• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

ケニア辺境2地域における寄生虫感染のリスク要因と慢性栄養失調の原因解明

Research Project

Project/Area Number 14J10486
Research Category

Grant-in-Aid for JSPS Fellows

Allocation TypeSingle-year Grants
Section国内
Research Field Eating habits
Research InstitutionNagasaki University

Principal Investigator

凪 幸世  長崎大学, 医歯薬学総合研究科(医学系), 特別研究員(PD) (90772971)

Project Period (FY) 2014-04-25 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥2,000,000 (Direct Cost: ¥2,000,000)
Fiscal Year 2015: ¥900,000 (Direct Cost: ¥900,000)
Fiscal Year 2014: ¥1,100,000 (Direct Cost: ¥1,100,000)
Keywords住血吸虫症 / 慢性栄養失調 / NTD / マラリア / ケニア
Outline of Annual Research Achievements

ケニア国西部ビクトリア湖畔のビタ県において、学童のマンソン住血吸虫症の感染リスクが居住地に依存し、その感染強度は人口密度と関連することを明らかにした。また空間疫学手法を用いて、同県における疾病集積地域を見出した (PLoS NTD, 2014)。さらに、同症を疫学的に捕捉することを目的とした診断用抗原を検索し、種特異的な調査を可能とする抗原 (SERPIN) と種に依存しない抗原(RP26)を共同研究により明らかにした (PLoS NTD, 2015)。マンソン住血吸虫症は慢性栄養失調(低身長)と関連しており、本研究から血中アルブミン値と善玉コレステロール(high density lipoprotein: HDL)値の低下との関連が示されたため、これらの知見に関して現在原著論文として執筆中である。

Research Progress Status

27年度が最終年度であるため、記入しない。

Strategy for Future Research Activity

27年度が最終年度であるため、記入しない。

Report

(2 results)
  • 2015 Annual Research Report
  • 2014 Annual Research Report
  • Research Products

    (13 results)

All 2015 2014 Other

All Journal Article (3 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 3 results,  Open Access: 3 results,  Acknowledgement Compliant: 2 results) Presentation (9 results) (of which Int'l Joint Research: 2 results,  Invited: 1 results) Remarks (1 results)

  • [Journal Article] Species-Specific Serological Detection for Schistosomiasis by Serine Protease Inhibitor (SERPIN) in Multiplex Assay.2015

    • Author(s)
      Tanigawa C, Fujii Y, Miura M, Nzou SM, Mwangi AW, Nagi S, Hamano S, Njenga SM, Mbanefo EC, Hirayama K, Mwau M, Kaneko S
    • Journal Title

      PLoS Negl Trop Dis.

      Volume: 9巻8号 Issue: 8 Pages: 1-17

    • DOI

      10.1371/journal.pntd.0004021

    • NAID

      120006986925

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Introduction of a community water supply in rural Western Kenya: impacts on community wellbeing and child health2015

    • Author(s)
      Kayako Sakisaka, Evans Chadeka, Sachiyo Nagi, Dorcas Shambi Mwandembo, Masamine Jimba
    • Journal Title

      Journal of International Health

      Volume: 7 Issue: 3 Pages: 204-211

    • DOI

      10.1093/inthealth/ihv015

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Risk Factors and Spatial Distributions of Schistosoma mansoni infection among Primary School Children in Mbita, western Kenya2014

    • Author(s)
      Sachiyo Nagi, Evans Chadeka, Toshihiko Sunahara, Faith Mutungi, Yombo K. Dan Justin, Satoshi Kaneko, Yoshio Ichinose, Sohkichi Mastumoto, Sammy M. Njenga, Masahiro Hashizume, Masaaki Shimada and Shinjiro Hamano
    • Journal Title

      PLoS Neglected Tropical Disease

      Volume: 8 Issue: 7 Pages: 1-10

    • DOI

      10.1371/journal.pntd.0002991

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Presentation] Risk Factors and Spatial Distribution of Schistosoma mansoni Infection among Primary School Children in Mbita District, Western Kenya2015

    • Author(s)
      凪幸世, Evans Chadeka, 砂原俊彦, Faith Mutungi, Yombo K. Dan Justin, 金子聡, 一瀬休生, 松本壮吉, 橋爪真弘, 嶋田雅暁, 濱野真二郎
    • Organizer
      第56回日本熱帯医学会
    • Place of Presentation
      大阪大学(大阪府)
    • Year and Date
      2015-12-04
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] Spatial distribution of Schistosoma mansoni and Plasmodium falciparum infections among young children residing around Lake Victoria in Mbita, western Kenya2015

    • Author(s)
      Nagi Sachiyo, Evans Chadeka, Benard C Ngetich, Toshihiko Sunahara and Shinjiro Hamano
    • Organizer
      American Society of Tropical Medicine and Hygiene (ASTMH)
    • Place of Presentation
      フィラデルフィア(アメリカ)
    • Year and Date
      2015-10-26
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 西ケニアビタ地域における住血吸虫症とマラリアの空間分布とリスク要因の解明2015

    • Author(s)
      凪幸世, Evans Chadeka, 砂原俊彦, 濱野真二郎
    • Organizer
      日本寄生虫学会南日本支部大会 ・ 第65回日本衛生動物学会南日本支部大会
    • Place of Presentation
      ポンぺ会館(長崎県)
    • Year and Date
      2015-10-17
    • Related Report
      2015 Annual Research Report
  • [Presentation] Epidemiology of S. haematobium and hookworm infections in Kwale, south coast Kenya2015

    • Author(s)
      Evans Chadeka, Sachiyo Nagi , Toshihiko Sunahara and Shinjiro Hamano
    • Organizer
      日本寄生虫学会南日本支部大会 ・ 第65回日本衛生動物学会南日本支部大会
    • Place of Presentation
      ポンぺ会館(長崎県)
    • Year and Date
      2015-10-17
    • Related Report
      2015 Annual Research Report
  • [Presentation] Intensity and associated factors of Schistoma haematobium and hookworm infections among school children in Kwale,south coast Kenya2015

    • Author(s)
      Evans Chadeka, Sachiyo Nagi , Toshihiko Sunahara and Shinjiro Hamano
    • Organizer
      14th Awaji International Forum on Infection and Immunity
    • Place of Presentation
      Awaji Yumebutai International Conference Center(兵庫県)
    • Year and Date
      2015-09-08
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] LAMP法を用いたケニア国ビタ県における中間宿主貝Biomphalaria sp.のマンソン住血吸虫感染率の評価2015

    • Author(s)
      菊池三穂子, 二見恭子, 凪幸世, Chadeka Evans A., Amulundu Maurice K., Bao Lam Q., 原史絵, 皆川昇, 平山謙二, 一瀬休生, 濱野真二郎
    • Organizer
      第84回日本寄生虫学会
    • Place of Presentation
      杏林大学(東京)
    • Year and Date
      2015-03-21 – 2015-03-22
    • Related Report
      2014 Annual Research Report
  • [Presentation] 西ケニアビタ地域における住血吸虫症とマラリアの空間分布2015

    • Author(s)
      凪幸世, Evans Chadeka, Benard Ngetich, Sammy Njenga, 濱野真二郎
    • Organizer
      第84回日本寄生虫学会
    • Place of Presentation
      杏林大学(東京)
    • Year and Date
      2015-03-21 – 2015-03-22
    • Related Report
      2014 Annual Research Report
  • [Presentation] ケニア国西部州における井戸建設が貧困地域の住民の水利用、疾病および衛生行動に与えた影響に関する研究2014

    • Author(s)
      崎坂香屋子, Evans Chadeka, 凪幸世, Dorcas Shambi, 神馬征峰
    • Organizer
      第55回日本熱帯医学会大会, 第29回日本国際保健医療学会学術大会
    • Place of Presentation
      東京女子医科大学、国立国際医療研究センター(東京)
    • Year and Date
      2014-11-01 – 2014-11-03
    • Related Report
      2014 Annual Research Report
  • [Presentation] Effect of co-infection with Schistosoma mansoni and Plasmodium falciparum on biochemical markers of children residing in endemic area2014

    • Author(s)
      Sachiyo Nagi, Evans Chadeka, Toshihiko Sunahara and Shinjiro Hamano
    • Organizer
      英国熱帯医学会
    • Place of Presentation
      Oxford Town Hall (オックスフォード、英国)
    • Year and Date
      2014-09-25
    • Related Report
      2014 Annual Research Report
  • [Remarks] 長崎大学熱帯医学研究所寄生虫学分野

    • URL

      http://www.tm.nagasaki-u.ac.jp/parasitology/html/paper.html

    • Related Report
      2014 Annual Research Report

URL: 

Published: 2015-01-22   Modified: 2024-03-26  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi