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The study of a new method of sentinel node detection in breast cancer using contrast-enhanced ultrasonography

Research Project

Project/Area Number 15300186
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Medical systems
Research InstitutionJICHI MEDICAL SCHOOL

Principal Investigator

OMOTO Kiyoka  JMS, School of Medicine, Assistant Professor, 医学部, 講師 (90306118)

Co-Investigator(Kenkyū-buntansha) TANIGUCHI Nobuyuki  JMS, School of Medicine, Associate Professor, 医学部, 助教授 (10245053)
ITOH Kouichi  JMS, School of Medicine, Professor, 医学部, 教授 (60095007)
HOZUMI Yasuo  JMS, School of Medicine, Associate Professor, 医学部, 助教授 (50260831)
Project Period (FY) 2003 – 2005
Project Status Completed (Fiscal Year 2005)
Budget Amount *help
¥6,200,000 (Direct Cost: ¥6,200,000)
Fiscal Year 2005: ¥1,100,000 (Direct Cost: ¥1,100,000)
Fiscal Year 2004: ¥2,800,000 (Direct Cost: ¥2,800,000)
Fiscal Year 2003: ¥2,300,000 (Direct Cost: ¥2,300,000)
Keywordscontrast-enhanced ultrasound / sentinel lymph node / breast cancer / albumin / lymph node metastasis / animal experiment / clinical evaluation / dye-guided method / リンパ節移 / センチネルリンパ節 / 超音波造影剤 / ガンマプローブ法
Research Abstract

In animal and clinical study using US contrast-enhanced with 25% albumin, SLNs were identified in all cases. The pathologic findings suggested our method may represent a new modality for SLN detection.
The another animal study by CE-US using a mixture of sulphan blue and hydroxyethylated starch indicated a good result, and its clinical study is planning.

Report

(4 results)
  • 2005 Annual Research Report   Final Research Report Summary
  • 2004 Annual Research Report
  • 2003 Annual Research Report
  • Research Products

    (14 results)

All 2006 2005 2004 2002

All Journal Article (13 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] Sentinel node detection in breast cancer using ultrasonography contrast-enhanced with 25% albumin- Initial clinical experience.2006

    • Author(s)
      Kiyoka Omoto
    • Journal Title

      J Clinical Ultrasound (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] New method of sentinel node detection by a combination of contrast-enhanced US and dye guidance : an animal study2006

    • Author(s)
      Kiyoka Omoto
    • Journal Title

      J Med Ultrasonics (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Sentinel node detection in breast cancer using ultrasonography contrast-enhanced with 25% albumin - Initial clinical experience.2006

    • Author(s)
      Kiyoka Omoto
    • Journal Title

      J Clinical Ultrasound. (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] New method of sentinel node detection by a combination of contrast-enhanced US and dye guidance : an animal study2006

    • Author(s)
      Kiyoka Omoto
    • Journal Title

      J Med Ultrasonics. (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] 造影超音波法による乳癌のセンチネルリンパ節同定の臨床応用2005

    • Author(s)
      尾本 きよか
    • Journal Title

      Digital Medicine 5(5)

      Pages: 23-25

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] 造影超音波法による乳癌のセンチネルリンパ節同定法2005

    • Author(s)
      尾本 きよか
    • Journal Title

      映像情報メディカル 37(8)

      Pages: 756-759

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Clinical evaluation of the sentinel node identification in breast cancer using contrast-enhanced ultrasonography.2005

    • Author(s)
      Kiyoka Omoto
    • Journal Title

      Digital Medicine 5(5)

      Pages: 23-25

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Sentinel node detection in breast cancer by contrast-enhanced ultrasonic imaging.2005

    • Author(s)
      Kiyoka Omoto
    • Journal Title

      Medical Imaging and Information 37(8)

      Pages: 756-759

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] 造影超音波画像による乳癌のセンチネルリンパ節同定法2005

    • Author(s)
      尾本きよか
    • Journal Title

      映像情報メディカル 37巻・8号

      Pages: 756-759

    • Related Report
      2005 Annual Research Report
  • [Journal Article] 造影超音波法による乳癌のセンチネルリンパ節同定の臨床応用2005

    • Author(s)
      尾本きよか
    • Journal Title

      Digital Medicine 5巻・5号

      Pages: 23-25

    • Related Report
      2005 Annual Research Report
  • [Journal Article] 超音波造影法によるセンチネルリンパ節の同定2004

    • Author(s)
      尾本 きよか
    • Journal Title

      別冊 医学のあゆみ 別冊

      Pages: 130-133

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Sentinel node detection using contrast-enhanced ultrasound.2004

    • Author(s)
      Kiyoka Omoto
    • Journal Title

      Igaku no ayumi extra number

      Pages: 130-133

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] 造影超音波法による乳癌のセンチネルリンパ節同定の臨床検討2004

    • Author(s)
      尾本 きよか 他
    • Journal Title

      超音波医学(学術集会プログラム・講演抄録集) Vol.31 supplement

    • NAID

      10014284319

    • Related Report
      2004 Annual Research Report
  • [Patent(Industrial Property Rights)] 超音波造影剤2002

    • Inventor(s)
      尾本きよか
    • Industrial Property Rights Holder
      尾本きよか
    • Filing Date
      2002-02-08
    • Acquisition Date
      2006-03-03
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary

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Published: 2003-04-01   Modified: 2016-04-21  

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