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Development of MRI system for dentistry

Research Project

Project/Area Number 15209063
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Research Field Pathobiological dentistry/Dental radiology
Research InstitutionOkayama University

Principal Investigator

KATO Hirokazu  Okayama University, Medical School, Faculty of Health Sciences, Professor (60127511)

Co-Investigator(Kenkyū-buntansha) ASAUMI Jun-ichi  Okayama University, Hospital of Medicine and Dentistry, Senior Assistant Professor (60184131)
HONDA Yasutoshi  Okayama University, Graduate school of Medicine, Dentistry and Pharmaceutical Sciences, Assistant Professor (40284070)
YANAGI Yoshinobu  Okayama University, Hospital of Medicine and Dentistry, Assistant Professor (50284071)
TAKAHASHI Norio  Okayama University, Graduate School of Natural Science and Technology, Professor (40108121)
YAMAMOTO Yoshitake  Okayama University, Medical School, Faculty of Health Sciences, Professor (50032941)
岸 幹二  岡山大学, 大学院・医歯学総合研究科, 教授 (30033202)
Project Period (FY) 2003 – 2006
Project Status Completed (Fiscal Year 2006)
Budget Amount *help
¥39,130,000 (Direct Cost: ¥30,100,000、Indirect Cost: ¥9,030,000)
Fiscal Year 2006: ¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000)
Fiscal Year 2005: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2004: ¥13,130,000 (Direct Cost: ¥10,100,000、Indirect Cost: ¥3,030,000)
Fiscal Year 2003: ¥14,950,000 (Direct Cost: ¥11,500,000、Indirect Cost: ¥3,450,000)
KeywordsMRT / Dentistry / Unilateral magnet / NMR / Optimization / 歯科用MRI / unilateral MRI / one-sided型 MRI / 開磁路型磁気回路 / 緩和時間 / ファントム / 画像再構成
Research Abstract

To develop a small-sized MRI for dentistry, we developed an MRI phantom and designed a magnetic circuit. We then developed trial units of the magnetic circuit and of a maxillofacial MRI system, collected image data signals, and reconstructed the MR images. Based on this research, we applied for a patent on the unilateral magnetic circuit.
1. Development of phantom: We developed a phantom having human-tissue equivalent T1 and T2 relaxation times, and human-tissue-equivalent (except for fat) conductivity. Any shape of the phantom can be made, as it is in gel form.
2. Design of a magnetic circuit algorithm: A spatially uniform magnetic field is difficult to generate with a magnetic circuit using an open-type magnet because of its structure. To overcome this, we conceived a "scaled evolution strategy method", which enabled us to effectively reduce the number of objective functions.
3. Trial development of magnetic circuit: Based on the above design method, we developed a lateral magnetic circ … More uit.
4. Trial development of a maxillofacial MRI system: We developed a relatively small magnetic circuit into which the patient's head can be positioned. We also constructed an MRI unit, and reconstructed MR images from the obtained data.
5. Development of lateral magnetic circuit: Generally, the magnetic field of a unilateral magnetic circuit decreases with the increase of distance from the surface of the magnetic circuit. In our research, however, we designed a unilateral magnetic circuit having three-dimensionally uniform distribution in a target volume apart from the magnetic circuit surface. By means of combination of 16 magnetic blocks, the directions of the magnetic fields in the target region became parallel to the surface of the magnetic circuit. Using the 3-dimensional finite element method, a magnetic circuit 400 mm x 400 mm x 200 mm in size had a magnetic flux density of 64.5mT in a region of interest (ROI) 55 mm from the surface of the magnetic circuit. The uniformity was 28 ppm when the ROI size was 10 mm x 10 mm x 1 mm, and 613 ppm when 20 mm x 20 mm x 10 mm in size. Less

Report

(5 results)
  • 2006 Annual Research Report   Final Research Report Summary
  • 2005 Annual Research Report
  • 2004 Annual Research Report
  • 2003 Annual Research Report
  • Research Products

    (34 results)

All 2008 2007 2006 2005 2004 2003 Other

All Journal Article (22 results) Book (3 results) Patent(Industrial Property Rights) (2 results) Publications (7 results)

