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Investigation of gene and/or protein expression associated with recovery and/or regeneration of skeletal muscle from growth inhibition or damage

Research Project

Project/Area Number 15200049
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Research Field Sports science
Research InstitutionOsaka University

Principal Investigator

OHIRA Yoshinobu  Graduate School of Medicine, Osaka University, Professor, 医学系研究科, 教授 (50185378)

Co-Investigator(Kenkyū-buntansha) KAWANO Fuminori  Graduate School of Medicine, Osaka University, Assistant, 医学系研究科, 助手 (90346156)
OHMI Shinobu  Institute of Medical Science, University of Tokyo, Associate Professor, 医科学研究所, 助教授 (20160046)
OHIRA Yoshinobu  Graduate School of Medicine, Osaka University, Professor (50185378)
Project Period (FY) 2003 – 2006
Project Status Completed (Fiscal Year 2006)
Budget Amount *help
¥50,440,000 (Direct Cost: ¥38,800,000、Indirect Cost: ¥11,640,000)
Fiscal Year 2006: ¥8,190,000 (Direct Cost: ¥6,300,000、Indirect Cost: ¥1,890,000)
Fiscal Year 2005: ¥10,140,000 (Direct Cost: ¥7,800,000、Indirect Cost: ¥2,340,000)
Fiscal Year 2004: ¥11,570,000 (Direct Cost: ¥8,900,000、Indirect Cost: ¥2,670,000)
Fiscal Year 2003: ¥20,540,000 (Direct Cost: ¥15,800,000、Indirect Cost: ¥4,740,000)
KeywordsSkeletal muscle / Immune function / Proteomics / Regeneration / プロテオーム / 障害 / 老化 / 回復 / タンパク質 / 遺伝子 / 衛星細胞
Research Abstract

It has been well-known that the decreases of morphological and/or functional properties of skeletal muscles, caused by growth retardation, injury, long-term bedrest, spaceflight, or aging, inhibit the quality of life in daily life. Therefore, it is essential to develop the suitable methodology for the promotion of recovery and/or regeneration of muscles with inhibited properties or injury. Role(s) of interleukin-6 (IL-6), macrophage, satellite cell, and mechanical and/or metabolic stimuli in the regulation of muscular properties in response to damage or regeneration were studied. As the results, it was suggested that satellite cells play one of the key roles in the plasticity of muscle. The number and activity of satellite cells were decreased in muscle with atrophy or damage. On the contrary, data indicated that the recoveries of these parameters are essential for the regeneration of muscle. It was also suggested that the number and activity of satellite cells are regulated by mechanical stimuli, heat stress, IL-6, and macrophage. Further, it was indicated that the responses of gene and protein expression in rat soleus muscle to growth retardation, caused by gravitational unloading, and recovery in 1-G environment did not always coincide.

Report

(5 results)
  • 2006 Annual Research Report   Final Research Report Summary
  • 2005 Annual Research Report
  • 2004 Annual Research Report
  • 2003 Annual Research Report
  • Research Products

    (131 results)

All 2007 2006 2005 2004 2003 Other

All Journal Article (117 results) Book (13 results) Publications (1 results)

  • [Journal Article] Heat-stress facilitates the regeneration of injured skeletal muscle in rats.2007

    • Author(s)
      Kojima, A., K.Goto, S.Morioka, T.Naito, T.Akema, H.Fujiya, T.Sugiura, Y.Ohira, M.Beppu, H.Aoki, T.Yoshioka
    • Journal Title

      J. Orthopaed. Sci. 12

      Pages: 74-82

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Transcription regulation of gene expression in rat brown adipose tissue in response to unloading or 2G loading during growing period.2007

    • Author(s)
      Watanabe, S., Y.Hitomi, F.Kawano, Y.Ohira, T.Kizaki, N.Nakano, T.Sakurai, T.Izawa, K.Suzuki, M.Sudoh, R.R.Roy, H.Ohno
    • Journal Title

      Acta Astronautica 60

      Pages: 889-898

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Heat-stress facilitates the regeneration of injured skeletal muscle in rats.2007

    • Author(s)
      Kojima, A., K.Goto, S.Morioka, T.Naito, T.Akema, H.Fujiya, T.Sugiura, Y.Ohira, M.Beppu, H.Aoki, T.Yoshioka.
    • Journal Title

      J.Orthopaed.Sci. 12

      Pages: 74-82

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Annual Research Report 2006 Final Research Report Summary
  • [Journal Article] Transcription regulation of gene expression in rat brown adipose tissue in response to unloading or 2G loading during growing period.2007

    • Author(s)
      Watanabe, S., Y.Hitomi, F.Kawano, Y.Ohira, T.Kizaki, N.Nakano, T.Sakurai, T.Izawa, K.Suzuki, M.Sudoh, R.R.Roy, H.Ohno.
    • Journal Title

      Acta Astronautica 60

      Pages: 889-898

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Mechanical load-dependent regulation of satellite cell and fiber size in rat soleus muscle.2006

    • Author(s)
      Wang, X.D., F.Kawano, Y.Matsuoka, K.Fukunaga, M.Terada, M.Sudoh, A.Ishihara, Y.Ohira
    • Journal Title

      Am. J. Physiol. Cell Physiol. 290

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Irreversible morphplogical changes in leg bone following chronic gravitational unloading of growing rats.2006

    • Author(s)
      Ohira, Y., F.Kawano, X.D.Wang, M.Sudoh, Y.Iwashita, H.J.Majima, I.Nonaka
    • Journal Title

      Life Sci. 79

      Pages: 686-694

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Leucine-induced activation of translational initiation is partly regulated by the branched-chain α-keto acid dehydrogenase complex in C2C12 cells.2006

    • Author(s)
      Nakai, N., Y.Shimomura, T.Tamura, N.Tamura, K.Hamada, F.Kawano, Y.Ohira
    • Journal Title

      Biochem. Biophys. Res. Commun. 343

      Pages: 1244-1250

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] The role of neural and mechanical influences in maintaining normal fast and slow muscle properties.2006

    • Author(s)
      Ohira, Y., T.Yoshinaga, M.Ohara, F.Kawano, X.D.Wang, Y.Higo, M.Terada, Y.Matsuoka, R.R.Roy, V.R.Edgerton
    • Journal Title

