Clinical and epidemiological study on the endemic neurodegenerative diseases (parkinsonism-dementia complex : PDC) in the Kii peninsula of Japan, Guam island and Guadeloupe, French west Indies.
| Project/Area Number |
15406034
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 海外学術 |
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| Research Field |
Neurology
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| Research Institution | Mie University |
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Principal Investigator |
KUZUHARA Shigeki Mie University, Graduate School of Medicine, Neurology, Professor, 大学院・医学系研究科, 教授 (70111383)
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| Co-Investigator(Kenkyū-buntansha) |
NARITA Yugo Mie University Hospital, Neurology, Associate Professor, 医学部附属病院, 助教授 (50242954)
KOKUBO Yasumasa Mie University, Graduate School of Medicine, Neurology, Assistant Professor, 大学院・医学系研究科, 助手 (60263000)
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| Project Period (FY) |
2003 – 2005
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| Project Status |
Completed (Fiscal Year 2005)
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| Budget Amount *help |
¥9,700,000 (Direct Cost: ¥9,700,000)
Fiscal Year 2005: ¥2,800,000 (Direct Cost: ¥2,800,000)
Fiscal Year 2004: ¥2,800,000 (Direct Cost: ¥2,800,000)
Fiscal Year 2003: ¥4,100,000 (Direct Cost: ¥4,100,000)
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| Keywords | ALS / PDC / Neurological Intractable Disease / Food / Environment / Parkinsonism / Dementia / 認知症 |
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| Research Abstract |
In 2004 and 2005 we visited Guadeloupe, and examined 17 atypical Caribbean parkinsonism patients with a cooperation of professor Lannuzel, Guadeloupe University Hospital, and have found they were characterized by akinesia and frontal abulia without obvious rigidity, tremor, freezing, and seemed to be a different entity from PDC on Guam and Kii peninsula. Fruit and herb tea of Annona which are suspected as its cause are not consumed in Japan. We were invited to the "Neurodegenerative disorders on Guam and in the Pacific regions symposium" held on December 2-5, 2005, and talked on ALS-PDC in the Kii peninsula: clinical, neuropathological and epidemiological studies. Similarities and differences between Guamanian and Kii diseases and possible causes were discussed. PDC on Guam and PDC in Kii may be included in an entity.
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Report
(4 results)
Research Products
(19 results)
