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Miniaturization and Performance Enhancement of the Magnetically Levitated Centrifugal Pump as an Implantable Ventricular Assist Device

Research Project

Project/Area Number 15390425
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Thoracic surgery
Research InstitutionResearch Institute of National Cardiovascular Center

Principal Investigator

TAENAKA Yoshiyuki  National Cardiovascular Center, Department of Artificial Organs, Director, 人工臓器部, 部長 (00142183)

Co-Investigator(Kenkyū-buntansha) TATSUMI Eisuke  National Cardiovascular Center, Department of Research Evaluation, Division Head, 研究評価室, 室長 (00216996)
MASUZAWA Toru  Ibaraki University, Department of Mechanical Engineering, Professor, 工学部, 教授 (40199691)
TAKEWA Yoshiaki  National Cardiovascular Center, Department of Artificial Organs, Division Head, 人工臓器部, 室長 (20332405)
HOMMA Akihiko  National Cardiovascular Center, Department of Artificial Organs, Research Staff, 人工臓器部, 室員 (20287428)
TSUKIYA Tomonori  National Cardiovascular Center, Department of Artificial Organs, Research Staff, 人工臓器部, 室員 (00311449)
Project Period (FY) 2003 – 2005
Project Status Completed (Fiscal Year 2005)
Budget Amount *help
¥13,800,000 (Direct Cost: ¥13,800,000)
Fiscal Year 2005: ¥2,100,000 (Direct Cost: ¥2,100,000)
Fiscal Year 2004: ¥5,700,000 (Direct Cost: ¥5,700,000)
Fiscal Year 2003: ¥6,000,000 (Direct Cost: ¥6,000,000)
Keywordsmagnetic levitation / centrifugal pump / ventricular assist device / computation fluid dynamics / 人工心臓 / ゼロパワー制御 / 磁気軸受 / 数値流体解析
Research Abstract

The purpose of the present study is enhancement of the performances and the biocompatibility of the centrifugal pump with magnetically levitated impeller as a left ventricular assist device, with the final goal of development of an implantable ventricular assist system.
The primary results obtained through this study are as follows;
1. Miniaturization and Stability Enhancement of the Levitation Controlling Circuit
The electronic circuits which control both radial levitation and rotation of the rotor (impeller) were designed to be implemented in the compact centrifugal pump. Numerical Simulations were carried out to obtain the optimized values of the inner/outer diameters of the stator, and the number of turns. The test rig pump was designed based on the analyses results, and the sufficient hydrodynamic performances were realized as a left ventricular assist device.
2. The zero-power control method was employed and implemented into the present levitation system. The zero-power system sets t … More he control target onto the position where the radial fluid forces are minimized, and consequently save the electric power required to the levitation system. We built the numerical modeling of the electromagnetic components and then obtained the optimized thickness of the permanent magnets, diameter of the stator, and the number of turns of electric coils. Finally the diameter of the stator was set to 55 mm and we have succeeded in reducing the total electric power to 11 watts.
3. The smallest clearance of the blood passage was 0.5 mm at the gap between the stator and the rotor. The hemolysis tesing was carried out to confirm the mechanical damage exerted to the red blood cells are within tolerable range toward clinical application. The results showed that the mechanical blood damage caused by the pump are compatible to that by the commercially available pump (Medtronic BP-80) at the flow rate of 5.0 L/min against the pressure head of 100 mmHg.
4. The method of estimating the flow rate of the pump are also investigated. As the result of the zero-power control, the impeller positions shift to the balanced position on each flow condition. We have found the displacement of the impeller from the geometrical center are proportional to the flow rate. This basic founding can be developed into the flow rate measurement system which does not require any flow meter in the system. Less

Report

(4 results)
  • 2005 Annual Research Report   Final Research Report Summary
  • 2004 Annual Research Report
  • 2003 Annual Research Report
  • Research Products

    (20 results)

All 2005 2004 Other

All Journal Article (18 results) Publications (2 results)

  • [Journal Article] アキシャル型磁気浮上モータを用いた人工心臓用遠心ポンプの開発2005

    • Author(s)
      小沼弘幸, 増澤徹, 加藤勇
    • Journal Title

      日本機械学会論文集(C編) 71-701

      Pages: 93-99

    • NAID

      110006264499

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] 人工心臓用ラジアル型磁気浮上遠心ポンプの最適化2005

    • Author(s)
      小沼弘幸, 岡田養二, 増澤徹
    • Journal Title

      第17回バイオエンジニアリング講演会講演論文集 04-17

      Pages: 193-194

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] 人工心臓応用を目指した新しいハイブリッド型磁気軸受の開発2005

    • Author(s)
      斉藤喬, 中山直久, 増澤徹
    • Journal Title

      電気学会研究会資料 LD-05-46

      Pages: 11-16

    • NAID

      10017108549

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] 人工心臓用磁気浮上モータの小型化と高効率化2005

    • Author(s)
      増澤徹, 加藤裕介
    • Journal Title

      電気学会研究会資料 LD-05-48

      Pages: 23-28

    • NAID

      10017108561

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Magnetically Levitated Rotary Artificial Heart Pump with Axially Suspended Motor2005

    • Author(s)
      Onuma H, Masuzawa T, Kato T
    • Journal Title

      Transactions of the Japan Sciety of Mechanical Engineering, Series C 71-701

      Pages: 93-99

    • NAID

      110006264499

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Optimization of the Radially Maglev Centrifugal Pump for Artificial Heart2005

    • Author(s)
      Onuma H, Okada Y, Masuzawa T
    • Journal Title

      Proc.JSME 17^<th> Bioengineering Conference 04-17

      Pages: 193-194

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Novel Hybrid Type Magnetic Bearing for Artificial Hearts2005

    • Author(s)
      Saito T, Nakayama N, Masuzawa T
    • Journal Title

      The Papers of Technical Meeting on Linear Drives, IEE Japan LD-05-46

      Pages: 11-16

    • NAID

      10017108549

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Miniaturization and Efficiency Improvement of Maglev Motor for Artificial Heart2005

    • Author(s)
      Masuzawa T, Kato Y
    • Journal Title

      The Papers of Technical Meeting on Linear Drives, IEE Japan LD-05-48

      Pages: 23-28

    • NAID

      10017108561

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] アキシャル型磁気浮上モータを用いた人工心臓の開発2004

    • Author(s)
      小沼弘幸, 増澤徹
    • Journal Title

      第16回バイオエンジニアリング講演会講演論文集 03-38

      Pages: 249-250

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] 磁気浮上人工心臓におけるゼロパワー制御2004

    • Author(s)
      増澤徹, 小沼弘幸, 岡田養二
    • Journal Title

      第47回自動制御連合講演会 04-256

      Pages: 322-322

    • NAID

      130004599398

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] 磁気浮上遠心ポンプ内の流体力とゼロパワー制御2004

    • Author(s)
      増澤徹, 小沼弘幸, 岡田養二, 築谷朋典, 巽英介, 妙中義之
    • Journal Title

      日本機械学会82期流体工学部門講演会 04-25

      Pages: 718-718

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Magnetically Levitated Artificial Heart with an Axially Suspended Motor2004

    • Author(s)
      Onuma H, Masuzawa T
    • Journal Title

      Proc.JSME 16^<th> Conference of Bioengineering

      Pages: 249-250

    • NAID

      110002484186

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Zero Power Control for Magnetically Suspended Artificial Heart2004

    • Author(s)
      Masuzawa T, Onuma H, Okada Y
    • Journal Title

      Proc.47^<th> Automatic Control Conference 04-256

    • NAID

      130004599398

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Fluid Force Estimation and Zero Power Control of the Magnetically Suspended Centrifugal Blood Pump2004

    • Author(s)
      Masuzawa T, Onuma H, Okada Y, Tsukiya T, Tatsumi E, Taenaka Y
    • Journal Title

      Proc.JSME 82^<nd> Fluid Engineering Conference 718

    • NAID

      110004071012

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] 径方向支持型磁気浮上モータを用いた完全磁気浮上遠心血液ポンプの改良2004

    • Author(s)
      小沼弘幸, 増澤徹, 岡田養二, 築谷朋典, 妙中義之
    • Journal Title

      生体医工学,第42巻特別号第43回日本エム・イー学会大会プログラム・論文集 42

      Pages: 342-342

    • Related Report
      2004 Annual Research Report
  • [Journal Article] 径方向支持型磁気浮上モータを使用した人工心臓用遠心ポンプの改良2004

    • Author(s)
      小沼弘幸, 増澤徹, 岡田養二, 築谷朋典, 妙中義之
    • Journal Title

      第2回生活支援工学系学会連合大会 講演予稿集

      Pages: 167-168

    • NAID

      130001056082

    • Related Report
      2004 Annual Research Report
  • [Journal Article] 径方向支持型磁気浮上遠心ポンプの開発と溶血特性の評価2004

    • Author(s)
      小沼弘幸, 増澤徹, 岡田養二, 築谷朋典, 妙中義之
    • Journal Title

      第42回日本人工臓器学会大会予稿集 33,2

    • Related Report
      2004 Annual Research Report
  • [Journal Article] 磁気浮上遠心ポンプ内の流体力とゼロパワー制御2004

    • Author(s)
      増澤徹, 小沼弘幸, 岡田養二, 築谷朋典, 巽英介, 妙中義之
    • Journal Title

      日本機械学会流体工学部門講演会講演論文集 4-25

      Pages: 269-269

    • Related Report
      2004 Annual Research Report
  • [Publications] 小沼弘幸, 増澤徹, 大島郁也, 近藤良, 岡田養二: "実用化にむけた磁気浮上型人工心臓の開発"平成15年度茨城大学第2回SVBL成果報告会. 66-67 (2004)

    • Related Report
      2003 Annual Research Report
  • [Publications] 野津英孝, 小沼弘幸, 増澤徹, 岡田養二, 築谷朋典, 妙中義之: "ラジアル型磁気浮上人工心臓の改良に関する研究"人と福祉を支える技術フォーラム. A7 (2004)

    • Related Report
      2003 Annual Research Report

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Published: 2003-04-01   Modified: 2016-04-21  

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