      Cells Tissues Organs 182

      Pages: 129-142

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Comparison of cell body size and oxidative enzyme activity in motoneurons between the cervical and lumber segments in the rat spinal cord after spaceflight and recovery.2006

    • Author(s)
      Ishihara, A., J.Yamashiro, A.Matsumoto, A.Higashibata, N.Ishioka, T.Shimazu, Y.Ohira
    • Journal Title

      Neurochem. Res. 31

      Pages: 411-415

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Comparison of cell body size and oxidative enzyme activity in motoneurons between the cervical and lumbar segments in the spinal cord after spaceflight and recovery.2006

    • Author(s)
      Matsumoto, A., F.Kawano, A.Higashibata, N.Ishioka, T.Shimazu, Y.Ohira, A.Ishihara
    • Journal Title

      J. Gravit. Physiol. 13

      Pages: 11-12

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Effects of acute exposure to microgravity or hypergravity environment on motor control of arm in human.2006

    • Author(s)
      Terada, M., F.Kawano, X.D.Wang, Y.Matsuoka, T.Ochiai, H.Inada, Y.Ohira
    • Journal Title

      J. Gravit. Physiol. 13

      Pages: 33-34

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Role of macrophage function in regeneration of soleus muscle fibers in op/op mice.2006

    • Author(s)
      Wang, X.D., F.Kawano, Y.Matsuoka, M.Terada, H.Yamamoto, T.Ito, K.Goto, Y.B.Lan, Y.Ohira
    • Journal Title

      J. Gravit. Physiol. 13

      Pages: 77-78

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Responses of adductor longus muscle to hindlimb suspension in Wistar Hannover rats.2006

    • Author(s)
      Ohira, T., S.Morikuni, X.D.Wang, M.Terada, F.Kawano, Y.Matsuoka, Y.Higo, Y.B.Lan, T.Seki, Y.Ohira
    • Journal Title

      J. Gravit. Physiol. 13

      Pages: 79-80

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Role(s) of macrophage in the plasticity of plantaris muscle fibers in op/op mice.2006

    • Author(s)
      Morikuni, S., T.Ohira, X.D.Wang, M.Terada, F.Kawano, Y.Matsuoka, Y.B.Lan, H.Yamamoto, T.Ito, K.Goto, T.Seki, Y.Ohira
    • Journal Title

      J. Gravit. Physiol. 13

      Pages: 81-82

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Blockade of inerleukin-6 signaling pathway promotes muscle cell differentiation.2006

    • Author(s)
      Matsuoka, Y., F.Kawano, X.D.Wang, M.Terada, Y.Higo, Y.B.Lan, A.Ogura, N.Nishimoto, Y.Adachi, Y.Ohira
    • Journal Title

      J. Gravit. Physiol. 13

      Pages: 83-84

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Mechanical stress-dependent transformation of nucleoli in myonuclei of rat soleus muscle fibers.2006

    • Author(s)
      Kawano, F., Y.Matsuoka, Y.Oke, Y.Higo, M.Terada, X.D.Wang, Y.B.Lan, N.Nakai, Y.Ohira
    • Journal Title

      J. Gravit. Physiol. 13

      Pages: 85-86

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Effects of tenotomy and/or denervation on the characteristics of plantaris muscle fibers of mdx mice.2006

    • Author(s)
      Higo, Y., M.Terada, S.Umemoto, N.Kawabe, F.Kawano, Y.Ohira
    • Journal Title

      J. Gravit. Physiol. 13

      Pages: 87-88

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Change of bone mineral and morphology in growing rat leg bone after hindlimb unloading.2006

    • Author(s)
      Majima, H.J., Y.Iwashita, A.Higashibata, N.Ishioka, Y.Ohira
    • Journal Title

      J. Gravit. Physiol. 13

      Pages: 91-92

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Role(s) of gravitational loading on the transcription regulation of gene expression in rat brown adipose tissue during growing period.2006

    • Author(s)
      Ohira, Y., S.Watanabe, Y.Hitomi, F.Kawano, T.Kizaki, N.Nakano, T.Sakurai, T.Izawa, K.Suzuki, M.Sudoh, R.R.Roy, H.Ohno
    • Journal Title

      J. Gravit. Physiol. 13

      Pages: 151-152

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Mechanical load-dependent regulation of satellite cell and fiber size in rat soleus muscle.2006

    • Author(s)
      Wang, X.D., F.Kawano, Y.Matsuoka, K.Fukunaga, M.Terada, M.Sudoh, A.Ishihara, Y.Ohira.
    • Journal Title

      Am.J.Physiol.Cell Physiol. 290

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Irreversible morphplogical changes in leg bone following chronic gravitational unloading of growing rats.2006

    • Author(s)
      Ohira, Y., F.Kawano, X.D.Wang, M.Sudoh, Y.Iwashita, H.J.Majima, I.Nonaka.
    • Journal Title

      Life Sci. 79

      Pages: 686-694

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Leucine-induced activation of translational initiation is partly regulated by the branched-chain α-keto acid dehydrogenase complex in C2C12 cells.2006

    • Author(s)
      Nakai, N., Y.Shimomura, T.Tamura, N.Tamura, K.Hamada, F.Kawano, Y.Ohira.
    • Journal Title

      Biochem.Biophys.Res.Commun. 343

      Pages: 1244-1250

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] The role of neural and mechanical influences in maintaining normal fast and slow muscle properties.2006

    • Author(s)
      Ohira, Y., T.Yoshinaga, M.Ohara, F.Kawano, X.D.Wang, Y.Higo, M.Terada, Y.Matsuoka, R.R.Roy, Y.R.Edgerton.
    • Journal Title

      Cells Tissues Organs 182

      Pages: 129-142

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Comparison of cell body size and oxidative enzyme activity in motoneurons between the cervical and lumber segments in the rat spinal cord after spaceflight and recovery.2006

    • Author(s)
      Ishihara, A., J.Yamashiro, A.Matsumoto, A.Higashibata, N.Ishioka, T.Shimazu, Y.Ohira.
    • Journal Title

      Neurochem.Res 31

      Pages: 411-415

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Comparison of cell body size and oxidative enzyme activity in motoneurons between the cervical and lumbar segments in the spinal cord after spaceflight and recovery.2006

