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Creation of highly functional thermal and fluids mechanism for micro cell processing

Research Project

Project/Area Number 15106004
Research Category

Grant-in-Aid for Scientific Research (S)

Allocation TypeSingle-year Grants
Research Field Thermal engineering
Research InstitutionThe University of Tokyo

Principal Investigator

KASAGI Nobuhide  The University of Tokyo, Graduate School of Engineering, Professor (80107531)

Co-Investigator(Kenkyū-buntansha) SUZUKI YUJI  The University of Tokyo, Graduate School of Engineering, Associate Professor (80222066)
SHIKAZONO Naoki  The University of Tokyo, Graduate School of Engineering, Associate Professor (30345087)
USHIDA Takashi  The University of Tokyo, Faculty of Medicine, Professor (50323522)
FUNAKAWA Katsuko  The University of Tokyo, Graduate School of Enginening, Associate Professor (90343144)
笠木 伸英  東京大学, 大学院・工学研究科, 准教授 (80107531)
Project Period (FY) 2003 – 2007
Project Status Completed (Fiscal Year 2007)
Budget Amount *help
¥128,570,000 (Direct Cost: ¥98,900,000、Indirect Cost: ¥29,670,000)
Fiscal Year 2007: ¥14,560,000 (Direct Cost: ¥11,200,000、Indirect Cost: ¥3,360,000)
Fiscal Year 2006: ¥17,680,000 (Direct Cost: ¥13,600,000、Indirect Cost: ¥4,080,000)
Fiscal Year 2005: ¥24,050,000 (Direct Cost: ¥18,500,000、Indirect Cost: ¥5,550,000)
Fiscal Year 2004: ¥30,550,000 (Direct Cost: ¥23,500,000、Indirect Cost: ¥7,050,000)
Fiscal Year 2003: ¥41,730,000 (Direct Cost: ¥32,100,000、Indirect Cost: ¥9,630,000)
KeywordsBiomedical equinment / Regenerative medicine / Thermal engineering / Fluid engineering / Micro electro mechanical system / 流体力学 / マイクロセルソータ / 再生医療 / マイクロ混合器 / マイクロ分離器 / 抗原抗体反応 / 磁性粒子 / 接着性 / 温度感受性ゲル / マイクロ生化学分析システム / セルソータ / 表面マーカ / マイクロ流路 / カオス混合 / ラミネーション混合 / 旋廻培養
Research Abstract

The objective of the present study is to develop a novel micro cell processing system for efficient mixing, labeling, sorting and transporting of cells in micro channels by using heat and fluid phenomena inherent in microscale. As a specific application, regenerative medicine using adult somatic stem cells is assumed, and cell sorting systems that can efficiently extract rare cells from cell mixture have been developed. More specifically, high-precision numerical scheme and a novel imaging methods have been developed for understanding cell/particle motions in micro channels. Specific design guiding principle for cell sorting system that can be used for future clinical application is obtained by development of MEMS fabrication technologies using new biocompatible materials and experimental evaluation of the prototype micro cell sorters.
A lamination micro mixer and an immunomagnetic cell sorting system using the mixers have been developed. We found that the throughput can be higher than previous micro cell sorters, and that processing relatively-large amount of cell samples needed for clinical use is possible when the numbering-up approach is adopted. In addition, novel adhesion-based cell sorting systems that utilize deceleration of cell rolling by antigen-antibody interaction on the wall has been proposed, and its prototype is developed. With this system, one can eliminate labeling of the target cells. We also propose a new immobilization method of antibody with amino-functionalized parylene.
Conventional cell sorting/incubation process is time consuming and requires a long time and much human resources. Cell sorting methods proposed in the present study based on characteristics of microscale heat and fluid flows will reduce cost and analysis time of cell sorting, and eventually make contribution to advances of regenerativie medicine.

Report

(6 results)
  • 2007 Annual Research Report   Final Research Report Summary
  • 2006 Annual Research Report
  • 2005 Annual Research Report
  • 2004 Annual Research Report
  • 2003 Annual Research Report
  • Research Products

    (136 results)

All 2008 2007 2006 2005 2004 2003 Other

All Journal Article (88 results) (of which Peer Reviewed: 42 results) Presentation (31 results) Book (4 results) Patent(Industrial Property Rights) (8 results) Publications (5 results)

  • [Journal Article] Adhesion-Based Cell Sorter with Antibody-Immobilized Amino-Functionalized Parylene Surface2008

    • Author(s)
      J.Miwa
    • Journal Title

      J. Microelectromech. Syst. 17(In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Characteristics of a Scaffold-Free Articular Chodrocyte Plate Grown in Rotational Culture2008

    • Author(s)
      T.Nagai
    • Journal Title

      Tissue Engineering 掲載確定(In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Optimization of allograft implantation using scaffold-free chondrocvtes plate2008

    • Author(s)
      T.Nagai
    • Journal Title

      Tissue Engineering 掲載確定(In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Scaffold-free cartilage by rotational culture for tissueengineering2008

