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Effect of resistance taming on sympathetic nervous function in humans

Research Project

Project/Area Number 15500464
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Sports science
Research InstitutionToyota Technological Institute

Principal Investigator

SAITO Mitsuru  Toyota Technological Institute, School of Engineering, Professor, 工学部, 教授 (80126862)

Project Period (FY) 2003 – 2004
Project Status Completed (Fiscal Year 2004)
Budget Amount *help
¥3,500,000 (Direct Cost: ¥3,500,000)
Fiscal Year 2004: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 2003: ¥3,000,000 (Direct Cost: ¥3,000,000)
KeywordsMuscle symoathetic nerve activity / Heart rate / Central command / Cardiopulmonary baroreflex / Muscle metaboreflex / Muscle blood flow / Arterial baroreflex / Handgrip exercise / 代謝受容器反射
Research Abstract

Resistance training develops not only muscular strength but also improving physiological function such as autonomic control system. However, rationale or the mechanisms are not clear. A goal of this project was to investigate how resistance-training influence muscle sympathetic nerve activity (MSNA) and cardiovascular response during exercise.
High intensity handgrip exercise was used as resistance training. Unilateral (nondominant arm) handgrip training, which composed 3 set of 14 times of 10-sec maximal voluntary isometric contraction, was performed three days per week for 4 weeks. The training lead to increased maximal handgrip force in trained as well as untrained arm.
Heart rate and MSNA response during 10 times intermittent static handgrip for 15 seconds performed with voluntary maximum effort was investigated before and after training. After training heart rate response to the handgrip increased for trained arm exercise and also for untrained arm exercise. MSNA was increased durin … More g contractions of either trained or untrained arm and the onset of the response was earlier than that before training. This suggests that cardiovascular and sympathetic nervous response may be due to central command that was generated in the higher brain center rather than muscle reflex.
Effect of resistance training on muscle metaboreflex was tested during two minutes post exercise arterial occlusion followed rhythmic handgrip for one minute performed with maximal effort under the forearm ischemia. Although before training dominant arm exercise had a greater metaboreflex MSNA response than that of nondominant armor The MSNA response for trained arm (nondominant arm), but not untrained arm (control side) enhanced after training, while the size of response was not different between the arms.
This study demonstrated that resistance training have great effect on heart rate and sympathetic nervous system. From these results suggest that strong exercise effort even if active muscle mass was small involved during exercise play an important role to cardiovascular control system. Less

Report

(3 results)
  • 2004 Annual Research Report   Final Research Report Summary
  • 2003 Annual Research Report
  • Research Products

    (31 results)

All 2005 2004 2003 Other

All Journal Article (28 results) Publications (3 results)

  • [Journal Article] 軽強度自転車運動時の下肢筋血流に及ぼす下半身陰圧負荷の影響2005

    • Author(s)
      斉藤 満, 古谷克司, 城 宏
    • Journal Title

      日本運動生理学雑誌 12

      Pages: 13-21

    • NAID

      110002695428

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Annual Research Report 2004 Final Research Report Summary
  • [Journal Article] Effect of LBNP stimulation on leg muscle blood flow during low intensity cycling exercise.2005

    • Author(s)
      Mitsuru Sairo, Katsushi Furutani, Hiroshi Tachi
    • Journal Title

      J.Exercise Sports Physiol. 12

      Pages: 13-21

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Effects of resistance training on muscle sympathetic nerve response to static contraction2004

    • Author(s)
      Saito Mitsuru
    • Journal Title

      The Physiologist 47

      Pages: 280-281

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Annual Research Report 2004 Final Research Report Summary
  • [Journal Article] 運動および安静時の交感神経活動に対する身体トレーニングの効果 -Microneurographyによる研究-2004

    • Author(s)
      斉藤 満
    • Journal Title

      東海保健体育科学 26

      Pages: 1-8

    • NAID

      40006697334

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Annual Research Report 2004 Final Research Report Summary
  • [Journal Article] Modulation of control of muscle sympathetic nerve activity during orthostatic stress in humans2004