    • Author(s)
      Matsumoto, A., F.Kawano, A.Higashibata, N.Ishioka, T.Shimazu, Y.Ohira, A.Ishihara.
    • Journal Title

      J.Gravit.Physiol. 13

      Pages: 11-12

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Effects of acute exposure to microgravity or hypergravity environment on motor control of arm in human.2006

    • Author(s)
      Terada, M., F.Kawano, X.D.Wang, Y.Matsuoka, T.Ochiai, H.Inada, Y.Ohira.
    • Journal Title

      J.Gravit.Physiol. 13

      Pages: 33-34

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Role of macrophage function in regeneration of soleus muscle fibers in op/op mice.2006

    • Author(s)
      Wang, X.D., F.Kawano, Y.Matsuoka, M.Terada, H.Yamamoto, T.Ito, K.Goto, Y.B.Lan, Y.Ohira.
    • Journal Title

      J.Gravit.Physiol. 13

      Pages: 77-78

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Annual Research Report 2006 Final Research Report Summary
  • [Journal Article] Responses of adductor longus muscle to hindlimb suspension in Wistar Hannover rats.2006

    • Author(s)
      Ohira, T, S.Morikuni, X.D.Wang, M.Terada, F.Kawano, Y.Matsuoka, Y.Higo, Y.B.Lan, T.Seki, Y.Ohira.
    • Journal Title

      J.Gravit.Physiol. 13

      Pages: 79-80

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Role(s) of macrophage in the plasticity of plantaris muscle fibers in op/op mice.2006

    • Author(s)
      Morikuni, S., T.Ohira, X.D.Wang, M.Terada, F.Kawano, Y.Matsuoka, Y.B.Lan, H.Yamamoto, T.Ito, K.Goto, T.Seki, Y.Ohira.
    • Journal Title

      J.Gravit.Physiol. 13

      Pages: 81-82

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Blockade of inerleukin-6 signaling pathway promotes muscle cell differentiation.2006

    • Author(s)
      Matsuoka, Y., F.Kawano, X.D.Wang, M.Terada, Y.Higo, Y.B.Lan, A.Ogura, N.Nishimoto, Y.Adachi, Y.Ohira.
    • Journal Title

      J.Gravit.Physiol. 13

      Pages: 83-84

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Mechanical stress-dependent transformation of nucleoli in myonuclei of rat soleus muscle fibers.2006

    • Author(s)
      Kawano, F., Y.Matsuoka, Y.Oke, Y.Higo, M.Terada, X.D.Wang, Y.B.Lan, N.Nakai, Y.Ohira.
    • Journal Title

      J.Gravit.Physiol. 13

      Pages: 85-86

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Effects of tenotomy and/or denervation on the characteristics of plantaris muscle fibers of mdx mice.2006

    • Author(s)
      Higo, Y., M.Terada, S.Umemoto, N.Kawabe, F.Kawano, Y.Ohira.
    • Journal Title

      J.Gravit.Physiol. 13

      Pages: 87-88

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Annual Research Report 2006 Final Research Report Summary
  • [Journal Article] Change of bone mineral and morphology in growing rat leg bone after hindlimb unloading.2006

    • Author(s)
      Majima, H.J., Y.Iwashita, A.Higashibata, N.Ishioka, Y.Ohira.
    • Journal Title

      J.Gravit.Physiol. 13

      Pages: 91-92

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Annual Research Report 2006 Final Research Report Summary
  • [Journal Article] Role(s) of gravitational loading on the transcription regulation of gene expression in rat brown adipose tissue during growing period.2006

    • Author(s)
      Ohira, Y., S.Watanabe, Y.Hitomi, F.Kawano, T.Kizaki, N.Nakano, T.Sakurai, T.Izawa, K.Suzuki, M.Sudoh, R.R.Roy, H.Ohno.
    • Journal Title

      J.Gravit.Physiol. 13

      Pages: 151-152

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Mechanical load-dependent regulation of satellite cell and fiber size in rat soleus muscle.2006

    • Author(s)
      Wang, X.D., F.Kawano, Y.Matsuoka, K.Fukunaga, M.Terada, M.Sudoh, A., Ishihara, Y.Ohira.
    • Journal Title

      Am.J.Physiol.Cell Physiol. 290

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Irreversible morphological changes in leg bone following chronic gravitational unloading of growing rats.2006

    • Author(s)
      Ohira, Y., F.Kawano, X.D.Wang, M.Sudoh, Y.Iwashita, H.J.Majima, I.Nonaka.
    • Journal Title

      Life Sci. 79

      Pages: 686-694

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Leucine-induced activation of translation initiation is partly regulated by the branched-chain α-keto acid dehydrogenase complex in C2C12 cells.2006

    • Author(s)
      Nakai, N., Y.Shimomura, T.Tamura, N.Tamura, K.Hamada, F.Kawano, Y.Ohira.
    • Journal Title

      Biochem.Biophys.Res.Commun. 343

      Pages: 1244-1250

    • Related Report
      2006 Annual Research Report
  • [Journal Article] The role of neural and mechanical influences in maintaining normal fast and slow muscle properties.2006

    • Author(s)
      Ohira, Y., T.Yoshinaga, M.Ohara F.Kawano, X.D.Wang, Y.Higo, M.Terada, Y.Matsuoka, R.R.Roy, V.R.Edgerton.
    • Journal Title

      Cells Tissues Organs 182

      Pages: 129-142

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Comparison of cell body size and oxidative enzyme activity in motoneurons between the cervical and lumber segments in the rat spinal cord after spaceflight and recovery.2006

    • Author(s)
      Ishihara, A., J.Yamashiro, A.Matsumoto, A.Higashibata, N.Ishioka, T.shimazu, Y.Ohira.
    • Journal Title

      Neurochem.Res. 31

      Pages: 411-415

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Comparison of cell body size and oxidative enzyme activity in motoneurons between the cervical and lumber segments in the spinal cord after spaceflight and recovery.2006

    • Author(s)
      Matsumoto, A., F.Kawano, A.Higashibata, N.Ishioka, T.Shimazu, Y.Ohira, A.Ishihara.
    • Journal Title

