| Project/Area Number |
15350053
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Synthetic chemistry
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| Research Institution | National University Corporation Tokyo University of Agriculture and Technology |
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Principal Investigator |
CHIBA Kazuhiro National University Corporation Tokyo University of Agriculture and Technology, The Graduate School of Agricultural Science, Professor, 大学院・連合農学研究科, 教授 (20227325)
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| Co-Investigator(Kenkyū-buntansha) |
HASUMI Keiji National University Corporation Tokyo University of Agriculture and Technology, Department of Applied Biological Science, Professor, 大学院・共生科学技術研究部, 教授 (20208474)
KITANO Yoshikazu National University Corporation Tokyo University of Agriculture and Technology, Department of Applied Biological Science, Associate Professor, 大学院・共生科学技術研究部, 助教授 (10302910)
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| Project Period (FY) |
2003 – 2004
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| Project Status |
Completed (Fiscal Year 2004)
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| Budget Amount *help |
¥12,800,000 (Direct Cost: ¥12,800,000)
Fiscal Year 2004: ¥2,500,000 (Direct Cost: ¥2,500,000)
Fiscal Year 2003: ¥10,300,000 (Direct Cost: ¥10,300,000)
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| Keywords | Peptide / Biphasic System / Thermal Property / Organic Synthesis / Cyclohexane / Separation / ペプチド合成 / 液相合成 / 相溶 / 二相系 / コンビナトリアル合成 / オリゴペプチド / 分離精製法 |
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| Research Abstract |
A new thermomorphic organic solution system was introduced to accomplish wide variety of liquid-phase combinatorial chemistry. It was found that the combination of organic solutions composed of cycloalkanes and typical polar organic solvents formed phase-separable homogeneous solutions at ambient temperature. In this case, cycloalkanes effectively worked for the thermally sensitive phase-transformation. The cycloalkane phase separable systems were widely applied for several kind of liquid-phase combinatorial chemistry.
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