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Prevention and treatment of osteoporosis related fractures

Research Project

Project/Area Number 14571378
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Orthopaedic surgery
Research InstitutionTottori University

Principal Investigator

HAGINO Hiroshi  Tottori University, University Hospital, Associate Professor, 医学部附属病院, 助教授 (80208412)

Co-Investigator(Kenkyū-buntansha) OKANO Toru  Tottori University, Faculty of Medicine, Assistant Professor, 医学部, 講師 (60252871)
KATAGIRI Hiroshi  Tottori University, Faculty of Medicine, Research Associate, 医学部, 助手 (60304226)
Project Period (FY) 2002 – 2004
Project Status Completed (Fiscal Year 2004)
Budget Amount *help
¥3,100,000 (Direct Cost: ¥3,100,000)
Fiscal Year 2004: ¥700,000 (Direct Cost: ¥700,000)
Fiscal Year 2003: ¥1,000,000 (Direct Cost: ¥1,000,000)
Fiscal Year 2002: ¥1,400,000 (Direct Cost: ¥1,400,000)
KeywordsOsteoporosis / Insufficiency Fractures / Risk Factors for Fractures / Quality of Life(QOL) / Hip Fractures / Distal Radius Fractures / Proximal Humeral Fractures / QOL
Research Abstract

1.Risk factors for osteoporosis related fractures
We conducted a case-control study to elucidate risk factors for fractures of distal radius and proximal humerus. We found greater frequency of going outside and better ability of long gait were significant risk factors, and futon use (instead of bed use) was a protective factor for distal radius fractures. On the other hand, greater frequency of going outside significantly decreased the risk of proximal humerus fractures. Falling tendency was a significant risk factor for both fractures.
2.Sequential QOL changes in patients with osteoporosis related fractures
We evaluated quality of life (QOL) in 115 patients 45 year-old and over (mean:73.5 year-old) with osteoporosis related fractures. Out of the 115 patients, 35 were vertebral fractures (VF) (all treated conservatively), 35 were hip fractures(HF)(all treated surgically), and 45 were distal radius fractures (RF) (20 treated conservatively, 25 treated surgically). QOL was evaluated using EuroQol (EQ-5D). Mean health related QOL scores in VF were 0.89,0.50,0.75, and 0.74, before, just after, 3 months after, and 6 months after the fracture, respectively, and did not recover until 12 months after the fracture. In HF, they were 0.74,0.39,0.60, and 0.60, respectively, and did not recover until 12 months after the fracture. In RF, they were 0.91,0.70,0.83, and 0.80, respectively, and recovered 12 months after the fracture.
3.Treatment cost of osteoporosis related fractures
Among the subjects we evaluated QOL, we investigated the treatment cost of the fractures in hospitals which allowed this survey. As a result, the costs in hospital were 480 thousand yen in VF, 1,736 thousand yen in HF, and 98 thousand yen in RF.

Report

(4 results)
  • 2004 Annual Research Report   Final Research Report Summary
  • 2003 Annual Research Report
  • 2002 Annual Research Report
  • Research Products

    (33 results)

All 2005 2004 2003 2002 Other

All Journal Article (23 results) Book (2 results) Publications (8 results)

  • [Journal Article] 高齢者の骨折2005

    • Author(s)
      萩野 浩
    • Journal Title

      理学療法ジャーナル 39

      Pages: 5-11

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Annual Research Report 2004 Final Research Report Summary
  • [Journal Article] Fractures in the elderly (in Japanese)2005

    • Author(s)
      Hagino H
    • Journal Title

      Physiotherapy Journal 39

      Pages: 5-11

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] 高齢者の転倒・骨折の実態とその予防のための生活設計2004

    • Author(s)
      萩野 浩
    • Journal Title

      CLINICAL CALCIUM 14・3

      Pages: 357-363

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Annual Research Report 2004 Final Research Report Summary
  • [Journal Article] Case-control Study of Risk Factors for Fractures of the Distal Radius and Proximal Humerus among the Japanese Population2004

    • Author(s)
      Hagino H, 他
    • Journal Title

      Osteoporos Int 15・3

      Pages: 226-230

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Annual Research Report 2004 Final Research Report Summary
  • [Journal Article] 大腿骨頚部骨折とQOL2004

    • Author(s)
      萩野 浩
    • Journal Title

      骨粗鬆症治療 3・2

      Pages: 134-139

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Annual Research Report 2004 Final Research Report Summary
  • [Journal Article] 骨粗鬆症と骨折予防2004

    • Author(s)
      萩野 浩
    • Journal Title

      総合リハ 32・10

      Pages: 917-922

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Annual Research Report 2004 Final Research Report Summary
  • [Journal Article] 高齢者大腿骨近位部骨折の疫学2004

    • Author(s)
      萩野 浩
    • Journal Title

      関節外科 23

      Pages: 1529-1533

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Annual Research Report 2004 Final Research Report Summary
  • [Journal Article] Case-control Study of Risk Factors for Fractures of the Distal Radius and Proximal Humerus among the Japanese Population2004