      J.Gravit.Physiol. 13

      Pages: 11-12

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Effects of acute exposure to microgravity or hypergravity environment on motor control of arm in human.2006

    • Author(s)
      Terada, M., F.kawano, X.D.Wang, Y.Matsuoka, T.Ochiai, H.Inada, Y.Ohira.
    • Journal Title

      J.Gravit.Physiol. 13

      Pages: 33-34

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Responses of adductor longus muscle to hindlimb suspension in Wistar Hannover rats.2006

    • Author(s)
      Ohira, T., S.Morikuni, X.D.Wang, M.Terada, F.Kawano, Y.Matsuoka, Y.Higo, Y.B.Lan, T.Seki, Y.Ohira.
    • Journal Title

      J.Gravit.Physiol. 13

      Pages: 79-80

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Role(s) of macrophage in the plasticity of plantaris muscle fibers in op/op mice.2006

    • Author(s)
      Morikuni, S., T.Ohira, X.D.Wang, M.Terada, F.Kawano, Y.Matsuoka, Y.B.Lan, H.Yamamoto, T.Ito, T.Seki, Y.Ohira.
    • Journal Title

      J.Gravit.Physiol. 13

      Pages: 81-82

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Blockade of interleukin-6 signaling pathway promotes muscle cell differentiation.2006

    • Author(s)
      Matsuoka, Y., F.Kawano, X.D.Wang, M.Terada, Y.Higo, Y.B.Lan, A.Ogura, N.Nishimoto, Y.Adachi, Y.Ohira.
    • Journal Title

      J.Gravit.Physiol. 13

      Pages: 83-84

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Mechanical stress-dependent transformation of nucleoli in myonuclei of rat soleus muscle fibers.2006

    • Author(s)
      Kawano, F., Y.Matsuoka, Y.Oke, Y.Higo, M.Terada, X.D.Wang, Y.B.Lan, N.Nakai, Y.Ohira.
    • Journal Title

      J.Gravit.Physiol 13

      Pages: 85-86

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Role(s) of gravitational loading on the transcription regulation of gene expression in rat brown adipose tissue during growing period.2006

    • Author(s)
      Ohira, Y., S.Watanabe, Y.Hitomi, F.Kawano, T.Kizaki, N.Nakano, T.Sakurai, T.Izawa, K.Suzuki, M.Sudoh, R.R.Roy.
    • Journal Title

      J.Gravit.Physiol. 13

      Pages: 151-152

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Hyperbaric exposure with high oxygen concentration enhances oxidative capacity of neuromuscular units.2005

    • Author(s)
      Ishihara, A., F.Kawano, T.Okiura, F.Morimatsu, Y.Ohira
    • Journal Title

      Neurosci. Res. 52

      Pages: 146-152

    • NAID

      10016476471

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Calcineurin and heat shock protein 72 in functionally overloaded rat plantaris muscle.2005

    • Author(s)
      Oishi, Y., T.Ogata, Y.Ohira, K.Taniguchi, R.R.Roy
    • Journal Title

      Biochem. Biophys. Res. Commun. 330

      Pages: 706-713

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Possible role of calcineurin in heating-related increase of rat muscle mass.2005

    • Author(s)
      Kobayashi, T., K.Goto, A.Kojima, T.Akema, K.Uehara, H.Aoki, T.Sugiura, Y.Ohira, T.Yoshioka
    • Journal Title

      Biochem. Biophys. Res. Commun. 331

      Pages: 1301-1309

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Effects of cold-water immersion on VEGF mRNA and protein expression in heart and skeletal muscles of rats.2005

    • Author(s)
      Kim, J.C., H.K.Yi, P.H.Hwang, J.S.Yoon, H.J.Kim, F.Kawano, Y.Ohira, C.K.Kim
    • Journal Title

      Acta Physiol. Scand. 183

      Pages: 389-397

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Heat stress as a countermeasure for prevention of muscle atrophy in microgravity environment.2005

    • Author(s)
      Goto, K., A.Kojima, T.Kobayashi, K.Uehara, S.Morioka, T.Naito, T.Akema, T.Sugiura, Y.Ohira, T.Yoshioka
    • Journal Title

      Jpn. J. Aerospace Environ. Med. 42

      Pages: 51-59

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Different responses in soleus muscle fibers of Wistar and Wistar Hannover rats to hindlimb unloading.2005

    • Author(s)
      Wang, X.D., F.Kawano, M.Terada, Y.Matsuoka, Y.Shinoda, A.Ishihara, Y.Ohira
    • Journal Title

      J. Gravit. Physiol. 12

      Pages: 131-132

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Role of afferent input and mechanical load for size regulation of rat soleus muscle.2005

    • Author(s)
      Kawano, F., Y.Matsuoka, Y.Oke, Y.Higo, M.Terada, S.Umemoto, N.Kawabe, X.D.Wang, Y.Shinoda, Y.B.Lan, H.Fukuda, S.Ohmi, Y.Ohira
    • Journal Title

      J. Gravit. Physiol. 12

      Pages: 133-134

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Mechanical and/or neural activity-dependent regulation of soleus muscle fibers of mdx mice.2005

    • Author(s)
      Terada, M., F.Kawano, Y.B.Lan, Y.Matsuoka, X.D.Wang, Y.Ohira
    • Journal Title

      J. Gravit. Physiol. 12

      Pages: 135-136

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] How does the nucleolar number involve in muscle fiber atrophy? Response to β-guanidinopropionic acid supplementation.2005

    • Author(s)
      Matsuoka, Y., F.Kawano, Y.Oke, Y.Higo, S.Umemoto, N.Kawabe, X.D.Wang, M.Terada, Y.Shinoda, Y.B.Lan, A.Ishihara, Y.Ohira
    • Journal Title

      J. Gravit. Physiol. 12

      Pages: 147-148

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Hyperbaric exposure with high oxygen concentration enhances oxidative capacity of neuromuscular units.2005

    • Author(s)
      Ishihara, A., F.Kawano, T.Okiura, F.Morimatsu, Y.Ohira.
    • Journal Title

      Neurosci.Res. 52

      Pages: 146-152

    • NAID

      10016476471

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Calcineurin and heat shock protein 72 in functionally overloaded rat plantaris muscle.2005

    • Author(s)
      Oishi, Y., T.Ogata, Y.Ohira, K.Taniguchi, R.R.Roy.
    • Journal Title

