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Lypophilic Signal Molecules on Brain Function

Research Project

Project/Area Number 14608026
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section企画調査
Research Field Neuroscience in general
Research InstitutionYOKOHAMA CITY UNIVERSITY

Principal Investigator

HAYASHI Shinji  Yokohama City University, Graduate School of Integrated Science, Professor, 大学院・総合理学研究科, 教授 (20076996)

Co-Investigator(Kenkyū-buntansha) 川戸 佳  東京大学, 大学院・総合文化研究科, 教授 (50169736)
佐久間 康夫  日本医科大学, 医学部, 教授 (70094307)
KAWATA Misuhiro  Kyoto prefecture Medical School, Professor Yasuo Sakuma, Nippon Medical School, Professor, et al., 医学部, 教授 (60112512)
加藤 茂明  東京大学, 分子細胞生物学研究所, 教授 (60204468)
筒井 和義  広島大学, 総合科学部, 教授 (20163842)
Project Period (FY) 2002
Project Status Completed (Fiscal Year 2002)
Budget Amount *help
¥3,300,000 (Direct Cost: ¥3,300,000)
Fiscal Year 2002: ¥3,300,000 (Direct Cost: ¥3,300,000)
KeywordsSteroid hormones / Thyroid hormone / Brain / Symposium / New research field / Receptor protein / Extranuclear action
Research Abstract

This research project is to propose new research field to be urgently established. To emphasize the importance of "the lypophilic signal molecules on brain function", we organized two symposia and supported three others listed below that are related to this particular research field.
1. International Symposium "Present Status of Steroid Receptors in the Brain" held as as satellite symposium of the 25th Japan Neuroscience Meeting. July 10, 2003, Yokohama. Number of speakers: 8(Organized by this Project)
2. "Lypophilic mediators and Receptor Studies", one of the Symposia in the 75th Japan Society of Biochemistry. October 15, 2002, Kyoto, Speakers: 15. (Organized by Kato, S and Shimizu T)
3. "Neurosteroids Regulate while Endocrine Disruptors Modify the Memory and Learning" Symposium in the 75th Japan Society of Biochemistry, October 15, 2002, Kyoto. Speakers: 7. (Organized by Kawato, S. and Tsutsui, K)
4. "Expression of Sex Difference, views from Brain and Behavior, Environment, Human Society and Culture" March 8, 2003, Kyoto, Speakers: 9 (Organized by this Project)
5. "Symposium on Environment and Physiology" a satellite symposium of the 80th Japan Physiology Society, March 23, 2003, Fukuoka. Speakers: 12.(Organized by Sakuma Y)

Report

(2 results)
  • 2002 Annual Research Report   Final Research Report Summary
  • Research Products

    (21 results)

All Other

All Publications (21 results)