    • Author(s)
      K. Furukawa
    • Journal Title

      J. Biotechnology 133

      Pages: 134-145

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Adhesion-Based Cell Sorter with Antibody-Immobilized Amino-Functionalized Parylene Surface2008

    • Author(s)
      J. Miwa
    • Journal Title

      J. Microelectromech. Syst (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Characteristics of a Scaffold-Free Articular Chodrocyte Plate Grown in Rotational Culture2008

    • Author(s)
      T. Nagai
    • Journal Title

      Tissue Engineering (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Optimization of allograft implantation using scaffold-free chondrocytes plate2008

    • Author(s)
      T. Nagai
    • Journal Title

      Tissue Engineering (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Cell sorting system by modified cone plate type rheometer2008

    • Author(s)
      K. Furukawa
    • Journal Title

      Jpn. J Clinical Medicine (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Scaffold-free cartilage by rotational culture for tissue engineering2008

    • Author(s)
      K. Furukawa
    • Journal Title

      J Biotechnology 133 (1)

      Pages: 134-145

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Adhesion-based Cell Sorter with Amino-fUnctionalized Parylene Surface2008

    • Author(s)
      Miwa, J., Suzuki, Y., and Kasagi, N.
    • Journal Title

      J.Microelectromech.Syst 17in press(掲載確定)

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Characteristics of a Scaffold-Free Articular Chodrocyte Plate Grown in Rotational Culture2008

    • Author(s)
      T. Nagai, K. S. Furukawa, M. Sato, T. Ushidaand J. Mochida
    • Journal Title

      Tissue Engineering (in press)(掲載確定)

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Optimization of allograft implantation using scaffold-free chondrocytes plate2008

    • Author(s)
      T. Nagai, K. S. Furukawa, M. Sato, T. Ushida and J. Mochida
    • Journal Title

      Tissue Engineering (in press)(掲載確定)

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cell sorting system by modified cone plate type rheometer2008

    • Author(s)
      K. Furukawa, T. Tateishi, T. Tamaki and T. Ushida
    • Journal Title

      Jpn.J Clinical Medicine (in press)

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Scafffold-free cartilage by rotational culture for tissue engineering2008

    • Author(s)
      K. Furukawa, K. Imura, T. Tateishi and T. Ushida
    • Journal Title

      J Biotechnology 133(1)

      Pages: 134-145

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] コーンプレート型せん断応力負荷装置による細胞ソーティングモデルの構築2007

    • Author(s)
      古川克子
    • Journal Title

      日本臨床バイオメカニクス学会誌 28

      Pages: 61-65

    • NAID

      10027910625

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Feasibility of noninvasicve evaluation of biophysical properties of tissue-engineered cartilage by using quantitative MRI2007

    • Author(s)
      S. Miyata
    • Journal Title

      J Biomech. 40

      Pages: 2990-2998

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Feasibility of noninvasicve evaluation of biophysical properties of tissue-engineered cartilage by using quantitative MRI2007

    • Author(s)
      S. Miyata
    • Journal Title

      J Biomech 40 (13)

      Pages: 2990-2998

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Feasibility of noninvasicve evaluation of biophysical properties of tissue-engineered cartilage by using quantitative MRI2007

    • Author(s)
      S. Miyata, T. Numano, K. Homma, T. Tateishi and T. Ushida
    • Journal Title

      J Biomech 40(13)

      Pages: 2990-2998

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Numerical Simulation of Gas-Liquid Two-Phase Flow and Convective Heat Transfer in a Micro Tube2007

    • Author(s)
      Fukagata, K, Kasagi, N., Ua-arayapom, P., Himeno, T.
    • Journal Title

      International Journal of Heat and Fluid Flow 28・l

      Pages: 72-82

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Regeneration of the Esophagus Using Gastric Acellular Matrix : an Experimental Study in a Rat Model2007

    • Author(s)
      Urita, Y., Komuro, H., Chen, T., Shinya, M., Kaneko, S., Kaneko, M., Ushida, T.
    • Journal Title

      Pediatric Surgery International 23・1

      Pages: 21-26

    • NAID

      10027854847

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Development of High-Speed Micro Scanning PIV Using a Rotating Disk2006

    • Author(s)
      K. P. Angele
    • Journal Title

      Meas. Sci. Tech. 17

      Pages: 1639-1646

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Impact of convective flow on the cellular uptake and transfection activity of lipoflex and adenovirus2006

    • Author(s)
      T. Fujiwara
    • Journal Title

      Biol. Pharm. Bull. 29

      Pages: 1511-1515

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Effect of structure degeneration by enzymatic treatment on viscoelasticity of articular cartilage2006

    • Author(s)
      S. Miyata
    • Journal Title

      Jap. Soc. Clinical Medicine 27

      Pages: 23-27

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Continuous Visualization of Morphological Changes in Endothelial Cells in Response to Cyclic Stretch2006

    • Author(s)
      S. Iwayoshi
    • Journal Title

      JSME International Journal Ser. C 49

      Pages: 545-555

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] NMRスペクトロスコピーによる再生軟骨の組織評価法2006

    • Author(s)
      宮田昌悟
    • Journal Title

      日本機械学会論文集(C) 72

      Pages: 223-228

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Development of High-Speed Micro Scanning PIV Using a Rotating Disk2006

    • Author(s)
      K. P. Angele
    • Journal Title

      Meas. Sci. Tech. Vol.17, No.7

      Pages: 1639-1646

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Impact of convective flow on the cellular uptake and transfection activity of lipoflex and adenovirus"2006

    • Author(s)
      T. Fujiwara
    • Journal Title

      Biol. Pharm. Bull 29 (7)

      Pages: 1511-1515

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Continuous Visualization of Morphological Changes in Endothelial Cells in Response to Cyclic Stretch2006

    • Author(s)
      S. Iwayoshi
    • Journal Title

      JSME International Journal Ser. C 49 (2)

      Pages: 545-555

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Development of High-Speed Micro Scanning PIV Using a Rotating Disk2006

    • Author(s)
      Angele, K.P., Suzuki, Y., Miwa, J., Kasagi, N.
    • Journal Title

      Measurement Science and Technology 17・7

      Pages: 1639-1646

    • Related Report
      2006 Annual Research Report
  • [Journal Article] The state of the Art of Nanobioscience in Japan2006

    • Author(s)
      Ueno, S., Ando, J., Fujita, H., Sugawara, T., Jimbo, Y., Itaka, K., Kataoka K., Ushida, T.
    • Journal Title

      IEEE Transactions on Nanobioscience 5・1

      Pages: 54-65

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Continuous Visualization of Morphological Cahnges in Endothelial Cells in Response to Cyclic Stretch2006

    • Author(s)
      Iwayoshi, S., Furukawa, K., Ushida, T.
    • Journal Title

      JSME International Journal : C 49・2

      Pages: 545-555

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Impact of Convective Flow on the Cellular Uptake and Transfection Activity of Lipoplex and Adenovirus2006

    • Author(s)
      Fujiwara, T., Akita, H., Furukawa, K., Ushida, T., Mizuguchi, H., Harashima, H.
    • Journal Title

      Biological & Pharmaceutical Bulletin 29・7

      Pages: 1511-1515

    • NAID

      110005602335

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Assessment of Fixed Charge Density in Regenerated Cartilage by Gd-DTPA-Enhanced MRI2006

    • Author(s)
      Miyata, S., Homma, K., Numano, T., Furukawa, K., Tateishi, T., Ushida, T.
    • Journal Title

      Magnetic Resonance in Medical Science 5・2

      Pages: 73-78

    • NAID

      10018258510

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Lamination Micro Mixer for Micro-Immunomagnetic Cell Sorting2005

    • Author(s)
      W.-H. Tan
    • Journal Title

      JSME Int. J., Ser. C Vol.48,No.4

      Pages: 425-435

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Cartilaginous Tissue: Criteria for Classification Between Hyaline Cartilage and Fibrocartilage Based on Mechanical Function2005

    • Author(s)
      S. Miyata
    • Journal Title

      JSME International Journal Ser. C 48

      Pages: 547-554

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] 骨再生における多孔質セラミックスの新規な利用方法の開発2005

    • Author(s)
      宮内俊輔
    • Journal Title

      粉体粉末冶金 52

      Pages: 351-355

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] 静水圧負荷下での間接軟骨細胞の3次元長期培養のための培養系の開発2005

    • Author(s)
      川西誠
    • Journal Title

      臨床バイオメカニクズ学会誌 26

      Pages: 1-5

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Spontaneous Formation of Blood-Compatible Surfaces on Hydrophilic Polymers: Surface Enrichment of a Block Copolymer with a Water-Soluble Block2005

    • Author(s)
      A. Oyane
    • Journal Title

      Adv. Mater. 17

      Pages: 2329-2332

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Reduced platelet adhesion to titanium metal coated with apatite, albumin-apatite composite or laminin-apatite composite2005

    • Author(s)
      M. Uchida
    • Journal Title

      Biomaterials 26

      Pages: 6924-6931

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Dynamic visco-elastic property of tissue-engineered cartilage and assessment with biphasic theory2005

    • Author(s)
      S. Miyata
    • Journal Title

      Jap Soc Clinical Medicine 26

      Pages: 7-11

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Lamination Micro Mixer for Micro-Immunomagnetic Cell Sorting2005

    • Author(s)
      W.-H. Tan
    • Journal Title

      JSME Int. J., Ser. C Vol.48, No.4

      Pages: 425-435

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Cartilaginous Tissue : Criteria for Classification Between Hyaline Cartilage and Fibrocartilage Based on Mechanical Function2005

    • Author(s)
      S. Miyata
    • Journal Title

      JSME International Journal Ser. C 48 (4)

      Pages: 547-554

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Spontaneous Formation of Blood-Compatible Surfaces on Hydrophilic Polymers : Surface Enrichment of a Block Copolymer with a water-Soluble Block2005

    • Author(s)
      A. Oyane
    • Journal Title

      Adv. Mater 17

      Pages: 2329-2332

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Reduced platelet adhesion to titanium metal coated with apatite, albumin-apatite composite or laminin-apatite composite"2005

    • Author(s)
      M. Uchida
    • Journal Title

      Biomaterials 26

      Pages: 6924-693

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Lamination Micro Mixer for Micro-immunomagnetic Cell Sorting2005

    • Author(s)
      Tan, W.-H., Suzuki, Y., Kasagi, N., Shikazono, N., Furukawa, K., Ushida, T.
    • Journal Title

      JSME Intermational Series C 48・4

      Pages: 425-435

    • Related Report
      2005 Annual Research Report
  • [Journal Article] 骨再生における多孔室セラミックスの新規な利用方法の開発2005

    • Author(s)
      宮内俊輔, 古川克子, 梅津義一, 尾関泰之, 牛田多加志, 立石哲也
    • Journal Title

      粉体粉末冶金 52・5

      Pages: 351-355

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Reduced plate adhesion to titanium metal coated with apatite, albumin-apatite composite or laminin-apatite composite2005

    • Author(s)
      Uchida, M., Ito, A., Furukawa, K.S., Nakamura, K., Onimura, Y., Oyama, A., Ushida, T., Tamaki, T., Tateishi, T.
    • Journal Title

      Biomaterials 26

      Pages: 6924-6931

    • Related Report
      2005 Annual Research Report
  • [Journal Article] 培養軟骨組織の動的粘弾性および二相理論力学モデルによる解析2005

    • Author(s)
      宮田昌悟, 古川克子, 牛田多加志, 立石哲也
    • Journal Title

      日本臨床バイオメカニクス学会誌 26

      Pages: 7-11

    • NAID

      10017097026

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Influence of structure and composition on dynamic viscoelastic property of cartilaginous tissue: Criteria for classification between hyaline cartilage and fibrocartilage based on mechanical function2005

    • Author(s)
      Miyata, S., Tateishi, T., Furukawa, K., Ushida, T.
    • Journal Title

      JSME Intemational Series C 48

      Pages: 547-554

    • NAID

      110004826675

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Spontaneously formed blood compatible surfaces on hydrophobic polymer surface enrichment of a block copolymer with a water-soluble block2005

    • Author(s)
      Ohyane, A., Ishizone, T., Ushida, M., Furukawa, K., Ushida, T., Yokoyama, H。
    • Journal Title

      Advanced Materials 17

      Pages: 2329-2332

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Fabrication of microstructures in photsensitive biodegradable polymers for tissue engineering applications2004

    • Author(s)
      E. Leclerc
    • Journal Title

      Biomaterials 25

      Pages: 4683-4690

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Effect on liver cells of stepwise microstructures fabricated in a photosensitive biodegradable polymer by soft lithography2004

    • Author(s)
      E. Leclerc
    • Journal Title

      Material Science & Engineering C 24

      Pages: 349-354

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] ヒト血小板による医用材料の抗血栓性評価2004

    • Author(s)
      古川克子
    • Journal Title

      日本臨床バイオメカニクス学会誌 25

      Pages: 49-54

    • NAID

      10014186356

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Static and dynamic mechanical properties of extracellular matrix synthesized by cultured chondrocytes2004

    • Author(s)
      S. Miyata
    • Journal Title

      Material Science & Engineering C 24

      Pages: 425-429

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] 細胞間相互作用を利用した軟骨様組織のin vitro再構築2004

    • Author(s)
      井村勝亮
    • Journal Title

      日本臨床バイオメカニクス学会誌 25

      Pages: 75-78

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Bone tissue engineering based on bead- cell sheets composed of calcium phosphate beads and bone marrow cells2004

    • Author(s)
      K. Furukawa
    • Journal Title

      Material Science & Engineering C 24

      Pages: 437-440

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Efficacy of topical hyperbaric oxygen for refractory foot ulcer2004

    • Author(s)
      Y. Ishii
    • Journal Title

      Material Science & Engineering C 24

      Pages: 329-332

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Aggregate formation of bone marrow stromal cells by rotation culture2004

    • Author(s)
      H. Suenaga
    • Journal Title

      Material Science & Engineering C 24

      Pages: 421-424

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Regeneration of cartilage tissue by combination of canine chondrocyte and a hybrid mesh scaffold2004

    • Author(s)
      G. Chen
    • Journal Title

      Material Science & Engineering C 24

      Pages: 373-378

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Basic fibroblast growth factor supports in vitro chondrogenesis of bone marrow-derived mesenchymal stem cells from patients with osteoarthritis2004

    • Author(s)
      H. Akaogi
    • Journal Title

      Material Science & Engineering C 24

      Pages: 403-406

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] The effect of coculture of chondrocytes with mesenchymal stem cells on their cartilaginous phenotype in vitro2004

    • Author(s)
      K. Tsuchiya
    • Journal Title

      Material Science & Engineering C 24

      Pages: 391-396

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] New type of biodegradable porous scaffolds for tissue-engineered articular cartilage2004

    • Author(s)
      M. Kawanishi
    • Journal Title

      Material Science & Engineering C 24

      Pages: 431-435

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Identification of membrane and secreted proteins in anterior cruciate ligament derived cells using "signal-sequence-trap", a retrovirus-mediated expression screening method2004

    • Author(s)
      S. Miyaki
    • Journal Title

      Material Science & Engineering C 24

      Pages: 397-401

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Evaluation of PLLA-collagen hybrid sponge as a scaffold for cartilage tissue engineering2004

    • Author(s)
      T. Sato
    • Journal Title

      Material Science & Engineering C 24

      Pages: 365-372

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Effect of mechanical stretch on TGF-1 expression of C2C12 myogenic cells2004

    • Author(s)
      T. Akimoto
    • Journal Title

      Material Science & Engineering C 24

      Pages: 387-389

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] A chaotic mixer for magnetic beads-based micro cell sorter2004

    • Author(s)
      H. Suzuki
    • Journal Title

      J. Microelectromech. Sys. 13

      Pages: 779-790

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] 抗血栓性材料の評価系の開発2004

    • Author(s)
      古川克子
    • Journal Title

      バイオレオロジー学会誌 18

      Pages: 135-142

    • NAID

      130001932245

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] 血液適合性材料の評価2004

    • Author(s)
      古川克子
    • Journal Title

      日本機械学会学会誌 107

      Pages: 130-132

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Fabrication of microstructures in photsensitive biodegradable polymers for tissue engineering applications2004

    • Author(s)
      E. Leclerc
    • Journal Title

      Biomaterials 25 (19)

      Pages: 4683-4690

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Effect on liver cells of stepwise microstructures fabricated in a photosensitive biodegradable polymer by soft lithography2004

    • Author(s)
      E. Leclerc
    • Journal Title

      Material Science & Engineering C 24 (3)

      Pages: 349-354

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Static and dynamic mechanical-properties of extracellular matrix synthesized by cultured chondrocytes"2004

    • Author(s)
      S. Miyata
    • Journal Title

      Material Science & Engineering C 24 (3)

      Pages: 425-429

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Bone tissue engineering based on bead- cell sheets composed of calcium phosphate beads and bonemarrow cells2004

    • Author(s)
      K. Furukawa
    • Journal Title

      Material Science & Engineering C 24 (3)

      Pages: 437-440

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Efficacy of topical hyperbaric oxygen for refractory foot ulcer.2004

    • Author(s)
      Y. Ishii
    • Journal Title

      Material Science & Engineering C 24 (3)

      Pages: 329-332

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Aggregate formation of bone marrow stromal cells by rotation culture2004

    • Author(s)
      H. Suenaga
    • Journal Title

      Material Science & Engineering C 24 (3)

      Pages: 421-424

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Bone tissue engineering based on bead-cell sheets composed of calcium phosphate beads and bone marrow cells2004

    • Author(s)
      K. S. Furukawa
    • Journal Title

      Material Science & Engineering C 24 (3)

      Pages: 437-440

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Regeneration of cartilage tissue by combinatioi of canine chondrocyte and a hybrid mesh scaffold2004

    • Author(s)
      G. Chen
    • Journal Title

      Material Science & Engineering C 24 (3)

      Pages: 373-378

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Basic fibroblast growth factor supports in vitro chondrogenesis of bone marrow-derived mesenchymal stem cells from patients with osteoarthritis2004

    • Author(s)
      H. Akaogi
    • Journal Title

      Material Science & Engineering C 24 (3)

      Pages: 403-406

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] The effect of coculture of chondrocytes with mesenchymal stem cells on their cartilaginous phenotype in vitro2004

    • Author(s)
      K. Tsuchiya
    • Journal Title

      Material Science & Engineering C 24(3)

      Pages: 391-396

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] New type of biodegradable porous scaffolds for tissue- engineered articular cartilage2004

    • Author(s)
      M. Kawanishi
    • Journal Title

      Material Science & Engineering C 24 (3)

      Pages: 431-435

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] "Identification of membrane and secreted proteins in anterior cruciate ligament derived cells using "signal-sequence-trap", a retrovirus- mediated expression screening method"2004

    • Author(s)
      S. Miyaki
    • Journal Title

      Material Science & Engineering C 24(3)

      Pages: 397-401

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Evaluation of PLLA-collagen hybrid sponge as a scaffold for cartilage tissue engineering2004

    • Author(s)
      T. Sato
    • Journal Title

      Material Science & Engineering C 240

      Pages: 365-372

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Effect of mechanical stretch on TGF-l expression of C2C12 myogenic cells2004

    • Author(s)
      T. Akimoto
    • Journal Title

      Material Science & Engineering C 240

      Pages: 387-389

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] A chaotic mixer for magnetic beads-based micro cell sorter2004

    • Author(s)
      H. Suzuki
    • Journal Title

      J. Microelectromech.sys. Vol.13, No.5

      Pages: 779-790

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Formation of normal bone marrow stromal cell aggregates by rotation culture2004

    • Author(s)
      Hideyuki SUENAGA, Katsuko S FURUKAWA, et al.
    • Journal Title

      Materials Science & Engineering C 24(3)

      Pages: 421-424

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Bone tissue engineering based on bead-cell sheets composed of calcium phosphate beads and bone marrow cells.2004

    • Author(s)
      Katsuko S Furukawa, Shunsuke Miyauchi et al.
    • Journal Title

      Material Science and Engineering C 24(3)

      Pages: 2004-2004

    • Related Report
      2004 Annual Research Report
  • [Journal Article] A Chaotic Mixer for Magnetic Beads-Based Micro Cell Sorter2004

    • Author(s)
      Suzuki, H., Ho., C, -M., Kasagi, N.
    • Journal Title

      Journal of Microelectromechanical Systems 13(5)

      Pages: 779-790

    • Related Report
      2004 Annual Research Report
  • [Journal Article] 細胞間相互作用を利用した軟骨様組織のin vitro再構築

    • Author(s)
      井村勝亮, 古川克子
    • Journal Title

      日本臨床バイオメカニクス学会誌 (印刷中)

    • NAID

      10014186401

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Novel bone graft model using bead-cell sheets composed of tricalcium phosphate beads and bone marrow cells.

    • Author(s)
      Shunsuke Miyauchia^a, Katsuko S, Fumkawa et al.
    • Journal Title

      Materials Science & Engineering C (In press)

    • Related Report
      2004 Annual Research Report
  • [Presentation] コーンプレート型せん断応力負荷装置を用いた細胞ソーティングモデルの構築2008

    • Author(s)
      吉田圭太
    • Organizer
      日本機械学会関東支部第14期総会講演会
    • Place of Presentation
      東京
    • Year and Date
      2008-03-14
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Adhesion-Based Cell Sorter with Antiboday-Immobilized Amino-Functionalized Parylene Surface2007

    • Author(s)
      J. Miwa
    • Organizer
      IEEE Int. Conf. MEMS 2007, Kobe
    • Place of Presentation
      神戸
    • Year and Date
      2007-01-22
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Adhesion-Based Cell Sorter with Antibody-Immobilized Amino-Functionalized Parylene Surface2007

    • Author(s)
      J. Miwa
    • Organizer
      IEEE Int. Conf. MEMS
    • Place of Presentation
      Kobe
    • Year and Date
      2007-01-22
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Mixing enhancement in a lamination micro mixer for cell sorting2006

    • Author(s)
      C. Chaktranond
    • Organizer
      20th Conf. Mech. Eng. Network of Thailand, Nakhon, Thailand
    • Place of Presentation
      Nakhon, Thailand
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Evaluation of Lamination Micro Mixer for Micro Immunomagnetic Cell Sorter2006

    • Author(s)
      H. Inokuchi
    • Organizer
      Int. Conf. Microtechnologies in Medicine and Biology, Okinawa
    • Place of Presentation
      万国津梁館、沖縄
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Evaluation of Cell Velocity Regulation in a Microfabricated Adhesion-Based Cell Separation Device2006

    • Author(s)
      J. Miwa
    • Organizer
      Int. Conf. Microtechnologies in Medicine and Biology, Okinawa
    • Place of Presentation
      万国津梁館、沖縄
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 免疫磁気細胞分離に用いるラミネーション・マイクロミキサーの性能評価2006

    • Author(s)
      井口 裕道
    • Organizer
      第43回日本伝熱シンポジウム
    • Place of Presentation
      名古屋
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Mixing enhancement in a lamination micro mixer for cell sorting2006

    • Author(s)
      C. Chaktranond
    • Organizer
      20th Conf. Mech. Eng. Network of Thailand
    • Place of Presentation
      Nakhon, Thailand
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Evaluation of Lamination Micro Mixer for Micro Immunomagnetic Cell Sorter2006

    • Author(s)
      H. Inokuchi
    • Organizer
      2006 Int. Conf. Microtechnologies in Medicine and Biology
    • Place of Presentation
      Okinawa
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Evaluation of Cell Velocity Regulation in a Microfabricated Adhesion-Based Cell Separation Device2006

    • Author(s)
      J. Miwa
    • Organizer
      2006 Int. Conf. Microtechnologies in Medicine and Biology
    • Place of Presentation
      Okinaw
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Micro Magnetic Separator for Stem Cell Sorting System2005

    • Author(s)
      H. Inokuchi
    • Organizer
      22nd Sensor Symp., Tokyo
    • Place of Presentation
      東京
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Adhesion-based cell velocity regulation in an antibody-coated micro column for stem cell separation2005

    • Author(s)
      J.Miwa
    • Organizer
      μTAS 2005, Boston
    • Place of Presentation
      ボストン、米国
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Development of high-speed micro scanning PIV2005

    • Author(s)
      K.P. Angele
    • Organizer
      6th Int. Symp. Particle Image Velocimetry, Pasadena
    • Place of Presentation
      Pasadena, U.S.A.
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] DeveloPment of micro immunoreaction-based cell sorter for regenerative medicine2005

    • Author(s)
      J. Miwa
    • Organizer
      1st Int. Conf. Bio-Nano-Informatics (BNI) Fusion, Marina del Rey
    • Place of Presentation
      Marina del Ray, California, U.S.A.
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Micro Magnetic Separator for Stem Cell Sorting System2005

    • Author(s)
      H. Inokuchi
    • Organizer
      22nd Sensor Symp
    • Place of Presentation
      Tokyo
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Adhesion-based cell velocity regulation in an antibody-coated micro column for stem cell separation2005

    • Author(s)
      J. Miwa
    • Organizer
      μTAS 2005
    • Place of Presentation
      Bos ton
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Development of high-speed micro scanning PIV2005

    • Author(s)
      K. P. Angele
    • Organizer
      6th Int. Symp. Particle Image Velocimetry
    • Place of Presentation
      Pasadena, U. S. A
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Development of micro immunoreaction-based cell sorter for regenerative medicine2005

    • Author(s)
      J. Miwa
    • Organizer
      1st Int. Conf. Bio-Nano-Informatics (BNI) Fusion
    • Place of Presentation
      Marina del Rey, U. S. A
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Mixing enhancement in a micro serpentine conduit for cell sorting2004

    • Author(s)
      C. Chaktranond
    • Organizer
      5th Int. Conf. on Multiphase Flow, Yokohama
    • Place of Presentation
      横浜
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Lagrangian chaos in a micro serpentine mixer for immunomagnetic cell sorting2004

    • Author(s)
      K. Fukagata
    • Organizer
      Transport Phenomena in Micro and Nanodevices, Kona Coast
    • Place of Presentation
      Hawaii, U.S.A.
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Development of novel micro mixer and its application to μ-immunomagnetic cell sorter2004

    • Author(s)
      W. -H. Tan
    • Organizer
      8th Int. Conf. Miniaturised Systems for Chemistry and Life Sciences (μTAS2004), Malmo, Sweden
    • Place of Presentation
      Malmo, Sweden
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] セルソータ用マイクロ混合器における磁性粒子運動の数値シミュレーション2004

    • Author(s)
      ジャークタノンチャイナロン
    • Organizer
      第18回数値流体力学シンポジウム講演論文集, 東京
    • Place of Presentation
      東京
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Mixing enhancement in a micro serpentine conduit for cell sorting2004

    • Author(s)
      C. Chaktranond
    • Organizer
      5th Int. Conf. on Multiphase Flow
    • Place of Presentation
      Yokoham
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Lagrangian chaos in a micro serpentine mixer for immunomagnetic cell sorting2004

    • Author(s)
      K. Fukagata
    • Organizer
      Transport Phenomena in Micro and Nanodevices
    • Place of Presentation
      Kona Coast, U. S. A
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Development of novel micro mixer and its application to μ-immunomagnetic cell sorter2004

    • Author(s)
      W.-H. Tan
    • Organizer
      8th Int. Conf. Miniaturised Systems for Chemistry and Life Sciences (μTAS2004)
    • Place of Presentation
      Malmo, Sweden
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Particle tracking velocimetry Measurement of chaotic mixing in a micro mixer2003

    • Author(s)
      H. Suzuki
    • Organizer
      Int. Symp. Micro-Mechanical Engineering (ISMME2003), Tsuchiura
    • Place of Presentation
      土浦
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Chaotic mixing of magnetic beads in micro cell separator2003

    • Author(s)
      H. Suzuki
    • Organizer
      3rd Int. Symp. on Turbulence and Shear Flow Phenomena, Sendai
    • Place of Presentation
      仙台
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 磁性粒子を利用したマイクロ細胞分離システムのためのカオス混合器2003

    • Author(s)
      鈴木 宏明
    • Organizer
      東大バイオチップシンポジウム
    • Place of Presentation
      東京
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 生化学分析用マイクロ混合器における固体粒子運動のラグランジュ的数値解析2003

    • Author(s)
      田中 博人
    • Organizer
      日本混相流学会年会講演会2003
    • Place of Presentation
      大阪
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Particle tracking velocimetry measurement of chaotic mixing in a micro mixer2003

    • Author(s)
      H. Suzuki
    • Organizer
      Int. Symp. Micro-Mechanical Engineering (ISMME2003)
    • Place of Presentation
      Tsuchiura
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Chaotic mixing of magnetic beads in micro cell separator2003

    • Author(s)
      H. Suzuki
    • Organizer
      3rd Int. Symp. on Turbulence and Shear Flow Phenomena
    • Place of Presentation
      Sendai
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Book] 機械工学便覧,デザイン編 生体工学 ティッシュエンジニアリング2007

    • Author(s)
      牛田多加志, 立石哲也, 古川克子
    • Publisher
      丸善
    • Related Report
      2006 Annual Research Report
  • [Book] 再生医療のためのバイオエンジニアリング,メカニカルエンジニアリングと軟骨再生,血管再生2007

    • Author(s)
      牛田多加志, 古川克子
    • Publisher
      コロナ社
    • Related Report
      2006 Annual Research Report
  • [Book] 磁性ビーズのバイオ・環境技術への応用展開(半田, 阿部, 野田編)のうち「マイクロ・セルソーティング技術」2006

    • Author(s)
      三輪潤一, 鈴木雄二, 笠木伸英
    • Publisher
      シーエムシー出版(印刷中)
    • Related Report
      2005 Annual Research Report
  • [Book] 図解再生医療工学,第3章 再生医療のキーテクノロジー技術編6「三次元培養」(立石哲也編)2005

    • Author(s)
      古川克子
    • Publisher
      工業調査会出版(印刷中)
    • Related Report
      2004 Annual Research Report
  • [Patent(Industrial Property Rights)] 特許2006

    • Inventor(s)
      鈴木雄二ら
    • Industrial Property Rights Holder
      東京大学総長
    • Industrial Property Number
      2006-151848
    • Filing Date
      2006-05-31
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Patent(Industrial Property Rights)] アミノ基を有する被膜を表面に有する基体の製造方法2006

    • Inventor(s)
      鈴木雄二, 笠木伸英, 三輪潤一, 吉岡宏司郎, 柴山健一, 井上崇
    • Industrial Property Rights Holder
      東京大学総長
    • Industrial Property Number
      2006-151848
    • Filing Date
      2006-05-31
    • Related Report
      2006 Annual Research Report
  • [Patent(Industrial Property Rights)] 特許2005

    • Inventor(s)
      鈴木雄二ら
    • Industrial Property Rights Holder
      東京大学総長
    • Industrial Property Number
      2005-268837
    • Filing Date
      2005-09-15
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Patent(Industrial Property Rights)] 層内物質状態測定装置2005

    • Inventor(s)
      鈴木雄二, 笠木伸英, 中村健一, 安木政史
    • Industrial Property Rights Holder
      国立大学法人東京大学
    • Industrial Property Number
      2005-268837
    • Filing Date
      2005-09-15
    • Related Report
      2005 Annual Research Report
  • [Patent(Industrial Property Rights)] 特許2004

    • Inventor(s)
      笠木伸英ら
    • Industrial Property Rights Holder
      東京大学総長
    • Industrial Property Number
      2004-186321
    • Filing Date
      2004-06-24
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Patent(Industrial Property Rights)] 特許2004

    • Inventor(s)
      笠木伸英ら
    • Industrial Property Rights Holder
      東京大学総長
    • Industrial Property Number
      2004-186381
    • Filing Date
      2004-06-24
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Patent(Industrial Property Rights)] マイクロミキサー,及び混合方法2004

    • Inventor(s)
      笠木 伸英
    • Industrial Property Rights Holder
      東京大学長
    • Industrial Property Number
      2004-186321
    • Filing Date
      2004-06-24
    • Related Report
      2004 Annual Research Report
  • [Patent(Industrial Property Rights)] 細胞分離装置,及び細胞分離方法2004

    • Inventor(s)
      笠木 伸英
    • Industrial Property Rights Holder
      東京大学長
    • Industrial Property Number
      2004-186381
    • Filing Date
      2004-06-24
    • Related Report
      2004 Annual Research Report
  • [Publications] Furukawa, K.S., Suenaga, H.Toita, K., Numata, A., Tanaka, J., Ushida, T., Sakai, Y, Tateishi, T.: "Rapid and large-scale formation of chondrocyte aggregates by rotational culture"Cell Transplantation. 12巻・5号. 475-479 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 鈴木宏明, 笠木伸英, Ho, Chih-Ming: "磁性粒子を利用したカオス的マイクロ混合器"日本機械学会論文集B編. 69巻・688号. 2626-2632 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] Suenaga, H., Furukawa, K.S., Ushida, T., Takato, T., Tateishi, T.: "Formation of normal bone marrow stromal cell aggregates by rotation culture"Materials Science & Engineering C. (In press).

    • Related Report
      2003 Annual Research Report
  • [Publications] 古川克子, 牛田多加志, 末永英之, 酒井康行, 立石哲也: "軟骨再生のための旋回培養による3次元凝集塊の大量形成"日本臨床バイオメカニクス学会誌. 24巻. 39-44 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 古川克子(分担執筆): "立石哲也編,図解再生医療工学.第3章 再生医療のキーテクノロジー技術編6「三次元培養」"工業調査会出版(印刷中).

    • Related Report
      2003 Annual Research Report

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Published: 2003-04-01   Modified: 2016-04-21  

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