      Biochem.Biophys.Res.Commun. 330

      Pages: 706-713

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Possible role of calcineurin in heating-related increase of rat muscle mass.2005

    • Author(s)
      Kobayashi, T., K.Goto, A.Kojima, T.Akema, K.Uehara, H.Aoki, T.Sugiura, Y.Ohira, T.Yoshioka.
    • Journal Title

      Biochem.Biophys.Res.Commun. 331

      Pages: 1301-1309

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Effects of cold-water immersion on VEGF mRNA and protein expression in heart and skeletal muscles of rats.2005

    • Author(s)
      Kim, J.C., H.K.Yi, P.H.Hwang, J.S.Yoon, H.J.Kim, F.Kawano, Y.Ohira, C.K.Kim.
    • Journal Title

      Acta Physiol.Scand 183

      Pages: 389-397

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Heat stress as a countermeasure for prevention of muscle atrophy in microgravity environment.2005

    • Author(s)
      Goto, K., A.Kojima, T.Kobayashi, K.Uehara, S.Morioka, T.Naito, T.Akema, T.Sugiura, Y.Ohira, T.Yoshioka.
    • Journal Title

      Jpn.J.Aerospace Environ.Med. 42

      Pages: 51-59

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Different responses in soleus muscle fibers of Wistar and Wistar Hannover rats to hindlimb unloading.2005

    • Author(s)
      Wang, X.D., F.Kawano, M.Terada, Y.Matsuoka, Y.Shinoda, A.Ishihara, Y.Ohira.
    • Journal Title

      J.Gravit.Physiol. 12

      Pages: 131-132

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Role of afferent input and mechanical load for size regulation of rat soleus muscle.2005

    • Author(s)
      Kawano, F., Y.Matsuoka, Y.Oke, Y.Higo, M.Terada, S.Umemoto, N.Kawabe, X.D.Wang, Y.Shinoda, Y.B.Lan, H.Fukuda, S.Ohmi, Y.Ohira.
    • Journal Title

      J.Gravit.Physiol. 12

      Pages: 133-134

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Mechanical and/or neural activity-dependent regulation of soleus muscle fibers of mdx mice.2005

    • Author(s)
      Terada, M., F.Kawano, Y.B.Lan, Y.Matsuoka, X.D.Wang, Y.Ohira.
    • Journal Title

      J.Gravit.Physiol. 12

      Pages: 135-136

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] How does the nucleolar number involve in muscle fiber atrophy? Response toβ-guanidinopropionic acid supplementation.2005

    • Author(s)
      Matsuoka, Y., F.Kawano, Y.Oke, Y.Higo, S.Umemoto, N.Kawabe, X.D.Wang, M.Terada, Y.Shinoda, Y.B.Lan, A.Ishihara, Y.Ohira.
    • Journal Title

      J.Gravit.Physiol. 12

      Pages: 147-148

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Possible role of calcineurin in heating-related increase of rat muscle mass.2005

    • Author(s)
      Kobayashi T., K.Goto, A.Kojima, T.Akema, K.Uehara, H.Aoki, T.Sugiura, Y.Ohira, T.Yoshioka
    • Journal Title

      Biocnem.Biophys.Res.Commun. 331

      Pages: 1301-1309

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Effects of cold-water immersion on VEGF mRNA and protein expression in heart and skeletal muscles of rats.2005

    • Author(s)
      Kim, J.C., HK.Yi, P.H.Hwang, J.S., Yoon, H.J.Kim, F.Kawano, Y.Ohira, C.K.Kim.
    • Journal Title

      Acta Physiol.Scand. 183

      Pages: 389-397

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Heat stress as a countermeasure for prevention of muscle atrophy in microgravity environment.2005

    • Author(s)
      Goto, K., A.Kojima, T.Kobayashi K.Uehara, S.Morioka, T., Naito, T.Akema T.Sugiura, Y.Ohira, T.Yoshioka.
    • Journal Title

      Jpn.J.Aerospace Environ.Med. 42

      Pages: 51-59

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Calcineurin and heat shock protein 72 in functionally overloaded rat plantaris muscle2005

    • Author(s)
      Oishi Y, T Ogata, Y Ohira, K Taniguchi, RR Roy
    • Journal Title

      Biochem Biophys Res Commun (In press)

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Effects of cold-water immersion on VEGF mRNA and protein expression in heart and skeletal muscles of rats2005

    • Author(s)
      Kim JC, HK Lee, PH Hwang, JS Yoon, HJ Kim, F Kawano, Y Ohira, CK Kim
    • Journal Title

      Acta Physiol Scand (In press)

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Tension- and afferent-input-associated responses of neuromuscular system of rats to hindlimb unloading and/or tenotomy.2004

    • Author(s)
      Kawano, F., A.Ishihara, J.L.Stevens, X.D.Wang, S.Ohshima, M.Horisaka, Y.Maeda, I.Nonaka, Y.Ohira
    • Journal Title

      Am. J. Physiol. Regul. Integr. Comp. Physiol. 287

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Hindlimb suspension inhibits air-righting due to altered recruitment of neck and back muscles in rats.2004

    • Author(s)
      Kawano, F., X.D.Wang, Y.B.Lan, H.Yonemitsu, A.Ishihara, M.Igarashi, Y.Ohira
    • Journal Title

      Jpn. J. Physiol. 54

      Pages: 229-242

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Heat-stress enhances proliferative potensial in rat soleus muscle.2004

    • Author(s)
      Uehara, K., K.Goto, T.Kobayashi, A.Kojima, T.Akema, T.Sugiura, S.Yamada, Y.Ohira, T.Yoshioka, H.Aoki
    • Journal Title

      Jpn. J. Physiol. 54

      Pages: 263-271

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Heat stress facilitates the recovery of atrophied soleus muscle in rat.2004

    • Author(s)
      Goto, K., M.Honda, T.Kobayashi, K.Uehara, A.Kojima, T.Akema, T.Sugiura, S.Yamada, Y.Ohira, T.Yoshioka
    • Journal Title

      Jpn. J. Physiol. 54

      Pages: 285-293

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Effects of running exercise during recovery from hindlimb unloading on soleus muscle fibers and their spinal motoneurons in rats.2004

