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Evaluation of Signal and Noise and Exposure in Medical Image for CAD

Research Project

Project/Area Number 15070205
Research Category

Grant-in-Aid for Scientific Research on Priority Areas

Allocation TypeSingle-year Grants
Review Section Science and Engineering
Research InstitutionNagoya University

Principal Investigator

IKEDA Mitsuru  Nagoya University, Faculty of Medicine, Associate Professor (50184437)

Co-Investigator(Kenkyū-buntansha) ITOH Shigeki  Nagoya University, Faculty of Medicine, Professor (20184658)
IMAI Kuniharu  Nagoya University, Faculty of Medicine, Assistant Professor (20335053)
WADA Shinichi  Niigata University, Faculty of Medicine, Professor (80105519)
NISHIZAWA Kanae  Nagoya University, National Institute of Radiological Sciences, Section Head (40086575)
FURUKAWA Akira  Nagoya University, National Institute of Radiological Sciences, Senior Staff Scientist (70238666)
石垣 武男  名古屋大学, 大学院・医学系研究科, 教授 (60094356)
Project Period (FY) 2003 – 2006
Project Status Completed (Fiscal Year 2007)
Budget Amount *help
¥64,000,000 (Direct Cost: ¥64,000,000)
Fiscal Year 2006: ¥16,000,000 (Direct Cost: ¥16,000,000)
Fiscal Year 2005: ¥16,000,000 (Direct Cost: ¥16,000,000)
Fiscal Year 2004: ¥16,000,000 (Direct Cost: ¥16,000,000)
Fiscal Year 2003: ¥16,000,000 (Direct Cost: ¥16,000,000)
KeywordsImage Quality Evaluation / Signal Detection Theory / Medical Exposure / 画像認知
Research Abstract

We have confirmed that the spatial resolution difference of CT images among CT scanners certainly influenced the diagnostic performance of CAD. To obtain the robustness of CAD for the dependency on CT scanners and improve the performance of CAD, we have developed the method to transform the acquired CT images to the standard ones by using the 3-D LSF which was measured for the considering CT scanner ; and, we have shown that the diagnostic performance of some CADs was improved by this method.
Further, we have assessed the method of estimating image noise SD on CT images, and have shown that the method for estimating the noise variance of an image proposed by Rank et al. will be able to estimate the CT image noise SD with reasonable accuracy, unless the neighborhood pixels does not too much correlate with each other. We have also shown that streak artifacts on CT images can be statistically modeled by the Gumbel distribution, and, by using this result, we have devised the new evaluation method of streak artifacts on CT images that we call as the Gumbel evaluation method. Further more, we have assessed whether or not the fractal-feature distance could be a substitute for the observer performance index in Contrast-Detail (C-D) examination and image-reading study for evaluation of anatomic noise ; and, we have shown that all C-D and chest images can be analyzed by the virtual volume method and that the fractal-feature distances would be equivalent to IQFs and observer's confidence levels.
In addition, we have measured the dose distributions of various organs and tissues during examinations with multi-detector row CT, under the irradiation conditions close to actual clinical examinations, and derived the corresponding effective doses. Further, we have evaluated the relationship between radiation dose and various image quality indices.

Report

(5 results)
  • 2007 Final Research Report Summary
  • 2006 Annual Research Report
  • 2005 Annual Research Report
  • 2004 Annual Research Report
  • 2003 Annual Research Report
  • Research Products

    (47 results)

All 2007 2006 2005 2004 Other

All Journal Article (37 results) (of which Peer Reviewed: 3 results) Presentation (1 results) Book (3 results) Publications (6 results)

  • [Journal Article] Fractal-feature distance analysis of radiographic image2007

    • Author(s)
      Kuniharu Imai, et al.
    • Journal Title

      Academic Radiology 14-2

      Pages: 137-143

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Fractal-feature distance analysis of radiographic image2007

    • Author(s)
      Kuniharu Imai, et al
    • Journal Title

      Academic Radiology 14-2

      Pages: 137-143

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Information loss in visual assessments of medical images2007

    • Author(s)
      Takanaga Niimi et al.
    • Journal Title

      European Journal of Radiology 61・2

      Pages: 362-366

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Fractal-feature distance analysis of radiographic image2007

    • Author(s)
      Kuniharu Imai et al.
    • Journal Title

      Academic Radiology 14・2

      Pages: 152-158

    • Related Report
      2006 Annual Research Report
  • [Journal Article] フラクタル特徴距離を用いた解剖学的ノイズの評価2007

    • Author(s)
      今井國治, 他
    • Journal Title

      電子情報通信学会技術報告 106・509

      Pages: 173-176

    • NAID

      110006201359

    • Related Report
      2006 Annual Research Report
  • [Journal Article] The CT image standardization based on the verified PSF2007

    • Author(s)
      Shinichi Wada et al.
    • Journal Title

      SPIE Medical Imaging proceedings (In Press)

    • Related Report
      2006 Annual Research Report
  • [Journal Article] An effective method to verify line and point spread functions measured in computed tomography2006

    • Author(s)
      Masaki Ohkubo, et al.
    • Journal Title

      Medical Physics 33-8

      Pages: 2757-2764

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] An effective method to verify line and point spread functions measured in computed tomography2006

    • Author(s)
      Masaki Ohkubo, et al
    • Journal Title

      Medical Physics 33-8

      Pages: 2757-2764

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Influence of rib structure on detection of subtle lung nodules2006

    • Author(s)
      Mitsuru Ikeda, et al.
    • Journal Title

      European Journal of Radiology 59・1

      Pages: 49-55

    • Related Report
      2006 Annual Research Report
  • [Journal Article] The effect of patient age on contrast enhancement during CT of the pancreatobiliary region2006

    • Author(s)
      Shigeki Itoh et al.
    • Journal Title

      American Journal of Roentgenology 187・2

      Pages: 505-510

    • Related Report
      2006 Annual Research Report
  • [Journal Article] CT画像読影スクリナーの可能性とCT読影専門医の必要性について2006

    • Author(s)
      松本徹, 他
    • Journal Title

      CT検診 13

      Pages: 121-124

    • Related Report
      2006 Annual Research Report
  • [Journal Article] An effective method to verify line and point spread functions measured in computed tomography2006

    • Author(s)
      Masaki Ohkubo et al.
    • Journal Title

      Medical Physics 33・8

      Pages: 2757-2764

    • Related Report
      2006 Annual Research Report
  • [Journal Article] CT画像系において測定されたline spread function (LSF) および point spread function (PSF)の精度評価法に関する研究2006

    • Author(s)
      國井正之, 他
    • Journal Title

      医学物理 26

      Pages: 57-64

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Conversion factor for CT dosimetry to assess patient dose using a 256-slice CT-scanner2006

    • Author(s)
      Shinichirou Mori et al.
    • Journal Title

      British Journal of Radiolgy 79・947

      Pages: 888-892

    • Related Report
      2006 Annual Research Report
  • [Journal Article] 期待されるCADの特性と人との相性2006

    • Author(s)
      松本徹, 他
    • Journal Title

      臨床核医学 39・4

      Pages: 50-52

    • Related Report
      2006 Annual Research Report
  • [Journal Article] コーンビームCT用ヒール効果補償フィルタの開発2006

    • Author(s)
      森慎一郎, 他
    • Journal Title

      放射線科学 49・4

      Pages: 113-122

    • Related Report
      2006 Annual Research Report
  • [Journal Article] A method of clustering observers with different visual characteristics2006

    • Author(s)
      Takanaga Niimi et al.
    • Journal Title

      European Journal of Radiology 57・1

      Pages: 158-161

    • Related Report
      2005 Annual Research Report
  • [Journal Article] The application of Markov theory to contrast- detail analysis2006

    • Author(s)
      Kuniharu Imai et al.
    • Journal Title

      Academic Radiology 13・2

      Pages: 152-158

    • Related Report
      2005 Annual Research Report
  • [Journal Article] A study on the performance evaluation of computer-aided diagnosis for detecting pulmonary nodules for the various CT reconstruction2006

    • Author(s)
      Shinichi Wada et al.
    • Journal Title

      SPIE Medical Imaging proceedings (In Press)

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Explanation of the improvement mechanism of diagnostic performance with CAD system in interpreting CT images2006

    • Author(s)
      Toru Matsumoto et al.
    • Journal Title

      SPIE Medical Imaging proceedings (In Press)

    • Related Report
      2005 Annual Research Report
  • [Journal Article] A proposal of the diagnosis-dynamic characteristics(DDC) model describing the relation between search time and confidence levels and an application for ROC curve generation from a dichotomous judgment2006

    • Author(s)
      Toru Matsumoto et al.
    • Journal Title

      SPIE Medical Imaging proceedings (In Press)

    • Related Report
      2005 Annual Research Report
  • [Journal Article] A method of accuracy evaluation of line spread function(LAF) and point spread function(PSF) measured in the computed tomography2006

    • Author(s)
      Shinichi Wada et al.
    • Journal Title

      SPIE Medical Imaging proceedings (In Press)

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Comparison of patient doses in 256-slice CT and 16-Slice CT scanners2006

    • Author(s)
      Shinichirou Mori et al.
    • Journal Title

      British Journal of Radiolgy 79・937

      Pages: 56-61

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Enlarged longitudinal dose profiles in cone・beam CT and the need for modified dosimetry2005

    • Author(s)
      Shinichiro Mori, et al.
    • Journal Title

      Medical Physics 32-4

      Pages: 1061-1069

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Enlarged longitudinal dose profiles in cone-beam CT and the need for modified dosimetry2005

    • Author(s)
      Shinichiro Mori, et al
    • Journal Title

      Medical Physics 32-4

      Pages: 1061-1069

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Chapter 4 Radiation Exposure and Risk Assessment in HRCT : International classification of HRCT for occupational and environmental respiratory disease2005

    • Author(s)
      Kanae Nishizawa, et al
    • Journal Title

      Springer, Tokyo

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] マルコフ連鎖を用いた医用画像の視覚評価法とそれに伴う新しい画像観察法(マルコフ連鎖型観察法)の考案2005

    • Author(s)
      新美孝永 他
    • Journal Title

      電子情報通信学会誌A J88-4・7

      Pages: 25-30

    • Related Report
      2005 Annual Research Report
  • [Journal Article] 極値統計学によるアーチファクトの統計解析とそれに基づく評価法-Gumbel評価法の考案2005

    • Author(s)
      今井國治 他
    • Journal Title

      電子情報通信学会技術報告 105・386

      Pages: 1-6

    • NAID

      110004018420

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Validation of the blurring of the small object on CT image determined by calculation based on three-dimensional spatial resolution2005

    • Author(s)
      Masaki Ohkubo et al.
    • Journal Title

      Japanese Journal of Medical Physics 25・3

      Pages: 132-140

    • Related Report
      2005 Annual Research Report
  • [Journal Article] 医療技術者によるCT画像読影の潜在性の評価2005

    • Author(s)
      松本徹 他
    • Journal Title

      日本放射線技術学会雑誌 61・6

      Pages: 791-799

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Enlarged longitudinal dose profiles in cone-beam CT and the need for modified dosimetry2005

    • Author(s)
      Shinichirou Mori et al.
    • Journal Title

      Medical Physics 32・4

      Pages: 1061-1069

    • Related Report
      2005 Annual Research Report
  • [Journal Article] マルコフ連鎖を用いた医用画像の視覚評価法とそれに伴う新しい画像観察法(マルコフ連鎖型画像観察法)の考案2005

    • Author(s)
      新美孝永 他
    • Journal Title

      電子情報通信学会誌A (In Press)

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Effects of monitor luminance change on observer detection performance2005

    • Author(s)
      Satoshi Hidano et al.
    • Journal Title

      Computerized Medical Imaging and Graphics 29・1

      Pages: 35-41

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Measurements and precisions of point spread function of multi-slice CT2005

    • Author(s)
      Shinichi Wada et al.
    • Journal Title

      SPIE proceedings (In Press)

    • Related Report
      2004 Annual Research Report
  • [Journal Article] An assessment of the potential for interpretation of CT images by rasiological technologists2005

    • Author(s)
      Toru Matsumoto et al.
    • Journal Title

      SPIE proceedings (In Press)

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Solitary pulmonary nodules : optimal slice thickness of high-resolution CT in differentiating malignant from benign2004

    • Author(s)
      Shingo Iwano et al.
    • Journal Title

      Clinical Imaging 28・5

      Pages: 322-328

    • Related Report
      2004 Annual Research Report
  • [Journal Article] わが国のCT検査の実態と被ばく線量推定2004

    • Author(s)
      西澤かな枝
    • Journal Title

      日本医学放射線学会雑誌 64・7・Supplement

      Pages: 3-6

    • Related Report
      2004 Annual Research Report
  • [Presentation] The CT image standardization based on the verified PSF2007

    • Author(s)
      Shinichi Wada, et al.
    • Organizer
      SPIE Medical Imaging 2007
    • Place of Presentation
      San Diego, USA
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Book] Chapter 4 Radiation Exposure and Risk Assessment in HRCT : International classification of HRCT for occupational and environmental respiratory disease2005

    • Author(s)
      Kanae Nishizawa, et al.
    • Total Pages
      145
    • Publisher
      Springer, Tokyo
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Book] Chapter 4 Radiation Exposure and Risk Assessment in HRCT : International classification of HRCT for occupational and environmental respiratory disease2005

    • Author(s)
      Kanae Nishizawa et al.
    • Total Pages
      145
    • Publisher
      Springer, Tokyo
    • Related Report
      2005 Annual Research Report
  • [Book] 低線量CTによる肺癌検診の手引き2004

    • Author(s)
      西澤かな枝(分担執筆)
    • Publisher
      金原出版
    • Related Report
      2004 Annual Research Report
  • [Publications] Miho Kojima et al.: "Usefulness of a method for changing tube current during helical scanning in multislice CT"Radiation Medicine. 21・5. 193-204 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] Mitsuru Ikeda et al.: "Theoretical Analysis of Geometrical Magnification in Digital Radiography Part 2. Geometrical Magnification in DR"MEDICAL IMAGING TECHNOLOGY. 21・4. 295-310 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] Mitsuru Ikeda et al.: "Theoretical Analysis of Geometrical Magnification in Digital Radiography Part 1. New Concept of "Pseudo-MTF" for DR"MEDICAL IMAGING TECHNOLOGY. 21・3. 229-238 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 和田真一, 他: "CT angiographyの血管描出能とPoint Spread Functionの関係"J.Thoracic CT Screening. (In press). (2004)

    • Related Report
      2003 Annual Research Report
  • [Publications] Toru Matsumoto et al.: "Method of evaluating the effectiveness of double-checking in interpreting mass screening images"Proceeding of SPIE. (In press). (2004)

    • Related Report
      2003 Annual Research Report
  • [Publications] 西澤かな枝, 他: "CT検査件数及びCT検査による集団実効線量の推定"医学放射線学会雑誌. (In press). (2004)

    • Related Report
      2003 Annual Research Report

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Published: 2003-04-01   Modified: 2018-03-28  

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