• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Regulation of Immune responses and autoimmune diseases by cytokines

Research Project

Project/Area Number 15002008
Research Category

Grant-in-Aid for Specially Promoted Research

Allocation TypeSingle-year Grants
Review Section Biological Sciences
Research InstitutionOsaka University

Principal Investigator

HIRANO Toshio  Osaka University, Graduate School of Frontier Biosciences, Professor (40136718)

Co-Investigator(Kenkyū-buntansha) MURAKAMI Masaaki  Osaka University, Graduate School of Frontier Biosciences, Associate Professor (00250514)
YAMASHITA Susumu  Osaka University, Graduate School of Frontier Biosciences, Assistant Professor (90346148)
石原 克彦  大阪大学, 生命機能研究科, 助教授 (10263245)
Project Period (FY) 2003 – 2007
Project Status Completed (Fiscal Year 2007)
Budget Amount *help
¥594,100,000 (Direct Cost: ¥457,000,000、Indirect Cost: ¥137,100,000)
Fiscal Year 2007: ¥81,900,000 (Direct Cost: ¥63,000,000、Indirect Cost: ¥18,900,000)
Fiscal Year 2006: ¥93,600,000 (Direct Cost: ¥72,000,000、Indirect Cost: ¥21,600,000)
Fiscal Year 2005: ¥93,600,000 (Direct Cost: ¥72,000,000、Indirect Cost: ¥21,600,000)
Fiscal Year 2004: ¥166,400,000 (Direct Cost: ¥128,000,000、Indirect Cost: ¥38,400,000)
Fiscal Year 2003: ¥158,600,000 (Direct Cost: ¥122,000,000、Indirect Cost: ¥36,600,000)
Keywordsmemory T cells / cytokine / homeostatic proliferation of T cells / Zinc / intracellular signaling / second messenger / メモリー T 細胞 / T 細胞の恒常的な増殖 / IL-6 / GP130 / STAT3 / 免疫 / 細胞運動 / 樹状細胞 / T細胞 / gp130 / 自己免疫疾患
Research Abstract

Our aim of this study was to know how Y759F mutation in gp130, an IL-6 signal transducer, induces an autoimmune arthritis disease in vivo and to investigate a role of IL-6-mediated signaling in the normal immune responses. We obtained two important concepts showing how tissue specific autoimmune diseases are induced as described below.
(1) Excess IL-7 expression induced by activation of non-hematopoietic cells via an excess IL-6 signaling triggers an excess homeostatic proliferation of CD4+ T cells followed by the development of autoimmune arthritis in F759 mice. We demonstrated how a dysregulated interaction between non-hematopoietic cells and hematopoietic cells, CD4+ T cells, induces a tissue specific autoimmune diseases in vivo.
(2) There is an IL-17-mediated IL-6 positive feedback loop in non-hematopoietic cells even in normal condition in vivo. Dysregulation of the IL-6 loop by a genetic abnormality such as Y759F mutation in F759 mice induces an excess production of IL-6 via the loop followed by the development of autoimmune arthritis.
Moreover, we proved the existence of intracellular Zinc signaling, which is also important for regulation of immune cell functions.

Report

(9 results)
  • 2013 Self-evaluation (Follow-up Assessment) ( PDF )   Comments (Follow-up Assessment) ( PDF )
  • 2012 Abstract(Follow-up Assessment) ( PDF )
  • 2007 Annual Research Report   Final Research Report Summary
  • 2006 Annual Research Report
  • 2005 Annual Research Report
  • 2004 Annual Research Report
  • 2003 Annual Research Report
  • Research Products

    (317 results)

All 2008 2007 2006 2005 2004 2003 Other

All Journal Article (114 results) (of which Peer Reviewed: 45 results) Presentation (185 results) Book (8 results) Remarks (2 results) Patent(Industrial Property Rights) (3 results) Publications (5 results)

  • [Journal Article] Combination treatment with IL-2 and anti-iL-2 mAbs reduces tumor metastasis via NK cell activation.2008

    • Author(s)
      Jin, G., et al.
    • Journal Title

      International Immunology (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] intracellular Zinc homeostasis and Zinc signaling.2008

    • Author(s)
      Murakami M., T. Hirano.
    • Journal Title

      Cancer Science (in press)

    • NAID

      10024009265

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Roles of Zinc and Zinc signaling in immunity : Zinc is an intracellular signaling molecule.2008

    • Author(s)
      T. Hirano, et al.
    • Journal Title

      Adavanced Immunology (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Combination treatment with IL-2 and anti-IL-2 mAbs reduces tumor metastasis via NK cell activation.2008

    • Author(s)
      Jin, G., T. Hirano, M. Murakami.
    • Journal Title

      International Immunology (in press)

    • NAID

      10021241636

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Intracellular Zinc homeostasis and Zinc signaling.2008

    • Author(s)
      Murakami, M., T. Hirano.
    • Journal Title

      Cancer Science (in press)

    • NAID

      10024009265

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Roles of Zinc and Zinc signaling in immunity : Zinc is an intracellular signaling molecule.2008

    • Author(s)
      Hirano, T.
    • Journal Title

      Adavanced Immunology (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Zinc and its transporter ZIPIO are involved in invasive behavior of breast cancer cells.2007

    • Author(s)
      Kagara, N., et al.
    • Journal Title

      Cancer Science 98

      Pages: 692-697

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] An essential role for RasGRP1 in mast cell function and IgE-mediated allergic response.2007

    • Author(s)
      Liu, Y., et al.
    • Journal Title

      J. Exp. Med. 204

      Pages: 93-103

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Homeostatic proliferating CD4 T cells are involved in the pathogenesis of an Omenn syndrome murine model.2007

    • Author(s)
      *Khiong, K., et al.
    • Journal Title

      J. Clin. Invest. 17

      Pages: 1270-1281

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Zinc is a novel intracellular second messenger.2007

    • Author(s)
      Yamasaki, S., et al.
    • Journal Title

      J. Cell Bio1. 177

      Pages: 637-645

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Epidermal Growth factor signaling mediated by Grb2 associated binder is required for the spatiotemporally regulated proliferation of Olig2-expressing progenitors in the embryonic spinal cord.2007

    • Author(s)
      Hayakawa-Yano, Y., et al.
    • Journal Title

      Stem Cells 25

      Pages: 1410-1422

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] IL-6-gpl30-STAT3 in T cells directs the development of IL-17+Thelper cells with a minimum effect on that of Treg in the steady state.2007

    • Author(s)
      Nishihara, M., et al.
    • Journal Title

      Int. Immunol. 19

      Pages: 695-702

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Gab family proteins are essential for postnatal maintenance of cardiac function via neuregulin-1/ErbB signaling.2007

    • Author(s)
      Nakaoka, Y., et al.
    • Journal Title

      J. Clinical Investigation : 117

      Pages: 1771-1781

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Zinc and its transporter ZIP10 are involved in invasive behavior of breast cancer cells.2007

    • Author(s)
      Kagara, N.
    • Journal Title

      Cancer Science. 98

      Pages: 692-697

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] An essential role for RasGRP1 in mast cell function and IgE-mediated allergic response.2007

    • Author(s)
      Liu, Y.
    • Journal Title

      J. Exp. Med. 204

      Pages: 93-103

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Homeostatic proliferating CD4 T cells are involved in the pathogenesis of an Omenn syndrome murine model.2007

    • Author(s)
      *Khiong, K. (*equal contribution)
    • Journal Title

      J. Clin. Invest. 17

      Pages: 1270-1281

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Zinc is a novel intracellular second messenger.2007

    • Author(s)
      Yamasaki, S.
    • Journal Title

      J. Cell Biol. 177

      Pages: 637-645

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Epidermal Growth factor signaling mediated by Grb2 associated binder is required for the spatiotemporally regulated proliferation of 0lig2-expressing progenitors in the embryonic spinal cord.2007

    • Author(s)
      Hayakawa-Yano, Y.
    • Journal Title

      Stem Cells 25

      Pages: 1410-1422

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] IL-6-gp130-STAT3 in T cells directs the development of IL-17+T helper cells with a minimum effect on that of Treg in the steady state.2007

    • Author(s)
      Nishihara, M.
    • Journal Title

      Int. Immunol. 19

      Pages: 695-702

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Gab family proteins are essential for postnatal maintenance of cardiac function via neuregulin-1/ErbB signaling.2007

    • Author(s)
      Nakaoka, Y.
    • Journal Title

      J. Clinical Investigation 117

      Pages: 1771-1781

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Zinc and its transporter ZIP10 are involved in invasive behavior of breast cancer cells.2007

    • Author(s)
      Kagara, N.・N., Tanaka・S., Noguchi・ and T., Hirano.
    • Journal Title

      Cancer Science 98

      Pages: 692-697

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] An essential role for RasGRP1 in mast cell function and IgE-mediated allergic response.2007

    • Author(s)
      Liu, Y.・M., Zhu・K., Nishida・T., Hirano・W., Zhang.
    • Journal Title

      J. Exp. Med. 204

      Pages: 93-103

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Homeostatic proliferating CD4 T cells are involved in the pathogenesi s of an Omenn syndrome murine model.2007

    • Author(s)
      Khiong, K.・*M., Murakami, et. al.
    • Journal Title

      J., Clin. Invest. 17

      Pages: 1270-1281

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Zinc is a novel intracelllular second messenger.2007

    • Author(s)
      Yamasaki, S., et. al.
    • Journal Title

      J., Cell Biol. 177

      Pages: 637-645

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Epidermal growth factor signaling mediated by Grb2 associated binder 1 is required for the spatiotemporally retulated proliferation of olig2-expressing progenitors in the embryonic spinal cord.2007

    • Author(s)
      Hayakawa-Yano, et. al.
    • Journal Title

      Stem Cells 25

      Pages: 1410-1422

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] IL-6-gp130-STAT3 in Tcells directs the development of IL-17+T helper cells with a minimum effect on that of Treg in the steady state.2007

    • Author(s)
      Nishihara, M., et. al.
    • Journal Title

      Int. Immunol. 19

      Pages: 695-702

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Gab family proteins are essential for postnatal maintenance of cardiac function bvia neuregulin-1/ErbB signaling.2007

    • Author(s)
      Nakaoka, Y., et. al.
    • Journal Title

      J. Clinical Investigation 117

      Pages: 1771-1781

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Homeostatic proliferating CD4 T cells are involved in the pathogenesis of an Omenn syndrome murine model.2007

    • Author(s)
      Khiong, K., M.Murakami, K.Ishihara, T.Hirano, et al.
    • Journal Title

      J. Clin. Invest (in press)

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Zinc and its transporter ZIP1O are involved in invasive behavior of breast cancer cells.2007

    • Author(s)
      Kagara, N., N.Tanaka, S.Noguchi, T.Hirano.
    • Journal Title

      Cnacer Science (in press)

    • Related Report
      2006 Annual Research Report
  • [Journal Article] A critical role for interleukin-6 family-mediated Stat3 activation on osteoblast differentiation and bone formation.2006

    • Author(s)
      Itoh, S., et al.
    • Journal Title

      Bone 39

      Pages: 505-512

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Autoimmune arthritis associated with mutated IL-6 receptor gp130 is driven by STAT3/IL-7-dependent homeostatic proliferation of CD4+T.2006

    • Author(s)
      Sawa, S., et al.
    • Journal Title

      J. Exp. Med. 203

      Pages: 1459-1470

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] IL-2 in vivo activities and anti-tumor efficacy enhanced by ananti-IL-2 mAb.2006

    • Author(s)
      Kamimura, D., et al.
    • Journal Title

      J. Immunol. 177

      Pages: 306-314

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Zinc is required for FceRI-mediated mast cell activation.2006

    • Author(s)
      Kabu, K., et al.
    • Journal Title

      J. Immunol. 177

      Pages: 1269-1305

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Toll-like receptor-mediated regulation of zinc homeostasis influences dendritic cell function.2006

    • Author(s)
      Kitamura, H., S. Yamashita, M. Murakami, T. Hirano, et al.
    • Journal Title

      Nature Immunol. 7

      Pages: 971-977

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] CD1d-restricted natural killer T cell activation enhanced homeostatic proliferation of CD8十T cells in a manner dependent onIL-4.2006

    • Author(s)
      Ueda, N., et al.
    • Journal Title

      Int. Immunol. 18

      Pages: 1397-1404

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] TRIF-GEFH1-RhoB cascade regulates surface expression of MHC classII in dendritic cells that is critical for CD4十T cell activation.2006

    • Author(s)
      Kamon, H., et al.
    • Journal Title

      EMBO J. 25

      Pages: 4108-4119

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Grasp a pTyr-peptide by its SOCS.2006

    • Author(s)
      Hirano, T., M. Murakami.
    • Journal Title

      Dev. Cell 10

      Pages: 542-544

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] A critical role for interleukin-6 family-mediated Stat3 activation on osteoblast differentiation and bone formation.2006

    • Author(s)
      Itoh, S.
    • Journal Title

      Bone 39

      Pages: 505-512

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Autoimmune arthritis associated with mutated IL-6 receptor gp130 is driven by STAT3/IL-7-dependent homeostatic proliferation of CD4+ T.2006

    • Author(s)
      Sawa, S.
    • Journal Title

      J. Exp. Med. 203

      Pages: 1459-1470

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Murakami. IL-2 in vivo activities and anti-tumor efficacy enhanced by an anti-IL-2 mAb.2006

    • Author(s)
      Kamimura, D.
    • Journal Title

      J. Immunol. 177

      Pages: 306-314

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Zinc is required for FceRI-mediated mast cell activation.2006

    • Author(s)
      Kabu, K.
    • Journal Title

      J. Immunol. 177

      Pages: 1296-1305

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Toll-like receptor-mediated regulation of zinc homeostasis influences dendritic cell function.2006

    • Author(s)
      Kitamura, H.
    • Journal Title

      Nature Immunol. 7

      Pages: 971-977

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] CD1d-restricted natural killer T cell activation enhanced homeostatic proliferation of CD8+T cells in a manner dependent on IL-4.2006

    • Author(s)
      Ueda, N.
    • Journal Title

      Int. Immunol. 18

      Pages: 1397-1404

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] TRIF-GEFH1-RhoB cascade regulates surface expression of MHC class II in dendritic cells that is critical for CD4+ T cell activation.2006

    • Author(s)
      Kamon, H.
    • Journal Title

      EMBO J. 25

      Pages: 4108-4119

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] TRIF-GEFH1-RhoB cascade regulates surface expression of MHC class II in dendritic cells that is critical for CD4+ T cell activation.2006

    • Author(s)
      Kamon, H., T.K.Ishihara, M., Murakami, T.Hirano, et al.
    • Journal Title

      EMBO J. 25

      Pages: 4108-4119

    • Related Report
      2006 Annual Research Report
  • [Journal Article] CD1d-restricted natural killer T cell activation enhanced homeostatic proliferation of CD8+T cells in a manner dependent on IL-4.2006

    • Author(s)
      Ueda, N., T.Hirano, M.Murakami, et al.
    • Journal Title

      Int. Immunol. 18

      Pages: 1397-1404

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Toll-like receptor-mediated regulation of zinc homeostasis influences dendritic cell function.2006

    • Author(s)
      Kitamura, H., S.Yamashita, M.Murakami, T.Hirano, et al.
    • Journal Title

      Nature Immunol. 7

      Pages: 971-977

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Zinc is required for FceRI-mediated mast cell activation.2006

    • Author(s)
      Kabu, K, T.Hirano, et al.
    • Journal Title

      J. Immunol. 177

      Pages: 1296-1305

    • Related Report
      2006 Annual Research Report
  • [Journal Article] IL-2 in vivo activities and anti-tumor efficacy enhanced by an anti-IL-2 mAb.2006

    • Author(s)
      Kamimura, D., T.Hirano, M.Murakami, et al.
    • Journal Title

      J. Immunol. 177

      Pages: 306-314

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Autoimmune arthritis associated with mutated IL-6 receptor gp130 is driven by STAT3/IL-7-dependent homeostatic proliferation of CD4+ T.2006

    • Author(s)
      Sawa, S., Ishihara, M.Murakami, T.Hirano, et al.
    • Journal Title

      J. Exp. Med. 203

      Pages: 1459-1470

    • Related Report
      2006 Annual Research Report
  • [Journal Article] FcεRI-mediated mast cell degranulation requires calcium-independent microtubule-dependent translocation of granules to the plasma membrane.2005

    • Author(s)
      Nishida, K., et al.
    • Journal Title

      J. Cell Biol. 170

      Pages: 115-126

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] IL-6-STAT3 controls intracellular MHC classII αβ-dimer level through Cathepsin S activity in dendritic cells.2005

    • Author(s)
      Kitamura, H., et al.
    • Journal Title

      Immunity 23

      Pages: 491-502

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] FceRI-mediated mast cell degranulation requires calcium-independent microtubule-dependent translocation of granules to the plasma membrane.2005

    • Author(s)
      Nishida, K.
    • Journal Title

      J. Cell Biol. 170

      Pages: 115-126

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] IL-6-STAT3 controls intracellular MHC classII α β-dimer level through Cathepsin S activity in dendritic cells.2005

    • Author(s)
      Kitamura, H.
    • Journal Title

      Immunity 23

      Pages: 491-502

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] IL-6-STAT3 controls intracellular MHC classII αβ-dimer level through Cathepsin S activity in dendritic cells.2005

    • Author(s)
      Kitamura, H., T.Hirano, et al.
    • Journal Title

      Immunity 23

      Pages: 491-502

    • Related Report
      2005 Annual Research Report
  • [Journal Article] FcεRI-mediated mast cell degranulation requires calcium-independent microtubule-dependent translocation of granules to the plasma membrane.2005

    • Author(s)
      Nishida, K., T.Hirano, et al.
    • Journal Title

      J.Cell Biol. 170

      Pages: 115-126

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Gabl contributes to cytoskeletal reorganization and chemotaxis in response to platelet-derived growth factor.2004

    • Author(s)
      Kallin, A., et al.
    • Journal Title

      J. Blol. Chem. 279

      Pages: 17897-17904

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] The point mutation of Y759 of the IL-6 family receptor gpl30synergizes with HTLV-1 pX in promoting RA-like arthritis.2004

    • Author(s)
      Ishihara, K., et al.
    • Journal Title

      Int. Immunol. 16

      Pages: 455-465

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Zinc transporter LIV1 controls epithelial-mesenchymal transition in zebrafish gastrula organizer.2004

    • Author(s)
      Yamashita, S., et al.
    • Journal Title

      Nature 429

      Pages: 298-302

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Genetic evidence for involvement of maternally derived Wnt canonical signaling in dorsal determination in zebrafish.2004

    • Author(s)
      Nojima, H., et al.
    • Journal Title

      Mech. Dev. 121

      Pages: 371-386

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Expression of sax1/nkx1. 2 and sax2/nkx1.1 in zebrafish.2004

    • Author(s)
      Bae, Y. -K., et al.
    • Journal Title

      Gene Expr. Patterns 4

      Pages: 481-486

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Zinc finger gene fez-like functions in the formation of subplate neurons and thalamocortical axons.2004

    • Author(s)
      Hirata, T., et al.
    • Journal Title

      Dev. Dyn. 230

      Pages: 546-556

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Downregulation of STAT3 activation is required for presumptive rod photoreceptor cells to differentiate in the postnatal retina.2004

    • Author(s)
      Ozawa, Y., et al.
    • Journal Title

      Mol. Cell Neurosci. 26

      Pages: 258-270

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Roles of MITF for Development of Mast Cells in Mice : Effects on Both Precursors and Tissue Environments.2004

    • Author(s)
      Morii, E., T. Hirano, et al.
    • Journal Title

      Blood 104

      Pages: 1656-1661

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] IL-6 Regulates in vivo Dendritic Cell Differentiation through STAT3 Activation.2004

    • Author(s)
      Park, S. -J., et al.
    • Journal Title

      J. Immunol. 173

      Pages: 3844-3854

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] STAT3 non-eel1-autonomously controls planner cell polarity during zebrafish convergence and extention.2004

    • Author(s)
      Miyagi, C., et al.
    • Journal Title

      J. Cell Biol. 166

      Pages: 975-981

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Koyasu, A. Miyajima. Development of CD4+ Macrophages from Intrathymic T Cell Progenitors Is Induced by Thymic Epithelial Cells.2004

    • Author(s)
      Esashi E., et al.
    • Journal Title

      J Immunol. 173

      Pages: 4360-4367

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Evidence of a novel IL-2/15Rbeta-targeted cytokine involved in homeostatic proliferation of memory CD8+T cells.2004

    • Author(s)
      Kamimura, D., et al.
    • Journal Title

      J. Immunol. 173

      Pages: 6041-6049

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Related Articles, Links. Tyrosine dephosphorylation of STAT3in SARS coronavirus-infected Vero E6 cells.2004

    • Author(s)
      Mizutani, T., et al.
    • Journal Title

      FEBS Lett. 5

      Pages: 187-192

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] New IL-6 (gpl30)family cytokine members, CLC/NNT1/BSF3 and IL27.2004

    • Author(s)
      Murakami, M, et al.
    • Journal Title

      Growth Factors 22

      Pages: 75-77

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Zinc transporter LIV1 controls epithelial-mesenchymal transition in zebrafish gastrula organizer.2004

    • Author(s)
      Yamashita, S.
    • Journal Title

      Nature 429

      Pages: 298-302

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Gab1 contributes to cytoskeletal reorganization and chemotaxis in response to platelet-derived growth factor.2004

    • Author(s)
      Kallin, A.
    • Journal Title

      J Biol Chem. 279

      Pages: 17897-17904

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] The point mutation of Y759 of the IL-6 family receptor gp130 synergizes with HTLV-1 pX in promoting RA-like arthritis.2004

    • Author(s)
      Ishihara, K.
    • Journal Title

      Int. Immunol. 16

      Pages: 455-465

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Genetic evidence for involvement of maternally derived Wnt canonical signaling in dorsal determination in zebrafish.2004

    • Author(s)
      Nojima, H.
    • Journal Title

      Mech. Dev. 121

      Pages: 371-86

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Expression of sax1/nkx1. 2 and sax2/nkx1. 1 in zebrafish.2004

    • Author(s)
      Bae, Y. -K.
    • Journal Title

      Gene Expr. Patterns. 4

      Pages: 481-6

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Zinc finger gene fez-like functions in the formation of subplate neurons and thalamocortical axons.2004

    • Author(s)
      Hirata, T.
    • Journal Title

      Dev. Dyn. 230

      Pages: 546-56

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Downregulation of STAT3 activation is required for presumptive rod photoreceptor cells to differentiate in the postnatal retina.2004

    • Author(s)
      Ozawa, Y.
    • Journal Title

      Mol. Cell Neurosci. 26

      Pages: 258-70

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Roles of MITF for Development of Mast Cells in Mice : Effects on Both Precursors and Tissue Environments.2004

    • Author(s)
      Morii, E.
    • Journal Title

      Blood. 104

      Pages: 1656-1661

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] IL-6 Regulates in vivo Dendritic Cell Differentiation through STAT3 Activation.2004

    • Author(s)
      Park, S. -J.
    • Journal Title

      J. Immunol. 173

      Pages: 3844-3854

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] STAT3 non-cell-autonomously controls planner cell polarity during zebrafish convergence and extention.2004

    • Author(s)
      Miyagi, C.
    • Journal Title

      J. Cell Biol. 166

      Pages: 975-981

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Development of CD4+ Macrophages from Intrathymic T Cell Progenitors Is Induced by Thymic Epithelial Cells.2004

    • Author(s)
      Esashi E
    • Journal Title

      J Immunol. 173

      Pages: 4360-4367

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Evidence of a novel IL-2/15Rbeta-targeted cytokine involved in homeostatic proliferation of memory CD8+ T cells.2004

    • Author(s)
      Kamimura, D.
    • Journal Title

      J. Immunol. 173

      Pages: 6041-6049

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Related Articles, Links. Tyrosine dephosphorylation of STAT3 in SARS coronavirus-infected Vero E6 cells.2004

    • Author(s)
      Mizutani T
    • Journal Title

      FEBS Lett. 5 ; 577 (1-2)

      Pages: 187-192

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Interleukin-6 edited by Martini, L., Academic Press2004

    • Author(s)
      Ohtani, T., T. Hirano.
    • Journal Title

      Encyclopedia of Endocrinology and Endocrine Diseases

      Pages: 64-70

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] New IL-6 (gp130) family cytokine members, CLC/NNT1/BSF3 and IL-27.2004

    • Author(s)
      Murakami, M., D. Kamimura, T. Hirano.
    • Journal Title

      Growth Facotrs 22

      Pages: 75-77

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Gab1 contributes to cytoskeletal reorganization and chemotaxis in response to platelet-derived growth factor.2004

    • Author(s)
      Kallin, A., T.Hirano, et al.
    • Journal Title

      J.Biol.Chem. 279

      Pages: 17897-17904

    • Related Report
      2004 Annual Research Report
  • [Journal Article] The point mutation of Y759 of the IL-6 family receptor gp130 synergizes with HTLV-1 pX in promoting RA-like arth2004

    • Author(s)
      Ishihara, K., T.Hirano, et al.
    • Journal Title

      Int.Immunol. 16

      Pages: 455-465

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Zinc transporter LIV1 controls epithelial-mesenchymal transition in zebrafish gastrula organizer.2004

    • Author(s)
      Yamashita, S., T.Hirano, et al.
    • Journal Title

      Nature 429

      Pages: 298-302

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Genetic evidence for involvement of maternally derived Wnt canonical signaling in dorsal determination in zebrafish.2004

    • Author(s)
      Nojima, H., T.Hirano, et al.
    • Journal Title

      Mech.Dev. 121

      Pages: 371-386

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Expression of sax1/nkx1.2 and sax2/nkx1.1 in zebrafish.2004

    • Author(s)
      Bae, Y.-K., T.Hirano, et al.
    • Journal Title

      Gene Expr.Patterns 4

      Pages: 481-486

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Zinc finger gene fez-like functions in the formation of subplate neurons and thalamocortical axons.2004

    • Author(s)
      Hirata, T., T.Hirano, et al.
    • Journal Title

      Dev.Dyn. 230

      Pages: 546-556

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Downregulation of STAT3 activation is required for presumptive rod photoreceptor cells to differentiate in the postnatal retina.2004

    • Author(s)
      Ozawa, Y., T.Hirano, et al.
    • Journal Title

      Mol.Cell.Neurosci. 26

      Pages: 258-270

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Roles of MITF for Development of Mast Cells in Mice : Effects on Both Precursors and Tissue Environments.2004

    • Author(s)
      Morii, E., T.Hirano, et al.
    • Journal Title

      Blood 104

      Pages: 1656-1661

    • Related Report
      2004 Annual Research Report
  • [Journal Article] L-6 Regulates in vivo Dendritic Cell Differentiation through STAT3 Activation.2004

    • Author(s)
      Park, S.-J., T.Hirano, et al.
    • Journal Title

      J.Immunol. 173

      Pages: 3844-3854

    • Related Report
      2004 Annual Research Report
  • [Journal Article] STAT3 non-cell-autonomously controls planner cell polarity during zebrafish convergence and extention.2004

    • Author(s)
      Miyagi, C., T.Hirano, et al.
    • Journal Title

      J.Cell Biol. 166

      Pages: 975-981

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Koyasu, A.Miyajima. Development of CD4+ Macrophages from Intrathymic T Cell Progenitors Is Induced by Thymic Epithelial Cell2004

    • Author(s)
      Esashi E, T.Hirano, et al.
    • Journal Title

      J Immunol. 173

      Pages: 4360-4367

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Evidence of a novel IL-2/15Rbeta-targeted cytokine involved in homeostatic proliferation of memory CD8+ T cells.2004

    • Author(s)
      Kamimura, D., T.Hirano, et al.
    • Journal Title

      J.Immunol. 173

      Pages: 6041-6049

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Gads/Grb2-mediated association with LAT is critical for the inhibitory function of Gab2 in T cells.2003

    • Author(s)
      Yamasaki S, et al.
    • Journal Title

      Mol Cell Biol. 23

      Pages: 2515-2529

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Gabl is required for EGF receptor signaling and the transformation by activated ErbB2.2003

    • Author(s)
      Yamasaki, S., et al.
    • Journal Title

      Oncogene 13

      Pages: 1546-1556

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] A homeobox gene, pnx, is involved in the formation of posterior neurons in zebrafish2003

    • Author(s)
      Bae YK, et al.
    • Journal Title

      Development 130

      Pages: 1853-1865

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Ogon/Secreted Frizzled functions as a negative feedback regulator of Bmp signaling.2003

    • Author(s)
      Yabe T, et al.
    • Journal Title

      Development 130

      Pages: 2705-2716

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] IL-6 induces an anti-inflammatory response in the absence of S0CS3in macrophages.2003

    • Author(s)
      Yasukawa, H., et al.
    • Journal Title

      Nature Immunology 4

      Pages: 551-556

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Activation of gpl30 Transduces Hypertrophic Signal through Interaction of Scaffolding/Docking Protein Gabl with Tyrosine Phosphatase SHP2 in Cardiomyocytes2003

    • Author(s)
      Nakaoka, Y., et al.
    • Journal Title

      Circulation Research 93

      Pages: 221-229

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] The role of Gab family scaffolding adapter proteins in the signal transduction of cytokine and growth factor receptors.2003

    • Author(s)
      Nishida, K., T. Hirano.
    • Journal Title

      Cancer Science 94

      Pages: 1029-1033

    • NAID

      10012163848

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Gads/Grb2-mediated association with LAT is critical for the inhibitory function of Gab2 in T cells.2003

    • Author(s)
      Yamasaki S
    • Journal Title

      Mol Cell Biol. 23

      Pages: 2515-2529

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Gab1 is required for EGF receptor signaling and the transformation by activated ErbB2.2003

    • Author(s)
      Yamasaki, S.
    • Journal Title

      Oncogene 13

      Pages: 1546-1556

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] A homeobox gene, pnx, is involved in the formation of posterior neurons in zebrafish.2003

    • Author(s)
      Bae YK
    • Journal Title

      Development 130

      Pages: 1853-1865

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Ogon/Secreted Frizzled functions as a negative feedback regulator of Bmp signaling.2003

    • Author(s)
      Yabe T
    • Journal Title

      Development. 130

      Pages: 2705-2716

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages.2003

    • Author(s)
      Yasukawa, H.
    • Journal Title

      Nature Immunology 4

      Pages: 551-556

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Activation of gp130 Transduces Hypertrophic Signal through Interaction of Scaffolding/Docking Protein Gab1 with Tyrosine Phosphatase SHP2 in Cardiomyocytes"2003

    • Author(s)
      Nakaoka, Y.
    • Journal Title

      Circulation Research 93

      Pages: 221-229

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] The role of Gab family scaffolding adapter proteins in the signal transduction of cytokine and growth factor receptors.2003

    • Author(s)
      Nishida, K.
    • Journal Title

      Cancer Science 94

      Pages: 1029-1033

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Interleukin-6, edited by Henry, H. L, and Norman, A. W. Academic Press2003

    • Author(s)
      Kamimura D., T. Hirano.
    • Journal Title

      Encyclopedia of Hormones

      Pages: 430-439

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] IL-6 signal transduction and its physiological roles : The signal orchestration model.2003

    • Author(s)
      Kamimura, D., K. Ishihara, T. Hirano.
    • Journal Title

      Reviews of Physiology, Biochemistry and Pharmacology 149

      Pages: 1-38

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Mechanisms and biological roles of STAT activation by the IL-6 family of cytokines. edited by P. B. Sehgal, D. E. Levy and T. Hirano, Kluwer Academic Publishers2003

    • Author(s)
      Kamimura, D., T. Hirano.
    • Journal Title

      Signal Transducers and Activators of Transcription (STATs) : Activation and Biology

      Pages: 595-607

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 細胞内亜鉛信号による細胞活性化の制御2008

    • Author(s)
      村上正晃
    • Organizer
      日本薬学会第128年会
    • Place of Presentation
      パシフィコ横浜、横浜みなとみらいホール
    • Year and Date
      2008-03-27
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Regulation of cell activation by intracellular zinc signaling.2008

    • Author(s)
      Murakami, M.
    • Organizer
      The 128^<th> Annual Meeting of the Pharmaceutical Society of Japan
    • Place of Presentation
      Pacifico Yokohama, Yokohama, Japan.
    • Year and Date
      2008-03-27
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 抗原提示におけるサイトカインIL-6とカテプシンの関係2008

    • Author(s)
      村上正晃
    • Organizer
      徳島文理大学・健康科学研究所・私学助成研究発表会
    • Place of Presentation
      徳島文理大学・山城校
    • Year and Date
      2008-01-26
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Relationship between IL-6 and Cathepsin in antigen presentation2008

    • Author(s)
      Murakami, M.
    • Organizer
      Institute for Health Sciences, Tokushima Bunri University, Tokushima Bunri University, Institute for Health Sciences, Private school promotion research symposium
    • Place of Presentation
      Tokushima Bunri University, Japan.
    • Year and Date
      2008-01-26
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Roles of zinc and zinc signaling in immune response2008

    • Author(s)
      平野俊夫
    • Organizer
      免疫フロンティア研究センターシンポジウム
    • Place of Presentation
      大阪国際会議場
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Roles of zinc and zinc signaling in immune response2008

    • Author(s)
      Hirano, T.
    • Organizer
      Kick-off symposium of WPI IFReC - Immunology and Imaging-
    • Place of Presentation
      Osaka International Convention Center, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Mechanism of disruption of homeostatic proliferation of CD4+T cells and by cytokine signaling.2007

    • Author(s)
      Murakami, M.
    • Organizer
      The 28^<th> Science Meeting of Department of Veterinary of Hokkaido University. “The front of immunology-The future of immunology for young scientists"
    • Place of Presentation
      Learning exchange hall of Hokkaido University, Japan.
    • Year and Date
      2007-12-18
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 網羅的に分子の挙動を捉える技術-cDNAや抗体というリソースを活用した新しい2007

    • Author(s)
      村上正晃
    • Organizer
      BMB2007(第30回日本分子生物学会年会・第80回日本生化学会大会 合同大会)
    • Place of Presentation
      パシフィコ横浜・ヨコハマグランドインターコンチネンタルホテル
    • Year and Date
      2007-12-11
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] A new technique for capturing the motility of molecules thoroughly-Utilizing the resources such as cDNA and antibody.2007

    • Author(s)
      Murakami, M.
    • Organizer
      BMB2007(The 30^<th> Annual Meeting of the Molecular Biology Society of Japan, The 80^<th> Annual Meeting of the Japanese Biochemical Society)
    • Place of Presentation
      Pacifico Yokohama, and Yokohama Grand Intercontinental Hotel, Yokohama, Japan.
    • Year and Date
      2007-12-11
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Zinc signaling in dendritic cells2007

    • Author(s)
      村上正晃
    • Organizer
      The 20^<th> Naito Conference on Innate Immunity in Medicine and Biology [III]
    • Place of Presentation
      Shonan Village Center, Kanagawa, Japan
    • Year and Date
      2007-10-11
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Zinc signaling in dendritic cells.2007

    • Author(s)
      Hirano, T.
    • Organizer
      The 20^<th> Naito Conference on Innate Immunity in Medicine and Biology [III], Shonan Village Center
    • Place of Presentation
      Kanagawa, Japan.
    • Year and Date
      2007-10-11
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 免疫応答における亜鉛の役割 : 亜鉛は新しいセカンドメッセンジャーである2007

    • Author(s)
      村上正晃
    • Organizer
      メクロチオンネインおよびメタルバイオサイエンス研究2007
    • Place of Presentation
      徳島県文理大学国際会議場
    • Year and Date
      2007-09-29
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Roles of zinc in immune response : Zinc is a new second messenger.2007

    • Author(s)
      Murakami, M.
    • Organizer
      Metallothionein and metalbioscience research 2007
    • Place of Presentation
      Tokushima Bunri University International Convention Center, Japan.
    • Year and Date
      2007-09-29
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 免疫にとっての自己とは? 非自己とは?2007

    • Author(s)
      平野俊夫
    • Organizer
      科学ゼミナール
    • Place of Presentation
      電力館(東京電力)
    • Year and Date
      2007-09-08
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] What is self, or non-self for immune system?2007

    • Author(s)
      Murakami, M.
    • Organizer
      Science Seminar
    • Place of Presentation
      Denryokukan, Japan.
    • Year and Date
      2007-09-08
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 免疫・アレルギーと亜鉛 : 亜鉛は細胞内シグナル伝達分子である2007

    • Author(s)
      平野俊夫
    • Organizer
      大阪消化器フォーラム 特別講演
    • Place of Presentation
      大阪
    • Year and Date
      2007-07-13
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Immunity, allergy, and zinc : Zinc is a new intracellular signal messenger2007

    • Author(s)
      Hirano, T.
    • Organizer
      Osaka digestion forum, Special lecture
    • Place of Presentation
      Osaka, Japan.
    • Year and Date
      2007-07-13
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Role of zinc and zinc signaling in immunity : Zn is an intracellular second messenger.2007

    • Author(s)
      平野俊夫
    • Organizer
      2007 International Mucosal Immunity. (第13回国際粘膜免疫学会イブニングセミナー)
    • Place of Presentation
      Shinagawa Prince Hotel, Tokyo
    • Year and Date
      2007-07-11
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Role of zinc and zinc signaling in immunity : Zn is an intracellular second messenger.2007

    • Author(s)
      Hirano, T.
    • Organizer
      2007 International Mucosal Immunity, Evening Seminar
    • Place of Presentation
      Shinagawa Prince Hotel, Tokyo, Japan.
    • Year and Date
      2007-07-11
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 亜鉛によるアレルギー・免疫制御2007

    • Author(s)
      平野俊夫
    • Organizer
      第12回「鼻アレルギー治療研究会」
    • Place of Presentation
      千里ライフサイエンスセンター
    • Year and Date
      2007-06-30
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Regulation of allergy and immune system by zinc2007

    • Author(s)
      Hirano, T.
    • Organizer
      The 12^<th> “The treatment society for nosal allergy"
    • Place of Presentation
      Senri Life Science Center, Japan.
    • Year and Date
      2007-06-30
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 亜鉛と免疫・アレルギー2007

    • Author(s)
      平野俊夫
    • Organizer
      第19回日本アレルギー学会春季臨床大会 特別プログラム
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2007-06-10
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Zinc and immunity_allergy2007

    • Author(s)
      Hirano, T.
    • Organizer
      The 19^<th> Spring Meeting of Japanese Society of Allergology, Special Program
    • Place of Presentation
      Pacifico Yokohama, Japan.
    • Year and Date
      2007-06-10
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 亜鉛シグナルは存在するか? : 亜鉛は新しいセカンドメッセンジャーである。2007

    • Author(s)
      平野俊夫
    • Organizer
      第24回日本微量元素研究会シンポジウム特別講演
    • Place of Presentation
      京都リサーチパーク
    • Year and Date
      2007-06-07
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Does Zinc signaling exist? : Zinc is a new second messenger.2007

    • Author(s)
      Hirano, T.
    • Organizer
      The 24^<th> Trace Nutrients Research Symposium, Special Lecture
    • Place of Presentation
      Kyoto Research Park, Japan.
    • Year and Date
      2007-06-07
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] サイトカインシグナル異常と自己免疫疾患2007

    • Author(s)
      平野俊夫
    • Organizer
      第27回日本医学会総会 特別講演
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2007-04-06
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Aberrant cytokine signaling and autoimmune disease.2007

    • Author(s)
      Hirano, T.
    • Organizer
      The 27^<th> General Assembly of The Japan Medical Congress, Special Lecture, Immune system and its disruption-For understanding higher complex immune system
    • Place of Presentation
      Osaka International Convention Center, Japan.
    • Year and Date
      2007-04-06
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Zinc and interleukin 6 signaling in immune responses : Zn2+is a novel intracellular second messenger2007

    • Author(s)
      平野俊夫
    • Organizer
      高津先生退官記念シンポジウム
    • Place of Presentation
      東京大学医科学研究所講堂
    • Year and Date
      2007-03-23
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] From Interleukin-6 to Zinc Signaling in Immune Responses : Zn2+is a Novel Intracellular Second Messenger2007

    • Author(s)
      平野俊夫
    • Organizer
      International Symposium, Lymphocyte DecodingTheir Development and Function
    • Place of Presentation
      東京
    • Year and Date
      2007-03-23
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Zinc and interleukin-6 signaling in immune responses : Zn2+ is a novel intracellular second messenger2007

    • Author(s)
      Hirano, T.
    • Organizer
      Prof. Takatsu retirement commemoration symposium
    • Place of Presentation
      The Institute of Medical Science, The University of Tokyo, Japan.
    • Year and Date
      2007-03-23
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] From Interleukin-6 to Zinc Signaling in Immune Responses : Zn2+ is a Novel Intracellular Second Messenger2007

    • Author(s)
      Hirano, T.
    • Organizer
      International Symposium, Lymphocyte Decoding Their Development and Function
    • Place of Presentation
      Tokyo, Japan.
    • Year and Date
      2007-03-23
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] サイトカイン発現ネットワークと自己免疫疾患2007

    • Author(s)
      村上正晃
    • Organizer
      フロンティアバイオサイエンスコロキュウム生命機能研究科第27回研究交流会
    • Place of Presentation
      大阪大学生命機能研究科
    • Year and Date
      2007-03-14
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Cytokine expression network and autoimmune disease.2007

    • Author(s)
      Murakami, M.
    • Organizer
      27^<th> Frontier Bioscience Colloquium
    • Place of Presentation
      Graduate School of Frontier Biosciences, Osaka University, Japan.
    • Year and Date
      2007-03-14
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] IL-6-gpl30-STAT3 signaling plays roles in autoimmune disease through regulating T cell homeostatic proliferation and Thl7 development.2007

    • Author(s)
      平野俊夫
    • Organizer
      5th International Symposium on ″Cytokine signalling
    • Place of Presentation
      Aachen, Germany
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] IL-17 derived from homeostatic proliferating memory/activated CD4^+ T cells develops arthritis in F759 mice.2007

    • Author(s)
      村上正晃
    • Organizer
      The 37^<th>Annual Meeting of the Japanese Society for Immunology, International Symposium.
    • Place of Presentation
      Tokyo, Japan
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Antigen independent induction of a CD4+T cell-dependent arthritis.2007

    • Author(s)
      小椋英樹
    • Organizer
      第37回日本免疫学会総会・学術集会
    • Place of Presentation
      グランドプリンスホテル新高輪(東京都)
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Annual Research Report 2007 Final Research Report Summary
  • [Presentation] Liver acute-phase reactions convert innate immune signaling into adaptive immune responses2007

    • Author(s)
      澤 幸久
    • Organizer
      第37回日本免疫学会総会・学術集会
    • Place of Presentation
      グランドプリンスホテル新高輪(東京都)
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] IL-6 inhibits PLCg activation in TCR-mediated signaling2007

    • Author(s)
      佐藤優江
    • Organizer
      第37回日本免疫学会総会・学術集会
    • Place of Presentation
      グランドプリンスホテル新高輪(東京都)
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Annual Research Report 2007 Final Research Report Summary
  • [Presentation] NK cell-mediated inhibition of tumor metastasis by a combination treatment of IL-2 and anti-IL-2 antibody.2007

    • Author(s)
      金 桂花
    • Organizer
      第37回日本免疫学会総会・学術集会
    • Place of Presentation
      グランドプリンスホテル新高輪(東京都)
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Annual Research Report 2007 Final Research Report Summary
  • [Presentation] Zinc is an intracellular signaling molecule.2007

    • Author(s)
      平野俊夫
    • Organizer
      International Symposium on Metallomics 2007(ISM 2007). Keynote lecture
    • Place of Presentation
      Nagoya, Japan
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] IL-6-gp130-STAT3 signaling plays roles in autoimmune disease through regulating T cell homeostatic proliferation and Th17 development.2007

    • Author(s)
      Hirano, T.
    • Organizer
      5th International Symposium on "Cytokine signalling"
    • Place of Presentation
      Aachen, Germany.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] L-17 derived from homeostatic proliferating memory/activated CD4^+ T cells develops arthritis in F759 mice.2007

    • Author(s)
      Murakami, M.
    • Organizer
      The 37^<th> Annual Meeting of the Japanese Society for Immunology, International Symposium
    • Place of Presentation
      Tokyo, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Antigen independent induction of a CD4+ T cell-dependent arthritis.2007

    • Author(s)
      Ogura, H.
    • Organizer
      The 37^<th> Annual Meting of the Japanese Society for Immunology
    • Place of Presentation
      Grand Prince Hotel New Takanawa, Shinagawa, Tokyo, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Liver acute-phase reactions convert innate immune signaling into adaptive immune responses.2007

    • Author(s)
      Sawa, Y.
    • Organizer
      The 37^<th> Annual Meting of the Japanese Society for Immunology
    • Place of Presentation
      Grand Prince Hotel New Takanawa, Shinagawa, Tokyo, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] IL-6 inhibits PLCγ activation in TCR-mediated signaling.2007

    • Author(s)
      Sato, M.
    • Organizer
      The 37^<th> Annual Meting of the Japanese Society for Immunology
    • Place of Presentation
      Grand Prince Hotel New Takanawa, Shinagawa, Tokyo, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] NK cell-mediated inhibition of tumor metastasis by a combination treatment of IL-2 and anti-IL-2 antibody.2007

    • Author(s)
      Jin, G.
    • Organizer
      The 37^<th> Annual Meting of the Japanese Society for Immunology
    • Place of Presentation
      Grand Prince Hotel New Takanawa, Shinagawa, Tokyo, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Zinc is an intracellular signaling molecule.2007

    • Author(s)
      Hirano T.
    • Organizer
      ISM 2007(International Symposium on Metallomics 2007). Keynote lecture
    • Place of Presentation
      Nagoya, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Lliver acute-phase reactions convert innate immune signaling into adapive immune responses2007

    • Author(s)
      Yukihisa, Sawa
    • Organizer
      第37回日本免疫学会総会・学術集会
    • Place of Presentation
      グランドプリンスホテル新高輪(東京都)
    • Related Report
      2007 Annual Research Report
  • [Presentation] サイトカイン信号によるCD4T細胞の恒常性維持の破綻と免疫異常2006

    • Author(s)
      村上正晃
    • Organizer
      平成18年度(第28回)北海道大学獣医学学術交流基金群講演会「免疫学の最前線-若手研究者の考える免疫学の未来-」
    • Place of Presentation
      北海道大学学術交流会館
    • Year and Date
      2006-12-18
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 免疫にとっての自己とは? 非自己とは?2006

    • Author(s)
      平野俊夫
    • Organizer
      平成18年度千里ライフサイエンスフォーラム
    • Place of Presentation
      千里クラブ
    • Year and Date
      2006-10-27
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] What is self, or non-self for immune system?2006

    • Author(s)
      Hirano, T.
    • Organizer
      Fiscal 2006 Senri Life Science Form
    • Place of Presentation
      Senti Clab, Japan.
    • Year and Date
      2006-10-27
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] サイトカインシグナルから亜鉛シグナル研究へ : 免疫アレルギー・発生・がん研究の橋渡し2006

    • Author(s)
      平野俊夫
    • Organizer
      第86回北海道医学大会総会 特別講演
    • Place of Presentation
      札幌グランドホテル
    • Year and Date
      2006-09-30
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] From cytokine signaling to Zinc signaling : Bridge of the researches of immunity, embryo, and cancer.2006

    • Author(s)
      Hirano, T.
    • Organizer
      The 86^<th> Annual- Meeting of Hokkaido Medical Congress, Special Lecture
    • Place of Presentation
      Sapporo Grand Hotel, Japan.
    • Year and Date
      2006-09-30
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 免疫にとっての自己とは? 非自己とは?2006

    • Author(s)
      平野俊夫
    • Organizer
      天王寺高等学校スーパーサイエンススクール
    • Place of Presentation
      大阪国際交流センター大ホール
    • Year and Date
      2006-09-14
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] What is self, or non-self for immune system?2006

    • Author(s)
      Hirano, T.
    • Organizer
      Tennohji high school super science school
    • Place of Presentation
      International House, Osaka, Japan.
    • Year and Date
      2006-09-14
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 免疫、発生、がんにおけるサイトカイン・増殖因子シグナルと亜鉛 : 亜鉛はシグナル分子として作用しうるか?2006

    • Author(s)
      平野俊夫
    • Organizer
      第71回日本インターフェロンサイトカイ学会学術集会
    • Place of Presentation
      兵庫医科大学平成記念会館
    • Year and Date
      2006-07-08
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Cytokines, growth factors, and zinc for immunity, embryo, and cancer : Can zinc act as siganal molecule?2006

    • Author(s)
      Hirano, T.
    • Organizer
      The 71th Annual Meeting of The Japanese Society for Interferon and Cytokine Research
    • Place of Presentation
      Heisei memorial hall of Hyogo College of Medicine, Japan.
    • Year and Date
      2006-07-08
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] サイトカインシグナルから亜鉛シグナル研究へ : 免疫・発生・がん研究の橋渡し2006

    • Author(s)
      平野俊夫
    • Organizer
      第9回免疫ワークショップ学術集会
    • Place of Presentation
      芝蘭会館、京都
    • Year and Date
      2006-04-01
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] From cytokine signaling to Zinc signaling : Bridge of the researches of immunity, embryo, and cancer.2006

    • Author(s)
      Hirano, T.
    • Organizer
      The 9^<th> Science Meeting of immune workshop
    • Place of Presentation
      Shirankaikan, Japan.
    • Year and Date
      2006-04-01
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 新しいマスト細胞脱顆粒抑制剤の開発の可能性2006

    • Author(s)
      平野俊夫
    • Organizer
      花粉症研究シンポジウム-花粉症克服へ向けた最新研究動向-
    • Place of Presentation
      ヤクルトホール、東京都
    • Year and Date
      2006-01-17
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Potentiality for discovering new inhibitors of mast cell degranulation.2006

    • Author(s)
      Hirano, T.
    • Organizer
      Pollinosis research symposium-The latest research trend for overcoming pollinosis
    • Place of Presentation
      Yakult Hall, Japan.
    • Year and Date
      2006-01-17
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Fc ε RI-mediated mast cell degranulation requires calcium-independent microtubule-dependent translocation of granules to the plasma membrane : Zinc-dependent pathway2006

    • Author(s)
      平野俊夫
    • Organizer
      RCAI-JSI International Symposium on Immunology 2006
    • Place of Presentation
      Hamagin Hall Via Mare, Yokohama
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Zinc signaling regulates epithelial-mesenchymal transition and activation of immune cells : Zinc is a novel second messenger?2006

    • Author(s)
      平野俊夫
    • Organizer
      The Japan Society for Promotion of Scienceand the National Institutes of Heath are planning to hold the first joint symposium
    • Place of Presentation
      NIH Bethesda, U. S. A.
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Zinc signaling in epithelial-mesenchymal transition2006

    • Author(s)
      山下 晋
    • Organizer
      Fifth East Asian Biophysics Symposium & Forty-Fourth Annua1 Meeting of the Biophysical Society of Japan
    • Place of Presentation
      沖縄
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Zinc signaling regulates epithelial-mesenchymal transition.2006

    • Author(s)
      平野俊夫
    • Organizer
      The 37th International Symposium of the Princess Takamatsu Cancer Research Fund
    • Place of Presentation
      東京
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Roles of zinc in development, immunity and cancer : Does Zn function as a signaling molecule?2006

    • Author(s)
      平野俊夫
    • Organizer
      The Osaka University Forum in San Diego
    • Place of Presentation
      San Diego, U. S. A.
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Zinc and dendritic cell maturation : Does zinc act as a signaling molecule?2006

    • Author(s)
      平野俊夫
    • Organizer
      The 36^<th> Annual Meeting of the Japanese Society for Immunology, International Symposium
    • Place of Presentation
      大阪
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Non-hematopoietic cell populations play a role for IL-6-mediated enhancement of CD4 T cell activation.2006

    • Author(s)
      村上正晃
    • Organizer
      The 36^<th> Annual Meeting of the Japanese Society for Immunology, International Symposium
    • Place of Presentation
      大阪
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Critical role of TRIF-GEFH1-RhoB pathway for MHCII expression on dendritic cells.2006

    • Author(s)
      加門北斗
    • Organizer
      第36回日本免疫学会総会・学術集会
    • Place of Presentation
      大阪国際会議場
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Zinc has a role in dendritic cell maturation.2006

    • Author(s)
      守川英幸
    • Organizer
      第36回日本免疫学会総会・学術集会
    • Place of Presentation
      大阪国際会議場
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] A mutant mouse having excess amount of memory T cells is a model mouse of Omenn syndrome.2006

    • Author(s)
      キー・キョン
    • Organizer
      第36回日本免疫学会総会・学術集会
    • Place of Presentation
      大阪国際会議場
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] IL-2 functions increased by an anti-IL-2 mAb in vivo2006

    • Author(s)
      澤 幸久
    • Organizer
      第36回日本免疫学会総会・学術集会
    • Place of Presentation
      大阪国際会議場
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] IL-6/IL-6 family-STAT3-IL-7 cascade causes an autoimmune arthritis via CD4+T-cell homeostatic proliferation ingpl30^<F759/F759> mice.2006

    • Author(s)
      小椋英樹
    • Organizer
      第36回日本免疫学会総会・学術集会
    • Place of Presentation
      大阪国際会議場
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Involvement of STAT3 signaling for IL-6-mediated development ofIL-17 producing CD4 T cells.2006

    • Author(s)
      西原三佳
    • Organizer
      第36回日本免疫学会総会・学術集会
    • Place of Presentation
      大阪国際会議場
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] CD8 T cell homeostatic proliferation in vivo is regulated byIL-4 from NKT cells.2006

    • Author(s)
      植田尚子
    • Organizer
      第36回日本免疫学会総会・学術集会
    • Place of Presentation
      大阪国際会議場
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Fc ε RI-mediated mast cell degranulation requires calcium-independent microtubule-dependent translocation of granules to the plasma membrane : Zinc-dependent pathway.2006

    • Author(s)
      Hirano, T.
    • Organizer
      RCAI-JSI International Symposium on Immunology 2006, Regulation of Immune Responses in Allergy and Inflammation
    • Place of Presentation
      Hamagin Hall Via Mare, Yokohama, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Zinc signaling regulates epithelial-mesenchymal transition and activation of immune cells : Zinc is a novel second messenger?2006

    • Author(s)
      Hirano, T.
    • Organizer
      The Japan Society for Promotion of Science and the National Institutes of Heath are planning to hold the first joint symposium.
    • Place of Presentation
      NIH Bethesda, U.S.A.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Zinc signaling in epithelial-mesenchymal transition2006

    • Author(s)
      Yamashita, S.
    • Organizer
      Fifth East Asian Biophysics Symposium & Forty-Fourth Annual Meeting of the Biophysical Society of Japan.
    • Place of Presentation
      Okinawa, Japan
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Zinc signaling regulates epithelial-mesenchymal transition2006

    • Author(s)
      Hirano, T.
    • Organizer
      The 37th International Symposium of the Princess Takamatsu Cancer Research Fund "Cancer Micrioenviromnents"
    • Place of Presentation
      Tokyo, Japan
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Roles of zinc in development, immunity and cancer : Does Zn function as a signaling molecule?2006

    • Author(s)
      Hirano, T.
    • Organizer
      The Osaka University Forum in San Diego.
    • Place of Presentation
      San Diego, U.S.A.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Zinc and dendritic cell maturation : Does zinc act as a signaling molecule?2006

    • Author(s)
      Hirano, T.
    • Organizer
      The 36^<th> Annual Meeting of the Japanese Society for Immunology, International Symposium
    • Place of Presentation
      Osaka, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Non-hematopoietic cell populations play a role for IL-6-mediated enhancement of CD4 T cell activation.2006

    • Author(s)
      Murakami, M.
    • Organizer
      The 36^<th> Annual Meeting of the Japanese Society for Immunology, International Symposium
    • Place of Presentation
      Osaka, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Critical role of TRIF-GEFH1-RhoB pathway for MHCII expression on dendritic cells.2006

    • Author(s)
      Kamon, H.
    • Organizer
      The 36^<th> Annual Meting of the Japanese Society for Immunology
    • Place of Presentation
      Osaka International Convention Center, Osaka, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Zinc has a role in dendritic cell maturation.2006

    • Author(s)
      Morikawa, H.
    • Organizer
      The 36^<th> Annual Meting of the Japanese Society for Immunology
    • Place of Presentation
      Osaka International Convention Center, Osaka, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] A mutant mouse having excess amount of memory T cells is a model mouse of Omenn syndrome.2006

    • Author(s)
      Khiong, K.
    • Organizer
      The 36^<th> Annual Meting of the Japanese Society for Immunology
    • Place of Presentation
      Osaka International Convention Center, Osaka, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] IL-2 functions increased by an anti-IL-2 mAb in vivo.2006

    • Author(s)
      Sawa, Y.
    • Organizer
      The 36^<th> Annual Meting of the Japanese Society for Immunology
    • Place of Presentation
      Osaka International Convention Center, Osaka, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] IL-6/IL-6 family-STAT3-IL-7 cascade causes an autoimmune arthritis via CD4+T-cell homeostatic proliferation in gp130^<F759/F759> mice2006

    • Author(s)
      Ogura, H.
    • Organizer
      The 36^<th> Annual Meting of the Japanese Society for Immunology
    • Place of Presentation
      Osaka International Convention Center, Osaka, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Involvement of STAT3 signaling for IL-6-mediated development of IL-17 producing CD4 T cells.2006

    • Author(s)
      Nishihara, M.
    • Organizer
      The 36^<th> Annual Meting of the Japanese Society for Immunology
    • Place of Presentation
      Osaka International Convention Center, Osaka, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] CD8 T cell homeostatic proliferation in vivo is regulated by IL-4 from NKT cells.2006

    • Author(s)
      Ueda, N.
    • Organizer
      The 36^<th> Annual Meting of the Japanese Society for Immunology
    • Place of Presentation
      Osaka International Convention Center, Osaka, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] サイトカインとリウマチ2005

    • Author(s)
      平野俊夫
    • Organizer
      第16回日本リウマチ学会関東支部学術集会 シンポジウム2
    • Place of Presentation
      つくば国際会議場第1会場
    • Year and Date
      2005-12-10
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Cytokines and rheumatism2005

    • Author(s)
      Hirano, T.
    • Organizer
      The 16^<th> Science Meeting of Kanto branch of Japan College of Rheumatology. Symposium 2 “From Immunobiology to Rheumatology"
    • Place of Presentation
      Tsukuba International Congress Center, Japan.
    • Year and Date
      2005-12-10
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] IL-2ファミリーサイトカインによるメモリーCD8+T細胞の維持機構の解析2005

    • Author(s)
      村上正晃
    • Organizer
      第14回目本癌病態治療研究会
    • Place of Presentation
      札幌プリンスホテル
    • Year and Date
      2005-06-24
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Analysis of mechanism for maintenance of memory CD8+T cells by IL-2 family cytokine.2005

    • Author(s)
      Murakami, M.
    • Organizer
      The 14^<th> Annual Meeting of Japanese Society of Strategies for Cancer Research and Therapy
    • Place of Presentation
      Sapporo Prince Hotel, Japan.
    • Year and Date
      2005-06-24
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Zinc transporter Liv1, a target of Stat3, controls epithelial-mesenchymal transition through regulating nuclear localization of snail2005

    • Author(s)
      平野俊夫
    • Organizer
      The 58th Annual Meeting of Japan Society for Cell Biology (JSCB58)
    • Place of Presentation
      Omiya Sonic City, Saitama
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Interaction of activated IL-6 producing CD4^+ T cell with non-hematopoietic tissues having gpl30 mutation causes a rheumatoid arthritis-like disease2005

    • Author(s)
      平野俊夫
    • Organizer
      RCAI-JSI International Symposium on Immunology 2005
    • Place of Presentation
      Pacifico Yokohama
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Hyperactivation of gpl30-Mediated STAT3 Signaling Induces a Rheumatoed Arthritis Like Disease That is Dependent on MHC class II Restricted CD4^+T Cells2005

    • Author(s)
      村上正晃
    • Organizer
      Uehara Memorial Foundation Symposium-The Innate Immune System
    • Place of Presentation
      Keio Plaza Inter-Continental Hotel, Tokyo
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Interaction of activated IL-6 producing CD4十T cells with non-hematopoietic tissues having a gpl30 mutation causes a rheumatoid arthritis-like disease.2005

    • Author(s)
      平野俊夫
    • Organizer
      Mini-Symposium on Cytokine Research, Institute of Biomedical Sciences Academia Sinica
    • Place of Presentation
      Taipei
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Identification of responsible gene(s)in a spontaneous mutant of C57BL/10, which carries excess amount of memory T cells.2005

    • Author(s)
      キー・キョン
    • Organizer
      第35回日本免疫学会総会・学術集会
    • Place of Presentation
      パシフイコ横浜
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] gpl30F759マウスの関節炎の病因へのT細胞homeostatic proliferationの関与2005

    • Author(s)
      澤新一郎
    • Organizer
      第35回日本免疫学会総会・学術集会
    • Place of Presentation
      パシフイコ横浜
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] T細胞免疫寛容導入時におけるIL-6の役割2005

    • Author(s)
      中川貴之
    • Organizer
      第35回日本免疫学会総会・学術集会
    • Place of Presentation
      パシフイコ横浜
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 樹状細胞活性化時におけるTRIF-GEF-H1-RhoBパスウェイを介したMHC Class2(CII)小胞の輸送調節機構2005

    • Author(s)
      加門北斗
    • Organizer
      第35回日本免疫学会総会・学術集会
    • Place of Presentation
      パシフイコ横浜
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] IL-6信号の活性化T細胞の生存に与える影響2005

    • Author(s)
      熱海徹
    • Organizer
      第35回日本免疫学会総会・学術集会
    • Place of Presentation
      パシフイコ横浜
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Zinc transporter Liv1, a target of Stat3, controls epithelial-mesenchymal transition through regulating nuclear localization of snail.2005

    • Author(s)
      Hirano, T.
    • Organizer
      The 58th Annual Meeting of Japan Society for Cell Biology (JSCB58)
    • Place of Presentation
      Omiya Sonic City, Saitama, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Interaction of activated IL-6 producing CD4^+ T cell with non-hematopoietic tissues having gp130 mutation causes a rheumatoid arthritis-like disease.2005

    • Author(s)
      Hirano, T.
    • Organizer
      RCAI-JSI International Symposium on Immunology 2005, "Mechanisms of Immune Responses in Health and Diseases"
    • Place of Presentation
      Pacifico Yokohama, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Hyperactivation of gp130-Mediated STAT3 Signaling Induces a Rheumatoed Arthritis Like Disease That is Dependent on MHC class II Restricted CD4^+T Cells2005

    • Author(s)
      Murakami, M.
    • Organizer
      Uehara Memorial Foundation Symposium-The Innate Immune System : Strategies for Disease Control
    • Place of Presentation
      Keio Plaza Inter-Continental Hotel, Tokyo, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Interaction of activated IL-6 producing CD4+T cells with non-hematopoietic tissues having a gp130 mutation causes a rheumatoid arthritis-like disease.2005

    • Author(s)
      Hirano, T.
    • Organizer
      Mini-Symposium on Cytokine Research, Institute of Biomedical Sciences Academia Sinica
    • Place of Presentation
      Taipei.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Identification of responsible gene(s) in a spontaneous mutant of C57BL/10, which carries excess amount of memory T cells.2005

    • Author(s)
      Khiong, K.
    • Organizer
      The 35^<th> Annual Meting of the Japanese Society for Immunology
    • Place of Presentation
      Pacifico Yokohama, Yokohama, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] gp130^<F759/F759> mice develop rheumatoid arthritis-like disease through aberrant homeostatic proliferation of CD4+T cells.2005

    • Author(s)
      Sawa, S.
    • Organizer
      The 35^<th> Annual Meting of the Japanese Society for Immunology
    • Place of Presentation
      Pacifico Yokohama, Yokohama, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] A role of IL-6 in the induction of T cell self-immune torelance.2005

    • Author(s)
      Nakagawa, T.
    • Organizer
      The 35^<th> Annual Meting of the Japanese Society for Immunology
    • Place of Presentation
      Pacifico Yokohama, Yokohama, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] TRIF-GEFH1-RhoB cascade regulates surface expression of MHC class II in dendritic cells that is critical for CD4+T cell activation.2005

    • Author(s)
      Kamon, H.
    • Organizer
      The 35^<th> Annual Meting of the Japanese Society for Immunology
    • Place of Presentation
      Pacifico Yokohama, Yokohama, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Effect of IL-6 signaling in survival of activated T cells.2005

    • Author(s)
      Atsumi, T.
    • Organizer
      The 35^<th> Annual Meting of the Japanese Society for Immunology
    • Place of Presentation
      Pacifico Yokohama, Yokohama, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] サイトカインシグナル異常による関節リウマチマウスモデル2004

    • Author(s)
      石原克彦
    • Organizer
      第6回なにわ骨代謝・骨腫瘍研究会 特別講演
    • Place of Presentation
      ホテルニューオータニ大阪
    • Year and Date
      2004-10-30
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] A mouse model of rheumatoid arthritis developed by aberrant cytokine signaling.2004

    • Author(s)
      Ishihara, K.
    • Organizer
      The 6^<th> Naniwa Society for Bone metabolism and tumor. Special lecture
    • Place of Presentation
      Hotel New Otani Osaka, Japan.
    • Year and Date
      2004-10-30
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Zn transporter LIV1, a new player of epithelial-mesenchymal transition2004

    • Author(s)
      平野俊夫
    • Organizer
      RCAI CDB Joint Form
    • Place of Presentation
      1st floor of Building C, CDB
    • Year and Date
      2004-10-26
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Zn transpoter LIV1, a new player in epithelial mesenchymal transition in zebrafish gastrulation.2004

    • Author(s)
      Hirano, T.
    • Organizer
      RCAI CDB Joint Form
    • Place of Presentation
      1st floor of Building C, CDB, Japan.
    • Year and Date
      2004-10-26
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Zn transporter LIV1, a new player of epithelial-mesenchymal transition2004

    • Author(s)
      平野俊夫
    • Organizer
      シンポジウム「The Forefront of B Cell Research」
    • Place of Presentation
      東京大学医科学研究所
    • Year and Date
      2004-10-19
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Aberrant signal of gpl30 and autoimmune arthritis2004

    • Author(s)
      石原克彦
    • Organizer
      シンポジウム「The Forefront of B Cell Research」
    • Place of Presentation
      東京大学医科学研究所
    • Year and Date
      2004-10-19
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Zn transporter LIV1, a new player of epithelial-mesenchymal transition2004

    • Author(s)
      Hirano, T.
    • Organizer
      Symposium 「The Forefront of B Cell Research」
    • Place of Presentation
      The Institute of Medical Science, The University of Tokyo, Japan.
    • Year and Date
      2004-10-19
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Aberrant signal of gp130 and autoimmune arthritis2004

    • Author(s)
      Ishihara, K.
    • Organizer
      Symposium 「The Forefront of B Cell Research」
    • Place of Presentation
      The Institute of Medical Science, The University of Tokyo, Japan.
    • Year and Date
      2004-10-19
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 原腸陥入におけるEpithelial-Mesenchymal Transitionの分子機構 : STAT3/LIV1亜鉛輸送蛋白/Snailの役割2004

    • Author(s)
      平野俊夫
    • Organizer
      OBIセミナー
    • Place of Presentation
      大阪バイオサイエンス研究所
    • Year and Date
      2004-09-24
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Molecular mechanism of Epithelial-Mesenchymal Transition in gastrulation : Roles of STAT3/ Zn transporter LIV1/Snail.2004

    • Author(s)
      Hirano, T.
    • Organizer
      OBI Seminar
    • Place of Presentation
      Osaka Bioscience Institute, Japan.
    • Year and Date
      2004-09-24
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 免疫における自己、非自己認識 : その可塑性2004

    • Author(s)
      平野俊夫
    • Organizer
      第44回生化学若手の会夏の学校ワークショップ
    • Place of Presentation
      国立オリンピック記念青少年総合センター
    • Year and Date
      2004-08-20
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Self/non-self recognition by the immune system : Its invertibility.2004

    • Author(s)
      Hirano, T.
    • Organizer
      The 44^<th> Summer school workshop for young biochemist
    • Place of Presentation
      National Olympics Memorial Youth Center, Japan.
    • Year and Date
      2004-08-20
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] IL-2ファミリーサイトカインによるメモリーCD8+T細胞の維持機構の解析2004

    • Author(s)
      村上 正晃
    • Organizer
      第13回日本アポトーシス研究会学術集会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2004-07-13
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Analysis of mechanism for maintenance of memory CD8+T cells by IL-2 family cytokine.2004

    • Author(s)
      Miurakami, M.
    • Organizer
      Japanese Society for Apotosis, The 13^<th> Science Meeting of Japanese Society for Apoptosis
    • Place of Presentation
      Nagoya International Convention Center, Nagoya, Japan.
    • Year and Date
      2004-07-13
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 原腸陥入におけるEpithelial-Mesenchymal Transitionの分子機構 : 細胞の可動性を制御する乳がん関連分子、LIV1亜鉛輸送蛋白の役割2004

    • Author(s)
      平野俊夫
    • Organizer
      国立癌センター講演
    • Place of Presentation
      国立癌センター
    • Year and Date
      2004-06-18
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Molecular mechanism of Epithelial-Mesenchymal-Transition in gastrulation : roles of Zn transporter LIV1, a breast cancer-related molecule regulating cell motility.2004

    • Author(s)
      Hirano, T.
    • Organizer
      “Roles of Zn transporter LIV1" National Cancer Center Seminar
    • Place of Presentation
      National Cancer Center Seminar, Japan.
    • Year and Date
      2004-06-18
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] サイトカインの分子生物学的研究2004

    • Author(s)
      平野俊夫
    • Organizer
      藤原賞受賞記念講演
    • Place of Presentation
      学士院会館
    • Year and Date
      2004-06-17
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Research on Molecular Mechanisms of Cytokine.2004

    • Author(s)
      Hirano, T.
    • Organizer
      The Fujihara Award Winning commemoration lecture
    • Place of Presentation
      Gakushikaikan, Tokyo, Japan.
    • Year and Date
      2004-06-17
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] インターロイキン6研究 : 免疫、発生、癌研究の橋渡し2004

    • Author(s)
      平野俊夫
    • Organizer
      第1 3回東京免疫フォーラム 特別講演
    • Place of Presentation
      東大医科研・講堂
    • Year and Date
      2004-05-18
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Interleukin-6 research : Bridge of the researches of immunity, embryo, and cancer.2004

    • Author(s)
      Hirano, T.
    • Organizer
      The 13^<th> Tokyo immune forum. Special lecture
    • Place of Presentation
      The Institute of Medical Science, The University of Tokyo, Japan.
    • Year and Date
      2004-05-18
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 原腸陥入におけるEpithelial-Mesenchymal Transitionの分子機構 : STAT3からSnailへの新たなシグナルの担い手LIV12004

    • Author(s)
      山下晋
    • Organizer
      大阪大学生命研究交流会
    • Place of Presentation
      大阪大学大学院生命機能研究科 セミナー室
    • Year and Date
      2004-05-12
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Molecular mechanism of Epithelial-Mesenchymal-Transition in gastrulation : LIV1, a new signal messenger from STAT3 to Snail.2004

    • Author(s)
      Yamashita, S.
    • Organizer
      Frontier Bioscience Colloquium
    • Place of Presentation
      Graduate School of Frontier Biosciences, Osaka University, Japan.
    • Year and Date
      2004-05-12
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Jaks and Stats in Epithelia-Mesenchymal Transition of Zebrafish Gastrula Organizer.2004

    • Author(s)
      山下 晋
    • Organizer
      Keystone Symposia.
    • Place of Presentation
      Fairmont Chateau Whistler, Whistler, British Columbia, Canada
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Day3 neonatal thymectomy accelerates arthritis onset in gpl30F759 mice CD25-CD4+T cell dependent manner.2004

    • Author(s)
      澤 新一郎
    • Organizer
      12^<tn> International Congress of Immunology and4^<th> Annual Conference of FOCIS
    • Place of Presentation
      Montreal, Canada
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 比一2 depletion induces IL-7- or IL-15-independent division of memory CD8十T cells in vivo : A possible involvement of a novel IL-2Rb-using cytokine.2004

    • Author(s)
      上村 大輔
    • Organizer
      12^<tn> International Congress of Immunology and 4^<th> Annual Conference of FOCIS
    • Place of Presentation
      Montreal, Canada
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] pl30 signaling modified SEB-induced activated T cell deletion in vivo.2004

    • Author(s)
      熱海 徹
    • Organizer
      12^<tn> International Congress of Immunology and 4^<tn> Annual Conference of FOCIS
    • Place of Presentation
      Montreal, Canada
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Development of autoimmune rheumatoid arthritis like disease by abnormal signaling of IL=6 family cytokine.2004

    • Author(s)
      平野俊夫
    • Organizer
      東北大学21世紀COEプログラム第1[回国際シンポジウム“Lymphocyte Development and Immunological Disorders"
    • Place of Presentation
      東北大学大学院医学系研究科
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] gpl30^<F759/F759>マウスにおけるCD4+T細胞の恒常的維持の異常とリュウマチ様関節炎発症2004

    • Author(s)
      澤新一郎
    • Organizer
      第34回日本免疫学会総会・学術集会
    • Place of Presentation
      ホテルロイトン札幌
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] メモリーCD8+T細胞の維持に関与する新規TL-2/15Rbサイトカインの存在2004

    • Author(s)
      上村大輔
    • Organizer
      第34回日本免疫学会総会・学術集会
    • Place of Presentation
      ホテルロイトン札幌
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] IL-6による樹状細胞を介したT細胞の活性の変化2004

    • Author(s)
      中川貴之
    • Organizer
      第34回日本免疫学会総会・学術集会
    • Place of Presentation
      ホテルロイトン札幌 他
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 樹状細胞におけるアクチンフィラメント、微小管等の細胞骨格依存的なMHC Class2小胞の局在維持、輸送調節機構2004

    • Author(s)
      加門北斗
    • Organizer
      第34回, 日本免疫学会総会・学術集会
    • Place of Presentation
      ホテルロイトン札幌 他
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] IL-6信号の活性化T細胞の生存に与える影響2004

    • Author(s)
      熱海徹
    • Organizer
      第34回日本免疫学会総会・学術集会
    • Place of Presentation
      ホテルロイトン札幌 他
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] FceRI架橋刺激による顆粒の細胞膜移行にはカルシュウム非依存的な微小管形成が必要である2004

    • Author(s)
      西田圭吾
    • Organizer
      第34回日本免疫学会総会・学術集会
    • Place of Presentation
      ホテルロイトン札幌 他
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 樹状細胞の成熟過程における微小管形成とMHCII発現に及ぼすTL-6の効果2004

    • Author(s)
      北村秀光
    • Organizer
      第34回日本免疫学会総会・学術集会
    • Place of Presentation
      ホテルロイトン札幌 他
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Jaks and Stats in Epithelial-Mesenchymal Transition of Zebrafish Gastrula Organizer.2004

    • Author(s)
      Yamashita, S.
    • Organizer
      Keystone Symposia. Fairmont Chateau Whistler
    • Place of Presentation
      Whistler, British Columbia, Canada.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] IL-2 depletion induces IL-7- or IL-15-independent division of memory CD8+ T cells in vivo : A possible involvement of a novel IL-2Rb-using cytokine.2004

    • Author(s)
      Kamimura, D.
    • Organizer
      12^<th> International Congress of Immunology and 4^<th> Annual Conference of FOCIS
    • Place of Presentation
      Montreal, Canada.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Day3 neonatal thymectomy accelerates arthritis onset in gp130F759 mice CD25-CD4+ T cell dependent manner.2004

    • Author(s)
      Sawa, S.
    • Organizer
      12^<th> International Congress of Immunology and 4^<th> Annual Conference of FOCIS
    • Place of Presentation
      Montreal, Canada.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] p130 signaling modified SEB-induced activated T cell deletion in vivo.2004

    • Author(s)
      Atsumi, T.
    • Organizer
      12^<th> International Congress of Immunology and 4^<th> Annual Conference of FOCIS
    • Place of Presentation
      Montreal, Canada.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Development of autoimmune rheumatoid arthritis-like disease by abnormal signaling of IL=6 family cytokine.2004

    • Author(s)
      Hirano, T.
    • Organizer
      Tohoku University 21^<st> century COE Program, The 1st International Symposium
    • Place of Presentation
      Graduate School of Medicine, Tohoku University, Japan
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] IL-6-Mediated Controlling of Dendritic Cell Maturation and T Cell Responses.2004

    • Author(s)
      Murakami, M.
    • Organizer
      The 34^<th> Annual Meting of the Japanese Society for Immunology, Symposium
    • Place of Presentation
      Hotel Roitone Sapporo, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] gp130^<F759/F759> mice develop rheumatoid arthritis-like disease through aberrant homeostatic proliferation of CD4+T cells.2004

    • Author(s)
      Sawa, S.
    • Organizer
      The 34^<th> Annual Meting of the Japanese Society for Immunology
    • Place of Presentation
      Hotel Roitone Sapporo, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] New IL-2/15Rb cytokines involved in maintenance of memory CD8+T cells.2004

    • Author(s)
      Kamimura, D.
    • Organizer
      The 34^<th> Annual Meting of the Japanese Society for Immunology
    • Place of Presentation
      Hotel Roitone Sapporo, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] The change of T cell activation through IL-6-mediated dendritic cells.2004

    • Author(s)
      Nakagawa, T.
    • Organizer
      The 34^<th> Annual Meting of the Japanese Society for Immunology
    • Place of Presentation
      Hotel Roitone Sapporo, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Mechanism of cytoskeleton-dependent localization maintenance and transport regulation of MHC class II vesicles in dendritic cells.2004

    • Author(s)
      Kamon, H.
    • Organizer
      The 34^<th> Annual Meting of the Japanese Society for Immunology
    • Place of Presentation
      Hotel Roitone Sapporo, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] IL-6 reduces intracellular MHC class II αβ-dimer level through Cathepsin S activity in dendritic cells.2004

    • Author(s)
      Kitamura, H.
    • Organizer
      The 34^<th> Annual Meting of the Japanese Society for Immunology
    • Place of Presentation
      Hotel Roitone Sapporo, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Effect of IL-6 signaling in survival of activated T cells.2004

    • Author(s)
      Atsumi, T.
    • Organizer
      The 34^<th> Annual Meting of the Japanese Society for Immunology
    • Place of Presentation
      Hotel Roitone Sapporo, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] FceRI-mediated mast cell degranulation requires calcium-independent microtubule-dependent translocation of granules to the plasma membrane.2004

    • Author(s)
      Nishida, K.
    • Organizer
      The 34^<th> Annual Meting of the Japanese Society for Immunology
    • Place of Presentation
      Hotel Roitone Sapporo, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] インターロイキン6シグナル異常と自己免疫疾患、特に関節リウマチについて2003

    • Author(s)
      平野俊夫
    • Organizer
      千里ライフサイエンスシンポジウム
    • Place of Presentation
      千里ライフサイエンスセンター
    • Year and Date
      2003-09-02
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Aberrant IL-6 signaling and autoimmune disease : especially about rheumatoid arthritis.2003

    • Author(s)
      Hirano, T.
    • Organizer
      Senri Life Science Symposium "The frontier of immune regulation and autoimmune disease research"
    • Place of Presentation
      Senri Life Science Center, Japan.
    • Year and Date
      2003-09-02
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] サイトカイン受容体gpl30のシグナル異常により発症する関節リウマチマウスモデル2003

    • Author(s)
      石原克彦
    • Organizer
      第9回自己免疫研究会
    • Place of Presentation
      東海大学校学友館
    • Year and Date
      2003-07-12
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] A mouse model of rheumatoid arthritis developed by aberrant signal of cytokine receptor gp130.2003

    • Author(s)
      Ishihara, K.
    • Organizer
      The 9^<th> Autoimmunity Workshop
    • Place of Presentation
      Tokai University Alumni Hall, Japan.
    • Year and Date
      2003-07-12
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Gpl30シグナル異常と慢性関節リウマチ様自己免疫疾患2003

    • Author(s)
      平野俊夫
    • Organizer
      第26回日本医学会総会
    • Place of Presentation
      福岡国際会議場
    • Year and Date
      2003-04-04
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Aberrant signal of gp130 and rheumatoid arthritis-like disease2003

    • Author(s)
      Hirano, T.
    • Organizer
      The 26^<th> General Assembly of The Japan Medical Congress
    • Place of Presentation
      Fukuoka International Convention Center, Fukuoka, Japan.
    • Year and Date
      2003-04-04
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] p130F759変異を有するマウス微小環境は活性化T細胞の生存を促進する2003

    • Author(s)
      熱海 徹
    • Organizer
      第33回日本免疫学会総会・学術集会
    • Place of Presentation
      福岡国際会議場マリンメッセ福岡
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] サイトカイン受容体gpl30の点変異に由来する自己免疫性関節炎マウスの滑膜組織における免疫担当細胞の局在2003

    • Author(s)
      石原克彦
    • Organizer
      第33回日本免疫学会総会・学術集会
    • Place of Presentation
      福岡国際会議場マリンメッセ福岡
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] G-CSFは末梢のT細胞ホメオスタシスに関与する重要なサイトカインである2003

    • Author(s)
      上村 大輔
    • Organizer
      第33回日本免疫学会総会・学術集会
    • Place of Presentation
      福岡国際会議場マリンメッセ福岡
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 樹状細胞成熟時のIL-6によるMHC Class2分子輸送阻害2003

    • Author(s)
      加門 北斗
    • Organizer
      第33回日本免疫学会総会・学術集会
    • Place of Presentation
      福岡国際会議場マリンメッセ福岡
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] gpl30信号はT細胞の増殖、生存を制御する2003

    • Author(s)
      澤 新一郎
    • Organizer
      第33回日本免疫学会総会・字術集会
    • Place of Presentation
      福岡国際会議場マリンメッセ福岡
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] gpl30信号と臓器特異的自己免疫疾患の関係2003

    • Author(s)
      中川 貴之
    • Organizer
      第33回日本免疫学会総会・学術集会
    • Place of Presentation
      福岡国際会議場マリンメッセ福岡
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 抗IL-2抗体投与によるメモリー表現型CD8^+T細胞分裂はCD4+T細胞依存的・IL-15非依存的機構によって誘導される2003

    • Author(s)
      村上 正晃
    • Organizer
      第33回日本免疫学会総会・学術集会
    • Place of Presentation
      福岡国際会議場マリンメッセ福岡
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] IL-6は樹状細胞のリソソームプロテアーゼを介してMHCクフスII分子量を減少させる2003

    • Author(s)
      北村秀光
    • Organizer
      第33回日本免疫学会総会・学術集会
    • Place of Presentation
      福岡国際会議場・マリンメッセ福岡
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] FceRIシグナル伝達におけるアダプター分子Gab2の役割2003

    • Author(s)
      西田圭吾
    • Organizer
      第33回日本免疫学会総会・学術集会
    • Place of Presentation
      福岡国際会議場・マリンメッセ福岡
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] IL-6は樹状細胞の成熟過程を阻害する2003

    • Author(s)
      朴星珠
    • Organizer
      第33回日本免疫学会総会・学術集会
    • Place of Presentation
      福岡国際会議場・マリンメッセ福岡
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] IL-6-Mediated Controlling of Dendritic Cell Maturation and T Cell Responses.2003

    • Author(s)
      村上正晃
    • Organizer
      第34回日本免疫学会総会・学術集会シンポジウム
    • Place of Presentation
      ホテルロイトン札幌 他
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Increase in activated T cells in the micro enviroments of gp130^<F759/F759> Mice.2003

    • Author(s)
      Atsumi, T.
    • Organizer
      The 33^<th> Annual Meting of the Japanese Society for Immunology
    • Place of Presentation
      Fukuoka International Convention Center, Fukuoka, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Localization of immune cells in the synovial tissues of autoimmune rheumatoid arthritis-gp130^<F759/F759> mice.2003

    • Author(s)
      Ishihara, K.
    • Organizer
      The 33^<th> Annual Meting of the Japanese Society for Immunology
    • Place of Presentation
      Fukuoka International Convention Center, Fukuoka, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] G-CSF is a critical cytokine involved in the homeostasis of peripheral T cells.2003

    • Author(s)
      Kamimura, D.
    • Organizer
      The 33^<th> Annual Meting of the Japanese Society for Immunology
    • Place of Presentation
      Fukuoka International Convention Center, Fukuoka, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Inhibition of MHC class II transport by IL-6 during dendritic cell matulation.2003

    • Author(s)
      Kamon, H.
    • Organizer
      The 33^<th> Annual Meting of the Japanese Society for Immunology
    • Place of Presentation
      Fukuoka International Convention Center, Fukuoka, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] gp130 signaling regulates the proliferation and survival of T cells.2003

    • Author(s)
      Sawa, S.
    • Organizer
      The 33^<th> Annual Meting of the Japanese Society for Immunology
    • Place of Presentation
      Fukuoka International Convention Center, Fukuoka, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Relationship between gp130 signaling and organ specific autoimmune disease.2003

    • Author(s)
      Nakagawa, T.
    • Organizer
      The 33^<th> Annual Meting of the Japanese Society for Immunology
    • Place of Presentation
      Fukuoka International Convention Center, Fukuoka, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] IL-2 depletion induces CD4+T cell-dependent or IL-15-independent division of memory CD8+T cells.2003

    • Author(s)
      Murakami, M.
    • Organizer
      The 33^<th> Annual Meting of the Japanese Society for Immunology
    • Place of Presentation
      Fukuoka International Convention Center, Fukuoka, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] IL-6 reduces intracellular MHC class II αβ-dimer level through Cathepsin S activity in dendritic cells.2003

    • Author(s)
      Kitamura, H.
    • Organizer
      The 33^<th> Annual Meting of the Japanese Society for Immunology
    • Place of Presentation
      Fukuoka International Convention Center, Fukuoka, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] A critical role of Gab2 in FceRI signaling.2003

    • Author(s)
      Nishida, K.
    • Organizer
      The 33^<th> Annual Meting of the Japanese Society for Immunology
    • Place of Presentation
      Fukuoka International Convention Center, Fukuoka, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] IL-6 inhibits the maturation process of dendritic cells.2003

    • Author(s)
      Park, Song-J.
    • Organizer
      The 33^<th> Annual Meting of the Japanese Society for Immunology
    • Place of Presentation
      Fukuoka International Convention Center, Fukuoka, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Book] Grasp a pTyr-peptide by its SOCS.2006

    • Author(s)
      Hirano, T., M.Murakami.
    • Total Pages
      4
    • Publisher
      Dev. Cell
    • Related Report
      2006 Annual Research Report
  • [Book] Interleukin -6 in Encyclopedia of Endocrinology and Endocrine diseas2004

    • Author(s)
      Ohtani, T., T. Hirano.
    • Total Pages
      7
    • Publisher
      Academic Press
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Book] Interleukin -6 in Encyclopedia of Endocrinology and Endocrine Diseases2004

    • Author(s)
      Ohtani, T., T.Hirano.
    • Total Pages
      7
    • Publisher
      Academic Press
    • Related Report
      2004 Annual Research Report
  • [Book] T.New IL-6 (gp130) family cytokine members, CLC/NNT1/BSF3 and IL-27. Growth Facotrs2004

    • Author(s)
      Murakami, M., D.Kamimura, T.Hirano
    • Total Pages
      3
    • Related Report
      2004 Annual Research Report
  • [Book] signal Transducers and Activators of Transcription (STATs) : Activatio and Biology2003

    • Author(s)
      Yamashita, S., Hirano, T.
    • Total Pages
      13
    • Publisher
      Kluwer Academic Publishers
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Book] Encyclopedia of Hormones2003

    • Author(s)
      Kamimura, D., Hirano, T.
    • Total Pages
      10
    • Publisher
      Academic Press
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Book] Signal Transducers and Activators of Transcription (STATs) : Activatio and Biology2003

    • Author(s)
      Kamimura, D., Hirano, T.
    • Total Pages
      21
    • Publisher
      Kluwer Academic Publishers
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Book] Reviews of Physiology, Biochemistry and Pharmacology2003

    • Author(s)
      Kamimura, D., Ishihara, K., Hirano, T.
    • Total Pages
      38
    • Publisher
      Springer-Verlag
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Remarks] 「研究成果報告書概要(和文)」より

    • URL

      http://www.med.osaka-u.ac.jp/pub/molonc/www/index.html

    • Related Report
      2007 Final Research Report Summary
  • [Remarks]

    • URL

      http://www.med.osaka-u.ac.jp/pub/molonc/www/index.html

    • Related Report
      2007 Annual Research Report
  • [Patent(Industrial Property Rights)] 肥満細胞脱顆粒制御剤2006

    • Inventor(s)
      平野俊夫, 西田圭吾
    • Industrial Property Rights Holder
      平野俊夫, 西田圭吾
    • Filing Date
      2006-06-08
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Patent(Industrial Property Rights)] 亜鉛イオンによる転写因子STATの活性制御(亜鉛によるSTAT転写因子の活性制御)2006

    • Inventor(s)
      平野俊夫, 村上正晃, 深田俊幸(理研、ゼリア新薬工業)
    • Industrial Property Rights Holder
      平野俊夫, 村上正晃, 深田俊幸(理研、ゼリア新薬工業)
    • Filing Date
      2006-11-28
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Patent(Industrial Property Rights)] 未成熟樹状細胞の成熟化調節剤2005

    • Inventor(s)
      平野俊夫, 村上正晃
    • Industrial Property Rights Holder
      平野俊夫, 村上正晃
    • Patent Publication Number
      2005-015413
    • Acquisition Date
      2005-06-28
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Publications] Ishihara, K., et al.: "The point mutation of Y759 of the IL-6 family receptor gp130 synergizes with HTLV-1 pX in promoting RA-like arthritis."Int.Immunol.. 16. 455-465 (2004)

    • Related Report
      2003 Annual Research Report
  • [Publications] Yasukawa, H., et al.: "IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages."Nature Immunology. 4. 551-556 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] Yamashita, S., Hirano, T.: "Signal Transducers and Activators of Transcription (STATs) : Activation and Biology"Kluwer Academic Publrshers. 13 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] Kamimura, D., Hirano, T.: "Signal Transducers and Activators of Transcription (STATs) : Activation and Biology"Kluwer Academic Publrshers. 21 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] Kamimura, D., Ishihara, K., Hirano, T.: "Reviews of Physiology, Biochemistry and Pharmacology"Springer-Verlag. 38 (2003)

    • Related Report
      2003 Annual Research Report

URL: 

Published: 2003-04-01   Modified: 2018-03-28  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi