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Evaluations of the motor functions of the elderly peoples in a cohort and development the methods to maintain or promote the motor functions.

Research Project

Project/Area Number 15390455
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Orthopaedic surgery
Research InstitutionNagoya University

Principal Investigator

HASEGAWA Yukiharu  Nagoya University, Graduate School of Medicine, Associate Professor, 大学院医学系研究科, 助教授 (50208500)

Co-Investigator(Kenkyū-buntansha) HATTA Yukiharu  Nagoya University, Graduate School of Medicine, Professor, 大学院環境学研究科, 教授 (80030469)
MATSUYAMA Yukhiro  Nagoya University, Graduate School of Medicine, Associate Professor, 大学院医学系研究科, 助教授 (20312316)
MASUI Tetsuo  Nagoya University, University Hospital, Medical Staff, 医学部附属病院, 医員 (50378113)
YAMAGUCHI Jin  Nagoya University, University Hospital, Medical Staff, 医学部附属病院, 医員 (00420381)
伊藤 宜則 (伊藤 宣則)  藤田保健衛生大学, 衛生学部, 教授 (50087665)
川崎 雅史  名古屋大学, 医学部附属病院, 医員 (60378106)
坂野 真士  名古屋大学, 大学院・医学系研究科, 助教授 (10324427)
Project Period (FY) 2003 – 2006
Project Status Completed (Fiscal Year 2006)
Budget Amount *help
¥13,000,000 (Direct Cost: ¥13,000,000)
Fiscal Year 2006: ¥2,000,000 (Direct Cost: ¥2,000,000)
Fiscal Year 2005: ¥1,800,000 (Direct Cost: ¥1,800,000)
Fiscal Year 2004: ¥1,700,000 (Direct Cost: ¥1,700,000)
Fiscal Year 2003: ¥7,500,000 (Direct Cost: ¥7,500,000)
KeywordsMuscle and skeletal disorders / Cohort study / Osteoporosis / Osteoarthritis of the knee / Fall / Muscle strength / Quality of life / Cognitive function / 骨祖鬆症 / 変形性膝関節症 / 変形性脊椎症 / 疫学的研究 / 記名力 注意力
Research Abstract

The rapid increase of the elderly peoples will be a heavy burden for financially and socially in Japan. The second reason for the bed-ridden is the muscle and skeletal disorders such as hip fracture due to osteoporosis or osteoarthritis of the knee. Our purposes of this investigation are to evaluate of the motor functions of the elderly peoples and to develop some methods to maintain the functions in a cohort. We made epidemiological investigation for four years in Y town. Every year we performed the knee and lumber clinical and radiographic examination, questionnaire for activity, bone mineral density, performance test, strength ergometer, quality of life (SF36), fall record, and laboratory blood examinations. We collected all these data for ten years. We found many relationship between osteoarthritis of the knee and IL1bata polymorphism, and osteoporosis and ALDH2 polymorphism. Postural sway increased in rural community living elderly peoples. Cognitive functions were significantly related with walking speed and muscle strength. In the pilot study for three months we found muscle function was significantly better in the cognitive group "Monowasure Yobou group" than muscle exercise group "Netakiri Yobou group".
Further longitudinal studies were needed to find a ten-year changes: the motor functions, osteoarthritis of the knee, degenerative changes of the lumbar spine, osteoporosis and postural sway, and quality of life. These data will be useful for the maintenance and improving the motor functions and daily activities for the elderly peoples in the world.

Report

(5 results)
  • 2006 Annual Research Report   Final Research Report Summary
  • 2005 Annual Research Report
  • 2004 Annual Research Report
  • 2003 Annual Research Report
  • Research Products

    (51 results)

All 2007 2006 2005 2004 2003 Other

All Journal Article (43 results) Book (2 results) Publications (6 results)

  • [Journal Article] Osteoarthritis after Eccentric Rotational Acetabular Osteotomy.2007

    • Author(s)
      Hasegawa Y, Masui T, Yamaguchi J, Kawabe K, Suzuki S
    • Journal Title

      Clin Orthop Relat Res. (Inpress)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Childbirth and Sexual Activity after Eccentric Rotational Acetabular Osteotomy.2007

    • Author(s)
      Masui T, Hasegawa Y, Yamaguchi J, Kanoh T, Ishiguro N
    • Journal Title

      Clin Orthop Relat Res. (Inpress)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Osteoarthritis after Eccentric Rotational Acetabular Osteotomy.2007

    • Author(s)
      Yukiharu Hasegawa, Tetuso Masui, Jin Yamaguchi, Kiyoharu Kawabe, Sadao Suzuki et al.
    • Journal Title

      Clin Orthop Relat Res. (In press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Childbirth and Sexual Activity after Eccentric Rotational Acetabular Osteotomy.2007

    • Author(s)
      Masui T, Hasegawa Y, Yamaguchi J, Kanoh T, Ishiguro N. et al.
    • Journal Title

      Clin Orthop Relat Res. (In press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Osteoarthritis after Eccentric Rotational Acetabular Osteotomy.2007

    • Author(s)
      Hasegawa Y, Masui T, Yamaguchi J, Kawabe K, Suzuki S
    • Journal Title

      Clin Orthop Relat Res. (In press)

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Childbirth and Sexual Activity after Eccentric Rotational Acetabular Osteotomy.2007

    • Author(s)
      Masui T, Hasegawa Y, Yamaguchi J, Kanoh T, Ishiguro N
    • Journal Title

      Clin Orthop Relat Res. (In press)

    • Related Report
      2006 Annual Research Report
  • [Journal Article] ALDH2 polymorphisms and bone mineral density in an elderly Japanese population.2006

    • Author(s)
      Yamaguchi J, Hasegawa Y, Kawasaki M, Masui T, Kanoh T, Ishiguro N, Hamajima N
    • Journal Title

      Osteoporos Int 17

      Pages: 908-913

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Increasing postural sway in rural-community-dwelling elderly persons with knee osteoarthritis.2006

    • Author(s)
      Masui T, Hasegawa Y, Yamaguchi J, Kanoh T, Ishiguro N, Suzuki S
    • Journal Title

      J Orthop Sci 11(4)

      Pages: 353-358

    • NAID

      10018227094

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] ALDH2 polymorphisms and bone mineral density in an elderly Japanese population.2006

    • Author(s)
      Jin Yamaguchi, Yukiharu Hasegawa, Masashi Kawasaki, Tetsuo Masui, Toshiya Kanoh, Naoki Ishiguro, Nobuki Hamajima et al.
    • Journal Title

      Osteoporos Int 17

      Pages: 908-913

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Increasing postural sway in rural-community-dwelling elderly persons with knee osteoarthritis.2006

    • Author(s)
      Tetsuo Masui, Yukiharu Hasegawa, Jin Yamaguchi, Toshiya Kanoh, Naoki Ishiguro, Sadao Suzuki et al.
    • Journal Title

      J Orthop Sci. 11(4)

      Pages: 353-8

    • NAID

      10018227094

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Increasing postural sway in rural-community-dwelling elderly persons with knee osteoarthritis2006

    • Author(s)
      Masui T, Hasegawa Y, Yamaguchi J, T Kanoh T, Ishiguro N, Suzuki S
    • Journal Title

      J Orthop Sci 11

      Pages: 353-353

    • NAID

      10018227094

    • Related Report
      2006 Annual Research Report
  • [Journal Article] ALDH2 polymorphisms and bone mineral density in an elderly Japanese population2006

    • Author(s)
      Yamaguchi J, Hasegawa Y, Kawasaki M, Masui T, Kanoh T, Ishiguro N, Hamajima N
    • Journal Title

      Osteoporos Int 17

      Pages: 908-908

    • Related Report
      2006 Annual Research Report
  • [Journal Article] ADL・QOLはこんなに制限されている2006

    • Author(s)
      坪井真幸, 長谷川幸治
    • Journal Title

      Journal of Clinical Rehabilitation 15

      Pages: 18-23

    • Related Report
      2006 Annual Research Report
  • [Journal Article] 中高年者の運動習慣と認知機能との関連について2006

    • Author(s)
      八田武志, 永原直子, 伊藤恵美, 伊藤宣則, 青木國雄
    • Journal Title

      人間環境学研究 4(1)

      Pages: 17-22

    • NAID

      130004545632

    • Related Report
      2006 Annual Research Report
  • [Journal Article] ALDH2 polymorphism and bone mineral density in a Japanese elderly population.2006

    • Author(s)
      Yamaguchi J, Hasegawa Y, Kawasaki M, Masui T, Kanoh T, Ishiguro N, Hamajima N
    • Journal Title

      Osteoporosis Int (in press)

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Lower-limb asymmetries in early and late middle age.2005

    • Author(s)
      Hatta T, Ito Y, Matsuyama Y, Hasegawa Y
    • Journal Title

      Laterality 10

      Pages: 267-277

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Gender differences in platform measures of balance in rural community-dwelling elders.2005

    • Author(s)
      Masui T, Hasegawa Y, Matsuyama Y, Sakano S, Kawasaki M, Suzuki S
    • Journal Title

      Arch Gerontol Geriatr. 41

      Pages: 201-209

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Total hip arthroplasty after failed transtrochanteric rotational osteotomy for avascular necrosis of the femoral head.2005

    • Author(s)
      Kawasaki M, Hasegawa Y, Sakano S, Masui T, Ishiguro N
    • Journal Title

      J Arthroplasty 20

      Pages: 574-579

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Expression of inflammatory cytokines, RANKL and OPG induced by titanium, cobalt-chromium and polyethylene particles.2005

    • Author(s)
      Masui T, Sakano S, Hasegawa Y, Warashina H, Ishiguro N
    • Journal Title

      Biomaterials 26

      Pages: 1695-1702

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Lower-limb asymmetries in early and late middle age.2005

    • Author(s)
      Takeshi Hatta, Yasuhiro Ito, Yukihiro Matsuyama, Yukiharu Hasegawa et al.
    • Journal Title

      Laterality 10

      Pages: 267-277

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Gender differences in platform measures of balance in rural community-dwelling elders.2005

    • Author(s)
      Tetsuo Masui, Yukiharu Hasegawa, Yukihiro Matsuyama, Shinji Sakano, Masashi Kawasaki, Sadao Suzuki et al.
    • Journal Title

      Arch Gerontol Geriatr. 41

      Pages: 201-209

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Total hip arthroplasty after failed transtrochanteric rotational osteotomy for avascular necrosis of the femoral head.2005

    • Author(s)
      Masashi Kawasaki, Yukiharu Hasegawa, Shinji Sakano, Tetsuo Masui, Naoki Ishiguro et al.
    • Journal Title

      J Arthroplasty 20

      Pages: 574-579

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Expression of inflammatory cytokines, RANKL and OPG induced by titanium, cobalt-chromium and polyethylene particles.2005

    • Author(s)
      Tetsuo Masui, Shinji Sakano, Yukiharu Hasegawa, Hideki Warashina, Naoki Ishiguro et al.
    • Journal Title

      Biomaterials. 26

      Pages: 1695-1702

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] An Objective Evaluation of Trunk Muscle Oxygen Count in Patients with Chronic Low Back Pain. Abstract of Japanese2005

    • Author(s)
      Yoshihito S, Yukihiro M, Hisatake Y, Yoshihito K, Hiroshi N, Shojiro N, Yukiharu H, Naoki I
    • Journal Title

      Orthoppaedic association 79(3)

    • Related Report
      2005 Annual Research Report
  • [Journal Article] 大腿骨近位部骨折における左右差の検討2005

