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Electrophysiologic and Histologic Study of Blue Cone in Rabbit Retina

Research Project

Project/Area Number 14571689
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Ophthalmology
Research InstitutionChiba University (2003)
Toho University (2002)

Principal Investigator

YAMAMOTO Shuichi  Chiba University, Graduate School of Medicine, Professor, 大学院・医学研究院, 教授 (20230550)

Co-Investigator(Kenkyū-buntansha) 鶴岡 三恵子  東邦大学, 医学部, 助手 (00307737)
山本 禎子  東邦大学, 医学部, 講師 (00297706)
Project Period (FY) 2002 – 2003
Project Status Completed (Fiscal Year 2003)
Budget Amount *help
¥3,200,000 (Direct Cost: ¥3,200,000)
Fiscal Year 2003: ¥1,500,000 (Direct Cost: ¥1,500,000)
Fiscal Year 2002: ¥1,700,000 (Direct Cost: ¥1,700,000)
KeywordsBlue cone electroretinogram / LED built-in contact lens electrode / X-linked retinoschisis / Multiple evanescent white dot syndrome / Rabbit eye / 網膜電図 / 青錐体 / LED電極
Research Abstract

1)To examine the blue cone electroretinogram, we developed the blue LED built-in contact lens electrode.
2)Responses from the blue cone were clearly and repeatedly recorded from normal human eyes using this new electrode.
3)Temporal frequency characteristics obtained from the electroretinogram was quite similar those reported in previous psychophysical studies.
4)Smaller contact lenses were developed for rabbit eyes, and the blue cone electroretinograms were successfully recorded.
5)Electroretinograms were examined in patients with various retinal diseases, such as X-linked retinoschisis and multiple evanescent white dot syndrome, to study retinal function, in order to compare with those m experimental animals.

Report

(3 results)
  • 2003 Annual Research Report   Final Research Report Summary
  • 2002 Annual Research Report
  • Research Products

    (14 results)

All Other

All Publications (14 results)

  • [Publications] Yamamoto S, et al.: "Selective reduction of S-cone response and on-response in the cone electroretinograms of patients with X-linked retinoschisis"Graefe Arch Gun Exp Ophthalmol. 240. 457-460 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Yamamoto S, et al.: "S-cone electroretinograms in multiple evanescent white dot syndrome"Doc Ophthalmol. 106. 117-120 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Mitamura Y, Yamamoto S, et al.: "Monocyte chemotactic protein-1 level in the vitreous of patients with proliferative vitreoretinopathy"Jpn J Ophthalmol. 46. 218-221 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Uemoto R, Yamamoto S, et al.: "Macular configuration determined by optical coherence tomography after idiopathic macular hole surgery with or without internal limiting membrane peeling"Br J Ophthalmol. 86. 1240-1242 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Yamamoto T, Yamamoto S, et al.: "Early postoperative retinal thickness changes and complications after vitrectomy for diabetic macular edema"J Ophthalmol. 135. 14-19 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Uemoto R, Yamamoto S, Takeuchi S: "Epimacular proliferative response following internal limiting membrane peeling for idiopathic macular holes"Graefe.Arch.Clin.Exp.Ophthalmol.. 242. 177-180 (2004)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Yamamoto S, Hayashi M, Tsuruoka M, Ogata K, Tsukahara I, Yamamoto T, Takeuchi S.: "Selective reduction of Scone response and on-response in the cone electroretinograms of patients with X-linked retinoschisis."Graefe Arch Clin Exp Ophthalmol. 240. 457-460 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Yamamoto S, Hayashi M, Tsuruoka M, Yamamoto T, Tsukahara I, Takeuchi S.: "S-cone electroretinograms in multiple evanescent white dot syndrome."Doc Ophthalmol. 106. 117-120 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Mitamura Y, Takeuchi S, Yamamoto S, Yamamoto T, Tsukahara I, Matsuda A, Tagawa Y, Mizue Y, Nishihara J.: "Monocyte chemotactic protein-1 level in the vitreous of patients with proliferative vitreoretinopathy."Jpn J Ophthalmol. 46. 218-221 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Uemoto R, Yamamoto S, Aoki T, Tsukahara I, Yamamoto T, Takeuchi S.: "Macular configuration determined by optical coherence tomography after idiopathic macular hole surgery with or without internal limiting membrane peeling."Br J Ophthalmol. 86. 1240-1242 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Yamamoto T, Hitani K, Tsukahara I, Yamamoto S, Kawasaki R, Yamashita H, Takeuchi S.: "Early postoperative retinal thickness changes and complications after vitrectomy for diabetic macular edema."Am J Ophthalmol. 135. 14-19 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Uemoto R, Yamamoto S, Takeuchi S.: "Epimacular proliferative response following internal limiting membrane peeling for idiopathic macular holes."Graefe.Arch.Clin.Exp.Ophthalmol.. 242. 177-180 (2004)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Yamamoto T, Yamamoto S, et al.: "Early postoperative retinal thickness changes and complications after vitrectomy for diabetic macular edema"Am J Ophthalmol. 135. 14-19 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] Uemoto R, Yamamoto S, Takeuchi S: "Epimacular proliferative response following internal limiting membrane peeling for idiopathic macular holes"Graefe.Arch.Clin.Exp.Ophthalmol.. 242. 177-180 (2004)

    • Related Report
      2003 Annual Research Report

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Published: 2002-04-01   Modified: 2016-04-21  

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