| Budget Amount *help |
¥3,100,000 (Direct Cost: ¥3,100,000)
Fiscal Year 2004: ¥1,400,000 (Direct Cost: ¥1,400,000)
Fiscal Year 2003: ¥1,700,000 (Direct Cost: ¥1,700,000)
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| Research Abstract |
Negative ions are detected in forests, at spas, and near waterfalls. Many reports have been published that the negative ions improve the subjective feeling, comfort, fatigue and occupational efficiency, but few evidence of the mechanism have been reported yet. To investigate the physiological effect of negative air ion for humans, we analyzed the hormonal and immunological changes.
In the artificiall climate room (25 degree centigrate, 50% humidity), young healthy volunteer were double-blindly exposed in negative-ion rich air (>10,000counts/cc : produced by ionizer equipment) or not. They were installed ergo metric exercise (gradually increased 20W/min). We tested hormonal (adrenalin, noradrenalin, dopamine, cortisol and serotonin), immunological stress responses (white blood cell and lymphocyte subsets) and metabolic products (pyrubic acids and lactic acids). Paired t-test was used for statistical analysis. There were no statistical differences in O2 consumption of maximum and of VT (v
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entilatory threshold) points. Negative air ions decreased the hormonal stress response and decreased dopamine level at 15 min after exercise (p<0.05) and diminished the pyrubic acid and lactic acid at the max exercise (p<0.05). And negative air ions diminished the immunological stress response (total white blood cells, NK subsets).
In another examination, 17 healthy male students were double-blindly exposed both negative ion rich air and control air. They were analyzed visual analogue scale (VAS) and local perspiration of palm (SKD2000, Skinos Co.) with mental stress (calculation etc.) test and 10 minutes pinprick stimulation by Chinese medical doctor.
Negative air ions significantly reduced VAS ; 22.2%(SE 3.3%) in negative air ions and 31.8%(SE5.6%) in control. And negative air ions significantly reduced local perspiration.
These dataa supported many reviews and suggested that the negative ions improved the metabolic efficiency of human and sympathetic nerve function. So we would need the further evidence of the ions effects. Less
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