    • Author(s)
      Hagino H, et al.
    • Journal Title

      Osteoporos Int 15(3)

      Pages: 226-230

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Falls and fractures in elderly people, and life style for their prevention (in Japanese)2004

    • Author(s)
      Hagino H
    • Journal Title

      Clin Calcium 14(3)

      Pages: 357-363

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Hip fracture and quality of life (in Japanese)2004

    • Author(s)
      Hagino H
    • Journal Title

      Osteoporosis Treatment 3(2)

      Pages: 134-139

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Osteoporosis and fracture prevention (in Japanese)2004

    • Author(s)
      Hagino H
    • Journal Title

      Sogo Rehabilitation 32(10)

      Pages: 917-922

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Epidemiology of the hip fracture in the elderly (in Japanese)2004

    • Author(s)
      Hagino H
    • Journal Title

      Joint Surgery 23

      Pages: 1529-1533

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] 大腿骨頚部骨折の疫学2003

    • Author(s)
      萩野 浩
    • Journal Title

      MB Ortho 16・12

      Pages: 1-7

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Epidemiology of the hip fracture (in Japanese)2003

    • Author(s)
      Hagino H
    • Journal Title

      MB Orthop 16(2)

      Pages: 1-7

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Osteoporosis (in Japanese)2003

    • Author(s)
      Hagino H
    • Journal Title

      Medicine and Molecular Biology

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] 高齢者の四肢骨折と生活運動機能障害2002

    • Author(s)
      萩野 浩
    • Journal Title

      整形・災害外科 45

      Pages: 745-752

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] 骨粗鬆症関連骨折の疫学と対策2002

    • Author(s)
      萩野 浩
    • Journal Title

      Medical Practice 19

      Pages: 1699-1702

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] オステオポローシスと骨折,QOL2002

    • Author(s)
      片桐浩史, 萩野 浩, 豊島良太
    • Journal Title

      関節外科 21

      Pages: 1254-1259

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] 骨粗鬆症.骨粗鬆症治療の費用対効果分析2002

    • Author(s)
      萩野 浩
    • Journal Title

      日本臨牀 60

      Pages: 645-654

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Disability of musculoskeletal function in daily living due to limb fractures in the elderly (in Japanese)2002

    • Author(s)
      Hagino H
    • Journal Title

      Seisaigeka 45

      Pages: 745-752

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Epidemiology and strategies for osteoporosis related fractures (in Japanese)2002

    • Author(s)
      Hagino H
    • Journal Title

      Medical Practice 19

      Pages: 1699-1702

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Osteoporosis fractures and QOL (in Japanese)2002

    • Author(s)
      Katagiri H, Hagino H, et al.
    • Journal Title

      Joint Surgery 21

      Pages: 1254-1259

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Cost-effectiveness of the treatment for osteoporosis (in Japanese)2002

    • Author(s)
      Hagino H
    • Journal Title

      Nippon Rinsho 60

      Pages: 645-654

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Book] 看護のための最新医学講座 医学と分子生物学(分担執筆)2003

    • Author(s)
      萩野 浩
    • Total Pages
      5
    • Publisher
      骨粗鬆症
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Book] 今日の治療指針(分担執筆)2003

    • Author(s)
      萩野 浩
    • Total Pages
      3
    • Publisher
      骨粗鬆症
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Publications] 萩野 浩: "大腿骨頚部骨折の疫学"MB Ortho. 16・12. 1-7 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] Hagino H, Fujiwara S, Nakashima E, Nanjo Y, Teshima R: "Case-control Study of Risk Factors for Fractures of the Distal Radius and Proximal Humerus among the Japanese Population"Osteoporos Int. 15. 226-230 (2004)

    • Related Report
      2003 Annual Research Report
  • [Publications] 萩野 浩: "大腿骨頚部骨折とQOL"骨粗鬆症治療. 3・2. 134-139 (2004)

    • Related Report
      2003 Annual Research Report
  • [Publications] 萩野 浩: "高齢者の転倒・骨折の実態とその予防のための生活設計"CLINICAL CALCIUM. 14・3. 357-363 (2004)

    • Related Report
      2003 Annual Research Report
  • [Publications] 萩野 浩: "高齢者の四肢骨折と生活運動機能障害"整形・災害外科. 45. 745-752 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] 萩野 浩: "骨粗懸症関連骨折の疫学と対策"Medical Practice. 19. 1699-1702 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] 片桐浩史, 萩野 浩, 豊島良太: "オステオポローシスと骨折,QOL"関節外科. 21. 1254-1259 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] 萩野 浩: "骨粗鬆症.骨粗鬆症治療の費用対効果分析"日本臨床. 60. 645-654 (2002)

    • Related Report
      2002 Annual Research Report

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Published: 2002-04-01   Modified: 2016-04-21  

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