    • Author(s)
      長谷川幸治
    • Journal Title

      日本整形外科学会誌 79(3)

    • Related Report
      2005 Annual Research Report
  • [Journal Article] 住民検診におけるエルゴメーターを用いた下肢筋力測定の5年間の縦断的研究2005

    • Author(s)
      山口仁, 長谷川幸治, 川崎雅史, 増井徹男, 山口仁, 加納稔也, 石黒直樹
    • Journal Title

      日本整形外科学会誌 79(3)

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Short Form 36(SF36)による生活の質(QOL)と変形性膝関節症の関係についての検討2005

    • Author(s)
      坪井真幸, 長谷川幸治, 川崎雅史, 増井徹男, 山口仁, 加納稔也, 石黒直樹
    • Journal Title

      日本整形外科学会誌 79(3)

    • Related Report
      2005 Annual Research Report
  • [Journal Article] 健常中高年における腰痛の疫学的検討 -縦・横VASとSF-36の関係2005

    • Author(s)
      中村博司, 松山幸弘, 吉原永武, 酒井義人, 片山良仁, 中島正二郎, 長谷川幸治, 石黒直樹
    • Journal Title

      日本整形外科学会誌 79(3)

    • Related Report
      2005 Annual Research Report
  • [Journal Article] 変形性膝関節症と遺伝子多型2005

    • Author(s)
      加納稔也, 長谷川幸治, 川崎雅史, 増井徹男, 山口仁, 石黒直樹, 浜島信之
    • Journal Title

      日本整形外科学会誌 79(3)

    • Related Report
      2005 Annual Research Report
  • [Journal Article] 骨粗鬆症の遺伝子多型2005

    • Author(s)
      長谷川幸治, 加納稔也, 石黒直樹
    • Journal Title

      第49回日本リウマチ学会抄録集

      Pages: 255-255

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Relation between the prefrontal cortex and cerebro-cerebellar functions : evidence from the results of stabilometrical indexes.2004

    • Author(s)
      Hatta T, Masui T, Ito Y, Ito E, Hasegawa Y, Matsuyama Y
    • Journal Title

      Applied Neuropsychology. 11

      Pages: 153-160

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Ectopic bone formation around the poly-L-lactide screw head in rotational acetabular osteotomy for hip dysplasia.2004

    • Author(s)
      Hasegawa Y, Sakano S, Kawabe K
    • Journal Title

      J Orthop Sci. 9

      Pages: 551-554

    • NAID

      10014115632

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Curved intertrochanteric varus osteotomy for osteonecrosis of the femoral head.2004

    • Author(s)
      Sakano S, Hasegawa Y, Torii Y, Kawasaki M, Ishiguro N
    • Journal Title

      J Bone Joint Surg Br 86-B

      Pages: 359-365

    • NAID

      40019177388

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Relation between the prefrontal cortex and cerebro-cerebellar functions : evidence from the results of stabilometrical indexes.2004

    • Author(s)
      Takeshi Hatta, Tetuso Masui, Yasuhiro Ito, Emi Ito, Yukiharu Hasegawa, Matsuyama Y et al.
    • Journal Title

      Applied Neuropsychology. 11

      Pages: 153-160

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Ectopic bone formation around the poly-L-lactide screw head in rotational acetabular osteotomy for hip dysplasia.2004

    • Author(s)
      Yukiharu Hasegawa, Shinji Sakano, Kiyoharu Kawabe et al.
    • Journal Title

      J Orthop Sci. 9

      Pages: 551-554

    • NAID

      10014115632

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Curved intertrochanteric varus osteotomy for osteonecrosis of the femoral head.2004

    • Author(s)
      Shinji Sakano, Yukiharu Hasegawa, Yukio Torii, Masashi Kawasaki, Naoki Ishiguro et al.
    • Journal Title