    • Author(s)
      Ishihara, A., F.Kawano, N.Ishioka, H.Oishi, A.Higashibata, T.Shimazu, Y.Ohira
    • Journal Title

      Neurosci. Res. 48

      Pages: 119-127

    • NAID

      10014232881

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Effects of 20-week intermittent cold-water-immersion on phenotype and myonuclei in single fibers of rat hindlimb muscles.2004

    • Author(s)
      Lee, J.H., E.Y.Han, M.S.Kang, F.Kawano, H.J.Kim, Y.Ohira, C.K.Kim
    • Journal Title

      Jpn. J. Physiol. 54

      Pages: 331-337

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Role of gravity in mammalian development : effects of hypergravity and/or microgravity on the development of skeletal muscles.2004

    • Author(s)
      Ohira, Y., F.Kawano, K.Goto, X.D.Wang, Y.Takeno, A.Ishihara
    • Journal Title

      Biol. Sci. Space 18

      Pages: 124-125

    • NAID

      10014084701

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Load-dependent regulation of neuromuscular system.2004

    • Author(s)
      Ohira, Y., F.Kawano, A.Ishihara
    • Journal Title

      J. Gravit. Physiol. 11

      Pages: 127-128

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Tension-and afferent-input-associated responses of neuromuscular system of rats to hindlimb unloading and/or tenotomy.2004

    • Author(s)
      Kawano, F., A.Ishihara, J.L.Stevens, X.D.Wang, S.Ohshima, M.Horisaka, Y.Maeda, I.Nonaka, Y.Ohira.
    • Journal Title

      Am.J.Physiol.Regul.Integr.Comp.Physiol. 287

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Hindlimb suspension inhibits air-righting due to altered recruitment of neck and back muscles in rats.2004

    • Author(s)
      Kawano, F., X.D.Wang, Y.B.Lan, H.Yonemitsu, A.Ishihara, M.Igarashi, Y.Ohira.
    • Journal Title

      Jpn.J.Physiol. 54

      Pages: 229-242

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Heat-stress enhances proliferative potensial in rat soleus muscle.2004

    • Author(s)
      Uehara, K., K.Goto, T.Kobayashi, A.Kojima, T.Akema, T.Sugiura, S.Yamada, Y.Ohira, T.Yoshioka, H.Aoki.
    • Journal Title

      Jpn.J.Physiol. 54

      Pages: 263-271

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Heat stress facilitates the recovery of atrophied soleus muscle in rat.2004

    • Author(s)
      Goto, K., M.Honda, T.Kobayashi, K.Uehara, A.Kojima, T.Akema, T.Sugiura, S.Yamada, Y.Ohira, T.Yoshioka.
    • Journal Title

      Jpn.J.Physiol. 54

      Pages: 285-293

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Effects of running exercise during recovery from hindlimb unloading on soleus muscle fibers and their spinal motoneurons in rats.2004

    • Author(s)
      Ishihara, A., F.Kawano, N.Ishioka, H.Oishi, A.Higashibata, T.Shimazu, Y.Ohira.
    • Journal Title

      Neurosci.Res. 48

      Pages: 119-127

    • NAID

      10014232881

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Effects of 20-week intermittent cold-water-immersion on phenotype and myonuclei in single fibers of rat hindlimb muscles.2004

    • Author(s)
      Lee, J.H., E.Y.Han, M.S.Kang, F.Kawano, H.J.Kim, Y.Ohira, C.K.Kim.
    • Journal Title

      Jpn.J.Physiol. 54

      Pages: 331-337

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Role of gravity in mammalian development : effects of hypergravity and/or microgravity on the development of skeletal muscles.2004

    • Author(s)
      Ohira, Y., F.Kawano, K.Goto, X.D.Wang, Y.Takeno, A.Ishihara.
    • Journal Title

      Biol. Sci. Space 18

      Pages: 124-125

    • NAID

      10014084701

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Load-dependent regulation of neuromuscular system.2004

    • Author(s)
      Ohira, Y., F.Kawano, A.Ishihara.
    • Journal Title

      J.Gravit.Physiol. 11

      Pages: 127-128

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Heat-stress enhances proliferative potential in rat soleus muscle2004

    • Author(s)
      Uehara K, K Goto, T Kobayashi, A Kojima, T Akema, T Sugiura, S Yamada, Y Ohira, T Yoshioka, H Aoki
    • Journal Title

      Jpn J Physiol 54

      Pages: 263-271

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Effects of 20-week intermittent cold-water-immersion on phenotype and myonuclei in single fibers of rat hindlimb muscles2004

    • Author(s)
      Lee JH, EY Han, MS Kang, F Kawano, HJ Kim, Y Ohira, C.K. Kim
    • Journal Title

      Jpn J Physiol 54

      Pages: 331-337

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Tension- and afferent input-associated responses of neuromuscular system of rats to hindlimb unloading and/or tenotomy2004

    • Author(s)
      Kawano F, A Ishihara, JL Stevens, XD Wang, S Ohshima, M Horisaka, Y Maeda, I Nonaka, Y Ohira
    • Journal Title

      Am J Physiol Regul Integr Comp Physiol 287

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Heat stress facilitates the recovery of atrophied soleus muscle in rat2004

    • Author(s)
      Goto, K, M Honda, T Kobayashi, K Uehara, Kojima, T Akema, T Sugiura, S Yamada, Y Ohira, T Yoshioka
    • Journal Title

      Jpn J Physiol 54

      Pages: 285-293

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Hindlimb suspension inhibits air-righting due to altered recruitment of neck and back muscles in rats2004

    • Author(s)
      Kawano F, XD Wang, YB Lan, H Yoneshima, Ishihara, M Igarashi, Y Ohira
    • Journal Title

      Jpn J Physiol 54

      Pages: 229-242

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Metabolic modulation of muscle fiber properties unrelated to mechanical stimuli.2003

    • Author(s)
      Ohira, Y., F.Kawano, R.R.Roy, V.R.Edgerton.
    • Journal Title

      Jpn. J. Physiol. 53

      Pages: 389-400

    • NAID

      10012732881

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Effects of heat stress and mechanical stretch on protein expression in cultured skeletal muscle cells.2003

