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Studies on gene expression concerning exercise-induced differentiation or metabolic change in skeletal muscle

Research Project

Project/Area Number 15200048
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Research Field Sports science
Research InstitutionUniversity of Tsukuba

Principal Investigator

TAKEMASA Tohru (2004-2006)  University of Tsukuba, Graduate School of Comprehensive Human Sciences, Associate Professor, 大学院人間総合科学研究科, 助教授 (50236501)

芳賀 脩光 (2003)  筑波大学, 体育科学系, 教授 (80093102)

Co-Investigator(Kenkyū-buntansha) KINUGASA Takashi  University of Tsukuba, Graduate School of Comprehensive Human Sciences, Professor, 大学院人間総合科学研究科, 教授 (40110481)
OHNO Hideki  Kyorin University, Department of Preventive Medicine and Public Health, Professor, 医学部, 教授 (00133819)
KASTUMURA Toshihito  Tokyo Medical University, Department of Preventive Medicine and Public Health, Professor, 医学部, 教授 (80214352)
武政 徹  筑波大学, 体育科学系, 講師 (50236501)
Project Period (FY) 2003 – 2006
Project Status Completed (Fiscal Year 2006)
Budget Amount *help
¥50,830,000 (Direct Cost: ¥39,100,000、Indirect Cost: ¥11,730,000)
Fiscal Year 2006: ¥7,670,000 (Direct Cost: ¥5,900,000、Indirect Cost: ¥1,770,000)
Fiscal Year 2005: ¥24,310,000 (Direct Cost: ¥18,700,000、Indirect Cost: ¥5,610,000)
Fiscal Year 2004: ¥7,670,000 (Direct Cost: ¥5,900,000、Indirect Cost: ¥1,770,000)
Fiscal Year 2003: ¥11,180,000 (Direct Cost: ¥8,600,000、Indirect Cost: ¥2,580,000)
Keywordsskeletal muscle / calcineurin / fiber type change / PGC-1alpha / muscle oxygenation levels / near-infrared spectroscopy / isokinetic contraction / isometric contraction / PGC-1 α / アイソカイネティック / アイソメトリック / NFAT / MEF2 / レジスタンストレーニング / 成長ホルモン / コルチゾール / 高地トレーニング / ヘモグロビン / トレーニング / 筋線維タイプ / 筋代謝能 / ミオグロビン / 筋バイオプシー / mRNA / RT-PCR
Research Abstract

Skeletal muscle is highly adaptable and can change its structural and functional properties in response to physiological stimuli. Increased muscle activity due to a variety of conditions, such as resistance exercise and functional overload, induces skeletal muscle hypertrophy and muscle fiber-type transformation toward a slow profile. On the other hand, muscle inactivity, as can occur with bed rest, immobilization, and microgravity, is associated with muscle atrophy and fiber-type transformation toward a fast profile. During this project period, we have demonstrated some of the processes at the molecular level. Followings are some examples of analyses, but this space is too small to summarize all the research results, therefore, please refer to the references and paper version of the closing project report.
Calcineurin (CaN) signaling pathway has been implicated in the transcriptional regulation of slow muscle fiber genes and in muscle hypertrophy. To investigate the functional role of … More CaN as a regulator of muscle growth and/or muscle fiber type under conditions of recovery from inactivity, ICR mice were used for examining the effects of hindlimb suspension (HS) and reloading on skeletal muscle fiber size and muscle fiber type. Unexpectedly, we observed an increase in protein contents of CaN and its downstream effectors after HS, although the muscle fiber type transformed toward a fast profile and obvious muscle atrophy was induced.
It is generally accepted that endurance exercise increases the expression of peroxisome proliferator-activated receptor gamma coactivator-1alpha (PGC-1alpha), which governs the expression of oxidative metabolic enzymes. A previous report demonstrated that the regulation of mitochondrial protein expression in skeletal muscles in response to cold exposure depends on muscle fibre type. Since cold exposure and endurance exercise are both metabolic challenges that require adjustments in mitochondrial energy metabolism, we hypothesized that the exercise-induced increase in oxidative enzymes and PGC-1alpha expression is higher in fast-type than in slow-type muscle. From the results, endurance exercise induced increase in PGC-1alpha, but the degree of increase was muscle type-specific. Therefore, the increase in PGC-1alpha expression is not the only factor that promotes oxidative capacity as a result of endurance exercise
On the other hand, we analyzed the systemic distribution of slow muscle fibers in all rodent skeletal muscles by myosin ATPase staining and found that only seven hindlimb skeletal muscles were extremely rich in slow muscle fibers. Moreover, we analyzed transcription regulation of gene expression in human skeletal muscle in response to endurance training. Less

Report

(5 results)
  • 2006 Annual Research Report   Final Research Report Summary
  • 2005 Annual Research Report
  • 2004 Annual Research Report
  • 2003 Annual Research Report
  • Research Products

    (125 results)

All 2007 2006 2005 2004 2003 Other

All Journal Article (109 results) Book (9 results) Publications (7 results)

  • [Journal Article] Transcription regulation of gene expression in rat brown adipose tissue in response to unloading or 2G loading during growing period.2007

    • Author(s)
      Watanabe, S. et al.
    • Journal Title

      Acta Astronaut (in press)

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Disposition of protein-bound 3-nitrotyrosine in rat plasma analyzedby a novel protocol for HPLC-ECD.2007

    • Author(s)
      Hitomi, Y. et al.
    • Journal Title

      J. Biochem. (in press)

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Role (s) of gravitational loading on the transcription regulation of gene expression in rat brown adipose tissue during growing period.2007

    • Author(s)
      Ohira, Y. et al.
    • Journal Title

      J. Gravitat. (in press)

    • Related Report
      2006 Annual Research Report
  • [Journal Article] A report of Japan workshop n Antarctic medical research and medicine 2006.2007

    • Author(s)
      Ohno, G. et al.
    • Journal Title

      Antarctic Record (in press)

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Characterization of pollen dispersion in the neighborhood of Tokyo, Japan in the spring of 2005 and 2006.2007

    • Author(s)
      Ishibashi, Y. et al.
    • Journal Title

      Int. J. Environ. Res. Public Health (in press)

    • Related Report
      2006 Annual Research Report
  • [Journal Article] 花粉飛散における生体反応の特性と原因療法2007

    • Author(s)
      石橋義永.et al.
    • Journal Title

      環境と測定技術 (印刷中)

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Disturbance of microcirculation due to unhealthy lifestyle : Cause of type 2 diabetes.2006

    • Author(s)
      Matsumoto, Y. et al.
    • Journal Title

      Med. Hypotheses 66

      Pages: 550-553

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Annual Research Report 2006 Final Research Report Summary
  • [Journal Article] Calcineurin-mediated slow-type fiber expression and growth in reloading condition.2006

    • Author(s)
      Miyazaki, M. et al.
    • Journal Title

      Med. Sci. Sports Exerc 38

      Pages: 1065-1072

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Muscle type-specific response of PGC-1 α and oxidative enzymes during voluntary wheel running in mouse skeletal muscle.2006

    • Author(s)
      Ikeda, S. et al.
    • Journal Title

      Acta Physiol 188

      Pages: 217-223

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Muscle Oxygenation Heterogeneity in a Single Muscle at Rest and during Bicycle Exercise.2006

    • Author(s)
      Kime, R. et al.
    • Journal Title

      Jpn. J. Phys. Fitness Sports Med 55(Suppl)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Muscle oxygenation kinetics on isokinetic exercise-comparison with isometric exercise-.2006

    • Author(s)
      Mitsuoka, K. et al.
    • Journal Title

      Journal of Clinical Welfare 3(1)

      Pages: 40-45

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Effects of Physical Activity on Age-related Decline in Oxygen Delivery to Working Muscles.2006

    • Author(s)
      Ichimura, S. et al.
    • Journal Title

      Jpn. J. Phys. Fitness Sports Med 55(Suppl)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Age and Activity Status Affect Muscle Reoxygenaiton Time after Maximal Cycling Exercise.2006

    • Author(s)
      Ichimura, S. et al.
    • Journal Title

      Med. Sci. Sports Exer 38(7)

      Pages: 1277-1281

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Disturbance of microcirculation due to unhealthy lifestyle : Cause of type 2 diabetes.2006

    • Author(s)
      Matsumoto, Y., Ohno, H., Noguchi, I., Kikuchi, Y., Kurihara, T.
    • Journal Title

      Med.Hypotheses 66

      Pages: 550-553

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Calcineurin-mediated slow-type fiber expression and growth in reloading condition.2006

    • Author(s)
      Miyazaki, M., Hitomi, Y., Kizaki, T., Ohno, H., Katsunuma, T., Haga, S., Takemasa, T.
    • Journal Title

      Med.Sci.Sports Exerc. 38

      Pages: 1065-1072

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Muscle type-specific response of PGC-1 α and oxidative enzymes during voluntary wheel running in mouse skeletal muscle.2006

    • Author(s)
      Ikeda, S., Kawamoto, H., Kasaoka, K., Hitomi, Y., Kizaki, T., Sankai, Y., Ohno, H., Haga, S., Takemasa, T
    • Journal Title

      Acta Physiol. 188

      Pages: 217-223

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Muscle Oxygenation Heterogeneity in a Single Muscle at Rest and during Bicycle Exercise.2006

    • Author(s)
      Kime, R., Osada T, Shiroishi K, Ichimura S, Kurosawa Y.Homma T, Nakagawa N, Miyazaki J, Murase N, Katsumura T.
    • Journal Title

      Jpn.J.Phys.Fitness Sports Med. 55(Suppl)

    • NAID

      110004821436

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Muscle oxygenation kinetics on isokinetic exercise-comparison with isometric exercise・2006

    • Author(s)
      Mitsuoka, K., Kime, R., Osada, T., Murase, N., Katsumura, T.
    • Journal Title

      Journal of Clinical Welfare 3 (1)

      Pages: 40-45

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Effects of Physical Activity on Age-related Decline in Oxygen Delivery to Working Muscles.2006

    • Author(s)
      Ichimura, S., N.Murase, T.Osada, R.Kime, T.Homma, C.Ueda, T.Nagasawa, M.Motobe, T.Hamaoka, T.Katsumura.
    • Journal Title

      Jpn.J.Phys.Fitness Sports Med. 55(Suppl)

    • NAID

      110004821476

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Age and Activity Status Affect Muscle Reoxygenation Time after Maximal Cycling Exercise.2006

    • Author(s)
      Ichimura, S., N.Murase, T.Osada, R.Kime, T.Homma, C.Ueda, T.Nagasawa, M.Motobe, T.Hamaoka, T.Katsumura.
    • Journal Title

      Med.Sci.Sports Exer. 38 (7)

      Pages: 1277-1281

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] β-adrenergic receptor trafficking by exercise in rat adipocytes : roles of G-protein-coupled receptor kinase-2, β-arrestin-2, and the ubiquitin-proteasome pathway.2006

    • Author(s)
      Ogasawara, J. et al.
    • Journal Title

      FASEB J 20

      Pages: 350-352

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Calcineurin-mediated slow-type fiber expression and growth in reloading condition2006

    • Author(s)
      Miyazaki, M. et al.
    • Journal Title

      Med. Sci. Sports Exerc 38

      Pages: 1065-1072

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Muscle type-specific response of PGC-1 α and oxidative enzymes during voluntary wheel running in mouse skeletal muscle2006

    • Author(s)
      Ikeda, S. et al.
    • Journal Title

      Acta Physiol 188

      Pages: 217-223

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Muscle oxygenation kinetics on isokinetic exercise-comparison with isometric exercise-2006

    • Author(s)
      Mitsuoka, K. et al.
    • Journal Title

      Journal of Clinical Welfare 3(1)

      Pages: 40-45

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Age and Activity Status Affect Muscle Reoxygenaiton Time after Maximal Cycling Exercise2006

    • Author(s)
      Ichimura, S. et al.
    • Journal Title

      Med. Sci. Sports Exer 38(7)

      Pages: 1277-1281

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Fatal hyperthermia due to dental treatment.2006

    • Author(s)
      Noguchi, I. et al.
    • Journal Title

      Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod. 12

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Effects of acute exercise on lung antioxidant enzymes in young and old rats.2006

    • Author(s)
      Hatao, H. et al.
    • Journal Title

      Mech. Ageing Dev. 127

      Pages: 384-390

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Gliclazide protects 3T3L1 adipocytes against insulin resistance induced by hydrogen peroxide with restoration of GLUT4 translocation.2006

    • Author(s)
      Shimoyama, T. et al.
    • Journal Title

      Metabolism 55

      Pages: 722-730

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Effects of Bicycle Ergmeter Exercise and PGE1 Injection for Patients with Intermittent Claudication.2006

    • Author(s)
      Murase, N. et al.
    • Journal Title

      Jpn. J. Phys. Fitness Sports Med. 55(Suppl)

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Muscle Oxygenation Heterogeneity in a Single Muscle at Rest and during Bicycle Exercise.2006

    • Author(s)
      Kime, R. et al.
    • Journal Title

      Jpn. J. Phys. Fitness Sports Med. 55(Suppl)

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Effects of Physical Activity on Age-related Decline in Oxygen Delivery to Working Muscles.2006

    • Author(s)
      Ichimura, S. et al.
    • Journal Title

      Jpn. J. Phys. Fitness Sports Med. 55(Suppl)

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Change of Forearm Muscle Oxygen Consumption in Pediatrie Kidney ransplant Patients.2006

    • Author(s)
      Miyakawa S. et al.
    • Journal Title

      Jpn. j. Phys. Fitness Sports Med. 55(Suppl)

    • Related Report
      2006 Annual Research Report
  • [Journal Article] 酸素と運動の最近の知見.2006

    • Author(s)
      大野秀樹.et al.
    • Journal Title

      THE LUNG perspectives 14

      Pages: 71-75

    • Related Report
      2006 Annual Research Report
  • [Journal Article] 運動と活性酸素 : 人体におけるその代謝と疾病.2006

    • Author(s)
      大野秀樹.et al.
    • Journal Title

      臨床スポーツ医学 23

      Pages: 13-18

    • NAID

      10019248546

    • Related Report
      2006 Annual Research Report
  • [Journal Article] 注意すべき重金属汚染と健康被害.2006

    • Author(s)
      大野秀樹.et al.
    • Journal Title

      日本医事新報 4296

      Pages: 70-72

    • Related Report
      2006 Annual Research Report
  • [Journal Article] 近赤外分光法を用いた鍼灸刺激による筋血液量測定についての検討.2006

    • Author(s)
      大久保正樹.et al.
    • Journal Title

      脈管学 46 (1-2)

      Pages: 37-43

    • Related Report
      2006 Annual Research Report
  • [Journal Article] オーバートレーニング症候群の診断・判定に有用な指標.2006

    • Author(s)
      勝村 俊仁
    • Journal Title

      臨床スポーツ医学 23(8)

      Pages: 883-887

    • NAID

      10018362277

    • Related Report
      2006 Annual Research Report
  • [Journal Article] 等速性膝関節伸展屈曲運動のピークトルク低下率と運動初期脱酸素科率との関連.2006

    • Author(s)
      光岡かおり.et al.
    • Journal Title

      脈管学 46 (1-2)

      Pages: 31-36

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Calcineurin mediated slow-type fiber expression and growth in reloading condition.2006

    • Author(s)
      Mitsunori Miyazaki, et al.
    • Journal Title

      Med.Sci.Sports Physiol (印刷中)

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Seven skeletal muscles rich in slow muscle fibers may function to sustain neutral position in the rodent hindlimb.2005

    • Author(s)
      Hitomi, Y. et al.
    • Journal Title

      Comp. Biochem. Physiol. B Biochem. Mol. Biol 140

      Pages: 45-50

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Is angiotensin I-converting enzyme I/D polymorphism associated with endurance performance and/or high altitude adaptation?2005

    • Author(s)
      Ohno, H. et al.
    • Journal Title

      Adv. Exerc. Sports Physiol 11

      Pages: 41-54

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] We have two strategies to attain healthy ageing.2005

    • Author(s)
      Ohno, H. et al.
    • Journal Title

      Geriatr. Gerontol. Int 4

    • NAID

      10018027970

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Effects of intensity and duration of endurance exercise on skeletal muscle fiber type transition in mice.2005

    • Author(s)
      Miyazaki, M. et al.
    • Journal Title

      Adv. Exerc. Sports Physiol 11

      Pages: 15-20

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Changes in nitric oxide and inducible nitric oxide synthase following stretch-induced injury to the tibialis anterior muscle of rabbit.2005

    • Author(s)
      Sakurai, T. et al.
    • Journal Title

      Jpn. J. Physiol 55

      Pages: 101-107

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Effects of blackcurrant anthocyanin intake on peripheral muscle circulation during typing work in humans.2005

    • Author(s)
      Matsumuto, T. et al.
    • Journal Title

      Eur J Appl Physiol 94

      Pages: 289-300

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Reduced heterogeneity of muscle deoxygenation during heavy bicycle exercise.2005

    • Author(s)
      Kime, R. et al.
    • Journal Title

      Med Sci Sports Exer 37(3)

      Pages: 412-417

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Seven skeletal muscles rich in slow muscle fibers may function to sustain neutral position in the rodent hindlimb.2005

    • Author(s)
      Hitomi, Y., Kizaki, T., Watanabe, S., Matsumura, G, Fujioka, Y., Haga, S., Izawa, T., Taniguchi, N., Ohno, H.
    • Journal Title

      Comp.Biochem.Physiol.B Biochem.Mol.Biol. 140

      Pages: 45-50

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Is angiotensin I-converting enzyme I/D polymorphism associated with endurance performance and/or high altitude adaptation ?2005

    • Author(s)
      Ohno, H., Kizaki, T., Suzuki, K., Hitomi, Y., Nakano, N., Sakurai, T., Ogiwara, R., Sakurai, T., Izawa, T., Noguchi, I., Nagasawa, J., Ohnuki, Y., Nukita, M., Haga, S.
    • Journal Title

      Adv.Exerc.Sports Physiol. 11

      Pages: 41-54

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] We have two strategies to attain healthy ageing.2005

    • Author(s)
      Ohno, H., kizaki, T., Hitomi, Y, Watanabe, S., Ishibashi, Y., Izawa, T., Saitoh, D., Kinugasa, T., Haga, S.
    • Journal Title

      Geriatr.Gerontol.Int. 4

    • NAID

      10018027970

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Effects of intensity and duration of endurance exercise on skeletal muscle fiber type transition in mice.2005

    • Author(s)
      Miyazaki, M., Hitomi, Y., Kizaki, T., Ohno, H., Haga, S.
    • Journal Title

      Adv.Exerc.Sports Physiol. 11

      Pages: 15-20

    • NAID

      110002706153

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Changes in nitric oxide and inducible nitric oxide synthase following stretch-induced injury to the tibialis anterior muscle of rabbit.2005

    • Author(s)
      Sakurai, T., Hollander, J., Brickson, S.L., Ohno, H., Ji, L.L., Izawa, T., Best, T.M.
    • Journal Title

      Jpn.J.Physiol. 55

      Pages: 101-107

    • NAID

      10016627319

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Effects of blackcurrant anthocyanin intake on peripheral muscle circulation during typing work in humans.2005

    • Author(s)
      Matsumuto, T., Takenami, H., Iwasaki-Kurashige, K., Osada, T^*, Katsumura, T., Hamaoka T.
    • Journal Title

      Eur J Appl Physiol 94

      Pages: 289-300

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Reduced heterogeneity of muscle deoxygenation during heavy bicycle exercise.2005

    • Author(s)
      Kime, R., Im, J., Moser, D., Lin, Y., Nioka, S., Katsumura, T., Chance, B.
    • Journal Title

      Med Sci Sports Exer 37 (3)

      Pages: 412-417

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Effects of intensity and duration of endurance exercise on skeletal muscle fiber type transition in mice.2005

    • Author(s)
      Mitsunori Miyazaki, et al.
    • Journal Title

      Adv.Exerc.Sports Physiol. 11

      Pages: 15-20

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Effects of intensity and duration of endurance exercise on skeletal muscle fiber type transition in mice.2005

    • Author(s)
      Mitsunori Miyazaki
    • Journal Title

      Adv.Exerc.Sports Physiol. (印刷中)

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Simple method for the identification of oxidative fibers in skeletal muscle.2004

    • Author(s)
      Takemasa, T. et al.
    • Journal Title

      Eur. J. Appl. Physiol 91

      Pages: 357-359

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Effect of hyperventilation during resistance exercise on hormonal response in humans.2004

    • Author(s)
      Takemasa, T. et al.
    • Journal Title

      Adv. Exerc. Sports Physiol 10

      Pages: 55-61

    • NAID

      110002706016

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Contribution of the calcineurin signaling pathway to overload-induced skeletal muscle fiber-type transition.2004