      J Bone Joint Surg Br 86-B

      Pages: 359-365

    • NAID

      40019177388

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] 尿中ピリジノリン・デオキシピリジノリン値と5年間の骨密度変化に関する縦断的研究2004

    • Author(s)
      山口 仁, 長谷川 幸治, 坂野 真士, 川崎 雅史, 加納 稔也, 石黒 直樹
    • Journal Title

      日本整形外科学会雑誌 78(3)

    • Related Report
      2004 Annual Research Report
  • [Journal Article] 腰背筋運動中における筋肉内酸素動態2004

    • Author(s)
      酒井 義人, 松山 幸弘, 吉原 永武, 辻 太一, 中村 博司, 長谷川 幸治, 石黒 直樹
    • Journal Title

      日本整形外科学会雑誌 78(4)

    • Related Report
      2004 Annual Research Report
  • [Journal Article] 一般住民における運動機能評価と重心動揺2004

    • Author(s)
      増井 徹男, 長谷川 幸治, 坂野 真士, 川崎 雅史, 山口 仁, 石黒 直樹
    • Journal Title

      日本整形外科学会雑誌 78(4)

    • Related Report
      2004 Annual Research Report
  • [Journal Article] 変形性股関節症の手術後はどのようなスポーツを許可すべきか?2004

    • Author(s)
      川崎 雅史, 長谷川 幸治, 坂野 真士, 増井 徹男, 山口 仁, 加納 稔也, 石黒 直樹
    • Journal Title

      日本整形外科学会雑誌 78(4)

    • Related Report
      2004 Annual Research Report
  • [Journal Article] 大腿骨近位部骨折受傷後10年間の死亡率と歩行能力2004

    • Author(s)
      坪井 真幸, 長谷川 幸治, 北村 伸二, Wingstrand Hans, Thorngren K・G, 石黒 直樹
    • Journal Title

      日本整形外科学会雑誌 78(3)

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Pedicle bone grafting versus transtrochanteric rotational osteotomy for avascular necrosis of the femoral head.2003

    • Author(s)
      Hasegawa Y, Sakano S, Iwase T, Iwasada S, Torii S, Iwata H
    • Journal Title

      J Bone Joint Surg Br. 85-B

      Pages: 191-198

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Pedicle bone grafting versus transtrochanteric rotational osteotomy for avascular necrosis of the femoral head2003

    • Author(s)
      Yukiharu Hasegawa, Shinji Sakano, Toshiki Iwase, Seiki Iwasada, Shuhei Torii, Hisashi Iwata et al.
    • Journal Title

      J Bone Joint Surg Br. 85-B

      Pages: 191-198

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Book] Psychology of Moods2005

    • Author(s)
      Anita V. Clark
    • Total Pages
      191
    • Publisher
      New York : Nova Science Publishers
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Book] Mood changes and higher cognitive function in patients hospitalized for hip fracture and spinal disease.2005

    • Author(s)
      Takeshi Hatta, Yukiharu Hasegawa, Yukihiro Matsuyama et al.
    • Total Pages
      191
    • Publisher
      Anita V. Clark, New York : Nova Science Publishers
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Publications] 増井徹男ほか: "一般住民における重心動揺の経年的変化"日整会誌. 77(4). S258-S258 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 山口 仁ほか: "地域住民における骨密度の縦断的研究"日整会誌. 77(4). S557-S557 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 坪井真幸ほか: "地域高齢者におけるSF36を用いたQOLの測定"日整会誌. 77(4). S561-S561 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 辻 太一ほか: "中高年の腰痛の疫学的研究"日整会誌. 77(4). S622-S622 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 川崎雅史ほか: "中・高齢者における健脚度"日整会誌. 77(4). S660-S660 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 藁科秀紀ほか: "高齢者の転倒は身体運動能力の低下に関連する"日整会誌. 77(4). S660-S660 (2003)

    • Related Report
      2003 Annual Research Report

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Published: 2003-04-01   Modified: 2016-04-21  

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