    • Author(s)
      Ichinose, M., Saito M., Ogawa, T., Hayashi, K., Kondo, N., Nishiyasu, T.
    • Journal Title

      Am.J.Physiol.Heart Circ.Physiol. 287

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Modulation of arterial baroreflex dynamic response during mild orthostatic stress in humans2004

    • Author(s)
      Ichinose, M., Saito M., Kitano, A., Hayashi, K., Kondo, N., Nishiyasu, T
    • Journal Title

      J.Physiol.Lond. 557

      Pages: 321-330

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Modulation of arterial baroreflex control of musclesympathetic nerve activity by muscle metaboreflex in humans.2004

    • Author(s)
      Ichinose, M., Saito M., Wada, H., Kitano, A., Kondo, N., Nishiyasu, T
    • Journal Title

      Am.J.Physiol.Heart Circ.Physiol. 286

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Changes in superficial blood distribution in thigh muscle during LBNP assessed by NIRS.2004

    • Author(s)
      Hachiya, T., Blaber, A., M.Saito.
    • Journal Title

      Aviat Space Environ Med 75

      Pages: 118-122

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] ハンドグリップ運動時における動脈圧受容器反射調節の経時的変化 -筋交感神経活動からみて2004

    • Author(s)
      一之瀬真志, 斉藤 満, 近藤徳彦, 西保 岳
    • Journal Title

      体力科学 53

      Pages: 711-711

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Modulation of arterial baroreflex control of muscle sympathetic nerve activity by muscle metaboreflex in humans.2004

    • Author(s)
      Masashi Ichinose, Mitsuru Saito, Hiroyuki Wada, Asa it Kitano, Narihiko Kondo, Takeshi Nishiyasu
    • Journal Title

      Am.J.Physiol.Heart Circ.Physiol. 286(6)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Changes in superficial blood distribution in thigh muscle during LBNP assessed by NIRS.2004

    • Author(s)
      Tessin Hachiya, Andrew P. Blaber, Mitsuru Saito
    • Journal Title

      Aviat Space Environ Med 75

      Pages: 118-122

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Mitsuru Modulation of arterial baroreflex dynamic response during mild orthostatic stress in humans.2004

    • Author(s)
      Masashi Ichinose, Mitsuru Saito, Asami Kitano, Keiji Hayashi, Narihiko Kondo, T. Nishiyasu
    • Journal Title

      J.Physiol.Lond. 557(1)

      Pages: 321-330

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Effects of resistance training on muscle sympathetic nerve response to static contraction2004

    • Author(s)
      Mitsuru Saito
    • Journal Title

      The Physiologist 47(4)

      Pages: 280-281

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Dynamic changes in the arterial baroreflex response control during handgrip exercise with respect to the muscle sympathetic nerve activity study.2004

    • Author(s)
      Masashi Ichinose, Mitsuru Saito, Narihiko Kondo, Takeshi Nishiyasu
    • Journal Title

      J.Phys.Fitness Sports Med. 53(6)

      Pages: 711-711

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Modulation of control of muscle sympathetic nerve activity during orthostatic stress in humans.2004

    • Author(s)
      Masashi Icinose, Misturu.Saito, Takeshi Ogawa, Keiji Hayashi, Narihiko Kondo, Takeshi Nishiyasu
    • Journal Title

      Am.J.Physiol.Heart Circ.Physiol. 287

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Effects of physical training on sympathetic nervous activity at rest and during exercise : microneurographic studies.2004

    • Author(s)
      Misturu Saito
    • Journal Title

      Tokai Hokentaiikukagaku 26

      Pages: 1-8

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Modulation of control of muscle sympathetic nerve activity during orthostatic stress in humans2004

    • Author(s)
      Ichnose, M., Saito M., Ogawa, T., Hayashi, K., Kondo, N., Nishiyasu, T.
    • Journal Title

      Am.J.Physiol.Heart Circ.Physiol. 287

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Modulation of arterial baroreflex dynamic response during mild orthostatic stress in humans2004

    • Author(s)
      Ichnose, M., Saito M., Kitano, A., Hayashi, K., Kondo, N., Nishiyasu, T.
    • Journal Title