    • Author(s)
      Goto, K., R.Okuyama, H.Sugiyama, M.Honda, T.Kobayashi, K.Uehara, T.Akema, T.Sugiura, S.Yamada, Y.Ohira, T.Yoshioka.
    • Journal Title

      Pflugers Arch. - Eur. J. Physiol. 447

      Pages: 247-253

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Motoneuron and sensory neuron plasticity to varying neuromuscular activity levels.2003

    • Author(s)
      Ishihara, A., R.R.Roy, Y.Ohira, V.R.Edgerton.
    • Journal Title

      Exer. Sport Sci. Rev. 31

      Pages: 51-57

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Profiles of connectin (titin) in atrophied soleus muscle induced by unloading of rats.2003

    • Author(s)
      Goto, K., R.Okuyama, M.Honda, H.Uchida, T.Akema, Y.Ohira, T.Yoshioka
    • Journal Title

      J. Appl. Physiol. 94

      Pages: 897-902

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Effects of aging and exercise on density and cross-sectional area of femur in senescence-accelerated mouse prone 6.2003

    • Author(s)
      Ishihara, A., R.R.Roy, Y.Ohira, F.Kawano, K.Nonaka, K.Yamamoto, V.R.Edgerton
    • Journal Title

      J. Musculoskel. Neuron. Interact. 3

      Pages: 162-169

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Upregulation of HSP72 in reloading rat soleus muscle after prolonged hindlimb unloading.2003

    • Author(s)
      Oishi, Y., K.Taniguchi, H.Matsumoto, F.Kawano, A.Ishihara, Y.Ohira
    • Journal Title

      Jpn. J. Physiol. 53

      Pages: 281-286

    • NAID

      50000344632

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Differential responses of HSPs to heat stress in slow and fast regions of rat gastrocnemius muscle.2003

    • Author(s)
      Oishi, Y., K.Taniguchi, H.Matsumoto, A.Ishihara, Y.Ohira, R.R.Roy
    • Journal Title

      Muscle & Nerve 28

      Pages: 587-594

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Metabolic modulation of muscle fiber properties unrelated to mechanical stimuli.2003

    • Author(s)
      Ohira, Y, F.Kawano, R.R.Roy, V.R.Edgerton.
    • Journal Title

      Jpn.J.Physiol. 53

      Pages: 389-400

    • NAID

      10012732881

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Effects of heat stress and mechanical stretch on protein expression in cultured skeletal muscle cells.2003

    • Author(s)
      Goto, K., R.Okuyama, H.Sugiyama, M.Honda, T.Kobayashi, K.Uehara, T.Akema, T.Sugiura, S.Yamada, Y.Ohira, T.Yoshioka.
    • Journal Title

      Pflugers Arch.-Eur.J.Physiol. 447

      Pages: 247-253

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Motoneuron and sensory neuron plasticity to varying neuromuscular activity levels.2003

    • Author(s)
      Ishihara, A., R.R.Roy, Y.Ohira, V.R.Edgerton.
    • Journal Title

      Exer.Sport Sci.Rev. 31

      Pages: 51-57

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Profiles of connectin (titin) in atrophied soleus muscle induced by unloading of rats.2003

    • Author(s)
      Goto, K., R.Okuyama, M.Honda, H.Uchida, T.Akema, Y.Ohira, T.Yoshioka.
    • Journal Title

      J.Appl.Physiol. 94

      Pages: 897-902

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Effects of aging and exercise on density and cross-sectional area of femur in senescence-accelerated mouse prone 6.2003

    • Author(s)
      Ishihara, A., R.R.Roy, Y.Ohira, F.Kawano, K.Nonaka, K.Yamamoto, V.R.Edgerton.
    • Journal Title

      J.Musculoskel.Neuron.Interact. 3

      Pages: 162-169

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Upregulation of HSP72 in reloading rat soleus muscle after prolonged hindlimb unloading.2003

    • Author(s)
      Oishi, Y., K.Taniguchi, H.Matsumoto, F.Kawano, A.Ishihara, Y.Ohira.
    • Journal Title

      Jpn.J.Physiol. 53

      Pages: 281-286

    • NAID

      50000344632

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Differential responses of HSPs to heat stress in slow and fast regions of rat gastrocnemius muscle.2003

    • Author(s)
      Oishi, Y., K.Taniguchi, H.Matsumoto, A.Ishihara, Y.Ohira, R.R.Roy.
    • Journal Title

      Muscle & Nerve 28

      Pages: 587-594

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Role(s) of nucleoli, phosphorylation of ribosomal protein S6 and/or HSP27 in the regulation of muscle mass.

    • Author(s)
      Kawano, F., Y.Matsuoka, Y.Oke, Y.Higo, M.Terada, X.D.Wang, N.Nakai, H.Fukuda, S.Imajoh-Ohmi, Y.Ohira
    • Journal Title

      Am. J. Physiol. Cell Physiol. (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Effects of mechanical and neural stimuli on the properties of soleus muscle fibers in mdx mice.

    • Author(s)
      Lan, Y.B., M.Terada, Y.Higo, F.Kawano, Y.Matsuoka, X.D.Wang, N.Nakai, Y.Ohira
    • Journal Title

      Jpn. J. Aerosp. Environ. Med. (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Investigation of the mechanism responsible for muscle atrophy and countermeasures in microgravity environment : Role(s) of mechanical load and/or satellite cells.

    • Author(s)
      Ohira, Y., X.D.Wang, F.Kawano, M.Terada, Y.Matsuoka, Y.Higo, T.Ohira, A.Kojima, K.Goto, T.Yoshioka
    • Journal Title

      Proceedings for the International Symposium on Space Medicine, Sapporo (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Role(s) of nucleoli, phosphorylation of ribosomal protein S6 and/or HSP27 in the regulation of muscle mass.

    • Author(s)
      Kawano, F., Y.Matsuoka, Y.Oke, Y.Higo, M.Terada, X.D.Wang, N.Nakai, H.Fukuda, S.Imajoh-Ohmi, Y.Ohira.
    • Journal Title

      Am.J.Physiol.Cell Physiol. (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Effects of mechanical and neural stimuli on the properties of soleus muscle fibers in mdx mice.

