| Project/Area Number |
15500476
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied health science
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| Research Institution | Nagoya University |
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Principal Investigator |
OHSAWA Isao Nagoya University, Research Center of Health, Physical Fitness and Sports, Associate Professor, 総合保健体育科学センター, 助教授 (10223786)
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| Co-Investigator(Kenkyū-buntansha) |
OSHIDA Yoshiharu Nagoya University, Research Center of Health, Physical Fitness and Sports, Professor, 総合保健体育科学センター, 教授 (10169295)
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| Project Period (FY) |
2003 – 2004
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| Project Status |
Completed (Fiscal Year 2004)
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| Budget Amount *help |
¥2,100,000 (Direct Cost: ¥2,100,000)
Fiscal Year 2004: ¥700,000 (Direct Cost: ¥700,000)
Fiscal Year 2003: ¥1,400,000 (Direct Cost: ¥1,400,000)
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| Keywords | exercise / physical activity / diabetes mellitus / hypertension / malignant neoplasm / cancer / clinical epidemiology / EBM |
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| Research Abstract |
Through MEDLINE searches, we retrieved and reviewed English-language articles about the effectiveness of exercise and physical activity on diabetes mellitus, hypertension and malignant neoplasm.
1.Diabetes mellitus (randomized controlled trials between 1985 and 2003)
Three mega trials revealed that active life style reduced the incidence of type 2 diabetes. Fourteen out of 23 articles reported that HbAlc levels were significantly decreased in exercise group compared to control group.
2.Hypertension (randomized controlled trials between 2000 and 2004)
There were 12 articles that showed the beneficial effect of exercise on blood pressure among 21 articles. But the effects of exercise were weaker than those of diuretics and dietary sodium reduction.
3.Malignant neoplasm (prospective cohort studies between 2000 and 2004)
Four out of 7 articles showed that those who were physically active had lower cancer mortality. Inverse relationships were observed between active life style and risks for breast, colorectal, endometrial, and pancreatic cancers. The results were inconsistent about the associations of physical activity with risks of prostate, ovarian, renal cell, and bladder cancers.
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