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Study of pathophysiology and treatment of superior oblique palsy.

Research Project

Project/Area Number 14571665
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Ophthalmology
Research InstitutionHAMAMATSU UNIVERSITY SCHOOL OF MEDICINE

Principal Investigator

SATO Miho  Hamamatsu University, School of Medicine, Associate professor, 医学部, 助教授 (50252242)

Co-Investigator(Kenkyū-buntansha) HOTTA Yoshihiro  Hamamatsu University, School of Medicine, Professor, 医学部, 教授 (90173608)
Project Period (FY) 2002 – 2003
Project Status Completed (Fiscal Year 2003)
Budget Amount *help
¥3,400,000 (Direct Cost: ¥3,400,000)
Fiscal Year 2003: ¥700,000 (Direct Cost: ¥700,000)
Fiscal Year 2002: ¥2,700,000 (Direct Cost: ¥2,700,000)
Keywordsstrabismus / binocularity / torsional diplopia / superior oblique muscle / macular translocation surgery / 画像診断 / 斜視手術 / 両眼視機能
Research Abstract

A superior oblique muscle has actions of infraduction, abduction and incyclotorsion. Other extra ocular muscles can compensate dysfunction of superior oblique muscle. Compare to infraduction and abduction, incyclotorsion is rarely compensated by other muscles and most patients with acquired Superior oblique palsy complain torsional diplopia. Fusional amplitude of cyclotorsion is large in normal subjects, but it is very narrow in the patients with central nervous system problems. We therefore performed the following studies on superior oblique muscles. 1) The relationship between ocular torsional movement and structure of extraocular muscles. 2) the relationship between ocular torsional movement and binocular vision.
1)In the patients with superior oblique palsy, if the superior oblique muscle is hypoplastic, patients have vertical deviation, exotropia and they often require larger number of muscles to be operated to achieve satisfactory result. We reported the effectiveness of the surgery to correct the relative position between the eyeball and extraocular muscles. We confirmed that imaging studies are important to evaluate muscle functions. We reported the position of extraocular muscles after strabismus surgery. The positions of extraocular muscles did not alter in the deep orbit. The alteration occurred only anterior to the equator.
We studied the amount of retinal rotation and subjective cyclotorsion alter macular translocation surgery. We found that the patients who underwent macular translocation surgery exceeded 1 5 degrees often complain diplopia. Normal subjects adapt cyclotorsion up to 15 degrees, and the patients who underwent macular translocation surgety also adapted up to 15 degrees of cyclotorsion. We reported that the patients whose superior oblique tendon migrating into the Tenon's capsule showed poor stereopsis and recovering binocularity after strabismus surgery was difficult.

Report

(3 results)
  • 2003 Annual Research Report   Final Research Report Summary
  • 2002 Annual Research Report
  • Research Products

    (32 results)

All Other

All Publications (32 results)

  • [Publications] M Sato他6名: "Strabological findings following macular translocation surgery with 360-degree retinotomy."Inv Ophthalmol Vis Sci. 44. 1939-1944 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] M Sato他1名: "Clinical findings and surgical results of true and masquerading congenital superior oblique palsy."Progress in strabismology. 211-214 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] M Sato他2名: "Primary monofixation syndrome in discordant monozygotic twins with strabismus."Progress in strabismology. 109-112 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] M Sato他5名: "Aniseikonia measured by hess chart and new aniseikonia tests"Progress in strabismology. 197-200 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] M Sato et al.: "Strabological findings following macular translocation surgery with 360-degree retinotomy."Inv Ophthalmol Vis Sci. 44. 1939-1944 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] M Sato et al.: "Clinical findings and surgical results of true and masquerading congenital superior oblique palsy."Progress in strabismology. 211-214 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] M Sato: "Primary monofixation syndrome in discordant monozygotic twins with strabismus."Progress in strabismology. 109-113 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] M Sato: "Aniseikonia measured by hess chart and new aniseikonia tests."Progress in strabismology. 197-200 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] 佐藤美保: "上斜節麻痺に対する手術治療"日本の眼科. 74. 457-460 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 佐藤美保: "斜視のプリズム処方について教えてください"あたらしい眼科. 臨時増刊号. 213-215 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 天野恵美: "眼鏡のトラブル「スポーツに対応できない」"眼科診療プラクテイス. 82. 30-31 (2002)

    • Related Report
      2003 Annual Research Report
  • [Publications] 佐藤美保: "眼鏡のトラブル「度数が変わりやすい」"眼科診療プラクテイス. 82. 27-29 (2002)

    • Related Report
      2003 Annual Research Report
  • [Publications] 佐藤美保: "眼科医と視能訓練士"眼科診療プラクテイス. 86. 46-57 (2002)

    • Related Report
      2003 Annual Research Report
  • [Publications] 佐藤美保: "調節を配慮した眼鏡処方-斜視の眼鏡処方-"視覚の科学. 23. 2-6 (2002)

    • Related Report
      2003 Annual Research Report
  • [Publications] M Sato: "Strabological findings following macular translocation surgery with 360-degree retinotomy"Inv Ophthalmol Vis Sci. 44. 1939-1944 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] M Sato: "Clinical findings and surgical results of true and masquerading congenital superior oblique palsy"Progress in strabismology. 211-214 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] T Yagasaki: "Primary monofixation syndrome in discordant monozygotic twins with strabismus"Progress in strabismology. 109-112 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] T Hirai: "Aniseikonia measured by hess chart and new aniseikonia tests"Progress in strabismology. 197-200 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] T Hirai: "Stereopsis of idiopathic macular hole in special reference to the size of hole and its effect on stereo acuity"Binocular Vision & Strabismus. 18. 242-248 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] T Hirai: "Loss of stereopsis with optic chiasm lesions and stereoscopic tests as a differential test"Ophthalmology. 109. 1692-1702 (2002)

    • Related Report
      2003 Annual Research Report
  • [Publications] 佐藤美保: "斜視の原因と遺伝"あたらしい眼科. 19. 1535-1542 (2002)

    • Related Report
      2003 Annual Research Report
  • [Publications] Ikeda M: "Differential development of cation-chloride cotransporters and Cl- homeostasis contributes to differential GABAergic actions between developing rat visual cortex and dorsal lateral geniculate nucleus"Brain Res. 984. 149-159 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] Miho Sato, Hiroko Terasaki, Nobuchika Ogino, et al.: "Strabismological findings following macular translocation surgery with 360-degree retinotomy"Inv Ophthalmol Vis Sci. (In press).

    • Related Report
      2002 Annual Research Report
  • [Publications] 天野恵美, 佐藤美保, 岡本洋子, 寺崎浩子, 三宅養三: "広画角デジタル眼底カメラRet Cam 120による蛍光眼底造影"臨床眼科. 57・4. (2003)

    • Related Report
      2002 Annual Research Report
  • [Publications] 古川晴子, 岡本洋子, 天野恵美, 佐藤美保: "先天小瞳孔に対する瞳孔形成術"眼科手術. (印刷中).

    • Related Report
      2002 Annual Research Report
  • [Publications] 佐藤美保: "斜視の原因と遺伝"あたらしい眼科. 19. 1535-1542 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Toshie Hirai, Miho Sato, Yozo Miyake et al.: "Loss of stereopsis with optic chiasm lesions and stereoscopic tests as a differential test"Ophthalmology. 109. 1692-1702 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Pediatric eye disease investigator group (M.Sato, et al.): "Spontaneous Resolution of Early-onset Esotropia : Experience of the Congenital Esotropia Observational Study"Am J Ophthalmol. 133. 109-118 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Pediatric eye desease investigator group (M.Sato, et al.): "The clinical spectrum of Early-onset Esotropia : Experience of the Congenital Esotropia Observational Study"Am J Ophthalmol. 102-108 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] M.Sato, H.Terasaki, E.Amano, Y.Okamoto, Y.Miyake: "Ultrasound biomicroscopic findings in Hallermann-Streiff Syndrome"Jpn J Ophthalmol. 46. 451-454 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] 野寄清美, 町田拓幸, 丸山友香, 西村香澄, 佐藤美保: "副鼻腔手術後の内直筋断裂にHummelsheim法を行った2例"眼科臨床医報. 96. 449-451 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] 浅野俊樹, 天野恵美, 岡本洋子, 佐藤美保: "若年性黄色肉芽腫の1例"眼科臨床医報. (印刷中).

    • Related Report
      2002 Annual Research Report

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Published: 2002-04-01   Modified: 2016-04-21  

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