    • Author(s)
      Miyazaki, M. et al.
    • Journal Title

      J. Physiol. Pharmacol 55

      Pages: 751-764

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Extracellular superoxide dismutase and lifestyle related diseases.2004

    • Author(s)
      Ohno, H. et al.
    • Journal Title

      Curr. Top. Pharmacol 1

      Pages: 1-15

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Down-regulation of β2-adrenergic receptor expression by exercise training increases IL-12 production by macrophages following LPS stimulation.2004

    • Author(s)
      Itoh, C.E.et al.
    • Journal Title

      Biochem. Biophys. Res. Commun 322

      Pages: 979-984

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Hematological responses in juveniles after training at moderate altitude.2004

    • Author(s)
      Ohno, H. et al.
    • Journal Title

      Adv. Exerc. Sports Physiol 10

      Pages: 31-35

    • NAID

      110002706012

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Quantitaive measurements of aerobic/anaerobic ATP production rate during submaximal isometric exercise.2004

    • Author(s)
      Kimura, N. et al.
    • Journal Title

      Adv. Exerc. Sports Physiol 10(1)

      Pages: 15-24

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Noninvasive monitoring of deterioration in skeletal muscle function with forearm cast immobilization and the prevention of deterioration.2004

    • Author(s)
      Motobe, M. et al.
    • Journal Title

      Dynamic Medicine 3(2)

      Pages: 2-2

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Simple method for the identification of oxidative fibers in skeletal muscle.2004

    • Author(s)
      Takemasa, T., Sugimoto, K., Miyazaki, M., Machida, M., Ikeda, S., Hitomi, Y., Kizaki, T., Ohno, H., Yamashita, K., Haga, S.
    • Journal Title

      Eur.J.Appl.Physiol. 91

      Pages: 357-359

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Effect of hyperventilation during resistance exercise on hormonal response in humans.2004

    • Author(s)
      Takemasa, T., Miyazaki, S., Nagata, S., Esaki, K., Hirokawa, M., Machida, M., Kosaka, Y., Hitomi, Y., Kizaki, T., Ohno, H., Haga, S.
    • Journal Title

      Adv.Exerc.Sports Physiol. 10

      Pages: 55-61

    • NAID

      110002706016

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Contribution of the calcineurin signaling pathway to overload-induced skeletal muscle fiber-type transition.2004

    • Author(s)
      Miyazaki, M., Hitomi, Y., Kizaki, T., Ohno, H., Haga, S., Takemasa, T.
    • Journal Title

      J.Physiol.Pharmacol. 55

      Pages: 751-764

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Extracellular superoxide dismutase and lifestyle related diseases.2004

    • Author(s)
      Ohno, H., Ookawara, T., Kizaki, T., Hitomi, Y., Oh-ishi, S., Saitoh, D., Kimoto, K., Itoh, C., Izawa, T., Haga, S., Suzuki, K., Radak, Z.
    • Journal Title

      Curr.Top.Pharmacol. 1

      Pages: 1-15

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Down-regulation of β 2-adrenergic receptor expression by exercise training increases IL-12 production by macrophages following LPS stimulation.2004

    • Author(s)
      Itoh, C.E., Kizaki, T., Hitomi, Y, Hanawa, T., Kamiya, S., Ookawara, T., Suzuki, K., Izawa, T., Saitoh, D., Haga, S., Ohno, H.
    • Journal Title

      Biochem.Biophys.Res.Commun. 322

      Pages: 979-984

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Hematological responses in juveniles after training at moderate altitude.2004

    • Author(s)
      Ohno, H., Kim, C.K., Kim, J.H., Jung, Y.S., Bae, S.Y., Toshinai, K., Miyazaki, H., Esaki, K., Takemasa, T., Kinugasa, T., kizaki, T., Hitomi, Y, Ookawara, T., Oh-ishi, S., Haga, S.
    • Journal Title

      Adv.Exerc.Sports Physiol. 10

      Pages: 31-35

    • NAID

      110002706012

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Quantitative measurements of aerobic/anaerobic ATP production rate during submaximal isometric exercise.2004

    • Author(s)
      Kimura, N., Hamaoka, T., Kurosawa, Y., Katsumura, T.
    • Journal Title

      Adv.Exerc.Sports Physiol 10(1)

      Pages: 15-24

    • NAID

      110002706010

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Noninvasive monitoring of deterioration in skeletal muscle function with forearm cast immobilization and the prevention of deterioration.2004

    • Author(s)
      Motobe, M., Murase, N., Osada, T., Homma, T., Ueda, C., Nagasawa, T., Kitahara, A., Ichimura, S., Kurosawa, Y., Katsumura, T., Hoshika, A., Hamaoka, T.
    • Journal Title

      Dynamic Medicine 3(2)

      Pages: 2-2

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Hematological responses in juveniles after training at moderate altitude.2004

    • Author(s)
      Hideki Ohno, et al.
    • Journal Title

      Adv.Exerc.Sports Physiol. 10

      Pages: 31-35

    • NAID

      110002706012

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Effect of Hyperventilation During Resistance Exercise on Hormonal Response in Humans.2004

    • Author(s)
      Tohru Takemasa
    • Journal Title

      Adv.Exert.Sports Physiol. 10

      Pages: 55-61

    • NAID

      110002706016

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Contribution of the calcineurin signaling pathway to overload- induced skeletal muscle fiber-type transition.2004

    • Author(s)
      Mitsunori Miyazaki
    • Journal Title

      J.Physiol.Pharmacol. 55

      Pages: 751-764

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Effect of moderate acute exercise on expression of mRNA involved in the calcineurin signaling pathway in human skeletal muscle.2003

    • Author(s)
      Hitomi, Y. et al.
    • Journal Title

      IUBMB Life 55

      Pages: 409-413

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Effects of endurance training on three superoxide dusmutase isoenzymes in human plasma.2003

    • Author(s)
      Ookawara, T. et al.
    • Journal Title

      Free Radic.Res 37

      Pages: 713-719

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Genetic variation in hypoxia-inducible factor 1α and its possible association with high altitude adaptation in Sherpas.2003

    • Author(s)
      Suzuki, K. et al.
    • Journal Title

      Med. Hypotheses 61

      Pages: 385-389

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Cardiac output and stroke volume at anaerobic threshold during walking exercise in healthy aged subjects.2003

    • Author(s)
      Haga, S. et al.
    • Journal Title

      Adv. Exerc. Sports Physiol 9

      Pages: 37-43

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Effect of eccentric exercise on neutrophil function in human plasma.2003

    • Author(s)
      Miyazaki, H. et al.
    • Journal Title

      Adv.Exerc.Sports Physiol 9

      Pages: 69-75

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Physical exercise and extracellular superoxide dismutase : antiatherogenic effects.2003

    • Author(s)
      Ohno, H. et al.
    • Journal Title

      Adv. Exerc. Sports Physiol 9

      Pages: 45-53

    • NAID

      110002706332

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Intermittent hypobaric hypoxia increases the ability of neutrophils to generate superoxide anion in humans.2003

    • Author(s)
      Hitomi, Y. et al.
    • Journal Title

      Clin. Exp. Pharmacol. Physiol 30

      Pages: 659-664

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Enhanced expression of neuronal nitric oxide synthase in islets of exercise-trained rats.2003

    • Author(s)
      Ueda, H. et al.
    • Journal Title

      Biochem.Biophys. Res. Commun 312

      Pages: 794-800

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Low oxygen pressure and oxidative stress : is it a paradox?2003

    • Author(s)
      Radak, Z., Ohno, H.
    • Journal Title

      Jpn. J. Mountain Med 23

      Pages: 9-14

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Significance of antioxidant supplementation during and after mountaineering.2003

    • Author(s)
      Ohno, H. et al.
    • Journal Title

      Jpn. J. Mountain Med 23

      Pages: 779-781

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Delayed reoxygenation after maximal isometric handgrip exercise in high oxidative capacity muscle.2003

    • Author(s)
      Kime, R. et al.
    • Journal Title

      Eur J Appl Physiol 89

      Pages: 34-41

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Creatine supplementation enhances anaerobic ATP synthesis during a single 10 sec maximal handgrip exercise.2003

    • Author(s)
      Kurosawa, Y. et al.
    • Journal Title

      Mol Cell Biochem 244

      Pages: 105-112

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] A practical indicator of muscle oxidative capacity determined by recovery of muscle O2 consumption using NIR spectroscopy.2003

    • Author(s)
      Nagasawa, T. et al.
    • Journal Title

      European Journal of Sports Science 3(2)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Deterioration of muscle function after 21-day forearm immobilization.2003

    • Author(s)
      Kitahara, A. et al.
    • Journal Title

      Med. Sci. Sports Exerc 35(10)

      Pages: 1697-1702

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Post-exercise hyperemia after ischemic and non-ischemic isometric handgrip exercise.2003

    • Author(s)
      Osada, T. et al.
    • Journal Title

      J. Physiol. Anthropol. Appl. Human Sci 22(6)

      Pages: 299-309

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Quantitative evaluation of oxygenation and metabolism in the human skeletal muscle.2003

    • Author(s)
      Hamaoka, T. et al.
    • Journal Title

      Opt Rev 10(5)

      Pages: 493-497

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Effect of moderate acute exercise on expression of mRNA involved in the calcineurin signaling pathway in human skeletal muscle.2003

    • Author(s)
      Hitomi, Y., Kizaki, T., Katsunuma, T., Mizuno, M., Itoh, C., Esaki, K., Fujioka, Y., Takemasa, T., Haga, S., Ohno, H.
    • Journal Title

      IUBMB Life 55

      Pages: 409-413

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Effects of endurance training on three superoxide dismutase isoenzymes in human plasma.2003

    • Author(s)
      Ookawara, T., Haga, S., Ha, S., Oh-ishi, S., Toshinai, K., Ji, L.L., Suzuki, K., Ohno, H.
    • Journal Title

      Free Radic.Res. 37

      Pages: 713-719

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Genetic variation in hypoxia-inducible factor 1 α and its possible association with high altitude adaptation in Sherpas.2003

    • Author(s)
      Suzuki, K., Kizaki, T., Hitomi, Y., Nukita, M., Kimoto, K., Miyazawa, N., Kobayashi, K., Ohnuki, Y., Ohno, H.
    • Journal Title

      Med. Hypotheses 61

      Pages: 385-389

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Cardiac output and stroke volume at anaerobic threshold during walking exercise in healthy aged subjects.2003

    • Author(s)
      Haga, S., Esaki, K., Toshinai, K., Kinugasa, T., Takemasa, T., Ueya, E., Hamaoka, T., Katsumura, T., Kizaki, T., Ohno, H.
    • Journal Title

      Adv. Exerc. Sports Physiol. 9

      Pages: 37-43

    • NAID

      110002706331

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Effect of eccentric exercise on neutrophil function in human plasma.2003

    • Author(s)
      Miyazaki, H., Haga, S., Suzuki, K., Toshinai, K., Esaki, K., Oh-ishi, S., Hitomi, Y., Kizaki, T., Ji, L.L., Ohno, H.
    • Journal Title

      Adv. Exerc.Sports Physiol. 9

      Pages: 69-75

    • NAID

      110002706335

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Physical exercise and extracellular superoxide dismutase : antiatherogenic effects.2003

    • Author(s)
      Ohno, H., Kizaki, T., Suzuki, K., Hitomi, Y., Watanabe, S., Ookawara, T., Suzuki, K., Haga, S., Saitoh, D., Radak, Z., Ji, L.L.
    • Journal Title

      Adv. Exerc.Sports Physiol. 9

      Pages: 69-75

    • NAID

      110002706332

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Intermittent hypobaric hypoxia increases the ability of neutrophils to generate superoxide anion in humans.2003

    • Author(s)
      Hitomi, Y, Miyamura, M., Mori, S., Suzuki, K., Kizaki, T., Itoh, C., Murakami, K., Haga, S., Ohno, H.
    • Journal Title

      Clin. Exp. Pharmacol. Physiol. 30

      Pages: 659-664

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Enhanced expression of neuronal nitric oxide synthase in islets of exercise-trained rats.2003

    • Author(s)
      Ueda, H., Urano, Y, Sakurai, T., Kizaki, T., Hitomi, Y., Ohno, H., Izawa, T.
    • Journal Title

      Biochem. Biophys. Res. Commun. 312

      Pages: 794-800

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Low oxygen pressure and oxidative stress : is it a paradox ?2003

    • Author(s)
      Radak, Z., Ohno, H.
    • Journal Title

      Jpn.J.Mountain Med. 23

      Pages: 9-14

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Significance of antioxidant supplementation during and after mountaineering.2003

    • Author(s)
      Ohno, H., Kizaki, T., Hitomi, Y., Watanabe, S., Kimoto, K., Itoh, C.E., Wako, N., Miyazawa, N., Ogiwara, R., Arai, T., Murakami, K., Suzuki, K., Oh-ish, S., Nagasawa, J., Watanabe, K., Ochi, T., Ochi, H., Radak, Z., Haga, S.
    • Journal Title

      Jpn.J.Mountain Med. 23

      Pages: 779-781

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Delayed reoxygenation after maximal isometric handgrip exercise in high oxidative capacity muscle.2003

    • Author(s)
      Kime, R., Hamaoka, T., Sako, T., Murakami, M., Homma, T., Katsumura, T., Chance, B.
    • Journal Title

      Eur J Appl Physiol 89

      Pages: 34-41

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Creatine supplementation enhances anaerobic ATP synthesis during a single 10 sec maximal handgrip exercise.2003

    • Author(s)
      Kurosawa, Y., Hamaoka, T., Katsumura, T., Kuwamori, M., Kimura, N., Sako, T., Chance, B.
    • Journal Title

      Mol Cell Biochem 244

      Pages: 105-112

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] A practical indicator of muscle oxidative capacity determined by recovery of muscle 02 consumption using NIR spectroscopy.2003

    • Author(s)
      Nagasawa, T., Hamaoka, T., Sako, T., Murakami, M., Kime, R., Homma, T., Ueda, C., Ichimura, S., Katsumura, T.
    • Journal Title

      European Journal of Sports Science 3(2)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Deterioration of muscle function after 21-day forearm immobilization.2003

    • Author(s)
      Kitahara, A., Hamaoka, T., Murase, N., Homma, T., Kurosawa, Y., Ueda, C., Nagasawa, T., Ichimura, S., Motobe, M., Yashiro, K., Nakano, S., Katsumura, T.
    • Journal Title

      Med.Sci.Sports Exerc 35(10)

      Pages: 1697-1702

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Post-exercise hyperemia after ischemic and non-ischemic isometric handgrip exercise.2003

    • Author(s)
      Osada, T., Katsumura, T., Murase, N., Sako, T., Higuchi, H., Kime, R., Hamaoka, T., Shimomitsu, T.
    • Journal Title

      J.Physiol.Anthropol. Appl. Human Sci 22(6)

      Pages: 299-309

    • NAID

      110002528198

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Quantitative evaluation of oxygenation and metabolism in the human skeletal muscle.2003

    • Author(s)
      Hamaoka, T., Osada, T., Murase, N., Sako, T., Higuchi, H., Kurosawa, Y, Miwa, M., Katsumura, T., Chance, B.
    • Journal Title

      Opt Rev, 10(5)

      Pages: 493-497

    • NAID

      10011757351

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Muscle oxygen consumption at onset of exercise by near infrared spectroscopy in humans.2003

    • Author(s)
      Hamaoka, T., Katsumura, T., Murase, N., Sako, T., Higuchi, H., Murakami, M., Esaki, K., Kime, R., Homma, T., Sugeta, A., Kurosawa, Y., Shimomitsu, T., Chance, B.
    • Journal Title

      Advances in Experimental Medicine and Biology, Oxygen (Transport to Tissue XXIV, Dunn, J.F., Swartz, H.M.) (Kluwer Academic/ Plenum Publishers) Vol. 530

      Pages: 475-483

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Muscle reoxygenation rate after isometric exercise at various intensities in relation to muscle oxidative capacity.2003

    • Author(s)
      Kime, R., Katsumura, T., Hamaoka, T., Osada, T., Sako, T., Murakami, M., Bae, S.Y., Toshinai, K., Haga, S., Shimomitsu, T.
    • Journal Title

      Advances in Experimental Medicine and Biology, Oxygen (Transport to Tissue XXIV, Dunn, J.F., Swartz, H.M.) (Kluwer Academic/ Plenum Publishers) Vol. 530

      Pages: 497-507

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] The effects of foods intake on muscle oxygen consumption.-Noninvasive measurement using NIRS.2003

    • Author(s)
      Ueda, C., Hamaoka, T., Murase, N., Osada, T., Sako, T., Murakami, M., Kime, R., Homma, T., Nagasawa, T., Kitahara, A., Ichimura, S., Moriguchi, T., Nakagawa, N., Katsumura, T.
    • Journal Title

      Advances in Experimental Medicine and Biology, Oxygen (Transport to Tissue XXV, M.S.Thorniley) (Kluwer Academic/ Plenum Publishers) Vol. 540

      Pages: 277-286

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Book] レーヴン/ジョンソン生物学(下巻)2007

    • Author(s)
      武政 徹(分担)
    • Publisher
      培風館
    • Related Report
      2006 Annual Research Report
  • [Book] 年軽10 歳這樣做-従現在開始的健康計晝、 台北縣板橋市2007

    • Author(s)
      芳賀脩光.et al.
    • Publisher
      悦智文化館
    • Related Report
      2006 Annual Research Report
  • [Book] 活性酸素と体力.,In 体力とはなにか2007

    • Author(s)
      大野秀樹, 木崎節子
    • Publisher
      ナップ
    • Related Report
      2006 Annual Research Report
  • [Book] 免疫と体力.In 体力とはなにか2007

    • Author(s)
      木崎節子, 大野秀樹
    • Publisher
      ナップ
    • Related Report
      2006 Annual Research Report
  • [Book] 第9回高所トレーニング国際シンポジウム 2005 in 飛騨 総集編2006

    • Author(s)
      大野秀樹
    • Total Pages
      4
    • Publisher
      NPO法人 高所トレーニング環境システム研究会編、
    • Related Report
      2006 Annual Research Report
  • [Book] 運動負荷試験と運動プログラム.In 運動処方の指針2006

    • Author(s)
      勝村俊仁
    • Total Pages
      33
    • Publisher
      南江堂
    • Related Report
      2006 Annual Research Report
  • [Book] Advances in Experimental Medicine and Biology Vol. 530 Oxygen Transport to Tissue XXIV2003

    • Author(s)
      Hamaoka, T. et al.
    • Total Pages
      9
    • Publisher
      Kluwer Academic/Plenum Publishers
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Book] Advances in Experimental Medicine and Biology Vol.530 Oxygen Transport to Tissue XXIV2003

    • Author(s)
      Kime, R. et al.
    • Total Pages
      11
    • Publisher
      Kluwer Academic/Plenum Publishers
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
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  • [Book] Advances in Experimental Medicine and Biology Vol. 540 Oxygen Transport to Tissue XXV2003

    • Author(s)
      Ueda, C. et al.
    • Total Pages
      10
    • Publisher
      Kluwer Academic/Plenum Publishers
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Publications] Hitomi, Y., et al.: "Effect of moderate acute exercise on expression of mRNA involved in ttthe calcineurin signaling pathway in human skeletal muscle"IUBMB Life. 55. 409-413 (2003)

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      2003 Annual Research Report
  • [Publications] Suzuki, K., et al.: "Genetic variation in hypoxia-inducible factor 1-alpha and its possible association with high altitude adaptation in Sherpas"Med.Hypotheses. 61. 385-389 (2003)

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      2003 Annual Research Report
  • [Publications] Haga, S., et al.: "Cardiac output and stroke volume at anaerobic threshold during walking exercise in healthy aged subjects"Adv.Exerc.Sports Physiol.. 9. 37-43 (2003)

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      2003 Annual Research Report
  • [Publications] Hitomi, Y., et al.: "Intermittent hypobaric hypoxia increases the ability of neutrophils to generate superoxide anion in humans"Clin.Exp.Pharmacol.Physiol.. 30. 659-664 (2003)

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  • [Publications] Ohno, H., et al.: "Extracellular superoxide dismutase and lifestyle related diseases (Review)"Curr.Top.Pharmacol.. 1. 1-15 (2004)

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      2003 Annual Research Report
  • [Publications] Takemasa, T., et al.: "Simple method for the identification of oxidative fibers in skeletal muscle"Eur.J.Appl.Physiol. 91. 357-359 (2004)

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  • [Publications] 芳賀脩光, 大野秀樹 編著: "トレーニング生理学"杏林書院. 375 (2003)

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Published: 2003-04-01   Modified: 2016-04-21  

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