    • Author(s)
      Lan, Y.B., M.Terada, Y.Higo, F.Kawano, Y.Matsuoka, X.D.Wang, N.Nakai, Y.Ohira.
    • Journal Title

      Jpn.J.Aerosp.Environ.Med. (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Investigation of the mechanism responsible for muscle atrophy and countermeasures in microgravity environment : Role(s) of mechanical load and/or satellite cells.

    • Author(s)
      Ohira, Y., X.D.Wang, F.Kawano, M.Terada, Y.Matsuoka, Y.Higo, T.Ohira, A.Kojima, K.Goto, T.Yoshioka.
    • Journal Title

      Proceedings for the International Symposium on Space Medicine, Sapporo (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Transcription regulation of gene expression in rat brown adipose tissue in response to unloading or 2G loading during growing period.

    • Author(s)
      Watanabe, S., Y.Hitomi, F.Kawano, Y.Ohira, T.Kizaki, N.Nakano, T.Sakurai, T.Izawa, K.Suzuki, M.Sudoh, R.R.Roy, H.Ohno.
    • Journal Title

      Acta Astronautica (in press)

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Effects of hyperbaric exposure with oxygen concentration on the physical activity of developing rats.

    • Author(s)
      Matsumoto, A., T.Okura, F.Morimatsu, Y.Ohira, A.Ishihara.
    • Journal Title

      Dev.Neurosci. (in press)

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Role(s) of nucleoli, phosphorylation of ribosomal protein S6 and/or HSP27 in the regulation of muscle mass.

    • Author(s)
      Kawano, F., Y.Matsuoka, Y.Oke, Y.Higo, M.Terada, X.D.Wang, N.Nakai, H.Fukuda, S.Imajoh-Ohmi, Y.Ohira.
    • Journal Title

      Am.J.Physiol.Cell Physiol. (in press)

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Effects of mechanical and neural stimuli on the properties of soleus muscle fibers in mdx mice.

    • Author(s)
      Lan, Y.B., M.Terada, Y.Higo, F.Kawano, Y.Matsuoka, X.D.Wang, N.Nakai, Y.Ohira.
    • Journal Title

      Jpn.J.Aerosp.Environ.Med. (in press)

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Investigation of the mechanism responsible for muscle atrophy and countermeasures in microgravity environment : Role(s) of mechanical load and/or satellite cells.

    • Author(s)
      Ohira, Y., X.D.Wang, F.Kawano, M.Terada, Y.Matsuoka, Y.Higo, T.Ohira, A.Kojima, K.Goto, T.Yoshioka.
    • Journal Title

      Proceeding for the International Symposium on Space Medicine, Sapporo. (in press)

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Mechanical load-dependent regulation of satellite cell and fiber size in rat soleus muscle.

    • Author(s)
      Wang, X.D., F.Kawano, Y.Matsuoka, K.Fukunaga, M.Terada, M.Sudoh, A.Ishihara, Y.Ohira.
    • Journal Title

      Am.J.Physiol.Cell.Physiol. (in press)

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Irreversible morphplogical changes in leg bone following chronic gravitational unloading of growing rats.

    • Author(s)
      Y.Ohira, F.Kawano, S.D.Wang, M.Sudoh, Y.Iwashita, H.J.Majima, I.Nonaka.
    • Journal Title

      Life Sci. (in press)

    • Related Report
      2005 Annual Research Report
  • [Book] 宇宙飛行士の体力。体力とはなにか-運動処方のその前に-(長澤純一(編))2007

    • Author(s)
      大平充宣
    • Publisher
      ナップ
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Book] 重力と気圧 : 宇宙。「環境生理学」(本間研一・彼末一之・編)2007

    • Author(s)
      大平充宣, 関口千春, 石井正則, 石原昭彦
    • Publisher
      北海道大学出版会
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Book] 微小重力環境への神経・筋の適応。生産と技術 58(3)2006

    • Author(s)
      大平充宣
    • Publisher
      社団法人生産技術振興協会
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Book] 微小重力環境での運動。学術の動向 102006

    • Author(s)
      大平充宣
    • Publisher
      日本学術会議
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Book] 生産と技術58(3) 微少重力環境への神経・筋の適応2006

    • Author(s)
      大平 充宣
    • Total Pages
      4
    • Related Report
      2006 Annual Research Report
  • [Book] 血液。生活習慣病対策および健康維持・増進のための運動療法と運動処方。(監修 : 佐藤祐造)2005

    • Author(s)
      大平充宣
    • Publisher
      文光堂
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Book] 身体能力の老化。(現代 老年精神医療、武田雅俊(編))2005

    • Author(s)
      後藤勝正, 大平充宣
    • Publisher
      永井書店
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Book] 加齢および廃用性筋萎縮と予防策。The Bone l92005

    • Author(s)
      後藤勝正, 大平充宣
    • Publisher
      メディカルレビュー社
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Book] 無重力環境への神経・筋の適応2004

    • Author(s)
      大平充宣, 河野史倫, 王暁東, 石原昭彦
    • Publisher
      日本マイクログラビティ学会
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Book] 現代 老年精神医療。 第一部.老化過程と高齢者4.身体の老化 身体能力の老化

    • Author(s)
      後藤 勝正, 大平 充宣
    • Publisher
      (仮称)(印刷中)
    • Related Report
      2006 Annual Research Report
  • [Book] 体力とは何か?宇宙飛行士

    • Author(s)
      大平 充宣
    • Publisher
      ナップ(印刷中)
    • Related Report
      2006 Annual Research Report
  • [Book] 運動療法実践ガイド。血液 : 一過性の運動に対する反応。

    • Author(s)
      大平 充宣
    • Publisher
      (印刷中)
    • Related Report
      2006 Annual Research Report
  • [Book] 宇宙。「環境生理学」。

    • Author(s)
      大平充宣, 関口千春, 石井正則, 石原昭彦
    • Publisher
      北海道大学図書刊行会(印刷中)
    • Related Report
      2006 Annual Research Report
  • [Publications] Ohira, Y., Kawano, F., Roy, R.R., Edgerton, V.R.: "Metabolic modulation of muscle fiber properties unrelated to mechanical stimuli"Jpn.J.Physiol.. 53. 389-400 (2003)

    • Related Report
      2003 Annual Research Report

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Published: 2003-04-01   Modified: 2016-04-21  

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