| Project/Area Number |
15209039
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Graduate School of Medical Science, Kyoto Prefectural University of Medicine |
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Principal Investigator |
NISHIMURA Tsunehiko Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Radiology, Professor, 医学研究科, 教授 (70237733)
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| Co-Investigator(Kenkyū-buntansha) |
USHIJIMA Yo Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Radiology, Assistant Professor, 医学研究科, 講師 (20275209)
YAMADA Kei Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Radiology, Assistant Professor, 医学研究科, 講師 (80315960)
KIZU Osamu Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Radiology, Assistant Professor, 医学研究科, 助手 (70305598)
ITO Hirotoshi Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Radiology, Assistant Professor, 医学研究科, 助手 (60360038)
大槻 克一 京都府立医科大学, 医学研究科, 助手 (90254325)
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| Project Period (FY) |
2003 – 2005
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| Project Status |
Completed (Fiscal Year 2005)
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| Budget Amount *help |
¥32,110,000 (Direct Cost: ¥24,700,000、Indirect Cost: ¥7,410,000)
Fiscal Year 2005: ¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000)
Fiscal Year 2004: ¥11,180,000 (Direct Cost: ¥8,600,000、Indirect Cost: ¥2,580,000)
Fiscal Year 2003: ¥14,560,000 (Direct Cost: ¥11,200,000、Indirect Cost: ¥3,360,000)
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| Keywords | Preventive Radiology / Coronary plaque / Multi slice CT / MR / Molecular Imaging / Fusion image / 冠動脈硬化イメージング / 不安定プラーク / 動脈硬化巣 / FDG-PET / 放射線予防医学 / 高速MRI技術 / ^<99m>Tc-Annexin |
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| Research Abstract |
There are few researches of preventive radiology on coronary sclerotic imaging, since many researches have been focused on ischemic heart disease until now. Recently, higher advance of multi-slice CT and MRI has made visualization of coronary arterial involvement including sclerosis and plaque. Furthermore, PET and SPECT has made active plaque deposition as molecular imaging. Our research has focused on integrated approach of coronary animal and human plaque imaging by CT/MR(anatomy) and PET/SPECT(function). In conclusion, coronary plaque imaging has been established by our integrated research. Furthermore, early detection of coronary sclerosis before ischemic heart disease(coronary stenosis) has made early cholesterol lowering therapy and decrease of medical fee and promotion of QOL.
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