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Development of Positron Emission Tomography using Liquid Xenon Scintillation Detector System

Research Project

Project/Area Number 15360037
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Applied physics, general
Research InstitutionWaseda University

Principal Investigator

KIKUCHI Jun  Waseda University, Advanced Research Institute for Science and Engineering, Professor, 理工学総合研究センター, 教授 (50063665)

Co-Investigator(Kenkyū-buntansha) TERASAWA Kazuhiro  Waseda University, Advanced Research Institute for Science and Engineering, Lecturer, 理工学総合研究センター, 講師 (10329138)
MURAYAMA Hideo  National Institute of Radiological Sciences, Imaging Physics, Department of Medical Physics, Head of Imaging Physics, 重粒子医科学センター・医学物理部診断システム開発室, 室長 (50166310)
NISHIKIDO Fumihiko  Waseda University, Advanced Research Institute for Science and Engineering, Assistant, 理工学総合研究センター, 助手 (60367117)
Project Period (FY) 2003 – 2004
Project Status Completed (Fiscal Year 2004)
Budget Amount *help
¥11,200,000 (Direct Cost: ¥11,200,000)
Fiscal Year 2004: ¥1,400,000 (Direct Cost: ¥1,400,000)
Fiscal Year 2003: ¥9,800,000 (Direct Cost: ¥9,800,000)
Keywordspositron emission tomography (PET) / time of flight (TOF) / liquid xenon / time resolution / whole body PET / PET / 液体Xe / Xeシンチレーション / 液体Xe-PET / 低温用光電子増倍管 / 液体Xe用光電子増倍管
Research Abstract

The properties of liquid Xe are considered to be advantageous for application to time-of-flight position emission tomography (TOF-PET). Previously, we constructed a prototype liquid Xe TOF-PET detector using photomultiplier tubes(PMT), which can operate at liquid xenon temperature, and investigated their performance. Their poor quantum efficiency and low gain, however, were not sufficient for use in TOF-PET. Recently, new PMTs with five times higher quantum efficiency in liquid Xe and ten times higher gain than previous PMTs have been developed by Hamamatsu Photonics Co. The prototype PET detectors, presented here, were constructed using these new PMTs and tested. An energy resolution of 15.9% (FWHM), a position resolution of 2.1- 3.5mm (FWHM), and a timing resolution of 260 ps (FWHM) were achieved.

Report

(3 results)
  • 2004 Annual Research Report   Final Research Report Summary
  • 2003 Annual Research Report
  • Research Products

    (11 results)

All 2005 2004 2003 Other

All Journal Article (10 results) Publications (1 results)

  • [Journal Article] Performance of a prototype of liquid xenon scintillation detector system for time-of-flight type positron emission tomography with improved photomultipliers2005

    • Author(s)
      F.Nishikido, T.Doke, J.Kikuchi, T.Mori, H.Murayama, T.Ooshita, H.Takahasi
    • Journal Title

      Japanese Journal of Applied Physics Vol.44, No.7A

      Pages: 5193-5198

    • NAID

      10016609752

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Scintillation response of liquid Xe surrounded by PTFE reflector for gamma rays2004

    • Author(s)
      M.Yamashita, T.Doke, K.Kawasaki, J.Kikuchi, S.Suzuki
    • Journal Title

      Nuclear Instruments and Methods in Physics Research A 535

      Pages: 692-698

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Performance of a prototype of liquid xenon scintillation detector system for positron emission tomography2004

    • Author(s)
      F.Nishikido, T.Doke, J.Kikuchi, T.Mori
    • Journal Title

      Japanese Journal of Applied Physics Vol.. No.2

      Pages: 779-784

    • NAID

      10012040917

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Performance of a prototype of liquid xenon scintillation detector system for positron emission tomography2004

    • Author(s)
      F.Nishikido, T.Doke, J.Kikuchi, T.Mori
    • Journal Title

      Japanese Journal of Applied Physics Vol.43, No.2

      Pages: 779-784

    • NAID

      10012040917

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Performance of a Prototype of Liquid Xenon Scintillation Detector System for Positron Emission Tomography2004

    • Author(s)
      F.Nishikido, T.Doke, J.Kikuchi et al.
    • Journal Title

      Jpn.J.Appl.Phys. Vol.43

      Pages: 779-784

    • NAID

      10012040917

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Capacitive level meter for liquid rare gases2003

    • Author(s)
      R.Sawada, J.Kikuchi, E.Shibamura, M.Yamashita, T.Yoshimura
    • Journal Title

      Cryogenics 43

      Pages: 449-450

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Time-of-flight position emission tomography using liquid Xenon Scintillation

    • Author(s)
      T.Doke, J.Kikuchi, F.Nishikido
    • Journal Title

      Nuclear Instruments and Methods in Physics Research A (to be published)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Development of liquid Xe scintillation time of flight type positron emission tomography

    • Author(s)
      Fumihiko Nishikido
    • Journal Title

      博士論文

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Time-of-flight position emission tomography using liquid Xenon Scintillation

    • Author(s)
      T.Doke, J.Kikuchi, F.Nishikido
    • Journal Title

      Nuclear Instruments and Methods in Physics Research A (to be published)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Development of liquid Xe scintillation time of flight type positron emission tomography

    • Author(s)
      Fumihiko Nishikido
    • Journal Title

      a thesis for a doctor's degree

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Publications] F.Nishikido, T.Doke, J.Kikuchi, T.Mori, K.Takizawa, M.Yamamoto: "Performance of a prototype of liquid xenon scintillation detector system for positron emission tomography"Japanese Journal of Applied Physics. Vol.43, No.2. 779-784 (2004)

    • Related Report
      2003 Annual Research Report

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Published: 2003-04-01   Modified: 2016-04-21  

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