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Contamination survey of mercury in whale products and its safety

Research Project

Project/Area Number 14572112
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Environmental pharmacy
Research InstitutionHealth Sciences University of Hokkaido

Principal Investigator

ENDO Tetsuya  Health Silences University of Hokkaido, Faculty of Pharmaceutical Silences, Assistant professor, 薬学部, 講師 (10133216)

Project Period (FY) 2002 – 2004
Project Status Completed (Fiscal Year 2004)
Budget Amount *help
¥2,900,000 (Direct Cost: ¥2,900,000)
Fiscal Year 2004: ¥300,000 (Direct Cost: ¥300,000)
Fiscal Year 2003: ¥600,000 (Direct Cost: ¥600,000)
Fiscal Year 2002: ¥2,000,000 (Direct Cost: ¥2,000,000)
KeywordsWhale / Dolphin / Methyl mercury / Tuna / Food contamination / Fetus / 養殖 / PTWI / 水銀 / クジラ(鯨) / 中毒 / 表示
Research Abstract

Contamination levels of mercury in internal organs of toothed whales sold in Wakayama Prefecture were extremely high, enough to cause the acute intoxication. The highest concentration of total mercury found in liver was about 2000 ppm (Sci. Total Environ., 300, 15-22, 2002).
Oral administration of boiled liver of toothed whale containing about 2000 ppm to rats caused the acute renal intoxication (Arch. Environ. Contain Toxicol., 44,412-416, 2003).
Marked differences in contamination levels of mercury were found among odontocete species and caught off areas (Environ. Sci. Technol., 37, 2681-2685, 2003).
The highest concentrations of total methyl mercury of methyl mercury found in red meat originating from a false killer whale were 81 and 26.2 ppm, respectively (Cehmosphere, 54, 1653-1662, 2004).
The occasional consumption of red meat from small cetaceans could pose a health problem for not only pregnant women but also for general population (Chmosphese, in press).
The organochlorine contaminants extracted from whale products was readily transferred to rat embryos in the whale embryo cultured system and caused the teratogenic effect (Organohalogen Compounds, 55, 421-423, 2003).
Marked difference in contamination levels of total mercury was found among tuna species.

Report

(4 results)
  • 2004 Annual Research Report   Final Research Report Summary
  • 2003 Annual Research Report
  • 2002 Annual Research Report
  • Research Products

    (23 results)

All 2004 2003 2002 Other

All Journal Article (15 results) Publications (8 results)

  • [Journal Article] Contamination by mercury and cadmium in the cetacean products2004

    • Author(s)
      Endo, et al.
    • Journal Title

      Chemosphere 54

      Pages: 1653-1662

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Contamination by mercury and selenium in the cetacean products from Japanses market.2004

    • Author(s)
      T.Endo, Haraguchi, K., Cipriano, F., Simmonds, M.P., Hotta, Y., Sakata, H.
    • Journal Title

      Chemosphere 54

      Pages: 1653-1662

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Identification of novel dimethoxylated polybrominated biphenyl aaacumulation in marine mammals2004

    • Author(s)
      March et al.
    • Journal Title

      Organohalogen Compounds 66

      Pages: 3823-3829

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Hemolytic crisis with fulminant hepatic failure in Wilson disease without consanguinity2004

    • Author(s)
      Kitazawa at al.
    • Journal Title

      Pediat.Int. 46

      Pages: 726-729

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Effects of P-glycoprotein inhibitors on transepithelial transport of cadmium in cultured renal epithelial cells. LLC-PK1 and LLC-GA5-COL1502004

    • Author(s)
      Endo et al.
    • Journal Title

      Toxicology 208

      Pages: 123-132

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Renal toxicity in rats after oral administration of mercury2003

    • Author(s)
      Endo, et al.
    • Journal Title

      Arch.Environ.Comtam.Toxicol. 44

      Pages: 412-416

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Mercury contamination in the red meat of whales and dolphins2003

    • Author(s)
      Endo, et al.
    • Journal Title

      Environ.Sci.Technoi. 37

      Pages: 2681-2685

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Renal toxicity in rats after oral administration of mercury-contaminated boiled whale livers marketed for human consumption.2003

    • Author(s)
      Endo, T., Haraguchi, K., Sakata, M.
    • Journal Title

      Arch.Environ.Contam.Toxicol. 44

      Pages: 412-416

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Mercury and selenium concentrations in the internal organs of2002

    • Author(s)
      Endo, et al.
    • Journal Title

      Sci.Total Environ. 3000

      Pages: 15-22

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Human health significance of organochlorine and mercury2002

    • Author(s)
      Simmonds, M.P., Haraguchi, K., Endo, T., Cipriano, F., Palumbi, S.R., Troisi, G.M.
    • Journal Title

      J.Toxicol.Environ.Health A 65

      Pages: 1211-1235

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Mercury and selenium contamination in then internal organs of toothed whales and dolphins marketed for human consumption in Japan.2002

    • Author(s)
      Endo, T., Haraguchi, K., Sakata, M.
    • Journal Title

      Sci.Total Environ. 300

      Pages: 15-22

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Human health significance of organochiorine and mercury contaminations in Japanses whale meat2002

    • Author(s)
      Simmonds, M.P., Haraguchi, K., Endo, T., Cipriano, F., Palumbi, S.R., Troise, G.M.
    • Journal Title

      J.Toxicol.Environ.Health A 65

      Pages: 1211-1235

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Distribution and toxicity of mercury in rats after oral

    • Author(s)
      Endo, et al.
    • Journal Title

      Chemosphere (In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Distribution and toxicity of mercury in rats after oral administration of mercury-contaminated whale red meat marketed for human consumption.

    • Author(s)
      T.Endo, Hotta, Y., Haraguchi, K., Sakata, H.
    • Journal Title

      Chemosphere (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Distribution and toxicity of mercury in rats after oral administration of mercury-contaminated whale red meat marketed for human consumption.

    • Author(s)
      Endo et al.
    • Journal Title

      Chemosphere (in press)

    • Related Report
      2004 Annual Research Report
  • [Publications] Endo T.: "Mercury contamination in the red meat of whales and dolphins marketed for human consumption in Japan"Environ.Sci.Technol.. 37. 2681-2685 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] Endo T.: "Contamination by mercury and cadmium in the cetacean products from Japanese market"Chemosphere. 54. 1653-1662 (2004)

    • Related Report
      2003 Annual Research Report
  • [Publications] Ohya, K.: "Presymptomatic diagnosis of Wilson disease associated with a novel"Eur. J. Pediatrics. 161. 124-126 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Simmonds, M.P.: "Human health significance of organochlorine and mercury contamination in"J. Toxicol. Environ. Health A. 65. 1211-1235 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Sasaki, K.: "Effects of extract of Ginkgo biloha leaves and its constituents on"Life Sci.. 70. 1657-1667 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Endo, T.: "Mercury and selenium concentrations in the internal organs of"Sci. Total Environ.. 300. 15-22 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Endo, T.: "Effects of P-glycoprotein inhibitors on cadmium accumulation in cultured"Toxicol. Appl. Pharmacol.. 185. 166-171 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Endo, T.: "Renal Toxicity in rats after oral administration of mercury-contaminated"Arch. Environ. Contam. Toxicol.. (In press). (2003)

    • Related Report
      2002 Annual Research Report

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Published: 2002-04-01   Modified: 2016-04-21  

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