      J.Physiol.Lond. 557

      Pages: 321-330

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Comparison of metaboreflex MSNA response between the right and the left arm exercise before and after muscle training.2003

    • Author(s)
      M.Saito
    • Journal Title

      Adv.Exer.Sports Physiol. 9

      Pages: 186-186

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Modulation of arterialbaroreflex dynamic response during orthostatic stress in humans.2003

    • Author(s)
      Ichinose, M., M.Saito, N.Kondo, T.Nishiyasu.
    • Journal Title

      Adv.Exer.Sports Physiol. 9

      Pages: 186-186

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] 深部体温と皮膚温が筋交感神経活動へ及ぼす影響2003

    • Author(s)
      林 恵嗣, 斉藤 満, 小川剛司, 一之瀬真志, 近藤徳彦, 西保 岳
    • Journal Title

      体力科学 52

      Pages: 720-720

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] 異なる2種類の陽圧呼吸法が循環系に及ぼす影響2003

    • Author(s)
      和田浩幸, 斉藤 満, 一之瀬真志, 近藤徳彦, 西保 岳
    • Journal Title

      体力科学 52

      Pages: 887-887

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] 起立性ストレス下での筋交感神経活動と心拍調節の関係2003

    • Author(s)
      一之瀬真志, 斉藤 満, 林 恵嗣, 和田浩幸, 近藤徳彦, 西保 岳
    • Journal Title

      体力科学 (6):、2003 52

      Pages: 893-893

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Comparison of metaboreflex MSNA response between the right and the left arm exercise before and after muscle training.2003

    • Author(s)
      Mitsuru Saito
    • Journal Title

      Adv.Exer.Sports Physiol. 9(4)

      Pages: 186-186

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Modulation of arterialbaroreflex dynamic response during orthostatic stress in humans.2003

    • Author(s)
      Masashi Ichinose, Mitsuru Saito, Narihiko Kondo, Takeshi Nishiyasu
    • Journal Title

      Adv.Exer.Sports Physiol. 9(4)

      Pages: 186-186

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Effect of orthostatic stress on relationship between muscle sympathetic nerve activity and heart rate control.2003

    • Author(s)
      Masashi Ichinose, Mitturu Saito, Keiji Hayashi, Kouji Wada, Narihiko Kondo, Takeshi Nishiyasu
    • Journal Title

      Jpn.J.Phys.Fitness Sports Med. 52(6)

      Pages: 893-893

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Effect of two different intensities of positive breathing on cardiovascular response.2003

    • Author(s)
      Kouji Wada, Mitsuru Saito, Masashi Ichinose, Narihiko Kondo, Takeshi Nishiyasu
    • Journal Title

      Jpn.J.Phys.Fitness Sports Med. 52(6)

      Pages: 887-887

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Effect of skin and body core temperature on muscle sympathetic nerve activity at rest.2003

    • Author(s)
      Keiji Hayashi, Mitsuru Saito, Takeshi Ogawa, Masashi Ichinose, Narihiko Kondo, Takeshi Nishiyasu
    • Journal Title

      Jpn.J.Phys.Fitness Sports Med. 52(6)

      Pages: 720-720

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Publications] Saito, M.: "Comparison of metaboreflex MSNA response between the right and the left arm exercise before and after muscle training."Adv.Exerc.Sports Physiol.. 9. 186 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] Hachiya, T., A.Blaber, M.Saito: "Changes in superficial blood distribution in thigh muscle during LBNP assessed by MIRS."Aviat.Space Environ.Med.. 75. 118-122 (2004)

    • Related Report
      2003 Annual Research Report
  • [Publications] Ichinose, M., M.Saito, H.Wada, A.Kitano, N.Kondo, T.Nishiyasu: "Modulation of arterial baroreflex control of muscle sympathetic nerve activity by muscle metaboreflex in humans."Am.J.Physiol.Heart Circ.Physiol.. 286. 701-707 (2004)

    • Related Report
      2003 Annual Research Report

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Published: 2003-04-01   Modified: 2016-04-21  

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