality rate, loss of life expectancy etc, which are called end-point. The present study was aimed at establishing a method for the risk assessment of subclinical neurobehavioral effects of environmental factors. For this purpose, literatures on the effects of chemicals such as lead, solvents, etc were collected and carefully reviewed. Also, dose-effect (response) relationships of various chemicals were examined through field studies among human populations. The results have been presented at scientific meetings as well as international scientific journals. By this effort, exposure limit of occupational exposure to acrylamide by Japan Society of Industrial Health has been amended.

Report

(3 results)
  • 2003 Annual Research Report   Final Research Report Summary
  • 2002 Annual Research Report
  • Research Products

    (19 results)

All Other

All Publications (19 results)

  • [Publications] Yokoyama, K.: "Computerized posturography with sway frequency analysis : application in occupational and environmental health."Industrial Health. 40. 14-22 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Yokoyama, K.: "Subclinical cerebellar anterior lobe, vestibule-cerebellar and spinocerebellar afferente effects in young female lead workers in China : computerized posturography with sway frequency analysis and brainstem auditory evoked potentials."Industrial Health. 40. 245-253 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Ueno, S.: "Effects of pH and temperature on force and stiffness of skeletal muscle fibers during contraction and relaxation in relation to musculoskeletal disorders."Industrial Health. 40. 362-369 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Rusli, B.N.: "Effects of safety behaviours with pesticide use on occurrence of acute symptoms in male and female tobacco-growing Malaysian farmers."Industrial Health. 40. 182-190 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Onuki, M.: "Assessment of urinary cotinine as a marker of nicotine absorption from tobacco leaves : a study on tobacco farmers in Malaysia."Journal of Occupational Health. 45. 140-145 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Piao, F.: "Subacute toxic effects of zinc on various tissues and organs of rats."Toxicology Letters. 145. 28-35 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Vigeh, M.: "Increased blood lead in pregnancy hypertension in women without occupational lead exposure, Tehran, Iran."Archives of Environmental Health. (inpress).

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Yokoyama, K: "Computerized posturography with sway frequency analysis: application in occupational and environmental health"Industrial Health. 40. 14-22 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Yokoyama, K: "Subclinical cerebellar anterior lobe, vestibule-cerebellar and spinocerebellar afferent effects in young female lead workers in China: computerized posturography with sway frequency analysis and brainstem auditory evoked potentials."Industrial Health. 40. 245-253 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Ueno, S: "Effects of pH and temperature on force and stiffness of skeletal muscle fibers during contraction and relaxation in relation to musculoskeletal disorders."Industrial Health. 40. 362-369 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Rusli, B.N: "Effects of safety behaviours with pesticide use on occurrence of acute symptoms in male and female tobacco-growing Malaysian farmers."Industrial Health. 40. 182-190 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Onuki, M: "Assessment of urinary cotinine as a marker of nicotine absorption from tobacco leaves: a study on tobacco farmers in Malaysia."Journal of Occupational Health. 45. 140-145 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Piao, F: "Subacute toxic effects of zinc on various tissues and organs of rats."Toxicology Letters 145. 28-35 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Vigeh, M: "Increased blood lead in pregnancy hypertension in women without occupational lead exposure, Tehran, Iran."Archives of Environmental Health. (in press).

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Ueno, S.: "Effects of pH and tempera- ture on force and stiffness of skeletal muscle fibers during contraction and relaxation in relation to musculoskeletal disorders"Industrial Health. 40. 362-369 (2002)

    • Related Report
      2003 Annual Research Report
  • [Publications] 横山和仁: "鉛中毒-最近のレビューより"産業医学ジャーナル. 25. 86-90 (2002)

    • Related Report
      2003 Annual Research Report
  • [Publications] Vigeh, M.: "Increased blood lead in gestational hypertension : A study on women without occupational lead exposure in Teheran Iran"The 17th Asian Conference on Occupational Health, Taipei, Taiwan. (2002)

    • Related Report
      2003 Annual Research Report
  • [Publications] Onuki, M.: "Assessment of urinaly cotinine as a marker of nicotine exposure from tabacco leaves : A study on tabacco-growing farmers in Malaysia"The 17th Asian Conference on Occupational Health, Taipei, Taiwan. (2002)

    • Related Report
      2003 Annual Research Report
  • [Publications] Onuki, M.: "Assessment of urinary cotinine as a marker of nicotine absorption from tobacco leaves"Journal of Occupational Health. 45(印刷中). (2003)

    • Related Report
      2002 Annual Research Report

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Published: 2002-04-01   Modified: 2016-04-21  

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