  • [Publications] Mitra SW, Hoskin E, Hayashi S, Pfaff DW, Ogawa S, Rohrer SP, Schaeffer JM, McFwen RS, Alves SE: "Immunolocalization of estrogen receptor beta in the mouse brain : comparison with estrogen receptor alpha"Endocrinology. 144. 2055-2067 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Towart LA, Alves SE, Znamensky V, Hayashi S, McEwen BS, Milner TA: "Subcellualr relationships between cholinergic terminals and estrogen receptor alpha in the dorsal hippocampus"J. Comp. Neurol.. (in press). (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Tanaka T, Shiina T, Hayashi S, Okamura H, Kamomae H, Kaneda Y: "Estrogen receptor alpha expression in the medial preoptic area and the medial basal hypothalamus under different physiological conditions in cattle"J. Reprod. Dev.. 49.1. 55-60 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Kawano H, Honma S, Honma A, Hayashi S, Kawano Y: "Melanin-concentrating hormone : the wide web that controls feeding"Anat. Sci. Int.. 77. 149-160 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Orikasa C, Kondo Y, Hayashi S, McEwen BS, Sakuma Y: "Sexually dimorphic expression of estrogen receptor beta in the anteroventral periventricular nucleus of the rat preoptic area : Implication in luteinizing hormone surge"Proc Soc Nat Acad Sci, USA. 99.5. 3306-3311 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Adams MM, Fink SE, Shah RA, Janasen WGM, Hayashi S, Milner TA, McEwen BS, Morrison JH: "Estrogen and aging impact the subcellular distribution of estrogen receptor-alpha in the hippocampus of female rats"J Neurosci.. 22.9. 3608-3614 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Ikeda Y, Nagai A, Ikeda M, Hayashi S: "Increased expression of Mullerian-inhibiting substance correlates with inhibition of follicle growth in the developing ovary of rats treated with E2 benzoate"Endocrinology, 143:304-312 (2002). 143. 304-312 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] 林しん治: "性のホルモン科学 その5 脳内エストロゲン受容体"日本比較内分泌学会 ニュース. 109. 4-11 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Mitra SW, Hoskin E, Yudkovitz j, Pear L, Wilkinson HA, Hayashi S, Pfaff DW, Ogawa S, Rohrer SP, Schaeffer JM, McEwen BS, Alves SE: "Immunolocalization of estrogen receptor beta in the mouse brain: comparison with estrogen receptor alpha"Endocrinology. 144. 2055-2067 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Towart LA, Alves Sem Znamensky V, Hayashi S, McEwen BS, Milner TA: "Subcellualr relationships between cholinergic terminals and estrogen receptor alpha in the dorsal hippocampus"J. Comp. Neurol. in press. (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Tanaka T, Shiina T, Hayashi S, Okamura H, Kamomae H, Kaneda Y: "Estrogen receptor alpha expression in the medial preoptic area and the medial basal hypothalamus under different physiological conditions in cattle"J. Reprod. Dev. 49(1). 55-60 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Kawano H, Honma S, Honma A, Hayashi S, Kawano Y: "Melanin-concentrating hormone: the wide web that controls feeding."Anat. Sci. Int.. 77. 149-160 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Orikasa C, Kondo Y, Hayashi S, McEwen BS, Sakuma Y: "Sexually dimorphic expression of estrogen receptor beta in the anteroventral per ventricular nucleus of the rat preoptic area"Implication in luteinizing hormone surge, Proc Soc Nat Acad Sci, USA. 99(5). 3306-3311 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Adams MM, Fink SE, Shah RA, Janssen WGM, Hayashi S, Milner TA, McEwen BS, Morrison JH: "Estrogen and aging impact the subcellular distribution of estrogen receptor-alpha in the hippocampus of female rats"J Neurosci. 22(9). 3608-3614 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Ikeda Y, Nagai A, Ikeda M, Hayashi S: "Increased expression of Mullerian-inhibiting substance correlates with inhibition of follicle growth in the developing ovary of rats treated with E2 benzoate"Endocrinology. 143. 304-312 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Towart LA, Alves SE, Znamensky V, Hayashi S, McEwen BS, Milner TA: "Subcellualr relationships between cholinergic terminals and estrogen receptor alpha in the dorsal hippocampus"J. Comp. Neurol.. (2003,in press). (2003)

    • Related Report
      2002 Annual Research Report
  • [Publications] Tanaka T, Shiina T, Hayashi S, Okamura H, Kamomae H, Kaneda Y: "Estrogen receptor alpha expression in the medial preoptic area and the medial basal hypothalamus under different physiological cnditions in cattle"J. Reprod. Dev.. 49.1. 55-60 (2003)

    • Related Report
      2002 Annual Research Report
  • [Publications] Kawano H, Honma S, Honma A, Hayashi S, Kawano Y: "Melanin-concentrating hormone : the wide web that controls feeding"Anat. Sci. Int.. 77. 149-160 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Orikasa C, Kondo Y, Hayashi S, McEwen BS, Sakuma Y: "Sexually dimorphic expression of estrogen receptor beta in the anteroventral periventricular nucleus of the rat preoptic area : Implication in luteinizing hormone surge"Proc Soc Nat Acad Sci, USA. 99.5. 3306-3311 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Adams MM, Fink SE, Shah RA, Janssen WGM, Hayashi S, Milner TA, McEwen BS, Morrison JH.: "Estrogen and aging impact the subcellular distribution of estrogen receptor-alpha in the hippocampus of female rats"J Neurosci.. 22.9. 3608-3614 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Ikeda Y, Nagai A, Ikeda M, Hayashi S: "Increased expression of Mullerian-inhibiting substance correlates with inhibition of follicle growth in the developing ovary of rats treated with E2 benzoate"Endocrinology, 143:304-312(2002). 143. 304-312 (2002)

    • Related Report
      2002 Annual Research Report

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Published: 2002-04-01   Modified: 2016-04-21  

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