  • [Journal Article] Fundamental investigation of 3-D optimal design of open typemagnetic circuit producing uniform field2008

    • Author(s)
      Norio Takahashi
    • Journal Title

      The International Journal for Computation and Mathematics in Electrical and Electronic Englineering 27(1)

      Pages: 144-153

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Fundamental inverstigation of 3-D optimal design of open type magnetic circuit producing uniform field2008

    • Author(s)
      Norio, Takahashi, et. al.
    • Journal Title

      The International Journal for Computation and Mathematics in Electrical and Electronic Engineering 27

      Pages: 144-153

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Magnetic field generator and magnetic resonance imaging system with the magnetic field invented2007

    • Author(s)
      Hifirokazu, Kato, et. al.
    • Journal Title

      Foreign Application of Patent

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Magnetic field generator and magnetic resonance imaging system with the magnetic field invented2006

    • Author(s)
      Hirokazu, Kato, et. al.
    • Journal Title

      Patent in Japan 2006-209214

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Fundamental Investigation of 3-D Optimal Design of Open Type Magnetic Circuit Producing Uniform Field2006

    • Author(s)
      K. Akiyama, N. Takahashi, H. Kato, K. Kishi
    • Journal Title

      Proceedings ofEMF 2006

      Pages: 25-27

    • Related Report
      2006 Annual Research Report
  • [Journal Article] 小型MRIの作製2006

    • Author(s)
      加藤博和, 花元克巳, 山本尚武, ら
    • Journal Title

      医学物理 26Sup.2

      Pages: 93-94

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Composition of MRI phantoms equivalent to human tissues2005

    • Author(s)
      Hirokazu Kato
    • Journal Title

      Medical Physics 32(10)

      Pages: 3199-3208

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary 2005 Annual Research Report
  • [Journal Article] Composition of MRI phantoms enuivalent to human tissues2005

    • Author(s)
      Hirokazu, Kato, et. al.
    • Journal Title

      Medical Physics 32

      Pages: 3199-3208

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Development of a new hybrid gel phantom using carrageenan and gellan gum for visualizing three-dimensional tempreture distribution during hyperthermia and radiofrequency ablation2005

    • Author(s)
      Masahiro Kuroda
    • Journal Title

      International Journal of Oncology 27

      Pages: 175-184

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Development of a phantom compatible for MRI and hyperthermiausing carrageenan gel-relationship between dielectric properties and NaCl concentration2004

    • Author(s)
      Hirokazu Kato
    • Journal Title

      International Journal of Hyperthermia 20(5)

      Pages: 529-538

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] 開磁路型MRI装置の磁気回路に関する最適設計法の基礎的検討2004

    • Author(s)
      岡本吉史
    • Journal Title

      電気学会マグネティックス研究会 MAG-04-156

      Pages: 63-68

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary 2004 Annual Research Report
  • [Journal Article] Development of a phantom compatible for MRI and hyperthermia using carrageenan gel - relationship between dielectric properties and NaCl concentration2004

    • Author(s)
      Hirokazu, Kato, et. al.
    • Journal Title

      International Journal of Hyperthermia 20

      Pages: 529-538

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] The fundamental investigation of optimal design of magnetic circuit for open type MRI equipment2004

    • Author(s)
      Yoshifumi, Okamoto, et. al.
    • Journal Title

      Technical Meeting on Magnetics, IEE Japan MAG-04-156

      Pages: 63-68

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Development of a phantom compatible for MRI and hyperthermia using carrageenan gel -relationship between dielectric properties and NaCl concentration2004

    • Author(s)
      Hirokazu Kato
    • Journal Title

      International Journal of Hyperthermia 20(5)

      Pages: 529-538

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Development of a phantom compatible for MRI and hyperthermia using carrageenan gel - relationship between T1 and T2 values and NaCl concentration2004

    • Author(s)
      Atsushi Yoshida
    • Journal Title

      International Journal of Hyperthermia 20(8)

      Pages: 803-814

    • Related Report
      2004 Annual Research Report
  • [Journal Article] MRIにおけるサンプリング時間の測定と画像の再構成2004

    • Author(s)
      加藤博和
    • Journal Title

      岡山大学医学部保健学科紀要 14(2)

      Pages: 121-128

    • NAID

      120002307209

    • Related Report
      2004 Annual Research Report
  • [Journal Article] 教育・研究用小型MRIの開発-シ-ケンシャルパルスの生成-2004

    • Author(s)
      帆足正勝
    • Journal Title

      日本放射線技術学会雑誌 60(9)

      Pages: 1197-1197

    • Related Report
      2004 Annual Research Report
  • [Journal Article] 教育・研究用小型MRIの開発-傾斜磁場コイルの設計と作製-2004

    • Author(s)
      青山良宏
    • Journal Title

      日本放射線技術学会雑誌 60(9)

      Pages: 1196-1197

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Development of a tissue-equivalent MRI phantom using carrageenan gel2003

    • Author(s)
      Koichi Yoshimura
    • Journal Title

      Magnetic Resonance in Medicine 50

      Pages: 1011-1017

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Development of a tissue-equivalent MRI phantom using carrageenan gel2003

    • Author(s)
      Koichi, Yoshimura, et. al.
    • Journal Title

      Magnetic Resonance in Medicine 50

      Pages: 1011-1017

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] A design of permanent magnet array for unilateral NMR device

    • Author(s)
      Hirokazu Kato
    • Journal Title

      Concepts in Magnetic Resonance, Part B (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] A design of permanent magnet array for unilateral NMR device

    • Author(s)
      Hirokazu, Kato, et. al.
    • Journal Title

      Concepts in Magnetic Resonance, Part B (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Book] 放射線物理学2006

    • Author(s)
      遠藤真広
    • Total Pages
      302
    • Publisher
      オーム社
    • Related Report
      2005 Annual Research Report
  • [Book] 新・医用放射線技術実験2005

    • Author(s)
      田中 仁
    • Total Pages
      439
    • Publisher
      共立出版
    • Related Report
      2005 Annual Research Report
  • [Book] 標準MRI2004

    • Author(s)
      杉村和朗
    • Total Pages
      346
    • Publisher
      オーム社
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary 2004 Annual Research Report
  • [Patent(Industrial Property Rights)] 磁界生成器及びこの磁界生成器を備えた核磁気共鳴装置2007

    • Inventor(s)
      加藤博和, 他
    • Industrial Property Rights Holder
      岡山大学, 他
    • Filing Date
      2007-07-31
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Patent(Industrial Property Rights)] 磁界生成器及びこの磁界生成器を備えた核磁気共鳴装置2006

    • Inventor(s)
      加藤博和, 他
    • Industrial Property Rights Holder
      岡山大学, 他
    • Filing Date
      2006-07-31
    • Related Report
      2006 Annual Research Report
  • [Publications] 加藤博和: "ハイパーサーミア装置の操作ガイド III 腔内加温法"日本ハイパーサーミア誌. 19. 106-119 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] K.Yoshimura: "Development of a tissue-equivalent MRI phantom using carrageenan gel"Magnetic Resonance in Medicine. 50. 1011-1017 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 加藤博和: "MRIにおけるサンプリング時間の測定と画像の再構成"岡山大学医学部保健学科紀要. (accepted).

    • Related Report
      2003 Annual Research Report
  • [Publications] K.Shibuya: "A protein kinase inhibitor, promotes the development of thermotolerance in BHK21 and tsAF8 Cells"Japanese Journal of Hyperthermic Oncology. 19(4). 187-194 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] H.Kato: "Development of a phantom compatible for MRI and hyperthermia using carrageenan gel 1.Relationship between dielectric properties and NaCl..."International Journal of Hyperthermia. (accepted).

    • Related Report
      2003 Annual Research Report
  • [Publications] A.Yoshida: "Development of a phantom compatible for MRI and hyperthermia using carrageenan gel 2.Relationship between T1 and T2 values and NaCl..."International Journal of Hyperthermia. (accepted).

    • Related Report
      2003 Annual Research Report
  • [Publications] 伊藤公一: "人体電磁ファントムに関する調査研究の体系化"社団法人 電子情報通信学会. 50 (2003)

    • Related Report
      2003 Annual Research Report

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Published: 2003-04-01   Modified: 2016-04-21  

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